Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cells

Nature Medicine

Volumn 8, Issue 5, 2002, Pages 485-492

  Egan, Marie E ^a,c   Glöckner Pagel, Judith ^c   Ambrose, Catherine A ^a   Cahill, Paula A ^a   Pappoe, Lamiko ^a   Balamuth, Naomi ^a   Cho, Edward ^c   Canny, Susan ^c   Wagner, Carsten A ^c   Geibel, John ^b,c   Caplan, Michael J ^c  

^a Departments of Pediatrics   (United States)

^b Department of Surgery ^*  (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATASE INHIBITOR; CALCIUM ION; CHAPERONE; CHLORIDE CHANNEL; CHLORIDE ION; THAPSIGARGIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; CYSTIC FIBROSIS; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; ION PERMEABILITY; MOUSE; NONHUMAN; NOSE MUCOSA; PATCH CLAMP; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; RESPIRATORY EPITHELIUM; TREATMENT OUTCOME;

AMILORIDE; CALCIUM CHANNEL BLOCKERS; CELL MEMBRANE; CELLS, CULTURED; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; ISOPROTERENOL; PATCH-CLAMP TECHNIQUES; SEQUENCE DELETION; THAPSIGARGIN;

ANIMALIA;

EID: 0036115199     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0502-485     Document Type: Article

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