C-terminal truncations destabilize the cystic fibrosis transmembrane conductance regulator without impairing its biogenesis. A novel class of mutation

Journal of Biological Chemistry

Volumn 274, Issue 31, 1999, Pages 21873-21877

  Haardt, Martin ^c   Benharouga, Mohamed ^c   Lechardeur, Delphine ^c   Kartner, Norbert ^a   Lukacs, Gergely L ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CYSTIC FIBROSIS; ENDOPLASMIC RETICULUM; FRAMESHIFT MUTATION; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; CELL LINE; CELL MEMBRANE; CODON, TERMINATOR; COS CELLS; CRICETINAE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DATABASES, FACTUAL; DNA PRIMERS; FRAMESHIFT MUTATION; HETEROZYGOTE; HUMANS; MEMBRANE POTENTIALS; POLYMERASE CHAIN REACTION; PROTEIN FOLDING; RECOMBINANT PROTEINS; SEQUENCE DELETION; TRANSFECTION;

EID: 0033618404     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.31.21873     Document Type: Article

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