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Volumn 302, Issue 11, 2012, Pages

The CFTR and ENaC debate: How important is ENaC in CF lung disease?

Author keywords

Cystic fibrosis; Mouse models; Pathogenesis; Sodium channel

Indexed keywords

EPITHELIAL SODIUM CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 84861879494     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00036.2012     Document Type: Article
Times cited : (67)

References (41)
  • 2
    • 0025871551 scopus 로고
    • Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia
    • Anderson MP, Welsh MJ. Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. Proc Natl Acad Sci USA 88: 6003-6007, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6003-6007
    • Anderson, M.P.1    Welsh, M.J.2
  • 4
    • 0022973473 scopus 로고
    • + transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation
    • + transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation. J Clin Invest 78: 1245-1252, 1986.
    • (1986) J Clin Invest , vol.78 , pp. 1245-1252
    • Boucher, R.C.1    Stutts, M.J.2    Knowles, M.R.3    Cantley, L.4    Gatzy, J.T.5
  • 7
    • 33645130994 scopus 로고    scopus 로고
    • Cystic fibrosis since 1938
    • Davis PB. Cystic fibrosis since 1938. Am J Respir Crit Care Med 173: 475-482, 2006.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 475-482
    • Davis, P.B.1
  • 8
    • 84857631596 scopus 로고    scopus 로고
    • Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways
    • Enuka Y, Hanukoglu I, Edelheit O, Vaknine H, Hanukoglu A. Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways. Histochem Cell Biol 137: 339-353, 2012.
    • (2012) Histochem Cell Biol , vol.137 , pp. 339-353
    • Enuka, Y.1    Hanukoglu, I.2    Edelheit, O.3    Vaknine, H.4    Hanukoglu, A.5
  • 9
    • 2442645035 scopus 로고    scopus 로고
    • Finally, mice with CF lung disease
    • Frizzell RA, Pilewski JM. Finally, mice with CF lung disease. Nat Med 10: 452-454, 2004.
    • (2004) Nat Med , vol.10 , pp. 452-454
    • Frizzell, R.A.1    Pilewski, J.M.2
  • 11
    • 0029821863 scopus 로고    scopus 로고
    • Regulation of epithelial ion channels by the cystic fibrosis transmembrane conductance regulator
    • Greger R, Mall M, Bleich M, Ecke D, Warth R, Riedemann N, Kunzelmann K. Regulation of epithelial ion channels by the cystic fibrosis transmembrane conductance regulator. J Mol Med 74: 527-534, 1996.
    • (1996) J Mol Med , vol.74 , pp. 527-534
    • Greger, R.1    Mall, M.2    Bleich, M.3    Ecke, D.4    Warth, R.5    Riedemann, N.6    Kunzelmann, K.7
  • 12
    • 0032962320 scopus 로고    scopus 로고
    • Pathophysiology of gene-targeted mouse models for cystic fibrosis
    • Grubb BR, Boucher RC. Pathophysiology of gene-targeted mouse models for cystic fibrosis. Physiol Rev 79: S193-S214, 1999.
    • (1999) Physiol Rev , vol.79
    • Grubb, B.R.1    Boucher, R.C.2
  • 19
    • 18244377969 scopus 로고    scopus 로고
    • Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia
    • Kreda SM, Mall M, Mengos A, Rochelle L, Yankaskas J, Riordan JR, Boucher RC. Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. Mol Biol Cell 16: 2154-2167, 2005.
    • (2005) Mol Biol Cell , vol.16 , pp. 2154-2167
    • Kreda, S.M.1    Mall, M.2    Mengos, A.3    Rochelle, L.4    Yankaskas, J.5    Riordan, J.R.6    Boucher, R.C.7
  • 22
    • 80053376536 scopus 로고    scopus 로고
    • Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung
    • Lazrak A, Jurkuvenaite A, Chen L, Keeling KM, Collawn JF, Bedwell DM, Matalon S. Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung. Am J Physiol Lung Cell Mol Physiol 301: L557-L567, 2011.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.301
    • Lazrak, A.1    Jurkuvenaite, A.2    Chen, L.3    Keeling, K.M.4    Collawn, J.F.5    Bedwell, D.M.6    Matalon, S.7
  • 23
    • 0032127980 scopus 로고    scopus 로고
    • + conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways
    • + conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways. J Clin Invest 102: 15-21, 1998.
    • (1998) J Clin Invest , vol.102 , pp. 15-21
    • Mall, M.1    Bleich, M.2    Greger, R.3    Schreiber, R.4    Kunzelmann, K.5
  • 26
    • 58449116969 scopus 로고    scopus 로고
    • + channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease
    • + channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease. Exp Physiol 94: 171-174, 2009.
    • (2009) Exp Physiol , vol.94 , pp. 171-174
    • Mall, M.A.1
  • 28
    • 0032433707 scopus 로고    scopus 로고
    • Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
    • Matsui H, Grubb BR, Tarran R, Randell SH, Gatzy JT, Davis CW, Boucher RC. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell 95: 1005-1015, 1998.
    • (1998) Cell , vol.95 , pp. 1005-1015
    • Matsui, H.1    Grubb, B.R.2    Tarran, R.3    Randell, S.H.4    Gatzy, J.T.5    Davis, C.W.6    Boucher, R.C.7
  • 30
    • 0034047238 scopus 로고    scopus 로고
    • French multicenter randomized double-blind placebo-controlled trial on nebulized amiloride in cystic fibrosis patients. The Amiloride-AFLM Collaborative Study Group
    • Pons G, Marchand MC, d'Athis P, Sauvage E, Foucard C, Chaumet-Riffaud P, Sautegeau A, Navarro J, Lenoir G. French multicenter randomized double-blind placebo-controlled trial on nebulized amiloride in cystic fibrosis patients. The Amiloride-AFLM Collaborative Study Group. Pediatr Pulmonol 30: 25-31, 2000.
    • (2000) Pediatr Pulmonol , vol.30 , pp. 25-31
    • Pons, G.1    Marchand, M.C.2    d'Athis, P.3    Sauvage, E.4    Foucard, C.5    Chaumet-Riffaud, P.6    Sautegeau, A.7    Navarro, J.8    Lenoir, G.9
  • 31
    • 0020700816 scopus 로고
    • Chloride impermeability in cystic fibrosis
    • Quinton PM. Chloride impermeability in cystic fibrosis. Nature 301: 421-422, 1983.
    • (1983) Nature , vol.301 , pp. 421-422
    • Quinton, P.M.1
  • 32
    • 48149090717 scopus 로고    scopus 로고
    • Cystic fibrosis: Impaired bicarbonate secretion and mucoviscidosis
    • Quinton PM. Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis. Lancet 372: 415-417, 2008.
    • (2008) Lancet , vol.372 , pp. 415-417
    • Quinton, P.M.1
  • 34
    • 0029870085 scopus 로고    scopus 로고
    • Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
    • Smith JJ, Travis SM, Greenberg EP, Welsh MJ. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 85: 229-236, 1996.
    • (1996) Cell , vol.85 , pp. 229-236
    • Smith, J.J.1    Travis, S.M.2    Greenberg, E.P.3    Welsh, M.J.4
  • 38
    • 36048955097 scopus 로고    scopus 로고
    • Murine tracheal and nasal septal epithelium for air-liquid interface cultures: A comparative study
    • Woodworth BA, Antunes MB, Bhargave G, Palmer JN, Cohen NA. Murine tracheal and nasal septal epithelium for air-liquid interface cultures: a comparative study. Am J Rhinol 21: 533-537, 2007.
    • (2007) Am J Rhinol , vol.21 , pp. 533-537
    • Woodworth, B.A.1    Antunes, M.B.2    Bhargave, G.3    Palmer, J.N.4    Cohen, N.A.5
  • 39
    • 2542500548 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator differentially regulates human and mouse epithelial sodium channels in Xenopus oocytes
    • Yan W, Samaha FF, Ramkumar M, Kleyman TR, Rubenstein RC. Cystic fibrosis transmembrane conductance regulator differentially regulates human and mouse epithelial sodium channels in Xenopus oocytes. J Biol Chem 279: 23183-23192, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 23183-23192
    • Yan, W.1    Samaha, F.F.2    Ramkumar, M.3    Kleyman, T.R.4    Rubenstein, R.C.5
  • 40
    • 0032160101 scopus 로고    scopus 로고
    • Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro
    • Zabner J, Smith JJ, Karp PH, Widdicombe JH, Welsh MJ. Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro. Mol Cell 2: 397-403, 1998.
    • (1998) Mol Cell , vol.2 , pp. 397-403
    • Zabner, J.1    Smith, J.J.2    Karp, P.H.3    Widdicombe, J.H.4    Welsh, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.