-
1
-
-
0025183708
-
Basic local alignment search tool
-
Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 1990, 215:403-410.
-
(1990)
J. Mol. Biol.
, vol.215
, pp. 403-410
-
-
Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
-
2
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
-
Altschul S.F., et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 1997, 25:3389-3402.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
-
3
-
-
77954257799
-
ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids
-
Ashkenazy H., Erez E., Martz E., Pupko T., Ben-Tal N. ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids. Nucleic Acids Res. 2010, 38:W529-W533.
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Ashkenazy, H.1
Erez, E.2
Martz, E.3
Pupko, T.4
Ben-Tal, N.5
-
4
-
-
34547652267
-
CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices
-
Baker J.M., et al. CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices. Nat. Struct. Mol. Biol. 2007, 14:738-745.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 738-745
-
-
Baker, J.M.1
-
6
-
-
3042681902
-
ConSeq: the identification of functionally and structurally important residues in protein sequences
-
Berezin C., et al. ConSeq: the identification of functionally and structurally important residues in protein sequences. Bioinformatics 2004, 20:1322-1324.
-
(2004)
Bioinformatics
, vol.20
, pp. 1322-1324
-
-
Berezin, C.1
-
7
-
-
26444482460
-
Molecular phylogeny and divergence times of deuterostome animals
-
Blair J.E., Hedges S.B. Molecular phylogeny and divergence times of deuterostome animals. Mol. Biol. Evol. 2005, 22:2275-2284.
-
(2005)
Mol. Biol. Evol.
, vol.22
, pp. 2275-2284
-
-
Blair, J.E.1
Hedges, S.B.2
-
8
-
-
84863988094
-
Proto-genes and de novo gene birth
-
Carvunis A.R., et al. Proto-genes and de novo gene birth. Nature 2012, 487:370-374.
-
(2012)
Nature
, vol.487
, pp. 370-374
-
-
Carvunis, A.R.1
-
9
-
-
0027311276
-
Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10PKA consensus phosphorylation sites
-
Chang X.B., et al. Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10PKA consensus phosphorylation sites. J. Biol. Chem. 1993, 268:11304-11311.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11304-11311
-
-
Chang, X.B.1
-
10
-
-
33244483948
-
Alternatively and constitutively spliced exons are subject to different evolutionary forces
-
Chen F.C., Wang S.S., Chen C.J., Li W.H., Chuang T.J. Alternatively and constitutively spliced exons are subject to different evolutionary forces. Mol. Biol. Evol. 2006, 23:675-682.
-
(2006)
Mol. Biol. Evol.
, vol.23
, pp. 675-682
-
-
Chen, F.C.1
Wang, S.S.2
Chen, C.J.3
Li, W.H.4
Chuang, T.J.5
-
11
-
-
0025987020
-
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel
-
Cheng S.H., Rich D.P., Marshall J., Gregory R.J., Welsh M.J., Smith A.E. Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell 1991, 66:1027-1036.
-
(1991)
Cell
, vol.66
, pp. 1027-1036
-
-
Cheng, S.H.1
Rich, D.P.2
Marshall, J.3
Gregory, R.J.4
Welsh, M.J.5
Smith, A.E.6
-
12
-
-
2142738304
-
WebLogo: a sequence logo generator
-
Crooks G.E., Hon G., Chandonia J.M., Brenner S.E. WebLogo: a sequence logo generator. Genome Res. 2004, 14:1188-1190.
-
(2004)
Genome Res.
, vol.14
, pp. 1188-1190
-
-
Crooks, G.E.1
Hon, G.2
Chandonia, J.M.3
Brenner, S.E.4
-
13
-
-
0035014565
-
The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms
-
Dassa E., Bouige P. The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms. Res. Microbiol. 2001, 152:211-229.
-
(2001)
Res. Microbiol.
, vol.152
, pp. 211-229
-
-
Dassa, E.1
Bouige, P.2
-
14
-
-
25844487733
-
Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates
-
Dean M., Annilo T. Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Annu. Rev. Genomics Hum. Genet. 2005, 6:123-142.
-
(2005)
Annu. Rev. Genomics Hum. Genet.
, vol.6
, pp. 123-142
-
-
Dean, M.1
Annilo, T.2
-
15
-
-
77957233168
-
Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology
-
Delport W., Poon A.F., Frost S.D., Kosakovsky Pond S.L. Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology. Bioinformatics 2010, 26:2455-2457.
-
(2010)
Bioinformatics
, vol.26
, pp. 2455-2457
-
-
Delport, W.1
Poon, A.F.2
Frost, S.D.3
Kosakovsky Pond, S.L.4
-
16
-
-
0028328645
-
Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator
-
Dulhanty A.M., Riordan J.R. Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator. Biochemistry 1994, 33:4072-4079.
-
(1994)
Biochemistry
, vol.33
, pp. 4072-4079
-
-
Dulhanty, A.M.1
Riordan, J.R.2
-
17
-
-
0032893932
-
Preservation of duplicate genes by complementary, degenerative mutations
-
Force A., Lynch M., Pickett F.B., Amores A., Yan Y.L., Postlethwait J. Preservation of duplicate genes by complementary, degenerative mutations. Genetics 1999, 151:1531-1545.
-
(1999)
Genetics
, vol.151
, pp. 1531-1545
-
-
Force, A.1
Lynch, M.2
Pickett, F.B.3
Amores, A.4
Yan, Y.L.5
Postlethwait, J.6
-
18
-
-
78651320424
-
The UCSC Genome Browser database: update 2011
-
Fujita P.A., et al. The UCSC Genome Browser database: update 2011. Nucleic Acids Res. 2011, 39:D876-D882.
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Fujita, P.A.1
-
20
-
-
0032936619
-
Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis
-
Gadsby D.C., Nairn A.C. Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis. Physiol. Rev. 1999, 79:S77-S107.
-
(1999)
Physiol. Rev.
, vol.79
-
-
Gadsby, D.C.1
Nairn, A.C.2
-
21
-
-
33645307384
-
The ABC protein turned chloride channel whose failure causes cystic fibrosis
-
Gadsby D.C., Vergani P., Csanady L. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 2006, 440:477-483.
-
(2006)
Nature
, vol.440
, pp. 477-483
-
-
Gadsby, D.C.1
Vergani, P.2
Csanady, L.3
-
22
-
-
0017771466
-
Evolution and tinkering
-
Jacob F. Evolution and tinkering. Science 1977, 196:1161-1166.
-
(1977)
Science
, vol.196
, pp. 1161-1166
-
-
Jacob, F.1
-
23
-
-
57749106719
-
Evolutionary and functional divergence between the cystic fibrosis transmembrane conductance regulator and related ATP-binding cassette transporters
-
Jordan I.K., Kota K.C., Cui G., Thompson C.H., McCarty N.A. Evolutionary and functional divergence between the cystic fibrosis transmembrane conductance regulator and related ATP-binding cassette transporters. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:18865-18870.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 18865-18870
-
-
Jordan, I.K.1
Kota, K.C.2
Cui, G.3
Thompson, C.H.4
McCarty, N.A.5
-
26
-
-
0034625153
-
A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution
-
Ostedgaard L.S., Baldursson O., Vermeer D.W., Welsh M.J., Robertson A.D. A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:5657-5662.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5657-5662
-
-
Ostedgaard, L.S.1
Baldursson, O.2
Vermeer, D.W.3
Welsh, M.J.4
Robertson, A.D.5
-
27
-
-
17744395033
-
Datamonkey: rapid detection of selective pressure on individual sites of codon alignments
-
Pond S.L., Frost S.D. Datamonkey: rapid detection of selective pressure on individual sites of codon alignments. Bioinformatics 2005, 21:2531-2533.
-
(2005)
Bioinformatics
, vol.21
, pp. 2531-2533
-
-
Pond, S.L.1
Frost, S.D.2
-
28
-
-
14544275616
-
A genetic algorithm approach to detecting lineage-specific variation in selection pressure
-
Pond S.L., Frost S.D. A genetic algorithm approach to detecting lineage-specific variation in selection pressure. Mol. Biol. Evol. 2005, 22:478-485.
-
(2005)
Mol. Biol. Evol.
, vol.22
, pp. 478-485
-
-
Pond, S.L.1
Frost, S.D.2
-
29
-
-
15844406550
-
HyPhy: hypothesis testing using phylogenies
-
Pond S.L., Frost S.D., Muse S.V. HyPhy: hypothesis testing using phylogenies. Bioinformatics 2005, 21:676-679.
-
(2005)
Bioinformatics
, vol.21
, pp. 676-679
-
-
Pond, S.L.1
Frost, S.D.2
Muse, S.V.3
-
30
-
-
58149178579
-
NCBI reference sequences: current status, policy and new initiatives
-
Pruitt K.D., Tatusova T., Klimke W., Maglott D.R. NCBI reference sequences: current status, policy and new initiatives. Nucleic Acids Res. 2009, 37:D32-D36.
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Pruitt, K.D.1
Tatusova, T.2
Klimke, W.3
Maglott, D.R.4
-
31
-
-
46149101497
-
Positive selection in alternatively spliced exons of human genes
-
Ramensky V.E., Nurtdinov R.N., Neverov A.D., Mironov A.A., Gelfand M.S. Positive selection in alternatively spliced exons of human genes. Am. J. Hum. Genet. 2008, 83:94-98.
-
(2008)
Am. J. Hum. Genet.
, vol.83
, pp. 94-98
-
-
Ramensky, V.E.1
Nurtdinov, R.N.2
Neverov, A.D.3
Mironov, A.A.4
Gelfand, M.S.5
-
32
-
-
0034201441
-
EMBOSS: the European Molecular Biology Open Software Suite
-
Rice P., Longden I., Bleasby A. EMBOSS: the European Molecular Biology Open Software Suite. Trends Genet. 2000, 16:276-277.
-
(2000)
Trends Genet.
, vol.16
, pp. 276-277
-
-
Rice, P.1
Longden, I.2
Bleasby, A.3
-
33
-
-
0027171978
-
- channel by negative charge in the R domain
-
- channel by negative charge in the R domain. J. Biol. Chem. 1993, 268:20259-20267.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20259-20267
-
-
Rich, D.P.1
-
34
-
-
0024453308
-
Identification of the cystic fibrosis gene: chromosome walking and jumping
-
Rommens J.M., et al. Identification of the cystic fibrosis gene: chromosome walking and jumping. Science 1989, 245:1059-1065.
-
(1989)
Science
, vol.245
, pp. 1059-1065
-
-
Rommens, J.M.1
-
35
-
-
0023375195
-
The neighbor-joining method: a new method for reconstructing phylogenetic trees
-
Saitou N., Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 1987, 4:406-425.
-
(1987)
Mol. Biol. Evol.
, vol.4
, pp. 406-425
-
-
Saitou, N.1
Nei, M.2
-
36
-
-
84857745267
-
Database resources of the National Center for Biotechnology Information
-
Sayers E.W., et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2012, 40:D13-D25.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Sayers, E.W.1
-
37
-
-
0032568655
-
SMART, a simple modular architecture research tool: identification of signaling domains
-
Schultz J., Milpetz F., Bork P., Ponting C.P. SMART, a simple modular architecture research tool: identification of signaling domains. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:5857-5864.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 5857-5864
-
-
Schultz, J.1
Milpetz, F.2
Bork, P.3
Ponting, C.P.4
-
38
-
-
42149120706
-
Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function
-
Serohijos A.W., et al. Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:3256-3261.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 3256-3261
-
-
Serohijos, A.W.1
-
39
-
-
79957613599
-
MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
-
Tamura K., Peterson D., Peterson N., Stecher G., Nei M., Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 2011, 28:2731-2739.
-
(2011)
Mol. Biol. Evol.
, vol.28
, pp. 2731-2739
-
-
Tamura, K.1
Peterson, D.2
Peterson, N.3
Stecher, G.4
Nei, M.5
Kumar, S.6
-
40
-
-
80052969570
-
The evolutionary origin of orphan genes
-
Tautz D., Domazet-Loso T. The evolutionary origin of orphan genes. Nat. Rev. Genet. 2011, 12:692-702.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 692-702
-
-
Tautz, D.1
Domazet-Loso, T.2
-
41
-
-
0027968068
-
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
-
Thompson J.D., Higgins D.G., Gibson T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994, 22:4673-4680.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
42
-
-
4143102419
-
Dibasic phosphorylation sites in the R domain of CFTR have stimulatory and inhibitory effects on channel activation
-
Vais H., Zhang R., Reenstra W.W. Dibasic phosphorylation sites in the R domain of CFTR have stimulatory and inhibitory effects on channel activation. Am. J. Physiol. Cell Physiol. 2004, 287:C737-C745.
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
-
-
Vais, H.1
Zhang, R.2
Reenstra, W.W.3
-
43
-
-
0030816586
-
CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain
-
Wilkinson D.J., et al. CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain. Am. J. Physiol. 1997, 273:L127-L133.
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Wilkinson, D.J.1
-
44
-
-
0032749078
-
Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm
-
Wright P.E., Dyson H.J. Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. J. Mol. Biol. 1999, 293:321-331.
-
(1999)
J. Mol. Biol.
, vol.293
, pp. 321-331
-
-
Wright, P.E.1
Dyson, H.J.2
-
45
-
-
81755187310
-
De novo origin of human protein-coding genes
-
Wu D.D., Irwin D.M., Zhang Y.P. De novo origin of human protein-coding genes. PLoS Genet. 2011, 7:e1002379.
-
(2011)
PLoS Genet.
, vol.7
-
-
Wu, D.D.1
Irwin, D.M.2
Zhang, Y.P.3
-
46
-
-
0037151094
-
A short segment of the R domain of cystic fibrosis transmembrane conductance regulator contains channel stimulatory and inhibitory activities that are separable by sequence modification
-
Xie J., Adams L.M., Zhao J., Gerken T.A., Davis P.B., Ma J. A short segment of the R domain of cystic fibrosis transmembrane conductance regulator contains channel stimulatory and inhibitory activities that are separable by sequence modification. J. Biol. Chem. 2002, 277:23019-23027.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23019-23027
-
-
Xie, J.1
Adams, L.M.2
Zhao, J.3
Gerken, T.A.4
Davis, P.B.5
Ma, J.6
-
47
-
-
20144376345
-
Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification
-
Yanai I., et al. Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification. Bioinformatics 2005, 21:650-659.
-
(2005)
Bioinformatics
, vol.21
, pp. 650-659
-
-
Yanai, I.1
|