Electric fields and enzyme catalysis

Annual Review of Biochemistry

Volumn 86, Issue , 2017, Pages 387-415

  Fried, Stephen D ^a   Boxer, Steven G ^b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Electric fields; Enzyme electrostatics; Infrared spectroscopy; Preorganization; Protein biophysics; Vibrational Stark effect

Indexed keywords

CARBONYL DERIVATIVE; ENZYME; ISOMERASE; OXOSTEROID; SOLVENT; 4-CHLOROBENZOYL COENZYME A DEHALOGENASE; BACTERIAL PROTEIN; HYDROLASE; STEROID DELTA ISOMERASE;

CATALYSIS; CHEMICAL REACTION; DIPOLE; ELECTRIC FIELD; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYMOLOGY; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SPECTROSCOPY; STARK SPECTROSCOPY; STATIC ELECTRICITY; BIOCATALYSIS; CHEMICAL MODEL; CHEMISTRY; GENE EXPRESSION; GENETICS; INFRARED SPECTROPHOTOMETRY; KINETICS; METABOLISM; MUTATION; PROCEDURES; PSEUDOMONAS; THERMODYNAMICS;

BACTERIAL PROTEINS; BIOCATALYSIS; CATALYTIC DOMAIN; GENE EXPRESSION; HYDROLASES; KETOSTEROIDS; KINETICS; MODELS, CHEMICAL; MOLECULAR DYNAMICS SIMULATION; MUTATION; PSEUDOMONAS; SPECTROPHOTOMETRY, INFRARED; STATIC ELECTRICITY; STEROID ISOMERASES; THERMODYNAMICS;

EID: 84987861629     PISSN: 00664154     EISSN: 15454509     Source Type: Book Series    
DOI: 10.1146/annurev-biochem-061516-044432     Document Type: Review

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