-
1
-
-
0001752544
-
Cystic Fibrosis
-
C. Scriver, A. Beaudet, D. Valle, McGraw-Hill New York
-
M. Welsh, and B. Ramsey Cystic Fibrosis C. Scriver, A. Beaudet, D. Valle, The Metabolic and Molecular Basis of Inherited Disease 2001 McGraw-Hill New York 5121 5188
-
(2001)
The Metabolic and Molecular Basis of Inherited Disease
, pp. 5121-5188
-
-
Welsh, M.1
Ramsey, B.2
-
2
-
-
0032934916
-
Role of CFTR in airway disease
-
J.M. Pilewski, and R.A. Frizzell Role of CFTR in airway disease Physiol. Rev. 79 1999 S215 S255
-
(1999)
Physiol. Rev.
, vol.79
, pp. S215-S255
-
-
Pilewski, J.M.1
Frizzell, R.A.2
-
3
-
-
0036258208
-
Cystic fibrosis: A worldwide analysis of CFTR mutations-correlation with incidence data and application to screening
-
J.L. Bobadilla, M. Macek Jr., J.P. Fine, and P.M. Farrell Cystic fibrosis: a worldwide analysis of CFTR mutations-correlation with incidence data and application to screening Hum. Mutat. 19 2002 575 606
-
(2002)
Hum. Mutat.
, vol.19
, pp. 575-606
-
-
Bobadilla, J.L.1
Macek, M.2
Fine, J.P.3
Farrell, P.M.4
-
4
-
-
0033361889
-
Cystic fibrosis as a disease of misprocessing of the cystic fibrosis transmembrane conductance regulator glycoprotein
-
J.R. Riordan Cystic fibrosis as a disease of misprocessing of the cystic fibrosis transmembrane conductance regulator glycoprotein Am. J. Hum. Genet. 64 1999 1499 1504
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 1499-1504
-
-
Riordan, J.R.1
-
5
-
-
0032957204
-
Biosynthesis and degradation of CFTR
-
R.R. Kopito Biosynthesis and degradation of CFTR Physiol. Rev. 79 1999 S167 S173
-
(1999)
Physiol. Rev.
, vol.79
, pp. S167-S173
-
-
Kopito, R.R.1
-
6
-
-
0026781952
-
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
-
G.M. Denning, M.P. Anderson, J.F. Amara, J. Marshall, A.E. Smith, and M.J. Welsh Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive Nature 358 1992 761 764
-
(1992)
Nature
, vol.358
, pp. 761-764
-
-
Denning, G.M.1
Anderson, M.P.2
Amara, J.F.3
Marshall, J.4
Smith, A.E.5
Welsh, M.J.6
-
7
-
-
0042317111
-
Nanomolar affinity small molecule correctors of defective delta F508-CFTR chloride channel gating
-
H. Yang, A.A. Shelat, R.K. Guy, V.S. Gopinath, T. Ma, K. Du, G.L. Lukacs, A. Taddei, C. Folli, N. Pedemonte, L.J. Galietta, and A.S. Verkman Nanomolar affinity small molecule correctors of defective delta F508-CFTR chloride channel gating J. Biol. Chem. 278 2003 35079 35085
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35079-35085
-
-
Yang, H.1
Shelat, A.A.2
Guy, R.K.3
Gopinath, V.S.4
Ma, T.5
Du, K.6
Lukacs, G.L.7
Taddei, A.8
Folli, C.9
Pedemonte, N.10
Galietta, L.J.11
Verkman, A.S.12
-
8
-
-
33744831154
-
Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules
-
F. Van Goor, K.S. Straley, D. Cao, J. Gonzalez, S. Hadida, A. Hazlewood, J. Joubran, T. Knapp, L.R. Makings, M. Miller, T. Neuberger, E. Olson, V. Panchenko, J. Rader, A. Singh, J.H. Stack, R. Tung, P.D. Grootenhuis, and P. Negulescu Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules Am. J. Physiol. Lung Cell. Mol. Physiol. 290 2006 L1117 L1130
-
(2006)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.290
, pp. L1117-L1130
-
-
Van Goor, F.1
Straley, K.S.2
Cao, D.3
Gonzalez, J.4
Hadida, S.5
Hazlewood, A.6
Joubran, J.7
Knapp, T.8
Makings, L.R.9
Miller, M.10
Neuberger, T.11
Olson, E.12
Panchenko, V.13
Rader, J.14
Singh, A.15
Stack, J.H.16
Tung, R.17
Grootenhuis, P.D.18
Negulescu, P.19
-
9
-
-
84856463093
-
Identification and validation of hits from high throughput screens for CFTR modulators
-
S. Pasyk, S. Molinski, W. Yu, P.D. Eckford, and C.E. Bear Identification and validation of hits from high throughput screens for CFTR modulators Curr. Pharm. Des. 18 2012 628 641
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 628-641
-
-
Pasyk, S.1
Molinski, S.2
Yu, W.3
Eckford, P.D.4
Bear, C.E.5
-
10
-
-
79958046677
-
Resveratrol rescues cAMP-dependent anionic transport in the cystic fibrosis pancreatic cell line CFPAC1
-
N. Hamdaoui, M. Baudoin-Legros, M. Kelly, A. Aissat, S. Moriceau, D.L. Vieu, J. Colas, J. Fritsch, A. Edelman, and G. Planelles Resveratrol rescues cAMP-dependent anionic transport in the cystic fibrosis pancreatic cell line CFPAC1 Br. J. Pharmacol. 163 2011 876 886
-
(2011)
Br. J. Pharmacol.
, vol.163
, pp. 876-886
-
-
Hamdaoui, N.1
Baudoin-Legros, M.2
Kelly, M.3
Aissat, A.4
Moriceau, S.5
Vieu, D.L.6
Colas, J.7
Fritsch, J.8
Edelman, A.9
Planelles, G.10
-
11
-
-
79958270724
-
Resveratrol has salutary effects on mucociliary transport and inflammation in sinonasal epithelium
-
N.S. Alexander, N. Hatch, S. Zhang, D. Skinner, J. Fortenberry, E.J. Sorscher, and B.A. Woodworth Resveratrol has salutary effects on mucociliary transport and inflammation in sinonasal epithelium Laryngoscope 121 2011 1313 1319
-
(2011)
Laryngoscope
, vol.121
, pp. 1313-1319
-
-
Alexander, N.S.1
Hatch, N.2
Zhang, S.3
Skinner, D.4
Fortenberry, J.5
Sorscher, E.J.6
Woodworth, B.A.7
-
12
-
-
84896709106
-
Resveratrol enhances airway surface liquid depth in sinonasal epithelium by increasing cystic fibrosis transmembrane conductance regulator open probability
-
S. Zhang, A.C. Blount, C.M. McNicholas, D.F. Skinner, M. Chestnut, J.C. Kappes, E.J. Sorscher, and B.A. Woodworth Resveratrol enhances airway surface liquid depth in sinonasal epithelium by increasing cystic fibrosis transmembrane conductance regulator open probability PLoS One 8 2013 e81589
-
(2013)
PLoS One
, vol.8
-
-
Zhang, S.1
Blount, A.C.2
McNicholas, C.M.3
Skinner, D.F.4
Chestnut, M.5
Kappes, J.C.6
Sorscher, E.J.7
Woodworth, B.A.8
-
13
-
-
84979769205
-
Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice
-
B. Dhooghe, C. Bouckaert, A. Capron, P. Wallemacq, T. Leal, and S. Noel Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice Biol. Open 2015
-
(2015)
Biol. Open
-
-
Dhooghe, B.1
Bouckaert, C.2
Capron, A.3
Wallemacq, P.4
Leal, T.5
Noel, S.6
-
14
-
-
61849109293
-
Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma
-
M. Lee, S. Kim, O.K. Kwon, S.R. Oh, H.K. Lee, and K. Ahn Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma Int. Immunopharmacol. 9 2009 418 424
-
(2009)
Int. Immunopharmacol.
, vol.9
, pp. 418-424
-
-
Lee, M.1
Kim, S.2
Kwon, O.K.3
Oh, S.R.4
Lee, H.K.5
Ahn, K.6
-
15
-
-
0037248470
-
Absorption of three wine-related polyphenols in three different matrices by healthy subjects
-
D.M. Goldberg, J. Yan, and G.J. Soleas Absorption of three wine-related polyphenols in three different matrices by healthy subjects Clin. Biochem. 36 2003 79 87
-
(2003)
Clin. Biochem.
, vol.36
, pp. 79-87
-
-
Goldberg, D.M.1
Yan, J.2
Soleas, G.J.3
-
16
-
-
78851469101
-
Bioavailability of resveratrol
-
T. Walle Bioavailability of resveratrol Ann. N. Y. Acad. Sci. 1215 2011 9 15
-
(2011)
Ann. N. Y. Acad. Sci.
, vol.1215
, pp. 9-15
-
-
Walle, T.1
-
17
-
-
9444296057
-
High absorption but very low bioavailability of oral resveratrol in humans
-
T. Walle, F. Hsieh, M.H. DeLegge, J.E. Oatis Jr., and U.K. Walle High absorption but very low bioavailability of oral resveratrol in humans Drug Metab. Dispos. Biol. Fate Chem. 32 2004 1377 1382
-
(2004)
Drug Metab. Dispos. Biol. Fate Chem.
, vol.32
, pp. 1377-1382
-
-
Walle, T.1
Hsieh, F.2
DeLegge, M.H.3
Oatis, J.E.4
Walle, U.K.5
-
18
-
-
0036345042
-
Trans-resveratrol oral administration does not affect the enzymatic activities in rat small intestine
-
M.E. Juan, and J.M. Planas Trans-resveratrol oral administration does not affect the enzymatic activities in rat small intestine J. Physiol. Biochem. 58 2002 59 60
-
(2002)
J. Physiol. Biochem.
, vol.58
, pp. 59-60
-
-
Juan, M.E.1
Planas, J.M.2
-
19
-
-
0036170178
-
The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful
-
M.E. Juan, M.P. Vinardell, and J.M. Planas The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful J. Nutr. 132 2002 257 260
-
(2002)
J. Nutr.
, vol.132
, pp. 257-260
-
-
Juan, M.E.1
Vinardell, M.P.2
Planas, J.M.3
-
20
-
-
77954848597
-
Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds
-
K. Bisht, K.H. Wagner, and A.C. Bulmer Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds Toxicology 278 2010 88 100
-
(2010)
Toxicology
, vol.278
, pp. 88-100
-
-
Bisht, K.1
Wagner, K.H.2
Bulmer, A.C.3
-
21
-
-
0034660659
-
Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation
-
S.K. Manna, A. Mukhopadhyay, and B.B. Aggarwal Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation J. Immunol. 164 2000 6509 6519
-
(2000)
J. Immunol.
, vol.164
, pp. 6509-6519
-
-
Manna, S.K.1
Mukhopadhyay, A.2
Aggarwal, B.B.3
-
23
-
-
84901398808
-
VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface
-
P.D. Eckford, M. Ramjeesingh, S. Molinski, S. Pasyk, J.F. Dekkers, C. Li, S. Ahmadi, W. Ip, T.E. Chung, K. Du, H. Yeger, J. Beekman, T. Gonska, and C.E. Bear VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface Chem. Biol. 21 2014 666 678
-
(2014)
Chem. Biol.
, vol.21
, pp. 666-678
-
-
Eckford, P.D.1
Ramjeesingh, M.2
Molinski, S.3
Pasyk, S.4
Dekkers, J.F.5
Li, C.6
Ahmadi, S.7
Ip, W.8
Chung, T.E.9
Du, K.10
Yeger, H.11
Beekman, J.12
Gonska, T.13
Bear, C.E.14
-
24
-
-
0038363377
-
A mutation in the cystic fibrosis transmembrane conductance regulator generates a novel internalization sequence and enhances endocytic rates
-
M.R. Silvis, J.A. Picciano, C. Bertrand, K. Weixel, R.J. Bridges, and N.A. Bradbury A mutation in the cystic fibrosis transmembrane conductance regulator generates a novel internalization sequence and enhances endocytic rates J. Biol. Chem. 278 2003 11554 11560
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11554-11560
-
-
Silvis, M.R.1
Picciano, J.A.2
Bertrand, C.3
Weixel, K.4
Bridges, R.J.5
Bradbury, N.A.6
-
26
-
-
0026521682
-
T84 cells: Anion selectivity demonstrates expression of Cl-conductance affected in cystic fibrosis
-
C.L. Bell, and P.M. Quinton T84 cells: anion selectivity demonstrates expression of Cl-conductance affected in cystic fibrosis Am. J. Phys. 262 1992 C555 C562
-
(1992)
Am. J. Phys.
, vol.262
, pp. C555-C562
-
-
Bell, C.L.1
Quinton, P.M.2
-
27
-
-
0026654011
-
Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents
-
J.A. Wagner, T.V. McDonald, P.T. Nghiem, A.W. Lowe, H. Schulman, D.C. Gruenert, L. Stryer, and P. Gardner Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents Proc. Natl. Acad. Sci. U. S. A. 89 1992 6785 6789
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 6785-6789
-
-
Wagner, J.A.1
McDonald, T.V.2
Nghiem, P.T.3
Lowe, A.W.4
Schulman, H.5
Gruenert, D.C.6
Stryer, L.7
Gardner, P.8
-
28
-
-
0032418043
-
An improved method to obtain highly differentiated monolayers of human bronchial epithelial cells
-
L.J. Galietta, S. Lantero, A. Gazzolo, O. Sacco, L. Romano, G.A. Rossi, and O. Zegarra-Moran An improved method to obtain highly differentiated monolayers of human bronchial epithelial cells In Vitro Cell. Dev. Biol. Anim. 34 1998 478 481
-
(1998)
In Vitro Cell. Dev. Biol. Anim.
, vol.34
, pp. 478-481
-
-
Galietta, L.J.1
Lantero, S.2
Gazzolo, A.3
Sacco, O.4
Romano, L.5
Rossi, G.A.6
Zegarra-Moran, O.7
-
29
-
-
73249114731
-
Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770
-
F. Van Goor, S. Hadida, P.D. Grootenhuis, B. Burton, D. Cao, T. Neuberger, A. Turnbull, A. Singh, J. Joubran, A. Hazlewood, J. Zhou, J. McCartney, V. Arumugam, C. Decker, J. Yang, C. Young, E.R. Olson, J.J. Wine, R.A. Frizzell, M. Ashlock, and P. Negulescu Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770 Proc. Natl. Acad. Sci. U. S. A. 106 2009 18825 18830
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 18825-18830
-
-
Van Goor, F.1
Hadida, S.2
Grootenhuis, P.D.3
Burton, B.4
Cao, D.5
Neuberger, T.6
Turnbull, A.7
Singh, A.8
Joubran, J.9
Hazlewood, A.10
Zhou, J.11
McCartney, J.12
Arumugam, V.13
Decker, C.14
Yang, J.15
Young, C.16
Olson, E.R.17
Wine, J.J.18
Frizzell, R.A.19
Ashlock, M.20
Negulescu, P.21
more..
-
30
-
-
0031867156
-
Characterization of PKA isoforms and kinase-dependent activation of chloride secretion in T84 cells
-
A.K. Singh, K. Tasken, W. Walker, R. Frizzell, S.C. Watkins, R.J. Bridges, and N.A. Bradbury Characterization of PKA isoforms and kinase-dependent activation of chloride secretion in T84 cells Am. J. Phys. 275 1998 C562 C570
-
(1998)
Am. J. Phys.
, vol.275
, pp. C562-C570
-
-
Singh, A.K.1
Tasken, K.2
Walker, W.3
Frizzell, R.4
Watkins, S.C.5
Bridges, R.J.6
Bradbury, N.A.7
-
31
-
-
84863011114
-
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases
-
S.J. Park, F. Ahmad, A. Philp, K. Baar, T. Williams, H. Luo, H. Ke, H. Rehmann, R. Taussig, A.L. Brown, M.K. Kim, M.A. Beaven, A.B. Burgin, V. Manganiello, and J.H. Chung Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases Cell 148 2012 421 433
-
(2012)
Cell
, vol.148
, pp. 421-433
-
-
Park, S.J.1
Ahmad, F.2
Philp, A.3
Baar, K.4
Williams, T.5
Luo, H.6
Ke, H.7
Rehmann, H.8
Taussig, R.9
Brown, A.L.10
Kim, M.K.11
Beaven, M.A.12
Burgin, A.B.13
Manganiello, V.14
Chung, J.H.15
-
32
-
-
11144355340
-
Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects
-
M.E. Egan, M. Pearson, S.A. Weiner, V. Rajendran, D. Rubin, J. Glockner-Pagel, S. Canny, K. Du, G.L. Lukacs, and M.J. Caplan Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects Science 304 2004 600 602
-
(2004)
Science
, vol.304
, pp. 600-602
-
-
Egan, M.E.1
Pearson, M.2
Weiner, S.A.3
Rajendran, V.4
Rubin, D.5
Glockner-Pagel, J.6
Canny, S.7
Du, K.8
Lukacs, G.L.9
Caplan, M.J.10
-
33
-
-
38349033879
-
Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator
-
A. Schmidt, L.K. Hughes, Z. Cai, F. Mendes, H. Li, D.N. Sheppard, and M.D. Amaral Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator Br. J. Pharmacol. 153 2008 1311 1323
-
(2008)
Br. J. Pharmacol.
, vol.153
, pp. 1311-1323
-
-
Schmidt, A.1
Hughes, L.K.2
Cai, Z.3
Mendes, F.4
Li, H.5
Sheppard, D.N.6
Amaral, M.D.7
-
35
-
-
4644360693
-
Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models
-
Y. Song, N.D. Sonawane, D. Salinas, L. Qian, N. Pedemonte, L.J. Galietta, and A.S. Verkman Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models J. Biol. Chem. 279 2004 40629 40633
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40629-40633
-
-
Song, Y.1
Sonawane, N.D.2
Salinas, D.3
Qian, L.4
Pedemonte, N.5
Galietta, L.J.6
Verkman, A.S.7
-
37
-
-
84862180074
-
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor
-
A.A. Qureshi, X.Q. Guan, J.C. Reis, C.J. Papasian, S. Jabre, D.C. Morrison, and N. Qureshi Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor Lipids Health Dis. 11 2012 76
-
(2012)
Lipids Health Dis.
, vol.11
, pp. 76
-
-
Qureshi, A.A.1
Guan, X.Q.2
Reis, J.C.3
Papasian, C.J.4
Jabre, S.5
Morrison, D.C.6
Qureshi, N.7
-
38
-
-
0025337617
-
A cystic fibrosis pancreatic adenocarcinoma cell line
-
R.A. Schoumacher, J. Ram, M.C. Iannuzzi, N.A. Bradbury, R.W. Wallace, C.T. Hon, D.R. Kelly, S.M. Schmid, F.B. Gelder, T.A. Rado, and et al. A cystic fibrosis pancreatic adenocarcinoma cell line Proc. Natl. Acad. Sci. U. S. A. 87 1990 4012 4016
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 4012-4016
-
-
Schoumacher, R.A.1
Ram, J.2
Iannuzzi, M.C.3
Bradbury, N.A.4
Wallace, R.W.5
Hon, C.T.6
Kelly, D.R.7
Schmid, S.M.8
Gelder, F.B.9
Rado, T.A.10
-
39
-
-
84883297845
-
Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression
-
P. Liu, H. Liang, Q. Xia, P. Li, H. Kong, P. Lei, S. Wang, and Z. Tu Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression Clin. Transl. Oncol. 15 2013 741 746
-
(2013)
Clin. Transl. Oncol.
, vol.15
, pp. 741-746
-
-
Liu, P.1
Liang, H.2
Xia, Q.3
Li, P.4
Kong, H.5
Lei, P.6
Wang, S.7
Tu, Z.8
-
40
-
-
76349114046
-
Antagonism of beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1
-
N.C. Chang, M. Nguyen, M. Germain, and G.C. Shore Antagonism of beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1 EMBO J. 29 2010 606 618
-
(2010)
EMBO J.
, vol.29
, pp. 606-618
-
-
Chang, N.C.1
Nguyen, M.2
Germain, M.3
Shore, G.C.4
-
41
-
-
76349098949
-
Crosstalk between apoptosis and autophagy within the beclin 1 interactome
-
M.C. Maiuri, A. Criollo, and G. Kroemer Crosstalk between apoptosis and autophagy within the beclin 1 interactome EMBO J. 29 2010 515 516
-
(2010)
EMBO J.
, vol.29
, pp. 515-516
-
-
Maiuri, M.C.1
Criollo, A.2
Kroemer, G.3
-
42
-
-
80052714034
-
BH3 mimetics activate multiple pro-autophagic pathways
-
S.A. Malik, I. Orhon, E. Morselli, A. Criollo, S. Shen, G. Marino, A. BenYounes, P. Benit, P. Rustin, M.C. Maiuri, and G. Kroemer BH3 mimetics activate multiple pro-autophagic pathways Oncogene 30 2011 3918 3929
-
(2011)
Oncogene
, vol.30
, pp. 3918-3929
-
-
Malik, S.A.1
Orhon, I.2
Morselli, E.3
Criollo, A.4
Shen, S.5
Marino, G.6
BenYounes, A.7
Benit, P.8
Rustin, P.9
Maiuri, M.C.10
Kroemer, G.11
-
43
-
-
84888988441
-
Potentiation of mutant CFTR Cl- channel currents by the naturally occurring stilbene compound resveratrol
-
B. Yu, Y. Zhang, Y. Sui, S. Yang, J. Luan, X. Wang, T. Ma, and H. Yang Potentiation of mutant CFTR Cl- channel currents by the naturally occurring stilbene compound resveratrol Pharmazie 68 2013 877 881
-
(2013)
Pharmazie
, vol.68
, pp. 877-881
-
-
Yu, B.1
Zhang, Y.2
Sui, Y.3
Yang, S.4
Luan, J.5
Wang, X.6
Ma, T.7
Yang, H.8
-
44
-
-
84866986070
-
Proteasome protease mediated regulation of cytokine induction and inflammation
-
N. Qureshi, D.C. Morrison, and J. Reis Proteasome protease mediated regulation of cytokine induction and inflammation Biochim. Biophys. Acta 1823 2012 2087 2093
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 2087-2093
-
-
Qureshi, N.1
Morrison, D.C.2
Reis, J.3
-
45
-
-
0033917142
-
Defects in processing and trafficking of the cystic fibrosis transmembrane conductance regulator
-
W.R. Skach Defects in processing and trafficking of the cystic fibrosis transmembrane conductance regulator Kidney Int. 57 2000 825 831
-
(2000)
Kidney Int.
, vol.57
, pp. 825-831
-
-
Skach, W.R.1
-
46
-
-
84871352589
-
Rescue of murine F508del CFTR activity in native intestine by low temperature and proteasome inhibitors
-
M. Wilke, A. Bot, H. Jorna, B.J. Scholte, and H.R. de Jonge Rescue of murine F508del CFTR activity in native intestine by low temperature and proteasome inhibitors PLoS One 7 2012 e52070
-
(2012)
PLoS One
, vol.7
-
-
Wilke, M.1
Bot, A.2
Jorna, H.3
Scholte, B.J.4
De Jonge, H.R.5
-
47
-
-
77956238947
-
C-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cells
-
S. Ye, K. Cihil, D.B. Stolz, J.M. Pilewski, B.A. Stanton, and A. Swiatecka-Urban c-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cells J. Biol. Chem. 285 2010 27008 27018
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27008-27018
-
-
Ye, S.1
Cihil, K.2
Stolz, D.B.3
Pilewski, J.M.4
Stanton, B.A.5
Swiatecka-Urban, A.6
-
48
-
-
77955607650
-
Peripheral protein quality control removes unfolded CFTR from the plasma membrane
-
T. Okiyoneda, H. Barriere, M. Bagdany, W.M. Rabeh, K. Du, J. Hohfeld, J.C. Young, and G.L. Lukacs Peripheral protein quality control removes unfolded CFTR from the plasma membrane Science 329 2010 805 810
-
(2010)
Science
, vol.329
, pp. 805-810
-
-
Okiyoneda, T.1
Barriere, H.2
Bagdany, M.3
Rabeh, W.M.4
Du, K.5
Hohfeld, J.6
Young, J.C.7
Lukacs, G.L.8
-
49
-
-
0038309561
-
Resveratrol activates adenylyl-cyclase in human breast cancer cells: A novel, estrogen receptor-independent cytostatic mechanism
-
A.M. El-Mowafy, and M. Alkhalaf Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism Carcinogenesis 24 2003 869 873
-
(2003)
Carcinogenesis
, vol.24
, pp. 869-873
-
-
El-Mowafy, A.M.1
Alkhalaf, M.2
-
50
-
-
65949114049
-
Resveratrol inhibits foam cell formation via NADPH oxidase 1-mediated reactive oxygen species and monocyte chemotactic protein-1
-
D.W. Park, K. Baek, J.R. Kim, J.J. Lee, S.H. Ryu, B.R. Chin, and S.H. Baek Resveratrol inhibits foam cell formation via NADPH oxidase 1-mediated reactive oxygen species and monocyte chemotactic protein-1 Exp. Mol. Med. 41 2009 171 179
-
(2009)
Exp. Mol. Med.
, vol.41
, pp. 171-179
-
-
Park, D.W.1
Baek, K.2
Kim, J.R.3
Lee, J.J.4
Ryu, S.H.5
Chin, B.R.6
Baek, S.H.7
-
51
-
-
0029806827
-
Enhancer stimulation unmasks latent gene transfer after adenovirus-mediated gene delivery into human vascular smooth muscle cells
-
G.J. Clesham, H. Browne, S. Efstathiou, and P.L. Weissberg Enhancer stimulation unmasks latent gene transfer after adenovirus-mediated gene delivery into human vascular smooth muscle cells Circ. Res. 79 1996 1188 1195
-
(1996)
Circ. Res.
, vol.79
, pp. 1188-1195
-
-
Clesham, G.J.1
Browne, H.2
Efstathiou, S.3
Weissberg, P.L.4
-
52
-
-
0028866431
-
Transcription of cystic fibrosis transmembrane conductance regulator requires a CCAAT-like element for both basal and cAMP-mediated regulation
-
N. Pittman, G. Shue, N.S. LeLeiko, and M.J. Walsh Transcription of cystic fibrosis transmembrane conductance regulator requires a CCAAT-like element for both basal and cAMP-mediated regulation J. Biol. Chem. 270 1995 28848 28857
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28848-28857
-
-
Pittman, N.1
Shue, G.2
LeLeiko, N.S.3
Walsh, M.J.4
-
53
-
-
0032576605
-
Aggresomes: A cellular response to misfolded proteins
-
J.A. Johnston, C.L. Ward, and R.R. Kopito Aggresomes: a cellular response to misfolded proteins J. Cell Biol. 143 1998 1883 1898
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1883-1898
-
-
Johnston, J.A.1
Ward, C.L.2
Kopito, R.R.3
-
54
-
-
84928494186
-
DeltaF508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments
-
L. Fu, A. Rab, L. Tang, Z. Bebok, S.M. Rowe, R. Bartoszewski, and J.F. Collawn DeltaF508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments PLoS One 10 2015 e0123131
-
(2015)
PLoS One
, vol.10
-
-
Fu, L.1
Rab, A.2
Tang, L.3
Bebok, Z.4
Rowe, S.M.5
Bartoszewski, R.6
Collawn, J.F.7
-
55
-
-
84924063047
-
Synonymous codon usage affects the expression of wild type and F508del CFTR
-
K. Shah, Y. Cheng, B. Hahn, R. Bridges, N.A. Bradbury, and D.M. Mueller Synonymous codon usage affects the expression of wild type and F508del CFTR J. Mol. Biol. 2015
-
(2015)
J. Mol. Biol.
-
-
Shah, K.1
Cheng, Y.2
Hahn, B.3
Bridges, R.4
Bradbury, N.A.5
Mueller, D.M.6
-
56
-
-
0023747610
-
Isoproterenol-induced desensitization of mucin release in isolated rat submandibular acini
-
N.A. Bradbury, and M.A. McPherson Isoproterenol-induced desensitization of mucin release in isolated rat submandibular acini Biochim. Biophys. Acta 970 1988 363 370
-
(1988)
Biochim. Biophys. Acta
, vol.970
, pp. 363-370
-
-
Bradbury, N.A.1
McPherson, M.A.2
-
57
-
-
84899423417
-
Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from Chinese medicinal plants
-
Y. Zhang, B. Yu, Y. Sui, X. Gao, H. Yang, and T. Ma Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from Chinese medicinal plants PLoS One 9 2014 e94302
-
(2014)
PLoS One
, vol.9
-
-
Zhang, Y.1
Yu, B.2
Sui, Y.3
Gao, X.4
Yang, H.5
Ma, T.6
-
58
-
-
84907223425
-
Potentiator ivacaftor abrogates pharmacological correction of DeltaF508 CFTR in cystic fibrosis
-
(246ra296)
-
D.M. Cholon, N.L. Quinney, M.L. Fulcher, C.R. Esther Jr., J. Das, N.V. Dokholyan, S.H. Randell, R.C. Boucher, and M. Gentzsch Potentiator ivacaftor abrogates pharmacological correction of DeltaF508 CFTR in cystic fibrosis Sci. Transl. Med. 6 2014 (246ra296)
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Cholon, D.M.1
Quinney, N.L.2
Fulcher, M.L.3
Esther, C.R.4
Das, J.5
Dokholyan, N.V.6
Randell, S.H.7
Boucher, R.C.8
Gentzsch, M.9
-
59
-
-
0022973473
-
Na + transport in cystic fibrosis respiratory epithelia
-
R.C. Boucher, M.J. Stutts, M.R. Knowles, L. Cantley, and J.T. Gatzy Na + transport in cystic fibrosis respiratory epithelia Abnorm. Basal Rate Response Adenylate Cyclase Activation J. Clin. Invest. 78 1986 1245 1252
-
(1986)
Abnorm. Basal Rate Response Adenylate Cyclase Activation J. Clin. Invest.
, vol.78
, pp. 1245-1252
-
-
Boucher, R.C.1
Stutts, M.J.2
Knowles, M.R.3
Cantley, L.4
Gatzy, J.T.5
-
60
-
-
0029080413
-
Relative expression of the human epithelial Na + channel subunits in normal and cystic fibrosis airways
-
L.H. Burch, C.R. Talbot, M.R. Knowles, C.M. Canessa, B.C. Rossier, and R.C. Boucher Relative expression of the human epithelial Na + channel subunits in normal and cystic fibrosis airways Am. J. Phys. 269 1995 C511 C518
-
(1995)
Am. J. Phys.
, vol.269
, pp. C511-C518
-
-
Burch, L.H.1
Talbot, C.R.2
Knowles, M.R.3
Canessa, C.M.4
Rossier, B.C.5
Boucher, R.C.6
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