메뉴 건너뛰기




Volumn 2, Issue 4, 1996, Pages 467-469

Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC G 418; CHLORIDE CHANNEL; CYCLIC AMP; GENTAMICIN; PHENYLALANINE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 0029994529     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0496-467     Document Type: Article
Times cited : (427)

References (20)
  • 1
    • 0025805098 scopus 로고
    • The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons
    • Skuzeski, J.M., Nichols, L.M., Gesteland, R.F. & Atkins, J.F. The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons. J. Mol. Biol. 218, 365-373 (1991).
    • (1991) J. Mol. Biol. , vol.218 , pp. 365-373
    • Skuzeski, J.M.1    Nichols, L.M.2    Gesteland, R.F.3    Atkins, J.F.4
  • 2
    • 0028821311 scopus 로고
    • The identity of the base following the stop codon determines the efficiency of in vivo translation termination in Escherichia coli
    • Poole, E.S., Brown, C.M. & Tate, W.P. The identity of the base following the stop codon determines the efficiency of in vivo translation termination in Escherichia coli. EMBO J. 14, 151-158 (1995).
    • (1995) EMBO J , vol.14 , pp. 151-158
    • Poole, E.S.1    Brown, C.M.2    Tate, W.P.3
  • 3
    • 0029047851 scopus 로고
    • Translational termination efficiency in mammals is influenced by the base following the stop codon
    • McCaughan, K.K., Brown, CM., Dalphin, M.E., Berry, M.J. & Tate, W.P. Translational termination efficiency in mammals is influenced by the base following the stop codon. Proc. Natl. Acad. Sci. USA 92, 5431-5435 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5431-5435
    • McCaughan, K.K.1    Brown, C.M.2    Dalphin, M.E.3    Berry, M.J.4    Tate, W.P.5
  • 4
    • 0029153552 scopus 로고
    • The efficiency of translation termination is determined by a synergistic interplay between upstream and down-stream sequences in Saccharomyces cerevisiae
    • Bonetti, B., Fu, L., Moon, J. & Bedwell, D.M. The efficiency of translation termination is determined by a synergistic interplay between upstream and down-stream sequences in Saccharomyces cerevisiae. J. Mol. Biol. 251, 334-345 (1995).
    • (1995) J. Mol. Biol. , vol.251 , pp. 334-345
    • Bonetti, B.1    Fu, L.2    Moon, J.3    Bedwell, D.M.4
  • 5
    • 0025310336 scopus 로고
    • A cluster of cystic fibrosis mutations in the first nucleotidebinding fold of the cystic fibrosis conductance regulator protein
    • Cutting, G.R. et al. A cluster of cystic fibrosis mutations in the first nucleotidebinding fold of the cystic fibrosis conductance regulator protein. Nature 346, 366-369 (1990).
    • (1990) Nature , vol.346 , pp. 366-369
    • Cutting, G.R.1
  • 6
    • 0025133518 scopus 로고
    • Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
    • Kerem, B.-S. et al. Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene. Proc. Natl. Acad. Sci. USA 87, 8447-8451 (1990).
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8447-8451
    • Kerem, B.-S.1
  • 7
    • 0000233999 scopus 로고
    • Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase
    • Fuerst, T.R., Niles, E.G., Studier, F.W. & Moss, B. Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc. Natl. Acad. Sci. USA 83, 8122-8126 (1986).
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8122-8126
    • Fuerst, T.R.1    Niles, E.G.2    Studier, F.W.3    Moss, B.4
  • 8
    • 0029177870 scopus 로고
    • Epitope tagging permits cell surface detection of functional CFTR
    • Howard, M. et al. Epitope tagging permits cell surface detection of functional CFTR. Am. J. Physiol. 38, C1565-C1576 (1995).
    • (1995) Am. J. Physiol. , vol.38
    • Howard, M.1
  • 9
    • 0027209522 scopus 로고
    • Molecular basis of defective anion transport in L cells
    • Yang, Y. et al. Molecular basis of defective anion transport in L cells. Hum. Mol. Genet. 2, 1253-1261 (1993).
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 1253-1261
    • Yang, Y.1
  • 10
    • 0002751916 scopus 로고
    • Misreading of RNA codewords induced by aminoglycoside antibiotics
    • Davies, J., Gorini, L. & Davis, B.D. Misreading of RNA codewords induced by aminoglycoside antibiotics. Mol. Pharinacol. 1, 93-106 (1965).
    • (1965) Mol. Pharinacol. , vol.1 , pp. 93-106
    • Davies, J.1    Gorini, L.2    Davis, B.D.3
  • 11
    • 0018344962 scopus 로고
    • Phenotypic suppression and misreading in Saccharomyces cerevisiae
    • Singh, A., Ursic, D. & Davies, J. Phenotypic suppression and misreading in Saccharomyces cerevisiae. Nature 277, 146-148 (1979).
    • (1979) Nature , vol.277 , pp. 146-148
    • Singh, A.1    Ursic, D.2    Davies, J.3
  • 12
    • 0018379922 scopus 로고
    • Phenotypic suppression of nonsense mutants in yeast by aminoglycoside antibiotics
    • Palmer, E., Wilhelm, J.M. & Sherman, F. Phenotypic suppression of nonsense mutants in yeast by aminoglycoside antibiotics. Nature 277, 148-150 (1979).
    • (1979) Nature , vol.277 , pp. 148-150
    • Palmer, E.1    Wilhelm, J.M.2    Sherman, F.3
  • 13
    • 0024379177 scopus 로고
    • Aminoglycoside suppression at UAG, UAA and UGA codons in Escherchia coli and human tissue culture cells
    • Martin, R., Mogg, A.E., Heywood, L.A., Nitschke, L. & Burke, J.F. Aminoglycoside suppression at UAG, UAA and UGA codons in Escherchia coli and human tissue culture cells. Mol. Gen. Genet. 217, 411-418 (1989).
    • (1989) Mol. Gen. Genet. , vol.217 , pp. 411-418
    • Martin, R.1    Mogg, A.E.2    Heywood, L.A.3    Nitschke, L.4    Burke, J.F.5
  • 14
    • 0027448163 scopus 로고
    • Spectrum of mutations in cystic fibrosis
    • Cutting, G.R. Spectrum of mutations in cystic fibrosis. J. Bioenerg. Biomembr. 25, 7-10 (1993).
    • (1993) J. Bioenerg. Biomembr. , vol.25 , pp. 7-10
    • Cutting, G.R.1
  • 15
    • 0028033069 scopus 로고
    • Cystic Fibrosis Genetic Analysis Consortium. Population variation of common cystic fibrosis mutations
    • Cystic Fibrosis Genetic Analysis Consortium. Population variation of common cystic fibrosis mutations. Hum. Mutat. 4, 167-177 (1994).
    • (1994) Hum. Mutat. , vol.4 , pp. 167-177
  • 16
    • 0028242356 scopus 로고
    • Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family
    • Fearon, K., McClendon, V., Bonetti, B. & Bedwell, D.M. Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family. J. Biol. Chem. 269, 17802-17808 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 17802-17808
    • Fearon, K.1    McClendon, V.2    Bonetti, B.3    Bedwell, D.M.4
  • 17
    • 0023770831 scopus 로고
    • Transfer ribonucleic acid-mediated suppression of termination codons in Escherichia coli
    • Eggertsson, G. & Soil, D. Transfer ribonucleic acid-mediated suppression of termination codons in Escherichia coli. Microbiol. Rev. 52, 354-374 (1988).
    • (1988) Microbiol. Rev. , vol.52 , pp. 354-374
    • Eggertsson, G.1    Soil, D.2
  • 18
    • 0001471317 scopus 로고
    • Suppression in the yeast Saccharomyces cerevisiae
    • eds. Strathern, J.N., Jones, E.W. & Broach, J.R. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
    • Sherman, F. Suppression in the yeast Saccharomyces cerevisiae. in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, (eds. Strathern, J.N., Jones, E.W. & Broach, J.R.) 463-486 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1982).
    • (1982) The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression , pp. 463-486
    • Sherman, F.1
  • 20
    • 0026503640 scopus 로고
    • Association of a nonsense mutation (W1282X), the most common mutation in the Ashkenazi Jewish cystic fibrosis patients in Israel, with presentation of severe disease
    • Shoshani, T. et al. Association of a nonsense mutation (W1282X), the most common mutation in the Ashkenazi Jewish cystic fibrosis patients in Israel, with presentation of severe disease. Am. J. Hum. Genet. 50, 222-228 (1992).
    • (1992) Am. J. Hum. Genet. , vol.50 , pp. 222-228
    • Shoshani, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.