Contributions of long-range electrostatic interactions to 4-chlorobenzoyl-CoA dehalogenase catalysis: A combined theoretical and experimental study

Biochemistry

Volumn 45, Issue 1, 2006, Pages 102-112

  Wu, Jingbo ^a   Xu, Dingguo ^a   Lu, Xuefeng ^a   Wang, Canhui ^a   Guo, Hua ^a   Dunaway Mariano, Debra ^a  

^a UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLATION; CATALYSIS; DEHALOGENATION; ELECTROSTATIC ACCELERATORS; ENZYMES; POLARIZATION;

ELECTRON POLARIZATION; ELECTROSTATIC INTERACTIONS; ENZYME CATALYSIS;

GENETIC ENGINEERING;

4 CHLOROBENZOYL COENZYME A DEHALOGENASE; 4 METHYLBENZOYL COENZYME A; CARBOXYLIC ACID; COENZYME A; ENZYME; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CATALYSIS; COMPLEX FORMATION; ELECTRICITY; ENERGY; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; EXPERIMENTAL STUDY; LIGAND BINDING; MOLECULAR INTERACTION; MUTANT; POLARIZATION; PRIORITY JOURNAL; QUANTUM MECHANICS; THEORETICAL MODEL; THEORETICAL STUDY; ULTRAVIOLET SPECTROSCOPY; WILD TYPE;

AMINO ACID SUBSTITUTION; AMINO ACIDS, AROMATIC; ASPARTIC ACID; CATALYSIS; ELECTROSTATICS; GLUTAMINE; HYDROLASES; LIGANDS; MODELS, CHEMICAL; MUTATION; QUANTUM THEORY; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TIME FACTORS;

EID: 30144432502     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051477w     Document Type: Article

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