Airway epithelial cells - Functional links between CFTR and anoctamin dependent Cl- secretion

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 11, 2012, Pages 1897-1900

  Kunzelmann, Karl ^a   Tian, Yuemin ^a   Martins, Joana Raquel ^a   Faria, Diana ^a   Kongsuphol, Patthara ^a   Ousingsawat, Jiraporn ^a   Wolf, Luisa ^a   Schreiber, Rainer ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Ano1; Anoctamin; CaCC; CFTR; Crosstalk; TMEM16A

Indexed keywords

ANOCTAMIN; CALCIUM; CHLORIDE CHANNEL; CYCLIC AMP; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

CLARA CELL; CYSTIC FIBROSIS; EPITHELIUM CELL; HUMAN; MUCOCILIARY CLEARANCE; NONHUMAN; PLASTICITY; RESPIRATORY EPITHELIUM; REVIEW;

EID: 84864521244     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.06.011     Document Type: Short Survey

References (24)

1. 2+ dependent ion channels TMEM16A and SK4 Pflugers Archiv 459 2009 485 497
2. 2+ signaling in non-excitable cells Cell Calcium 34 2003 431 444
3. D. Faria, R. Schreiber, and K. Kunzelmann CFTR is activated through stimulation of purinergic P2Y2 receptors Pflugers Archiv 457 2009 1373 1380
4. R. Greger, K. Kunzelmann, and L. Gerlach Mechanisms of chloride transport in secretory epithelia Annals of the New York Academy of Sciences 574 1990 403 415
5. - secretion in nasal epithelia of CF mice The American Journal of Physiology 266 1994 C1478 C1483
6. W.B. Guggino, and B.A. Stanton New insights into cystic fibrosis: molecular switches that regulate CFTR Nature Reviews: Molecular Cell Biology 7 2006 426 436
7. M.I. Hollenhorst, K. Richter, and M. Fronius Ion transport by pulmonary epithelia Journal of Biomedicine and Biotechnology 2011 2011 174306
8. P. Kongsuphol, R. Schreiber, K. Kraidith, and K. Kunzelmann CFTR induces extracellular acid sensing in Xenopus oocytes which activates endogenous Ca(2+)-activated Cl(-) conductance Pflugers Archiv 462 2011 479 487
9. S.M. Kreda, M. Mall, A. Mengos, L.G. Rochelle, J. Yankaskas, and J.R. Riordan CFTR in human airways Molecular Biology of the Cell 16 2005 2154 2167
10. 2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways The Journal of Clinical Investigation 120 2010 3137 3148
11. + channels in human normal and cystic fibrosis airway epithelia Pediatric Research 53 2003 608 618
12. J.R. Martins, D. Faria, P. Kongsuphol, B. Reisch, R. Schreiber, and K. Kunzelmann Anoctamin 6 is an essential component of the outwardly rectifying chloride channel Proceedings of the National Academy of Sciences of the United States of America 2011
13. - conductance in cystic fibrosis. Biochimica et Biophysica Acta, in press.
14. W. Namkung, W.E. Finkbeiner, and A.S. Verkman CFTR-adenylyl cyclase I association is responsible for UTP activation of CFTR in well-differentiated primary human bronchial cell cultures Molecular Biology of the Cell 21 2010 2639 2648
15. W. Namkung, Z. Yao, W.E. Finkbeiner, and A.S. Verkman Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction The FASEB Journal 2011
16. 2+ dependent chloride transport The Journal of Biological Chemistry 284 2009 28698 28703
17. J. Ousingsawat, P. Kongsuphol, R. Schreiber, and K. Kunzelmann CFTR and TMEM16A are separate but functionally related Cl channels Cellular Physiology and Biochemistry 28 2011 715 724
18. A.M. Paradiso, C.M. Ribeiro, and R.C. Boucher Polarized signaling via purinoceptors in normal and cystic fibrosis airway epithelia The Journal of General Physiology 117 2001 53 68
19. i signals in human cystic fibrosis airway epithelia The Journal of Biological Chemistry 2005
20. - - secretory channel in mouse airways The Journal of Biological Chemistry 284 2009 14875 14880
21. - secretion in mouse trachea Cellular Physiology and Biochemistry 16 2005 99 108
22. R. Schreiber, I. Uliyakina, P. Kongsuphol, R. Warth, M. Mirza, and J.R. Martins Function of epithelial anoctamins The Journal of Biological Chemistry 285 2010 7838 7845
23. Y.D. Yang, H. Cho, J.Y. Koo, M.H. Tak, Y. Cho, and W.S. Shim TMEM16A confers receptor-activated calcium-dependent chloride conductance Nature 455 2008 1210 1215
24. 3-secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct The Journal of Clinical Investigation 119 2009 193 202