Structural changes of CFTR R region upon phosphorylation: A plastic platform for intramolecular and intermolecular interactions

FEBS Journal

Volumn 280, Issue 18, 2013, Pages 4407-4416

  Bozoky, Zoltan ^a,b   Krzeminski, Mickael ^a,b   Chong, P Andrew ^a,b   Forman Kay, Julie D ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

binding; disordered; hub; IDP; post translational modification; regulation

Indexed keywords

CHLORIDE CHANNEL; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE;

BINDING KINETICS; CELL MEMBRANE TRANSPORT; CHANNEL GATING; DIMERIZATION; INTERMOLECULAR INTERACTION; INTRAMOLECULAR INTERACTION; MOLECULAR INTERACTION; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN TARGETING; REGULATORY MECHANISM; REVIEW;

BINDING; DISORDERED; HUB; IDP; POST-TRANSLATIONAL MODIFICATION; REGULATION;

BINDING SITES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 84883454123     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12422     Document Type: Review

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