Characterizing the complexity of enzymes on the basis of their mechanisms and structures with a bio-computational analysis

FEBS Journal

Volumn 278, Issue 20, 2011, Pages 3835-3845

  Holliday, Gemma L ^a   Fischer, Julia D ^a   Mitchell, John B O ^b   Thornton, Janet M ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

active sites; catalysis; enzyme; evolution; MACiE; mechanism; specificity; structure

Indexed keywords

AMINO ACID; CARBON MONOXIDE DEHYDROGENASE; CYTOCHROME C OXIDASE; GLUTAMINE FRUCTOSE 6 PHOSPHATE AMINOTRANSFERASE; HALOPEROXIDASE; METAL ION; PEROXIDASE; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE; TRYPTASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; BIOLOGICAL ACTIVITY; COMPLEX FORMATION; CONFERENCE PAPER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MATHEMATICAL COMPUTING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; SEQUENCE ANALYSIS;

AMINO ACIDS; ANIMALS; CATALYTIC DOMAIN; COENZYMES; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; ENZYMES; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE;

EID: 80053616941     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08190.x     Document Type: Conference Paper

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