Electrostatic stress in catalysis: Structure and mechanism of the enzyme orotidine monophosphate decarboxylase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 5, 2000, Pages 2017-2022

  Wu, Ning ^a,b,c   Mo, Yirong ^d   Gao, Jiali ^d,e   Pai, Emil F ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d UNIVERSITY AT BUFFALO   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZAURIDINE; DECARBOXYLASE INHIBITOR; OROTIDINE 5' PHOSPHATE DECARBOXYLASE; RIBOSE PHOSPHATE; URIDINE PHOSPHATE;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME INHIBITOR INTERACTION; ENZYME MECHANISM; ENZYME STRUCTURE; METHANOBACTERIUM THERMOAUTOTROPHICUM; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PYRIMIDINE SYNTHESIS; QUANTUM MECHANICS; SURFACE CHARGE;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; METHANOBACTERIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OROTIDINE-5'-PHOSPHATE DECARBOXYLASE; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS;

BACTERIA (MICROORGANISMS); METHANOBACTERIUM; METHANOTHERMOBACTER THERMAUTOTROPHICUS;

EID: 0034102419     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.050417797     Document Type: Article

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