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Volumn 17, Issue 9, 2016, Pages

Sanguinaria canadensis: Traditional medicine, phytochemical composition, biological activities and current uses

Author keywords

Alkaloid; Black salve; Bloodroot; Escharotic; Herbal; Sanguinaria canadensis; Sanguinarine; Skin cancer

Indexed keywords

ALKALOID; ALLOCRYPTOPINE; BENZOPHENANTHRIDINE DERIVATIVE; CHELERYTHRINE; CHELILUTINE; CHELIRUBINE; PLANT EXTRACT; PROTOPINE; SANGUILUTINE; SANGUINARIA CANADENSIS EXTRACT; SANGUINARINE; SANGUIRUBINE; UNCLASSIFIED DRUG; ZEEL; ANTINEOPLASTIC AGENT;

EID: 84984846134     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms17091414     Document Type: Review
Times cited : (78)

References (296)
  • 1
    • 0035044430 scopus 로고    scopus 로고
    • The value of plants used in traditional medicine for drug discovery
    • Fabricant, D.S.; Farnsworth, N.R. The value of plants used in traditional medicine for drug discovery. Environ. Health Perspect. 2001, 109, 69-75
    • (2001) Environ. Health Perspect , vol.109 , pp. 69-75
    • Fabricant, D.S.1    Farnsworth, N.R.2
  • 2
    • 0003607808 scopus 로고    scopus 로고
    • University of Oklahoma Press: Norman, OK, USA
    • Vogel, V.J. American Indian Medicine; University of Oklahoma Press: Norman, OK, USA, 2013.
    • (2013) American Indian Medicine
    • Vogel, V.J.1
  • 3
    • 61449151891 scopus 로고    scopus 로고
    • In vitro screening for the tumoricidal properties of international medicinal herbs
    • Mazzio, E.A.; Soliman, K.F. In vitro screening for the tumoricidal properties of international medicinal herbs. Phytother. Res. 2009, 23, 385-398
    • (2009) Phytother. Res , vol.23 , pp. 385-398
    • Mazzio, E.A.1    Soliman, K.F.2
  • 4
    • 0000791234 scopus 로고
    • Alkaloide der mohngewächse (Papaveraceae) XVII. Über neue alkaloide aus Sanguinaria canadensis L. Collect
    • Slavik, J.; Slavikova, L. Alkaloide der mohngewächse (papaveraceae) XVII. Über neue alkaloide aus Sanguinaria canadensis L. Collect. Czechoslov. Chem. Commun. 1960, 25, 1667-1675
    • (1960) Czechoslov. Chem. Commun , vol.25 , pp. 1667-1675
    • Slavik, J.1    Slavikova, L.2
  • 5
    • 0036731137 scopus 로고    scopus 로고
    • White patch of maxillary vestibule. Sanguinarine-associated leukoplakia
    • Damm, D.D.; Fantasia, J.E. White patch of maxillary vestibule. Sanguinarine-associated leukoplakia. Gen. Dent. 2002, 50, 466
    • (2002) Gen. Dent , vol.50
    • Damm, D.D.1    Fantasia, J.E.2
  • 11
    • 0031788303 scopus 로고    scopus 로고
    • Modes of action of allelochemical alkaloids: Interaction with neuroreceptors, DNA, and other molecular targets
    • Wink, M.; Schmeller, T.; Latz-Bruning, B. Modes of action of allelochemical alkaloids: Interaction with neuroreceptors, DNA, and other molecular targets. J. Chem. Ecol. 1998, 24, 1881-1937
    • (1998) J. Chem. Ecol , vol.24 , pp. 1881-1937
    • Wink, M.1    Schmeller, T.2    Latz-Bruning, B.3
  • 12
    • 0031191960 scopus 로고    scopus 로고
    • Anti-thrombotic and anti-inflammatory activities of protopine
    • Saeed, S.; Gilani, A.; Majoo, R.; Shah, B. Anti-thrombotic and anti-inflammatory activities of protopine. Pharmacol. Res. 1997, 36, 1-7
    • (1997) Pharmacol. Res , vol.36 , pp. 1-7
    • Saeed, S.1    Gilani, A.2    Majoo, R.3    Shah, B.4
  • 14
    • 0024730953 scopus 로고
    • Long-term clinical evaluation of toothpaste and oral rinse containing sanguinaria extract in controlling plaque, gingival inflammation, and sulcular bleeding during orthodontic treatment
    • Hannah, J.J.; Johnson, J.D.; Kuftinec, M.M. Long-term clinical evaluation of toothpaste and oral rinse containing sanguinaria extract in controlling plaque, gingival inflammation, and sulcular bleeding during orthodontic treatment. Am. J. Orthod. Dentofac. Orthop. 1989, 96, 199-207
    • (1989) Am. J. Orthod. Dentofac. Orthop , vol.96 , pp. 199-207
    • Hannah, J.J.1    Johnson, J.D.2    Kuftinec, M.M.3
  • 15
    • 1942486355 scopus 로고    scopus 로고
    • Dual inhibition of 5-lipoxygenase/cyclooxygenase by a reconstituted homeopathic remedy; possible explanation for clinical efficacy and favourable gastrointestinal tolerability
    • Jäggi, R.; Würgler, U.; Grandjean, F.; Weiser, M. Dual inhibition of 5-lipoxygenase/cyclooxygenase by a reconstituted homeopathic remedy; possible explanation for clinical efficacy and favourable gastrointestinal tolerability. Inflamm. Res. 2004, 53, 150-157
    • (2004) Inflamm. Res , vol.53 , pp. 150-157
    • Jäggi, R.1    Würgler, U.2    Grandjean, F.3    Weiser, M.4
  • 16
    • 84941082807 scopus 로고    scopus 로고
    • Black salve and bloodroot extract in dermatologic conditions
    • Hou, J.L.; Brewer, J.D. Black salve and bloodroot extract in dermatologic conditions. Cutis 2015, 95, 309-311
    • (2015) Cutis , vol.95 , pp. 309-311
    • Hou, J.L.1    Brewer, J.D.2
  • 17
    • 84867330414 scopus 로고    scopus 로고
    • Rise and fall of oral health products with canadian bloodroot extract
    • Vlachojannis, C.; Magora, F.; Chrubasik, S. Rise and fall of oral health products with canadian bloodroot extract. Phytother. Res. 2012, 26, 1423-1426
    • (2012) Phytother. Res , vol.26 , pp. 1423-1426
    • Vlachojannis, C.1    Magora, F.2    Chrubasik, S.3
  • 19
    • 47049110088 scopus 로고    scopus 로고
    • Death from metastatic basal cell carcinoma: Herbal remedy or just unlucky
    • Laub, D.R., Jr. Death from metastatic basal cell carcinoma: Herbal remedy or just unlucky? J. Plast. Reconstr. Aesth. Surg. 2008, 61, 846-848
    • (2008) J. Plast. Reconstr. Aesth. Surg , vol.61 , pp. 846-848
    • Laub, D.R.1
  • 20
    • 0034861639 scopus 로고    scopus 로고
    • Environmental and genotypic influences on isoquinoline alkaloid content in Sanguinaria canadensis
    • Salmore, A.K.; Hunter, M.D. Environmental and genotypic influences on isoquinoline alkaloid content in Sanguinaria canadensis. J. Chem. Ecol. 2001, 27, 1729-1747
    • (2001) J. Chem. Ecol , vol.27 , pp. 1729-1747
    • Salmore, A.K.1    Hunter, M.D.2
  • 21
    • 0004138082 scopus 로고
    • Geographic variation in alkaloid content of Sanguinaria canadensis (Papaveraceae)
    • Bennett, B.C.; Bell, C.R.; Boulware, R.T. Geographic variation in alkaloid content of Sanguinaria canadensis (Papaveraceae). Rhodora 1990, 92, 57-69.
    • (1990) Rhodora , vol.92 , pp. 57-69
    • Bennett, B.C.1    Bell, C.R.2    Boulware, R.T.3
  • 23
    • 67651122937 scopus 로고    scopus 로고
    • Bloodroot (Sanguinaria canadensis L., papaveraceae) enhances proliferation and cytokine production by human peripheral blood mononuclear cells in an in vitro model
    • Senchina, D.S.; Flinn, G.N.; McCann, D.A.; Kohut, M.L.; Shearn, C.T. Bloodroot (Sanguinaria canadensis L., papaveraceae) enhances proliferation and cytokine production by human peripheral blood mononuclear cells in an in vitro model. J. Herbs Spices Med. Plants 2009, 15, 45-65
    • (2009) J. Herbs Spices Med. Plants , vol.15 , pp. 45-65
    • Senchina, D.S.1    Flinn, G.N.2    McCann, D.A.3    Kohut, M.L.4    Shearn, C.T.5
  • 24
    • 0037713603 scopus 로고    scopus 로고
    • Sanguinarine-induced apoptosis is associated with an early and severe cellular glutathione depletion
    • Debiton, E.; Madelmont, J.C.; Legault, J.; Barthomeuf, C. Sanguinarine-induced apoptosis is associated with an early and severe cellular glutathione depletion. Cancer Chemother. Pharmacol. 2003, 51, 474-482
    • (2003) Cancer Chemother. Pharmacol , vol.51 , pp. 474-482
    • Debiton, E.1    Madelmont, J.C.2    Legault, J.3    Barthomeuf, C.4
  • 25
    • 21344452114 scopus 로고    scopus 로고
    • Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues
    • Karp, J.M.; Rodrigo, K.A.; Pei, P.; Pavlick, M.D.; Andersen, J.D.; McTigue, D.J.; Fields, H.W.; Mallery, S.R. Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues. Toxicol. Lett. 2005, 158, 50-60
    • (2005) Toxicol. Lett , vol.158 , pp. 50-60
    • Karp, J.M.1    Rodrigo, K.A.2    Pei, P.3    Pavlick, M.D.4    Andersen, J.D.5    McTigue, D.J.6    Fields, H.W.7    Mallery, S.R.8
  • 27
    • 0041176645 scopus 로고
    • The genera of papaveraceae and fumariaceae in the Southeastern United States
    • Ernst, W.R. The genera of papaveraceae and fumariaceae in the Southeastern United States. J. Arnold Arbor. 1962, 43, 315-343.
    • (1962) J. Arnold Arbor , vol.43 , pp. 315-343
    • Ernst, W.R.1
  • 28
    • 84984835527 scopus 로고
    • Notes on the seedlings of bloodroot
    • Nieuwland, J.A. Notes on the seedlings of bloodroot. Am. Midl. Nat. 1910, 1, 199-203
    • (1910) Am. Midl. Nat , vol.1 , pp. 199-203
    • Nieuwland, J.A.1
  • 30
    • 0004127210 scopus 로고
    • Sumptibus Auctoris: London, UK
    • Plukenet, L. Almagestum Botanicum; Sumptibus Auctoris: London, UK, 1696; pp. 279-280.
    • (1696) Almagestum Botanicum , pp. 279-280
    • Plukenet, L.1
  • 31
    • 84984844697 scopus 로고
    • Sanguinaria (U.S.P.)-Sanguinaria
    • Ohio Valley Co.: Cincinnatti, OH, USA
    • Felter, H.W.; Lloyd, J.U. Sanguinaria (u.S.P.)-Sanguinaria. In King’s American Dispensatory; Ohio Valley Co.: Cincinnatti, OH, USA, 1898; pp. 1708-1714.
    • (1898) King’s American Dispensatory , pp. 1708-1714
    • Felter, H.W.1    Lloyd, J.U.2
  • 33
    • 0003961610 scopus 로고    scopus 로고
    • Laurentii Salvii: Stockholm, Sweden
    • Linnaeus, C. Species Plantarum; Laurentii Salvii: Stockholm, Sweden, 1753; p.
    • Species Plantarum
    • Linnaeus, C.1
  • 35
    • 0001373007 scopus 로고
    • Bee pollination of facultatively xenogamous Sanguinaria canadensis L. Bull
    • Lyon, D.L. Bee pollination of facultatively xenogamous Sanguinaria canadensis L. Bull. Torrey Bot. Club 1992, 119, 368-375
    • (1992) Torrey Bot. Club , vol.119 , pp. 368-375
    • Lyon, D.L.1
  • 36
    • 0001280612 scopus 로고
    • The guild of myrmecochores in the herbaceous Flora of West Virginia forests
    • Beattie, A.J.; Culver, D.C. The guild of myrmecochores in the herbaceous Flora of West Virginia forests. Ecology 1981, 62, 107-115
    • (1981) Ecology , vol.62 , pp. 107-115
    • Beattie, A.J.1    Culver, D.C.2
  • 37
    • 34250259986 scopus 로고
    • Population consequences of changes in an ant-seed mutualism in Sanguinaria canadensis
    • Pudlo, R.J.; Beattie, A.J.; Culver, D.C. Population consequences of changes in an ant-seed mutualism in Sanguinaria canadensis. Oecologia 1980, 46, 32-37
    • (1980) Oecologia , vol.46 , pp. 32-37
    • Pudlo, R.J.1    Beattie, A.J.2    Culver, D.C.3
  • 38
    • 0031722316 scopus 로고    scopus 로고
    • Myrmecochorous dispersal distances: A world survey
    • Gomez, C.; Espadaler, X. Myrmecochorous dispersal distances: A world survey. J. Biogeogr. 1998, 25, 573-580
    • (1998) J. Biogeogr , vol.25 , pp. 573-580
    • Gomez, C.1    Espadaler, X.2
  • 39
    • 0004152831 scopus 로고
    • Influence of elaiosome removal on germination in five ant-dispersed plant species
    • Lobstein, M.B.; Rockwood, L.L. Influence of elaiosome removal on germination in five ant-dispersed plant species. Va. J. Sci. 1993, 44, 59-72.
    • (1993) Va. J. Sci , vol.44 , pp. 59-72
    • Lobstein, M.B.1    Rockwood, L.L.2
  • 40
    • 0025640731 scopus 로고
    • Invasion of polygyne fire ants decimates native ants and disrupts arthropod community
    • Porter, S.D.; Savignano, D.A. Invasion of polygyne fire ants decimates native ants and disrupts arthropod community. Ecology 1990, 71, 2095-2106
    • (1990) Ecology , vol.71 , pp. 2095-2106
    • Porter, S.D.1    Savignano, D.A.2
  • 41
    • 0034888762 scopus 로고    scopus 로고
    • Ant-seed mutualisms: Can red imported fire ants sour the relationship?
    • Zettler, J.A.; Spira, T.P.; Allen, C.R. Ant-seed mutualisms: Can red imported fire ants sour the relationship? Biol. Conserv. 2001, 101, 249-253
    • (2001) Biol. Conserv , vol.101 , pp. 249-253
    • Zettler, J.A.1    Spira, T.P.2    Allen, C.R.3
  • 42
    • 0000758804 scopus 로고
    • Seed predation by rodents on three ant-dispersed plants
    • Heithaus, E.R. Seed predation by rodents on three ant-dispersed plants. Ecology 1981, 136-145
    • (1981) Ecology , pp. 136-145
    • Heithaus, E.R.1
  • 45
    • 0030799767 scopus 로고    scopus 로고
    • Influence of sunlight and soil nutrients on clonal growth and sexual reproduction of the understory perennial herb Sanguinaria canadensis L
    • Marino, P.C.; Eisenberg, R.M.; Cornell, H.V. Influence of sunlight and soil nutrients on clonal growth and sexual reproduction of the understory perennial herb Sanguinaria canadensis L. J. Torrey Bot. Soc. 1997, 219-227
    • (1997) J. Torrey Bot. Soc , pp. 219-227
    • Marino, P.C.1    Eisenberg, R.M.2    Cornell, H.V.3
  • 46
    • 84887291778 scopus 로고    scopus 로고
    • Hybrid poplar plantations are suitable habitat for reintroduced forest herbs with conservation status
    • Boothroyd-Roberts, K.; Gagnon, D.; Truax, B. Hybrid poplar plantations are suitable habitat for reintroduced forest herbs with conservation status. SpringerPlus 2013, 2, 507
    • (2013) Springerplus , vol.2
    • Boothroyd-Roberts, K.1    Gagnon, D.2    Truax, B.3
  • 47
    • 0034868934 scopus 로고    scopus 로고
    • Elevational trends in defense chemistry, vegetation, and reproduction in Sanguinaria canadensis
    • Salmore, A.K.; Hunter, M.D. Elevational trends in defense chemistry, vegetation, and reproduction in Sanguinaria canadensis. J. Chem. Ecol. 2001, 27, 1713-1727
    • (2001) J. Chem. Ecol. , vol.27 , pp. 1713-1727
    • Salmore, A.K.1    Hunter, M.D.2
  • 49
    • 34250306137 scopus 로고
    • Algonkian words in american english: A study in the contact of the white man and the Indian
    • Chamberlain, A.F. Algonkian words in american english: A study in the contact of the white man and the Indian. J. Am. Folk. 1902, 15, 240-267
    • (1902) J. Am. Folk , vol.15 , pp. 240-267
    • Chamberlain, A.F.1
  • 52
    • 0003439481 scopus 로고
    • Syracuse University Press: Syracuse, NY, USA
    • Herrick, J.W.; Snow, D.R. Iroquois Medical Botany; Syracuse University Press: Syracuse, NY, USA, 1995; pp. 127-128.
    • (1995) Iroquois Medical Botany , pp. 127-128
    • Herrick, J.W.1    Snow, D.R.2
  • 53
    • 0008906903 scopus 로고
    • Order of the Board of Trustees: Milwaukee, WI, USA
    • Smith, H.H. Ethnobotany of the Ojibwe Indians; Order of the Board of Trustees: Milwaukee, WI, USA, 1932; pp. 377-378.
    • (1932) Ethnobotany of the Ojibwe Indians , pp. 377-378
    • Smith, H.H.1
  • 57
    • 1542656697 scopus 로고
    • Uses of plants by the Chippewa Indians
    • Densmore, F. Uses of plants by the Chippewa Indians. Bur. Am. Ethnol. Bull. 1928, 44, 275-397.
    • (1928) Bur. Am. Ethnol. Bull , vol.44 , pp. 275-397
    • Densmore, F.1
  • 58
    • 21544449850 scopus 로고
    • The malecite Indians, with notes on the Micmacs (Concluded)
    • Mechling, W.H. The malecite Indians, with notes on the Micmacs (concluded). Anthropologica 1959, 8, 161-274
    • (1959) Anthropologica , vol.8 , pp. 161-274
    • Mechling, W.H.1
  • 59
    • 5644234705 scopus 로고
    • Ethnobotanique abénaklse
    • Rousseau, J. Ethnobotanique abénaklse. Arch. Folk. 1947, 11, 145-182.
    • (1947) Arch. Folk , vol.11 , pp. 145-182
    • Rousseau, J.1
  • 61
    • 0000456205 scopus 로고
    • Public Museum of the City of Milwaukee: Milwaukee, WI, USA
    • Smith, H.H. Ethnobotany of the Meskwaki Indians; Public Museum of the City of Milwaukee: Milwaukee, WI, USA, 1928.
    • (1928) Ethnobotany of the Meskwaki Indians
    • Smith, H.H.1
  • 62
    • 0021028405 scopus 로고
    • Vindication of maritime Indian herbal remedies
    • Chandler, R.F. Vindication of maritime Indian herbal remedies. J. Ethnopharmacol. 1983, 9, 323-327
    • (1983) J. Ethnopharmacol , vol.9 , pp. 323-327
    • Chandler, R.F.1
  • 64
    • 28844488422 scopus 로고
    • Medicinal plants and Appalachia
    • Krochmal, A. Medicinal plants and Appalachia. Econ. Bot. 1968, 22, 332-337
    • (1968) Econ. Bot , vol.22 , pp. 332-337
    • Krochmal, A.1
  • 66
    • 84965208869 scopus 로고
    • The Sanguinaria canadensis: Its natural history, properties, and medical uses
    • Gibb, G.D. The Sanguinaria canadensis: Its natural history, properties, and medical uses. BMJ 1860, 4, 104-107
    • (1860) BMJ , vol.4 , pp. 104-107
    • Gibb, G.D.1
  • 67
    • 84984811621 scopus 로고
    • Remarks on the treatment of tracheitis, or croup
    • Allen, J.A. Remarks on the treatment of tracheitis, or croup. Boston Med. Surg. J. 1845, 33, 389-392
    • (1845) Boston Med. Surg. J , vol.33 , pp. 389-392
    • Allen, J.A.1
  • 69
    • 84984844743 scopus 로고
    • On the use of Sanguinaria
    • Leonard, J. On the use of Sanguinaria. Boston Med. Surg. J. 1845, 32, 457-459
    • (1845) Boston Med. Surg. J. , vol.32 , pp. 457-459
    • Leonard, J.1
  • 70
    • 0030267470 scopus 로고    scopus 로고
    • A history of rhinology in North America
    • Leopold, D. A history of rhinology in North America. Otolaryngol. Head Neck Surg. 1996, 115, 283-297
    • (1996) Otolaryngol. Head Neck Surg , vol.115 , pp. 283-297
    • Leopold, D.1
  • 72
    • 84897226249 scopus 로고
    • 2nd ed.; Thomas B. Wait & Co. and C. Williams: Boston, MA, USA
    • Thatcher, J. The American New Dispensatory, 2nd ed.; Thomas B. Wait & Co. and C. Williams: Boston, MA, USA, 1813; pp. 201-204.
    • (1813) The American New Dispensatory , pp. 201-204
    • Thatcher, J.1
  • 74
    • 84984829152 scopus 로고
    • Sanguinarine and its salts: On the medicinal powers of sanguinarine and its salts
    • William, T. Sanguinarine and its salts: On the medicinal powers of sanguinarine and its salts. Boston Med. Surg. J. 1832, 6, 245-248
    • (1832) Boston Med. Surg. J , vol.6 , pp. 245-248
    • William, T.1
  • 76
    • 84984797162 scopus 로고
    • On Sanguinaria canadensis
    • Smith, D.B. On Sanguinaria canadensis. Boston Med. Surg. J. 1832, 5, 393-395
    • (1832) Boston Med. Surg. J. , vol.5 , pp. 393-395
    • Smith, D.B.1
  • 78
    • 85052252525 scopus 로고
    • Blanchard and Lea: Philadelphia, PA, USA
    • Stillé, A. Therapeutics and Materia Medica; Blanchard and Lea: Philadelphia, PA, USA, 1874; Volume 2, pp. 454-457.
    • (1874) Therapeutics and Materia Medica , vol.2 , pp. 454-457
    • Stillé, A.1
  • 79
    • 0005598007 scopus 로고
    • Wm. H. Cook: Cincinnati, OH, USA
    • Cook, W. The Physiomedical Dispensatory; Wm. H. Cook: Cincinnati, OH, USA, 1869; pp. 466-467.
    • (1869) The Physiomedical Dispensatory , pp. 466-467
    • Cook, W.1
  • 80
    • 84984817433 scopus 로고
    • Betts & Anstice: New York, NY, USA
    • Beach, W. The American Practice of Medicine; Betts & Anstice: New York, NY, USA, 1833; Volume 2, pp. 259-261.
    • (1833) The American Practice of Medicine , vol.2 , pp. 259-261
    • Beach, W.1
  • 83
    • 0021249304 scopus 로고
    • Herbal remedies of the maritime Indians: Phytosterols and triterpenes of 67 plants
    • Hooper, S.N.; Chandler, R.F. Herbal remedies of the maritime Indians: Phytosterols and triterpenes of 67 plants. J. Ethnopharmacol. 1984, 10, 181-194
    • (1984) J. Ethnopharmacol , vol.10 , pp. 181-194
    • Hooper, S.N.1    Chandler, R.F.2
  • 84
    • 0042723644 scopus 로고
    • An account of some experiments on the root of the Sanguinaria canadensis
    • Dana, J.F. An account of some experiments on the root of the Sanguinaria canadensis. N. Y. Med. Phys. J. 1827, 6, 218-222
    • (1827) N. Y. Med. Phys. J , vol.6 , pp. 218-222
    • Dana, J.F.1
  • 85
    • 2042428577 scopus 로고
    • Beschreibung und Dartsellungsweise einiger bei der Analyse de Chelidonium majus neu aufgefundenen Stoffe
    • Probst, Q.M. Beschreibung und Dartsellungsweise einiger bei der Analyse de Chelidonium majus neu aufgefundenen Stoffe. Justus Liebigs Ann. Chem. 1839, 29, 113
    • (1839) Justus Liebigs Ann. Chem , vol.29
    • Probst, Q.M.1
  • 86
    • 84980086949 scopus 로고
    • Über Papaveraceen-Alkaloïde
    • Konig, G. Über Papaveraceen-Alkaloïde. Arch. Pharm. 1893, 231, 177
    • (1893) Arch. Pharm , vol.231
    • Konig, G.1
  • 87
    • 0043224888 scopus 로고
    • Chelerythrine and sanguinarine
    • Gadamer, J.; Stichel, A. Chelerythrine and sanguinarine. Arch. Pharm. 1924, 262, 488-500.
    • (1924) Arch. Pharm , vol.262 , pp. 488-500
    • Gadamer, J.1    Stichel, A.2
  • 88
    • 4243286604 scopus 로고
    • Alkaloide der mohngewachse (Papaveraceae) X. Uber die nebenalkaloide des klatschmohns (Papaver rhoeas L.) und der herzblume (Dicentra spectabilis L.)
    • Slavik, J. Alkaloide der mohngewachse (Papaveraceae) X. Uber die nebenalkaloide des klatschmohns (Papaver rhoeas L.) und der herzblume (Dicentra spectabilis L.). Collect. Czech. Chem. Commun. 1959, 24, 2506-2515
    • (1959) Collect. Czech. Chem. Commun , vol.24 , pp. 2506-2515
    • Slavik, J.1
  • 89
    • 34047248049 scopus 로고    scopus 로고
    • HPLC quantification of seven quaternary benzo[c]phenanthridine alkaloids in six species of the family papaveraceae
    • Suchomelova, J.; Bochorakova, H.; Paulova, H.; Musil, P.; Taborska, E. HPLC quantification of seven quaternary benzo[c]phenanthridine alkaloids in six species of the family papaveraceae. J. Pharm. Biomed. Anal. 2007, 44, 283-287
    • (2007) J. Pharm. Biomed. Anal , vol.44 , pp. 283-287
    • Suchomelova, J.1    Bochorakova, H.2    Paulova, H.3    Musil, P.4    Taborska, E.5
  • 90
    • 35148850526 scopus 로고    scopus 로고
    • Spatial and temporal distribution of the alkaloid sanguinarine in Sanguinaria canadensis L. (bloodroot)
    • Campbell, S.; Affolter, J.; Randle, W. Spatial and temporal distribution of the alkaloid sanguinarine in Sanguinaria canadensis L. (bloodroot). Econ. Bot. 2007, 61, 223-234
    • (2007) Econ. Bot , vol.61 , pp. 223-234
    • Campbell, S.1    Affolter, J.2    Randle, W.3
  • 91
    • 84984827779 scopus 로고
    • What is the proper time for the collection of sanguinaria
    • Homerberg, V.; Beringer, G. What is the proper time for the collection of sanguinaria? J. Am. Pharm. Assoc. 1913, 2, 1302
    • (1913) J. Am. Pharm. Assoc , vol.2
    • Homerberg, V.1    Beringer, G.2
  • 92
    • 84984827778 scopus 로고
    • The proper time to collect sanguinaria
    • Farwell, O.A. The proper time to collect sanguinaria. Am. J. Pham. 1915, 87, 97-98.
    • (1915) Am. J. Pham , vol.87 , pp. 97-98
    • Farwell, O.A.1
  • 94
    • 0026567845 scopus 로고
    • Growth characteristics of Sanguinaria canadensis L. Cell suspensions and immobilized cultures for production of benzophenanthridine alkaloids
    • Rho, D.; Chauret, N.; Laberge, N.; Archambault, J. Growth characteristics of Sanguinaria canadensis L. Cell suspensions and immobilized cultures for production of benzophenanthridine alkaloids. Appl. Microbiol. Biotechnol. 1992, 36, 611-617
    • (1992) Appl. Microbiol. Biotechnol. , vol.36 , pp. 611-617
    • Rho, D.1    Chauret, N.2    Laberge, N.3    Archambault, J.4
  • 95
    • 0023118417 scopus 로고
    • Short-term toxicity studies of sanguinarine and of two alkaloid extracts of Sanguinaria canadensis L
    • Becci, P.J.; Schwartz, H.; Barnes, H.H.; Southard, G.L. Short-term toxicity studies of sanguinarine and of two alkaloid extracts of Sanguinaria canadensis L. J. Toxicol. Environ. Health 1987, 20, 199-208
    • (1987) J. Toxicol. Environ. Health , vol.20 , pp. 199-208
    • Becci, P.J.1    Schwartz, H.2    Barnes, H.H.3    Southard, G.L.4
  • 96
    • 0000109450 scopus 로고
    • Alkaloid-bearing plants: An ecogeographic perspective
    • Levin, D.A. Alkaloid-bearing plants: An ecogeographic perspective. Am. Nat. 1976, 110, 261-284
    • (1976) Am. Nat , vol.110 , pp. 261-284
    • Levin, D.A.1
  • 97
    • 0001752965 scopus 로고
    • A latitudinal gradient in rates of ant predation
    • Jeanne, R.L. A latitudinal gradient in rates of ant predation. Ecology 1979, 60, 1211-1224
    • (1979) Ecology , vol.60 , pp. 1211-1224
    • Jeanne, R.L.1
  • 98
    • 0001903781 scopus 로고
    • The toxicity of plant alkaloids: An ecogeographic perspective
    • Levin, D.A. The toxicity of plant alkaloids: An ecogeographic perspective. Biochem. Syst. Ecol. 1978, 6, 61-76
    • (1978) Biochem. Syst. Ecol , vol.6 , pp. 61-76
    • Levin, D.A.1
  • 99
    • 0000966606 scopus 로고
    • Berberine contents and alkaloid profile of berberis species from different altitudes
    • Chandra, P.; Purohit, A. Berberine contents and alkaloid profile of berberis species from different altitudes. Biochem. Syst. Ecol. 1980, 8, 379-380
    • (1980) Biochem. Syst. Ecol , vol.8 , pp. 379-380
    • Chandra, P.1    Purohit, A.2
  • 100
    • 0028110570 scopus 로고
    • Elevational variation of quinolizidine alkaloid contents in a lupine (Lupinus argenteus) of the Rocky Mountains
    • Carey, D.B.; Wink, M. Elevational variation of quinolizidine alkaloid contents in a lupine (Lupinus argenteus) of the Rocky Mountains. J. Chem. Ecol. 1994, 20, 849-857
    • (1994) J. Chem. Ecol , vol.20 , pp. 849-857
    • Carey, D.B.1    Wink, M.2
  • 101
    • 79955533556 scopus 로고    scopus 로고
    • Seasonal variation of bioactive alkaloid contents in Macleaya microcarpa (Maxim.) Fedde
    • Pencikova, K.; Urbanova, J.; Musil, P.; Taborska, E.; Gregorova, J. Seasonal variation of bioactive alkaloid contents in Macleaya microcarpa (Maxim.) Fedde. Molecules 2011, 16, 3391-3401
    • (2011) Molecules , vol.16 , pp. 3391-3401
    • Pencikova, K.1    Urbanova, J.2    Musil, P.3    Taborska, E.4    Gregorova, J.5
  • 103
    • 84989691463 scopus 로고
    • The effect of PH on the absorption and fluorescence-spectra of sanguinarine
    • Maiti, M.; Nandi, R.; Chaudhuri, K. The effect of PH on the absorption and fluorescence-spectra of sanguinarine. Photochem. Photobiol. 1983, 38, 245-249
    • (1983) Photochem. Photobiol , vol.38 , pp. 245-249
    • Maiti, M.1    Nandi, R.2    Chaudhuri, K.3
  • 104
    • 0022884335 scopus 로고
    • The effect of PH on sanguinarine iminium ion form
    • Jones, R.R.; Harkrader, R.J.; Southard, G.L. The effect of PH on sanguinarine iminium ion form. J. Nat. Prod. 1986, 49, 1109-1111
    • (1986) J. Nat. Prod , vol.49 , pp. 1109-1111
    • Jones, R.R.1    Harkrader, R.J.2    Southard, G.L.3
  • 105
    • 0025381503 scopus 로고
    • Sequence-selective, pH-dependent binding to DNA of benzophenanthridine alkaloids
    • Bajaj, N.P.; McLean, M.J.; Waring, M.J.; Smekal, E. Sequence-selective, pH-dependent binding to DNA of benzophenanthridine alkaloids. J. Mol. Recognit. 1990, 3, 48-54
    • (1990) J. Mol. Recognit , vol.3 , pp. 48-54
    • Bajaj, N.P.1    McLean, M.J.2    Waring, M.J.3    Smekal, E.4
  • 106
    • 6944253337 scopus 로고    scopus 로고
    • The effect of the antineoplastic drug ukrain on the electrokinetic potential of malignant and normal cells
    • Todor, I. The effect of the antineoplastic drug ukrain on the electrokinetic potential of malignant and normal cells. Int. J. Immunother. 2003, 19, 159-168.
    • (2003) Int. J. Immunother , vol.19 , pp. 159-168
    • Todor, I.1
  • 107
    • 0036917594 scopus 로고    scopus 로고
    • Influence of DNA structures on the conversion of sanguinarine alkanolamine form to iminium form
    • Maiti, M.; Das, S.; Sen, A.; Das, A.; Kumar, G.S.; Nandi, R. Influence of DNA structures on the conversion of sanguinarine alkanolamine form to iminium form. J. Biomol. Struct. Dyn. 2002, 20, 455-464
    • (2002) J. Biomol. Struct. Dyn , vol.20 , pp. 455-464
    • Maiti, M.1    Das, S.2    Sen, A.3    Das, A.4    Kumar, G.S.5    Nandi, R.6
  • 108
    • 34548312218 scopus 로고    scopus 로고
    • Quaternary benzo[c]phenanthridine alkaloids-Novel cell permeant and red fluorescing DNA probes
    • Slaninova, I.; Slanina, J.; Taborska, E. Quaternary benzo[c]phenanthridine alkaloids-Novel cell permeant and red fluorescing DNA probes. Cytom. A 2007, 71, 700-708
    • (2007) Cytom. A , vol.71 , pp. 700-708
    • Slaninova, I.1    Slanina, J.2    Taborska, E.3
  • 109
    • 33745631235 scopus 로고    scopus 로고
    • DNA-binding affinities and sequence selectivity of quaternary benzophenanthridine alkaloids sanguinarine, chelerythrine, and nitidine
    • Bai, L.P.; Zhao, Z.Z.; Cai, Z.; Jiang, Z.H. DNA-binding affinities and sequence selectivity of quaternary benzophenanthridine alkaloids sanguinarine, chelerythrine, and nitidine. Bioorg. Med. Chem. 2006, 14, 5439-5445
    • (2006) Bioorg. Med. Chem , vol.14 , pp. 5439-5445
    • Bai, L.P.1    Zhao, Z.Z.2    Cai, Z.3    Jiang, Z.H.4
  • 110
    • 0017886244 scopus 로고
    • Analysis of binding of daunorubicin and doxorubicin to DNA using computerized curve-fitting procedures
    • Byrn, S.R.; Dolch, G.D. Analysis of binding of daunorubicin and doxorubicin to DNA using computerized curve-fitting procedures. J. Pharm. Sci. 1978, 67, 688-693
    • (1978) J. Pharm. Sci. , vol.67 , pp. 688-693
    • Byrn, S.R.1    Dolch, G.D.2
  • 111
    • 0034946675 scopus 로고    scopus 로고
    • Solution chemistry and DNA binding properties of men 10755, a novel disaccharide analogue of doxorubicin
    • Messori, L.; Temperini, C.; Piccioli, F.; Animati, F.; Di Bugno, C.; Orioli, P. Solution chemistry and DNA binding properties of men 10755, a novel disaccharide analogue of doxorubicin. Bioorg. Med. Chem. 2001, 9, 1815-1825
    • (2001) Bioorg. Med. Chem , vol.9 , pp. 1815-1825
    • Messori, L.1    Temperini, C.2    Piccioli, F.3    Animati, F.4    Di Bugno, C.5    Orioli, P.6
  • 112
    • 4444220152 scopus 로고    scopus 로고
    • Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery
    • Adhami, V.M.; Aziz, M.H.; Reagan-Shaw, S.R.; Nihal, M.; Mukhtar, H.; Ahmad, N. Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery. Mol. Cancer Ther. 2004, 3, 933-940
    • (2004) Mol. Cancer Ther , vol.3 , pp. 933-940
    • Adhami, V.M.1    Aziz, M.H.2    Reagan-Shaw, S.R.3    Nihal, M.4    Mukhtar, H.5    Ahmad, N.6
  • 113
    • 64649090292 scopus 로고    scopus 로고
    • Targeting DNA topoisomerase ii in cancer chemotherapy
    • Nitiss, J.L. Targeting DNA topoisomerase ii in cancer chemotherapy. Nat. Rev. Cancer 2009, 9, 338-350
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 338-350
    • Nitiss, J.L.1
  • 114
    • 33645840140 scopus 로고    scopus 로고
    • Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine
    • Holy, J.; Lamont, G.; Perkins, E. Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine. BMC Cell Biol. 2006, 7, 13
    • (2006) BMC Cell Biol , vol.7
    • Holy, J.1    Lamont, G.2    Perkins, E.3
  • 115
    • 81855198087 scopus 로고    scopus 로고
    • All tangled up: How cells direct, manage and exploit topoisomerase function
    • Vos, S.M.; Tretter, E.M.; Schmidt, B.H.; Berger, J.M. All tangled up: How cells direct, manage and exploit topoisomerase function. Nat. Rev. Mol. Cell Biol. 2011, 12, 827-841
    • (2011) Nat. Rev. Mol. Cell Biol , vol.12 , pp. 827-841
    • Vos, S.M.1    Tretter, E.M.2    Schmidt, B.H.3    Berger, J.M.4
  • 116
    • 77953381213 scopus 로고    scopus 로고
    • Structural insights into G-quadruplexes: Towards new anticancer drugs
    • Yang, D.; Okamoto, K. Structural insights into G-quadruplexes: Towards new anticancer drugs. Future Med. Chem. 2010, 2, 619-646
    • (2010) Future Med. Chem , vol.2 , pp. 619-646
    • Yang, D.1    Okamoto, K.2
  • 117
    • 59449107619 scopus 로고    scopus 로고
    • Ligand binding to tandem g quadruplexes from human telomeric DNA
    • Bai, L.P.; Hagihara, M.; Jiang, Z.H.; Nakatani, K. Ligand binding to tandem g quadruplexes from human telomeric DNA. ChemBioChem 2008, 9, 2583-2587
    • (2008) Chembiochem , vol.9 , pp. 2583-2587
    • Bai, L.P.1    Hagihara, M.2    Jiang, Z.H.3    Nakatani, K.4
  • 118
    • 84894040720 scopus 로고    scopus 로고
    • Competitive binding assay for G-quadruplex DNA and sanguinarine based on room temperature phosphorescence of Mn-doped ZnS quantum dots
    • Wen, L.N.; Xie, M.X. Competitive binding assay for G-quadruplex DNA and sanguinarine based on room temperature phosphorescence of Mn-doped ZnS quantum dots. J. Photochem. Photobiol. A Chem. 2014, 279, 24-31
    • (2014) J. Photochem. Photobiol. A Chem. , vol.279 , pp. 24-31
    • Wen, L.N.1    Xie, M.X.2
  • 119
    • 79960840968 scopus 로고    scopus 로고
    • Binding properties of human telomeric quadruplex multimers: A new route for drug design
    • Cummaro, A.; Fotticchia, I.; Franceschin, M.; Giancola, C.; Petraccone, L. Binding properties of human telomeric quadruplex multimers: A new route for drug design. Biochimie 2011, 93, 1392-1400
    • (2011) Biochimie , vol.93 , pp. 1392-1400
    • Cummaro, A.1    Fotticchia, I.2    Franceschin, M.3    Giancola, C.4    Petraccone, L.5
  • 120
    • 84859484109 scopus 로고    scopus 로고
    • The interaction of telomeric DNA and c-myc22 G-quadruplex with 11 natural alkaloids
    • Ji, X.; Sun, H.; Zhou, H.; Xiang, J.; Tang, Y.; Zhao, C. The interaction of telomeric DNA and c-myc22 G-quadruplex with 11 natural alkaloids. Nucleic Acid Ther. 2012, 22, 127-136
    • (2012) Nucleic Acid Ther , vol.22 , pp. 127-136
    • Ji, X.1    Sun, H.2    Zhou, H.3    Xiang, J.4    Tang, Y.5    Zhao, C.6
  • 121
    • 33646241080 scopus 로고    scopus 로고
    • The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding. A possible mechanism for its antiproliferative activity
    • Lopus, M.; Panda, D. The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding. A possible mechanism for its antiproliferative activity. FEBS J. 2006, 273, 2139-2150
    • (2006) FEBS J , vol.273 , pp. 2139-2150
    • Lopus, M.1    Panda, D.2
  • 122
    • 0027742463 scopus 로고
    • Antimicrotubule properties of benzophenanthridine alkaloids
    • Wolff, J.; Knipling, L. Antimicrotubule properties of benzophenanthridine alkaloids. Biochemistry 1993, 32, 13334-13339
    • (1993) Biochemistry , vol.32 , pp. 13334-13339
    • Wolff, J.1    Knipling, L.2
  • 123
    • 0024425127 scopus 로고
    • A cis-acting transcription element of the c-myc gene can assume an H-DNA conformation
    • Kinniburgh, A.J. A cis-acting transcription element of the c-myc gene can assume an H-DNA conformation. Nucleic Acids Res. 1989, 17, 7771-7778
    • (1989) Nucleic Acids Res , vol.17 , pp. 7771-7778
    • Kinniburgh, A.J.1
  • 126
    • 0029198606 scopus 로고
    • The binding of analogues of coralyne and related heterocyclics to DNA triplexes. Biochem
    • Latimer, L.J.; Payton, N.; Forsyth, G.; Lee, J.S. The binding of analogues of coralyne and related heterocyclics to DNA triplexes. Biochem. Cell Biol. 1995, 73, 11-18
    • (1995) Cell Biol , vol.73 , pp. 11-18
    • Latimer, L.J.1    Payton, N.2    Forsyth, G.3    Lee, J.S.4
  • 127
    • 0037386852 scopus 로고    scopus 로고
    • Spectroscopic and thermodynamic studies on the binding of sanguinarine and berberine to triple and double helical DNA and RNA structures
    • Das, S.; Kumar, G.S.; Ray, A.; Maiti, M. Spectroscopic and thermodynamic studies on the binding of sanguinarine and berberine to triple and double helical DNA and RNA structures. J. Biomol. Struct. Dyn. 2003, 20, 703-713
    • (2003) J. Biomol. Struct. Dyn , vol.20 , pp. 703-713
    • Das, S.1    Kumar, G.S.2    Ray, A.3    Maiti, M.4
  • 128
    • 0033035891 scopus 로고    scopus 로고
    • Conversions of the left-handed form and the protonated form of DNA back to the bound right-handed form by sanguinarine and ethidium: A comparative study
    • Das, S.; Kumar, G.S.; Maiti, M. Conversions of the left-handed form and the protonated form of DNA back to the bound right-handed form by sanguinarine and ethidium: A comparative study. Biophys. Chem. 1999, 76, 199-218
    • (1999) Biophys. Chem. , vol.76 , pp. 199-218
    • Das, S.1    Kumar, G.S.2    Maiti, M.3
  • 129
    • 0027937691 scopus 로고
    • Speculation on the biological roles of left-handed Z-DNAa
    • Rich, A. Speculation on the biological roles of left-handed Z-DNAa. Ann. N. Y. Acad. Sci. 1994, 726, 1-17
    • (1994) Ann. N. Y. Acad. Sci , vol.726 , pp. 1-17
    • Rich, A.1
  • 131
    • 0026323444 scopus 로고
    • Inhibition of the B to Z transition in poly (DGdC). Cntdot. Poly (dGdC) by covalent attachment of ethidium: Kinetic studies
    • Gilbert, P.L.; Graves, D.E.; Britt, M.; Chaires, J.B. Inhibition of the B to Z transition in poly (dGdC). Cntdot. Poly (dGdC) by covalent attachment of ethidium: Kinetic studies. Biochemistry 1991, 30, 10931-10937
    • (1991) Biochemistry , vol.30 , pp. 10931-10937
    • Gilbert, P.L.1    Graves, D.E.2    Britt, M.3    Chaires, J.B.4
  • 132
    • 65649086094 scopus 로고    scopus 로고
    • Molecular aspects of small molecules-poly(A) interaction: An approach to RNA based drug design
    • Giri, P.; Kumar, G.S. Molecular aspects of small molecules-poly(A) interaction: An approach to RNA based drug design. Curr. Med. Chem. 2009, 16, 965-987
    • (2009) Curr. Med. Chem , vol.16 , pp. 965-987
    • Giri, P.1    Kumar, G.S.2
  • 133
    • 77953594301 scopus 로고    scopus 로고
    • Binding of the anticancer alkaloid sanguinarine to double stranded rnas: Insights into the structural and energetics aspects
    • Chowdhury, S.R.; Islam, M.M.; Kumar, G.S. Binding of the anticancer alkaloid sanguinarine to double stranded rnas: Insights into the structural and energetics aspects. Mol. Biosyst. 2010, 6, 1265-1276
    • (2010) Mol. Biosyst. , vol.6 , pp. 1265-1276
    • Chowdhury, S.R.1    Islam, M.M.2    Kumar, G.S.3
  • 134
    • 84929589862 scopus 로고    scopus 로고
    • Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach
    • Singh, C.K.; Kaur, S.; George, J.; Nihal, M.; Hahn, M.C.P.; Scarlett, C.O.; Ahmad, N. Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach. Oncotarget 2015, 6, 10335-10348
    • (2015) Oncotarget , vol.6 , pp. 10335-10348
    • Singh, C.K.1    Kaur, S.2    George, J.3    Nihal, M.4    Hahn, M.C.P.5    Scarlett, C.O.6    Ahmad, N.7
  • 135
    • 48849113980 scopus 로고    scopus 로고
    • Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis
    • Matkar, S.S.; Wrischnik, L.A.; Hellmann-Blumberg, U. Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis. Arch. Biochem. Biophys. 2008, 477, 43-52
    • (2008) Arch. Biochem. Biophys , vol.477 , pp. 43-52
    • Matkar, S.S.1    Wrischnik, L.A.2    Hellmann-Blumberg, U.3
  • 137
    • 0347285302 scopus 로고    scopus 로고
    • Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism
    • Vrba, J.; Hrbac, J.; Ulrichova, J.; Modriansky, M. Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism. Chem. Biol. Interact. 2004, 147, 35-47
    • (2004) Chem. Biol. Interact , vol.147 , pp. 35-47
    • Vrba, J.1    Hrbac, J.2    Ulrichova, J.3    Modriansky, M.4
  • 139
    • 84931390369 scopus 로고    scopus 로고
    • Sanguinarine-induced apoptosis in lung adenocarcinoma cells is dependent on reactive oxygen species production and endoplasmic reticulum stress
    • Gu, S.; Yang, X.-C.; Xiang, X.-Y.; Wu, Y.A.O.; Zhang, Y.U.; Yan, X.-Y.; Xue, Y.-N.; Sun, L.-K.; Shao, G.-G. Sanguinarine-induced apoptosis in lung adenocarcinoma cells is dependent on reactive oxygen species production and endoplasmic reticulum stress. Oncol. Rep. 2015, 34, 913-919
    • (2015) Oncol. Rep , vol.34 , pp. 913-919
    • Gu, S.1    Yang, X.-C.2    Xiang, X.-Y.3    Wu, Y.A.O.4    Zhang, Y.U.5    Yan, X.-Y.6    Xue, Y.-N.7    Sun, L.-K.8    Shao, G.-G.9
  • 140
    • 36248949141 scopus 로고    scopus 로고
    • The Endoplasmic Reticulum and the Unfolded Protein Response
    • Malhotra, J.D.; Kaufman, R.J. The Endoplasmic Reticulum and the Unfolded Protein Response. Semin. Cell Dev. Biol. 2007, 18, 716-731
    • (2007) Semin. Cell Dev. Biol , vol.18 , pp. 716-731
    • Malhotra, J.D.1    Kaufman, R.J.2
  • 141
    • 84857217832 scopus 로고    scopus 로고
    • Er stress and its functional link to mitochondria: Role in cell survival and death
    • Malhotra, J.D.; Kaufman, R.J. Er stress and its functional link to mitochondria: Role in cell survival and death. Cold Spring Harb. Perspect. Biol. 2011, 3, a004424
    • (2011) Cold Spring Harb. Perspect. Biol , vol.3
    • Malhotra, J.D.1    Kaufman, R.J.2
  • 142
    • 35848957485 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword?
    • Malhotra, J.D.; Kaufman, R.J. Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword? Antioxid. Redox Signal. 2007, 9, 2277-2294
    • (2007) Antioxid. Redox Signal , vol.9 , pp. 2277-2294
    • Malhotra, J.D.1    Kaufman, R.J.2
  • 145
    • 0033088957 scopus 로고    scopus 로고
    • The role of glutathione in the regulation of apoptosis
    • Hall, A. The role of glutathione in the regulation of apoptosis. Eur. J. Clin. Investig. 1999, 29, 238-245
    • (1999) Eur. J. Clin. Investig , vol.29 , pp. 238-245
    • Hall, A.1
  • 146
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • Kerbel, R.S. Tumor angiogenesis. N. Engl. J. Med. 2008, 358, 2039-2049
    • (2008) N. Engl. J. Med , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 147
    • 0036780251 scopus 로고    scopus 로고
    • Clinical translation of angiogenesis inhibitors
    • Kerbel, R.; Folkman, J. Clinical translation of angiogenesis inhibitors. Nat. Rev. Cancer 2002, 2, 727-739
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 727-739
    • Kerbel, R.1    Folkman, J.2
  • 148
    • 1842583588 scopus 로고    scopus 로고
    • Suppression of angiogenesis by the plant alkaloid, sanguinarine
    • Eun, J.P.; Koh, G.Y. Suppression of angiogenesis by the plant alkaloid, sanguinarine. Biochem. Biophys. Res. Commun. 2004, 317, 618-624
    • (2004) Biochem. Biophys. Res. Commun , vol.317 , pp. 618-624
    • Eun, J.P.1    Koh, G.Y.2
  • 150
    • 33749326967 scopus 로고    scopus 로고
    • The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine
    • Malikova, J.; Zdarilova, A.; Hlobilkova, A.; Ulrichova, J. The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine. Cell Biol. Toxicol. 2006, 22, 439-453
    • (2006) Cell Biol. Toxicol , vol.22 , pp. 439-453
    • Malikova, J.1    Zdarilova, A.2    Hlobilkova, A.3    Ulrichova, J.4
  • 151
    • 0033961302 scopus 로고    scopus 로고
    • In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo
    • Chmura, S.J.; Dolan, M.E.; Cha, A.; Mauceri, H.J.; Kufe, D.W.; Weichselbaum, R.R. In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo. Clin. Cancer Res. 2000, 6, 737-742
    • (2000) Clin. Cancer Res , vol.6 , pp. 737-742
    • Chmura, S.J.1    Dolan, M.E.2    Cha, A.3    Mauceri, H.J.4    Kufe, D.W.5    Weichselbaum, R.R.6
  • 152
    • 0034737435 scopus 로고    scopus 로고
    • Activation of p38 and c-Jun N-terminal kinase pathways and induction of apoptosis by chelerythrine do not require inhibition of protein kinase C
    • Yu, R.; Mandlekar, S.; Tan, T.-H.; Kong, A.-N.T. Activation of p38 and c-Jun N-terminal kinase pathways and induction of apoptosis by chelerythrine do not require inhibition of protein kinase C. J. Biol. Chem. 2000, 275, 9612-9619
    • (2000) J. Biol. Chem , vol.275 , pp. 9612-9619
    • Yu, R.1    Mandlekar, S.2    Tan, T.-H.3    Kong, A.-N.T.4
  • 154
    • 84921824443 scopus 로고    scopus 로고
    • Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: A paradigm shift
    • Medvetz, D.; Priolo, C.; Henske, E.P. Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: A paradigm shift. Mol. Cancer Res. 2015, 13, 3-8
    • (2015) Mol. Cancer Res. , vol.13 , pp. 3-8
    • Medvetz, D.1    Priolo, C.2    Henske, E.P.3
  • 155
    • 33947259466 scopus 로고    scopus 로고
    • Screening of minor benzo[c]phenanthridine alkaloids for antiproliferative and apoptotic activities
    • Slaninova, I.; Slunska, Z.; Sinkora, J.; Vlkova, M.; Taborska, E. Screening of minor benzo[c]phenanthridine alkaloids for antiproliferative and apoptotic activities. Pharm. Biol. 2007, 45, 131-139
    • (2007) Pharm. Biol. , vol.45 , pp. 131-139
    • Slaninova, I.1    Slunska, Z.2    Sinkora, J.3    Vlkova, M.4    Taborska, E.5
  • 156
    • 79952705778 scopus 로고    scopus 로고
    • Benzo[c]phenanthridine alkaloids exhibit strong anti-proliferative activity in malignant melanoma cells regardless of their p53 status
    • Hammerova, J.; Uldrijan, S.; Taborska, E.; Slaninova, I. Benzo[c]phenanthridine alkaloids exhibit strong anti-proliferative activity in malignant melanoma cells regardless of their p53 status. J. Dermatol. Sci. 2011, 62, 22-35
    • (2011) J. Dermatol. Sci , vol.62 , pp. 22-35
    • Hammerova, J.1    Uldrijan, S.2    Taborska, E.3    Slaninova, I.4
  • 157
    • 77649182612 scopus 로고    scopus 로고
    • Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells
    • Slunska, Z.; Gelnarova, E.; Hammerova, J.; Taborska, E.; Slaninova, I. Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells. Toxicol. in Vitro 2010, 24, 697-706
    • (2010) Toxicol. In Vitro , vol.24 , pp. 697-706
    • Slunska, Z.1    Gelnarova, E.2    Hammerova, J.3    Taborska, E.4    Slaninova, I.5
  • 158
    • 84867809574 scopus 로고    scopus 로고
    • Necroptosis modulated by autophagy is a predominant form of melanoma cell death induced by sanguilutine
    • Hammerova, J.; Uldrijan, S.; Taborska, E.; Vaculova, A.H.; Slaninova, I. Necroptosis modulated by autophagy is a predominant form of melanoma cell death induced by sanguilutine. Biol. Chem. 2012, 393, 647-658
    • (2012) Biol. Chem , vol.393 , pp. 647-658
    • Hammerova, J.1    Uldrijan, S.2    Taborska, E.3    Vaculova, A.H.4    Slaninova, I.5
  • 160
    • 84855984157 scopus 로고    scopus 로고
    • Study on the alkaloids from the stem of zanthoxylum dissitum
    • Xiao, C.; Yuan, Y.; Ding, Y.Z.; Jin, T.F.; Pei, G. Study on the alkaloids from the stem of zanthoxylum dissitum. Zhong Yao Cai 2011, 34, 551-553
    • (2011) Zhong Yao Cai , vol.34 , pp. 551-553
    • Xiao, C.1    Yuan, Y.2    Ding, Y.Z.3    Jin, T.F.4    Pei, G.5
  • 161
    • 84991010540 scopus 로고    scopus 로고
    • Protopine inhibits heterotypic celladhesion in MDA-MB-231 cells through down-regulation of multi-adhesive factors
    • He, K.; Gao, J.-L. Protopine inhibits heterotypic celladhesion in MDA-MB-231 cells through down-regulation of multi-adhesive factors. Afr. J. Tradit. Complement. Altern. Med. 2014, 11, 415-424
    • (2014) Afr. J. Tradit. Complement. Altern. Med , vol.11 , pp. 415-424
    • He, K.1    Gao, J.-L.2
  • 162
    • 0030773543 scopus 로고    scopus 로고
    • Sanguinarine (Pseudochelerythrine) is a potent inhibitor of NF-κB activation, Iκα phosphorylation, and degradation
    • Chaturvedi, M.M.; Kumar, A.; Darnay, B.G.; Chainy, G.B.; Agarwal, S.; Aggarwal, B.B. Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-κB activation, Iκα phosphorylation, and degradation. J. Biol. Chem. 1997, 272, 30129-30134
    • (1997) J. Biol. Chem , vol.272 , pp. 30129-30134
    • Chaturvedi, M.M.1    Kumar, A.2    Darnay, B.G.3    Chainy, G.B.4    Agarwal, S.5    Aggarwal, B.B.6
  • 164
    • 77954496423 scopus 로고    scopus 로고
    • Formation of human telomeric G-quadruplex structures induced by the quaternary benzophenanthridine alkaloids: Sanguinarine, nitidine, and chelerythrine
    • Yang, S.; Xiang, J.F.; Yang, Q.F.; Li, Q.A.; Zhou, Q.J.; Zhang, X.F.; Tang, Y.L.; Xu, G.Z. Formation of human telomeric G-quadruplex structures induced by the quaternary benzophenanthridine alkaloids: Sanguinarine, nitidine, and chelerythrine. Chin. J. Chem. 2010, 28, 771-780
    • (2010) Chin. J. Chem , vol.28 , pp. 771-780
    • Yang, S.1    Xiang, J.F.2    Yang, Q.F.3    Li, Q.A.4    Zhou, Q.J.5    Zhang, X.F.6    Tang, Y.L.7    Xu, G.Z.8
  • 165
    • 33947402249 scopus 로고    scopus 로고
    • Sanguinarine induces apoptosis of human pancreatic carcinoma AsPC-1 and BxPC-3 cells via modulations in Bcl-2 family proteins
    • Ahsan, H.; Reagan-Shaw, S.; Breur, J.; Ahmad, N. Sanguinarine induces apoptosis of human pancreatic carcinoma AsPC-1 and BxPC-3 cells via modulations in Bcl-2 family proteins. Cancer Lett. 2007, 249, 198-208
    • (2007) Cancer Lett , vol.249 , pp. 198-208
    • Ahsan, H.1    Reagan-Shaw, S.2    Breur, J.3    Ahmad, N.4
  • 166
    • 34547688980 scopus 로고    scopus 로고
    • Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt
    • Han, M.H.; Kim, S.O.; Kim, G.Y.; Kwon, T.K.; Choi, B.T.; Lee, W.H.; Choi, Y.H. Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. Anticancer Drugs 2007, 18, 913-921
    • (2007) Anticancer Drugs , vol.18 , pp. 913-921
    • Han, M.H.1    Kim, S.O.2    Kim, G.Y.3    Kwon, T.K.4    Choi, B.T.5    Lee, W.H.6    Choi, Y.H.7
  • 167
    • 84984797067 scopus 로고    scopus 로고
    • Up-regulation of death receptor 5 and bax translocation is necessary to induce apoptosis by sanguinarine in primary effusion lymphoma
    • Hussain, A.R.; Al-Jomah, N.A.; Siraj, A.K.; Pulicat, M.S.; Al-Hussein, K.A.; Al-Kuraya, K.S.; Uddin, S. Up-regulation of death receptor 5 and bax translocation is necessary to induce apoptosis by sanguinarine in primary effusion lymphoma. Blood 2006, 108, 234B.
    • (2006) Blood , vol.108
    • Hussain, A.R.1    Al-Jomah, N.A.2    Siraj, A.K.3    Pulicat, M.S.4    Al-Hussein, K.A.5    Al-Kuraya, K.S.6    Uddin, S.7
  • 168
    • 84922254798 scopus 로고    scopus 로고
    • Plant alkaloid chelerythrine induced aggregation of human telomere sequence-A unique mode of association between a small molecule and a quadruplex
    • Ghosh, S.; Jana, J.; Kar, R.K.; Chatterjee, S.; Dasgupta, D. Plant alkaloid chelerythrine induced aggregation of human telomere sequence-A unique mode of association between a small molecule and a quadruplex. Biochemistry 2015, 54, 974-986
    • (2015) Biochemistry , vol.54 , pp. 974-986
    • Ghosh, S.1    Jana, J.2    Kar, R.K.3    Chatterjee, S.4    Dasgupta, D.5
  • 169
    • 0242654822 scopus 로고    scopus 로고
    • Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids
    • Barreto, M.C.; Pinto, R.E.; Arrabaca, J.D.; Pavao, M.L. Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids. Toxicol. Lett. 2003, 146, 37-47
    • (2003) Toxicol. Lett , vol.146 , pp. 37-47
    • Barreto, M.C.1    Pinto, R.E.2    Arrabaca, J.D.3    Pavao, M.L.4
  • 171
    • 3843066800 scopus 로고    scopus 로고
    • Chelerythrine and other benzophenanthridine alkaloids block the human P2X7 receptor
    • Shemon, A.N.; Sluyter, R.; Conigrave, A.D.; Wiley, J.S. Chelerythrine and other benzophenanthridine alkaloids block the human P2X7 receptor. Br. J. Pharmacol. 2004, 142, 1015-1019
    • (2004) Br. J. Pharmacol , vol.142 , pp. 1015-1019
    • Shemon, A.N.1    Sluyter, R.2    Conigrave, A.D.3    Wiley, J.S.4
  • 172
    • 79955619444 scopus 로고    scopus 로고
    • Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase
    • Tan, I.; Lai, J.; Yong, J.; Li, S.F.Y.; Leung, T. Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase. FEBS Lett. 2011, 585, 1260-1268
    • (2011) FEBS Lett , vol.585 , pp. 1260-1268
    • Tan, I.1    Lai, J.2    Yong, J.3    Li, S.F.Y.4    Leung, T.5
  • 173
    • 79960248825 scopus 로고    scopus 로고
    • Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell
    • Zhang, Z.-F.; Guo, Y.; Zhang, J.-B.; Wei, X.-H. Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell. Arch. Pharm. Res. 2011, 34, 791-800
    • (2011) Arch. Pharm. Res. , vol.34 , pp. 791-800
    • Zhang, Z.-F.1    Guo, Y.2    Zhang, J.-B.3    Wei, X.-H.4
  • 174
    • 0034932996 scopus 로고    scopus 로고
    • Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells
    • Slaninová, I.; Táborská, E.; Bochořáková, H.; Slanina, J. Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells. Cell Biol. Toxicol. 2001, 17, 51-63
    • (2001) Cell Biol. Toxicol , vol.17 , pp. 51-63
    • Slaninová, I.1    Táborská, E.2    Bochořáková, H.3    Slanina, J.4
  • 175
    • 48749107430 scopus 로고    scopus 로고
    • Protective effects of protopine on hydrogen peroxide-induced oxidative injury of PC12 cells via Ca2+ antagonism and antioxidant mechanisms
    • Xiao, X.; Liu, J.; Hu, J.; Zhu, X.; Yang, H.; Wang, C.; Zhang, Y. Protective effects of protopine on hydrogen peroxide-induced oxidative injury of PC12 cells via Ca2+ antagonism and antioxidant mechanisms. Eur. J. Pharmacol. 2008, 591, 21-27
    • (2008) Eur. J. Pharmacol. , vol.591 , pp. 21-27
    • Xiao, X.1    Liu, J.2    Hu, J.3    Zhu, X.4    Yang, H.5    Wang, C.6    Zhang, Y.7
  • 176
    • 0342871998 scopus 로고    scopus 로고
    • Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores
    • Schmeller, T.; Latz-Brüning, B.; Wink, M. Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores. Phytochemistry 1997, 44, 257-266
    • (1997) Phytochemistry , vol.44 , pp. 257-266
    • Schmeller, T.1    Latz-Brüning, B.2    Wink, M.3
  • 177
    • 18644363955 scopus 로고    scopus 로고
    • Inhibitory activity on binding of specific ligands to the human angiotensin II AT1 and endothelin 1 ETA receptors: Bioactive benzo[c]phenanthridine alkaloids from the root of Bocconia frutescens
    • Caballero-George, C.; Vanderheyden, P.M.; Apers, S.; van den Heuvel, H.; Solis, P.N.; Gupta, M.P.; Claeys, M.; Pieters, L.; Vauquelin, G.; Vlietinck, A.J. Inhibitory activity on binding of specific ligands to the human angiotensin II AT1 and endothelin 1 ETA receptors: Bioactive benzo[c]phenanthridine alkaloids from the root of Bocconia frutescens. Planta Med. 2002, 68, 770-775
    • (2002) Planta Med. , vol.68 , pp. 770-775
    • Caballero-George, C.1    Vanderheyden, P.M.2    Apers, S.3    Van Den Heuvel, H.4    Solis, P.N.5    Gupta, M.P.6    Claeys, M.7    Pieters, L.8    Vauquelin, G.9    Vlietinck, A.J.10
  • 180
    • 33747374999 scopus 로고    scopus 로고
    • Effects of protopine on intracellular calcium and the PKC activity of rat aorta smooth muscle
    • Li, B.; Wu, Q.; Shi, J.-S.; Sun, A.-S.; Huang, X.-N. Effects of protopine on intracellular calcium and the PKC activity of rat aorta smooth muscle. Sheng Li Xue Bao 2005, 57, 240-246
    • (2005) Sheng Li Xue Bao , vol.57 , pp. 240-246
    • Li, B.1    Wu, Q.2    Shi, J.-S.3    Sun, A.-S.4    Huang, X.-N.5
  • 181
    • 0018567554 scopus 로고
    • Sanguinarine: A positive inotropic alkaloid which inhibits cardiac Na+,K+-ATPase
    • Seifen, E.; Adams, R.J.; Riemer, R.K. Sanguinarine: A positive inotropic alkaloid which inhibits cardiac Na+,K+-ATPase. Eur. J. Pharmacol. 1979, 60, 373-377
    • (1979) Eur. J. Pharmacol , vol.60 , pp. 373-377
    • Seifen, E.1    Adams, R.J.2    Riemer, R.K.3
  • 182
    • 0034092876 scopus 로고    scopus 로고
    • Electrophysiological effects of protopine in cardiac myocytes: Inhibition of multiple cation channel currents
    • Song, L.S.; Ren, G.J.; Chen, Z.L.; Chen, Z.H.; Zhou, Z.N.; Cheng, H. Electrophysiological effects of protopine in cardiac myocytes: Inhibition of multiple cation channel currents. Br. J. Pharmacol. 2000, 129, 893-900
    • (2000) Br. J. Pharmacol , vol.129 , pp. 893-900
    • Song, L.S.1    Ren, G.J.2    Chen, Z.L.3    Chen, Z.H.4    Zhou, Z.N.5    Cheng, H.6
  • 183
    • 55249085151 scopus 로고    scopus 로고
    • Effect of α-allocryptopine on transient outward potassium current in rabbit ventricular myocytes
    • Li, Y.; Wang, S.; Liu, Y.; Li, Z.; Yang, X.; Wang, H.; Wen, Y.; Chen, Y. Effect of α-allocryptopine on transient outward potassium current in rabbit ventricular myocytes. Cardiology 2008, 111, 229-236
    • (2008) Cardiology , vol.111 , pp. 229-236
    • Li, Y.1    Wang, S.2    Liu, Y.3    Li, Z.4    Yang, X.5    Wang, H.6    Wen, Y.7    Chen, Y.8
  • 184
    • 84984848023 scopus 로고
    • Comparative study of the anti-arrhythmic action of the alkaloid a-allocryptopine with quinidine
    • Akbarov, Z.S.; Aliev, K.; Sultanov, M.B. Comparative study of the anti-arrhythmic action of the alkaloid a-allocryptopine with quinidine. Dokl. Akad. Nauk Uzb. 1972, 29, 38.
    • (1972) Dokl. Akad. Nauk Uzb , vol.29
    • Akbarov, Z.S.1    Aliev, K.2    Sultanov, M.B.3
  • 185
    • 0034776026 scopus 로고    scopus 로고
    • Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in Cardiac myocytes
    • Yamamoto, S.; Seta, K.; Morisco, C.; Vatner, S.F.; Sadoshima, J. Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in Cardiac myocytes. J. Mol. Cell. Cardiol. 2001, 33, 1829-1848
    • (2001) J. Mol. Cell. Cardiol , vol.33 , pp. 1829-1848
    • Yamamoto, S.1    Seta, K.2    Morisco, C.3    Vatner, S.F.4    Sadoshima, J.5
  • 186
    • 84863289787 scopus 로고    scopus 로고
    • Protopine reduces the inflammatory activity of lipopolysaccharide-stimulated murine macrophages
    • Bae, D.S.; Kim, Y.H.; Pan, C.-H.; Nho, C.W.; Samdan, J.; Yansan, J.; Lee, J.K. Protopine reduces the inflammatory activity of lipopolysaccharide-stimulated murine macrophages. BMB Rep. 2012, 45, 108
    • (2012) BMB Rep , vol.45
    • Bae, D.S.1    Kim, Y.H.2    Pan, C.-H.3    Nho, C.W.4    Samdan, J.5    Yansan, J.6    Lee, J.K.7
  • 187
    • 79955469916 scopus 로고    scopus 로고
    • Effects of chelerythrine, a specific inhibitor of cyclooxygenase-2, on acute inflammation in mice
    • Niu, X.-F.; Zhou, P.; Li, W.-F.; Xu, H.-B. Effects of chelerythrine, a specific inhibitor of cyclooxygenase-2, on acute inflammation in mice. Fitoterapia 2011, 82, 620-625
    • (2011) Fitoterapia , vol.82 , pp. 620-625
    • Niu, X.-F.1    Zhou, P.2    Li, W.-F.3    Xu, H.-B.4
  • 188
    • 0029829338 scopus 로고    scopus 로고
    • Benzophenanthridine alkaloids of chelidonium majus; I. Inhibition of 5- and 12-lipoxygenase by a non-redox mechanism
    • Vavreckova, C.; Gawlik, I.; Muller, K. Benzophenanthridine alkaloids of chelidonium majus; I. Inhibition of 5- and 12-lipoxygenase by a non-redox mechanism. Planta Med. 1996, 62, 397-401
    • (1996) Planta Med , vol.62 , pp. 397-401
    • Vavreckova, C.1    Gawlik, I.2    Muller, K.3
  • 189
    • 0035512895 scopus 로고    scopus 로고
    • Investigation of the inhibitory effects of chelerythrine chloride on the translocation of the protein kinase c βi, βii, ζ in human neutrophils
    • Siomboing, X.; Gressier, B.; Dine, T.; Brunet, C.; Luyckx, M.; Cazin, M.; Cazin, J.-C. Investigation of the inhibitory effects of chelerythrine chloride on the translocation of the protein kinase c βi, βii, ζ in human neutrophils. IL Farmaco 2001, 56, 859-865
    • (2001) IL Farmaco , vol.56 , pp. 859-865
    • Siomboing, X.1    Gressier, B.2    Dine, T.3    Brunet, C.4    Luyckx, M.5    Cazin, M.6    Cazin, J.-C.7
  • 190
    • 37749037498 scopus 로고    scopus 로고
    • Conventional protein kinase c isoenzymes undergo dephosphorylation in neutrophil-like HL-60 cells treated by chelerythrine or sanguinarine
    • Vrba, J.; Dvorak, Z.; Ulrichova, J.; Modriansky, M. Conventional protein kinase c isoenzymes undergo dephosphorylation in neutrophil-like HL-60 cells treated by chelerythrine or sanguinarine. Cell Biol. Toxicol. 2008, 24, 39-53
    • (2008) Cell Biol. Toxicol , vol.24 , pp. 39-53
    • Vrba, J.1    Dvorak, Z.2    Ulrichova, J.3    Modriansky, M.4
  • 191
    • 0027156167 scopus 로고
    • Impairment of function in aging neutrophils is associated with apoptosis
    • Whyte, M.; Meagher, L.C.; MacDermot, J.; Haslett, C. Impairment of function in aging neutrophils is associated with apoptosis. J. Immunol. 1993, 150, 5124-5134
    • (1993) J. Immunol , vol.150 , pp. 5124-5134
    • Whyte, M.1    Meagher, L.C.2    Macdermot, J.3    Haslett, C.4
  • 192
    • 0026465484 scopus 로고
    • Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes
    • Haslett, C. Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes. Clin. Sci. 1992, 83, 639-648
    • (1992) Clin. Sci , vol.83 , pp. 639-648
    • Haslett, C.1
  • 193
    • 0025838036 scopus 로고
    • Neutrophil apoptosis and clearance from neonatal lungs
    • Grigg, J.; Silverman, M.; Savill, J.; Sarraf, C.; Haslett, C. Neutrophil apoptosis and clearance from neonatal lungs. Lancet 1991, 338, 720-722
    • (1991) Lancet , vol.338 , pp. 720-722
    • Grigg, J.1    Silverman, M.2    Savill, J.3    Sarraf, C.4    Haslett, C.5
  • 194
    • 0026668586 scopus 로고
    • Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis
    • Savill, J.; Smith, J.; Sarraf, C.; Ren, Y.; Abbott, F.; Rees, A. Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis. Kidney Int. 1992, 42, 924-936
    • (1992) Kidney Int , vol.42 , pp. 924-936
    • Savill, J.1    Smith, J.2    Sarraf, C.3    Ren, Y.4    Abbott, F.5    Rees, A.6
  • 195
    • 0034203547 scopus 로고    scopus 로고
    • Chelerythrine chloride induces rapid polymorphonuclear leukocyte apoptosis through activation of caspase-3
    • Sweeney, J.F.; Nguyen, P.K.; Atkins, K.B.; Hinshaw, D.B. Chelerythrine chloride induces rapid polymorphonuclear leukocyte apoptosis through activation of caspase-3. Shock 2000, 13, 464-471
    • (2000) Shock , vol.13 , pp. 464-471
    • Sweeney, J.F.1    Nguyen, P.K.2    Atkins, K.B.3    Hinshaw, D.B.4
  • 196
    • 0028231065 scopus 로고
    • Adhesion molecules and inflammatory injury
    • Albelda, S.M.; Smith, C.W.; Ward, P. Adhesion molecules and inflammatory injury. FASEB J. 1994, 8, 504-512
    • (1994) FASEB J , vol.8 , pp. 504-512
    • Albelda, S.M.1    Smith, C.W.2    Ward, P.3
  • 197
    • 0034946691 scopus 로고    scopus 로고
    • Important roles for l-selectin and icam-1 in the development of allergic airway inflammation in asthma
    • Tang, M.; Fiscus, L. Important roles for l-selectin and icam-1 in the development of allergic airway inflammation in asthma. Pulm. Pharmacol. Ther. 2001, 14, 203-210
    • (2001) Pulm. Pharmacol. Ther. , vol.14 , pp. 203-210
    • Tang, M.1    Fiscus, L.2
  • 198
    • 84899110414 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1 as a drug target in asthma and rhinitis
    • Mukhopadhyay, S.; Malik, P.; Arora, S.K.; Mukherjee, T.K. Intercellular adhesion molecule-1 as a drug target in asthma and rhinitis. Respirology 2014, 19, 508-513
    • (2014) Respirology , vol.19 , pp. 508-513
    • Mukhopadhyay, S.1    Malik, P.2    Arora, S.K.3    Mukherjee, T.K.4
  • 199
    • 77953632742 scopus 로고    scopus 로고
    • Interleukin-1β induces ICAM-1 expression enhancing leukocyte adhesion in human rheumatoid arthritis synovial fibroblasts: Involvement of erk, JNK, AP-1, and NF-κB
    • Yang, C.M.; Luo, S.F.; Hsieh, H.L.; Chi, P.L.; Lin, C.C.; Wu, C.C.; Hsiao, L.D. Interleukin-1β induces ICAM-1 expression enhancing leukocyte adhesion in human rheumatoid arthritis synovial fibroblasts: Involvement of erk, JNK, AP-1, and NF-κB. J. Cell. Physiol. 2010, 224, 516-526
    • (2010) J. Cell. Physiol , vol.224 , pp. 516-526
    • Yang, C.M.1    Luo, S.F.2    Hsieh, H.L.3    Chi, P.L.4    Lin, C.C.5    Wu, C.C.6    Hsiao, L.D.7
  • 200
    • 33751292023 scopus 로고    scopus 로고
    • Detailed analysis of the cell infiltrate and the expression of mediators of synovial inflammation and joint destruction in the synovium of patients with psoriatic arthritis: Implications for treatment
    • Van Kuijk, A.W.; Reinders-Blankert, P.; Smeets, T.J.; Dijkmans, B.A.; Tak, P.P. Detailed analysis of the cell infiltrate and the expression of mediators of synovial inflammation and joint destruction in the synovium of patients with psoriatic arthritis: Implications for treatment. Ann. Rheum. Dis. 2006, 65, 1551-1557
    • (2006) Ann. Rheum. Dis , vol.65 , pp. 1551-1557
    • Van Kuijk, A.W.1    Reinders-Blankert, P.2    Smeets, T.J.3    Dijkmans, B.A.4    Tak, P.P.5
  • 203
    • 84921694332 scopus 로고    scopus 로고
    • Synergistic antimicrobial activity of combinations of sanguinarine and edta with vancomycin against multidrug resistant bacteria
    • Hamoud, R.; Reichling, J.; Wink, M. Synergistic antimicrobial activity of combinations of sanguinarine and edta with vancomycin against multidrug resistant bacteria. Drug Metab. Lett. 2014, 8, 119-128
    • (2014) Drug Metab. Lett , vol.8 , pp. 119-128
    • Hamoud, R.1    Reichling, J.2    Wink, M.3
  • 204
    • 0021909905 scopus 로고
    • Comparative in vitro activity of sanguinarine against oral microbial isolates
    • Dzink, J.L.; Socransky, S.S. Comparative in vitro activity of sanguinarine against oral microbial isolates. Antimicrob. Agents Chemother. 1985, 27, 663-665
    • (1985) Antimicrob. Agents Chemother , vol.27 , pp. 663-665
    • Dzink, J.L.1    Socransky, S.S.2
  • 205
    • 77954704743 scopus 로고    scopus 로고
    • Helicobacter pylori treatment in the era of increasing antibiotic resistance
    • Graham, D.Y.; Fischbach, L. Helicobacter pylori treatment in the era of increasing antibiotic resistance. Gut 2010, 59, 1143-1153
    • (2010) Gut , vol.59 , pp. 1143-1153
    • Graham, D.Y.1    Fischbach, L.2
  • 206
    • 0344406943 scopus 로고    scopus 로고
    • In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis
    • Mahady, G.B.; Pendland, S.L.; Stoia, A.; Chadwick, L.R. In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis. Phytother. Res. 2003, 17, 217-221
    • (2003) Phytother. Res , vol.17 , pp. 217-221
    • Mahady, G.B.1    Pendland, S.L.2    Stoia, A.3    Chadwick, L.R.4
  • 207
    • 0036136769 scopus 로고    scopus 로고
    • The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis
    • Newton, S.M.; Lau, C.; Gurcha, S.S.; Besra, G.S.; Wright, C.W. The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis. J. Ethnopharmacol. 2002, 79, 57-67
    • (2002) J. Ethnopharmacol , vol.79 , pp. 57-67
    • Newton, S.M.1    Lau, C.2    Gurcha, S.S.3    Besra, G.S.4    Wright, C.W.5
  • 208
    • 0017410779 scopus 로고
    • Synthesis and properties of praziquantel, a novel broad spectrum anthelmintic with excellent activity against schistosomes and cestodes
    • Seubert, J.; Pohlke, R.; Loebich, F. Synthesis and properties of praziquantel, a novel broad spectrum anthelmintic with excellent activity against schistosomes and cestodes. Experientia 1977, 33, 1036-1037
    • (1977) Experientia , vol.33 , pp. 1036-1037
    • Seubert, J.1    Pohlke, R.2    Loebich, F.3
  • 210
    • 84872405303 scopus 로고    scopus 로고
    • Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis
    • Zhang, S.-M.; Coultas, K.A. Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis. Int. J. Parasitol. Drugs Drug Resist. 2013, 3, 28-34
    • (2013) Int. J. Parasitol. Drugs Drug Resist. , vol.3 , pp. 28-34
    • Zhang, S.-M.1    Coultas, K.A.2
  • 212
    • 36849094328 scopus 로고    scopus 로고
    • Manifestations, diagnosis, and treatment of strongyloides stercoralis infection
    • Segarra-Newnham, M. Manifestations, diagnosis, and treatment of strongyloides stercoralis infection. Ann. Pharmacother. 2007, 41, 1992-2001
    • (2007) Ann. Pharmacother , vol.41 , pp. 1992-2001
    • Segarra-Newnham, M.1
  • 213
    • 0036498042 scopus 로고    scopus 로고
    • Assay of nematocidal activity of isoquinoline alkaloids using third-stage larvae of Strongyloides ratti and S
    • Satou, T.; Koga, M.; Matsuhashi, R.; Koike, K.; Tada, I.; Nikaido, T. Assay of nematocidal activity of isoquinoline alkaloids using third-stage larvae of Strongyloides ratti and S. Venezuelensis. Vet. Parasitol. 2002, 104, 131-138
    • (2002) Venezuelensis. Vet. Parasitol. , vol.104 , pp. 131-138
    • Satou, T.1    Koga, M.2    Matsuhashi, R.3    Koike, K.4    Tada, I.5    Nikaido, T.6
  • 214
    • 33745276598 scopus 로고    scopus 로고
    • Five new species of Dactylogyrus (Monogenea) from cyprimd fishes in Thailand
    • Kaewviyudth, S.; Chinabut, S. Five new species of Dactylogyrus (Monogenea) from cyprimd fishes in Thailand. Asian Fish. Sci. 1999, 12, 391-399.
    • (1999) Asian Fish. Sci , vol.12 , pp. 391-399
    • Kaewviyudth, S.1    Chinabut, S.2
  • 215
    • 77954623531 scopus 로고    scopus 로고
    • In vivo anthelmintic activity of five alkaloids from Macleaya microcarpa (Maxim.) fedde against Dactylogyrus intermedius in Carassius auratus
    • Wang, G.X.; Zhou, Z.; Jiang, D.X.; Han, J.; Wang, J.F.; Zhao, L.W.; Li, J. In vivo anthelmintic activity of five alkaloids from Macleaya microcarpa (Maxim.) fedde against Dactylogyrus intermedius in Carassius auratus. Vet. Parasitol. 2010, 171, 305-313
    • (2010) Vet. Parasitol , vol.171 , pp. 305-313
    • Wang, G.X.1    Zhou, Z.2    Jiang, D.X.3    Han, J.4    Wang, J.F.5    Zhao, L.W.6    Li, J.7
  • 216
    • 1842870834 scopus 로고    scopus 로고
    • Inhibitory effect of isoquinoline alkaloids on movement of second-stage larvae of Toxocara canis
    • Satou, T.; Akao, N.; Matsuhashi, R.; Koike, K.; Fujita, K.; Nikaido, T. Inhibitory effect of isoquinoline alkaloids on movement of second-stage larvae of Toxocara canis. Biol. Pharm. Bull. 2002, 25, 1651-1654
    • (2002) Biol. Pharm. Bull , vol.25 , pp. 1651-1654
    • Satou, T.1    Akao, N.2    Matsuhashi, R.3    Koike, K.4    Fujita, K.5    Nikaido, T.6
  • 217
    • 23244440510 scopus 로고    scopus 로고
    • Identification of sanguinarine as a novel HIV protease inhibitor from high-throughput screening of 2000 drugs and natural products with a cell-based assay
    • Cheng, T.J.; Goodsell, D.S.; Kan, C.C. Identification of sanguinarine as a novel HIV protease inhibitor from high-throughput screening of 2000 drugs and natural products with a cell-based assay. Lett. Drug Des. Discov. 2005, 2, 364-371
    • (2005) Lett. Drug Des. Discov. , vol.2 , pp. 364-371
    • Cheng, T.J.1    Goodsell, D.S.2    Kan, C.C.3
  • 219
    • 77951573322 scopus 로고    scopus 로고
    • Antiplasmodial agents from the bhutanese medicinal plant Corydalis calliantha
    • Wangchuk, P.; Bremner, J.B.; Rattanajak, R.; Kamchonwongpaisan, S. Antiplasmodial agents from the bhutanese medicinal plant Corydalis calliantha. Phytother. Res. 2010, 24, 481-485
    • (2010) Phytother. Res , vol.24 , pp. 481-485
    • Wangchuk, P.1    Bremner, J.B.2    Rattanajak, R.3    Kamchonwongpaisan, S.4
  • 220
    • 55249117688 scopus 로고    scopus 로고
    • Alkaloids induce programmed cell death in bloodstream forms of trypanosomes (Trypanosoma b. Brucei)
    • Rosenkranz, V.; Wink, M. Alkaloids induce programmed cell death in bloodstream forms of trypanosomes (Trypanosoma b. brucei). Molecules 2008, 13, 2462-2473
    • (2008) Molecules , vol.13 , pp. 2462-2473
    • Rosenkranz, V.1    Wink, M.2
  • 221
    • 69949111548 scopus 로고    scopus 로고
    • Antifungal activity of the benzo[c]phenanthridine alkaloids from Chelidonium majus Linn against resistant clinical yeast isolates
    • Meng, F.; Zuo, G.; Hao, X.; Wang, G.; Xiao, H.; Zhang, J.; Xu, G. Antifungal activity of the benzo[c]phenanthridine alkaloids from Chelidonium majus Linn against resistant clinical yeast isolates. J. Ethnopharmacol. 2009, 125, 494-496
    • (2009) J. Ethnopharmacol , vol.125 , pp. 494-496
    • Meng, F.1    Zuo, G.2    Hao, X.3    Wang, G.4    Xiao, H.5    Zhang, J.6    Xu, G.7
  • 222
    • 84942297421 scopus 로고    scopus 로고
    • Plant alkaloids as drug leads for Alzheimer’s disease
    • Pong Ng, Y.; Tsun Or, T.C.; Ip, N.Y. Plant alkaloids as drug leads for Alzheimer’s disease. Neurochem. Int. 2015, 89, 260-270.
    • (2015) Neurochem. Int , vol.89 , pp. 260-270
    • Pong Ng, Y.1    Tsun Or, T.C.2    Ip, N.Y.3
  • 223
  • 225
    • 14644411762 scopus 로고    scopus 로고
    • Discovery of drug candidates from some turkish plants and conservation of biodiversity
    • Sener, B.; Orhan, İ. Discovery of drug candidates from some turkish plants and conservation of biodiversity. Pure Appl. Chem. 2005, 77, 53-64
    • (2005) Pure Appl. Chem , vol.77 , pp. 53-64
    • Sener, B.1    Orhan, İ.2
  • 226
    • 84937484796 scopus 로고    scopus 로고
    • Selective targeting of PPARΓ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency
    • Zheng, W.; Qiu, L.; Wang, R.; Feng, X.; Han, Y.; Zhu, Y.; Chen, D.; Liu, Y.; Jin, L.; Li, Y. Selective targeting of PPARΓ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency. Sci. Rep. 2015, 5, 12222
    • (2015) Sci. Rep , vol.5
    • Zheng, W.1    Qiu, L.2    Wang, R.3    Feng, X.4    Han, Y.5    Zhu, Y.6    Chen, D.7    Liu, Y.8    Jin, L.9    Li, Y.10
  • 227
    • 24944439400 scopus 로고    scopus 로고
    • Regulation of glutamate level in rat brain through activation of glutamate dehydrogenase by Corydalis ternata
    • Lee, K.H.; Huh, J.; Choi, M.; Yoon, S.Y.; Yang, S.; Hong, H.; Cho, S. Regulation of glutamate level in rat brain through activation of glutamate dehydrogenase by Corydalis ternata. Exp. Mol. Med. 2005, 37, 371-377
    • (2005) Exp. Mol. Med , vol.37 , pp. 371-377
    • Lee, K.H.1    Huh, J.2    Choi, M.3    Yoon, S.Y.4    Yang, S.5    Hong, H.6    Cho, S.7
  • 228
    • 33646905684 scopus 로고    scopus 로고
    • Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models
    • Xu, L.-F.; Chu, W.-J.; Qing, X.-Y.; Li, S.; Wang, X.-S.; Qing, G.-W.; Fei, J.; Guo, L.-H. Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models. Neuropharmacology 2006, 50, 934-940
    • (2006) Neuropharmacology , vol.50 , pp. 934-940
    • Xu, L.-F.1    Chu, W.-J.2    Qing, X.-Y.3    Li, S.4    Wang, X.-S.5    Qing, G.-W.6    Fei, J.7    Guo, L.-H.8
  • 229
    • 34447591862 scopus 로고
    • Ueber Das Protopin. Naunyn Schmiedebergs Arch
    • Engel, R. Ueber Das Protopin. Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmakol. 1890, 27, 419-431
    • (1890) Exp. Pathol. Pharmakol , vol.27 , pp. 419-431
    • Engel, R.1
  • 230
    • 84984796987 scopus 로고
    • Studies on the Alkaloids of Macleya cordata R
    • Goto, K.; Oda, R. Studies on the Alkaloids of Macleya cordata R. J. Pharm. Soc. Jpn. 1949, 69, 307
    • (1949) J. Pharm. Soc. Jpn , vol.69
    • Goto, K.1    Oda, R.2
  • 231
    • 0030863004 scopus 로고    scopus 로고
    • Effects of allocryptopine, an alkaloid isolated from glaucium arabicum on rat isolated ileum and urinary bladder
    • Abu-Ghalyun, Y.; Masalmeh, A.; Al-Khalil, S. Effects of allocryptopine, an alkaloid isolated from glaucium arabicum on rat isolated ileum and urinary bladder. Gen. Pharmacol. Vasc. Syst. 1997, 29, 621-623
    • (1997) Gen. Pharmacol. Vasc. Syst. , vol.29 , pp. 621-623
    • Abu-Ghalyun, Y.1    Masalmeh, A.2    Al-Khalil, S.3
  • 232
    • 0023722156 scopus 로고
    • In vitro study of the anticholinergic and antihistaminic activities of protopine and some derivatives
    • Üstünes, L.; Laekeman, G.M.; Gözler, B.; Vlietinck, A.J.; Özer, A.; Herman, A.G. In vitro study of the anticholinergic and antihistaminic activities of protopine and some derivatives. J. Nat. Prod. 1988, 51, 1021-1022
    • (1988) J. Nat. Prod , vol.51 , pp. 1021-1022
    • Üstünes, L.1    Laekeman, G.M.2    Gözler, B.3    Vlietinck, A.J.4    Özer, A.5    Herman, A.G.6
  • 235
    • 0001882052 scopus 로고    scopus 로고
    • Organic acids as feed additives for young pigs: Nutritional and gastrointestinal effects
    • Roth, R.; Kirchgessner, M. Organic acids as feed additives for young pigs: Nutritional and gastrointestinal effects. J. Anim. Feed Sci. 1998, 7, 25-33.
    • (1998) J. Anim. Feed Sci , vol.7 , pp. 25-33
    • Roth, R.1    Kirchgessner, M.2
  • 236
    • 77957160664 scopus 로고    scopus 로고
    • Sanguinarine does not influence availability or metabolism of tryptophan in pigs
    • Blank, R.; Muller-Siegwardt, B.; Wolffram, S. Sanguinarine does not influence availability or metabolism of tryptophan in pigs. Livest. Sci. 2010, 134, 24-26
    • (2010) Livest. Sci , vol.134 , pp. 24-26
    • Blank, R.1    Muller-Siegwardt, B.2    Wolffram, S.3
  • 238
    • 84921477165 scopus 로고    scopus 로고
    • The effect of a natural feed additive (Macleaya cordata), containing sanguinarine, on the performance and health status of weaning pigs
    • Kantas, D.; Papatsiros, V.G.; Tassis, P.D.; Athanasiou, L.V.; Tzika, E.D. The effect of a natural feed additive (Macleaya cordata), containing sanguinarine, on the performance and health status of weaning pigs. Anim. Sci. J. 2015, 86, 92-98
    • (2015) Anim. Sci. J , vol.86 , pp. 92-98
    • Kantas, D.1    Papatsiros, V.G.2    Tassis, P.D.3    Athanasiou, L.V.4    Tzika, E.D.5
  • 240
    • 67650080148 scopus 로고    scopus 로고
    • Preliminary assessment of dietary supplementation of sangrovit® on red tilapia (Oreochromis niloticus) growth performance and health
    • Rawling, M.D.; Merrifield, D.L.; Davies, S.J. Preliminary assessment of dietary supplementation of sangrovit® on red tilapia (Oreochromis niloticus) growth performance and health. Aquaculture 2009, 294, 118-122
    • (2009) Aquaculture , vol.294 , pp. 118-122
    • Rawling, M.D.1    Merrifield, D.L.2    Davies, S.J.3
  • 241
    • 84883719109 scopus 로고    scopus 로고
    • Effect of sanguinarine in drinking water on salmonella control and the expression of immune cells in peripheral blood and intestinal mucosa of broilers
    • Pickler, L.; Beirão, B.C.; Hayashi, R.M.; Durau, J.F.; Lourenço, M.C.; Caron, L.F.; Santin, E. Effect of sanguinarine in drinking water on salmonella control and the expression of immune cells in peripheral blood and intestinal mucosa of broilers. J. Appl. Poult. Res. 2013, 22, 430-438
    • (2013) J. Appl. Poult. Res , vol.22 , pp. 430-438
    • Pickler, L.1    Beirão, B.C.2    Hayashi, R.M.3    Durau, J.F.4    Lourenço, M.C.5    Caron, L.F.6    Santin, E.7
  • 242
    • 84888225774 scopus 로고    scopus 로고
    • Effects of quaternary benzo[c]phenanthridine alkaloids on growth performance, shedding of organisms, and gastrointestinal tract integrity in pigs inoculated with multidrug-resistant Salmonella spp
    • Robbins, R.C.; Artuso-Ponte, V.C.; Moeser, A.J.; Morrow, W.E.M.; Spears, J.W.; Gebreyes, W.A. Effects of quaternary benzo[c]phenanthridine alkaloids on growth performance, shedding of organisms, and gastrointestinal tract integrity in pigs inoculated with multidrug-resistant Salmonella spp.. Am. J. Vet. Res. 2013, 74, 1530-1535
    • (2013) Am. J. Vet. Res. , vol.74 , pp. 1530-1535
    • Robbins, R.C.1    Artuso-Ponte, V.C.2    Moeser, A.J.3    Morrow, W.E.M.4    Spears, J.W.5    Gebreyes, W.A.6
  • 243
    • 84874525074 scopus 로고    scopus 로고
    • A review of equine sarcoid
    • Taylor, S.; Haldorson, G. A review of equine sarcoid. Equine Vet. Educ. 2013, 25, 210-216
    • (2013) Equine Vet. Educ , vol.25 , pp. 210-216
    • Taylor, S.1    Haldorson, G.2
  • 246
    • 84906258422 scopus 로고    scopus 로고
    • Owners’ perception of the efficacy of newmarket bloodroot ointment in treating equine sarcoids
    • Wilford, S.; Woodward, E.; Dunkel, B. Owners’ perception of the efficacy of newmarket bloodroot ointment in treating equine sarcoids. Can. Vet. J. 2014, 55, 683-686
    • (2014) Can. Vet. J , vol.55 , pp. 683-686
    • Wilford, S.1    Woodward, E.2    Dunkel, B.3
  • 247
    • 79961064151 scopus 로고    scopus 로고
    • Consequences of intratumoral injection of a herbal preparation containing blood root (Sanguinaria canadensis) extract in two dogs
    • Childress, M.O.; Burgess, R.C.; Holland, C.H.; Gelb, H.R. Consequences of intratumoral injection of a herbal preparation containing blood root (Sanguinaria canadensis) extract in two dogs. J. Am. Vet. Med. Assoc. 2011, 239, 374-379
    • (2011) J. Am. Vet. Med. Assoc , vol.239 , pp. 374-379
    • Childress, M.O.1    Burgess, R.C.2    Holland, C.H.3    Gelb, H.R.4
  • 249
    • 0032609275 scopus 로고    scopus 로고
    • Leukoplakia of the maxillary vestibule-An association with viadent? Oral Surg
    • Damm, D.D.; Curran, A.; White, D.K.; Drummond, J.E. Leukoplakia of the maxillary vestibule-An association with viadent? Oral Surg. Oral Med. 1999, 87, 61-66
    • (1999) Oral Med , vol.87 , pp. 61-66
    • Damm, D.D.1    Curran, A.2    White, D.K.3    Drummond, J.E.4
  • 250
    • 84984823464 scopus 로고    scopus 로고
    • The flow of saliva and its influence on the movement, deposition and removal of drugs administered to the oral cavity
    • Weatherell, J.A.; Robinson, C.; Rathbone, M. The flow of saliva and its influence on the movement, deposition and removal of drugs administered to the oral cavity. Drugs Pharm. Sci. 1996, 74, 157-189.
    • (1996) Drugs Pharm. Sci , vol.74 , pp. 157-189
    • Weatherell, J.A.1    Robinson, C.2    Rathbone, M.3
  • 252
    • 0034171320 scopus 로고    scopus 로고
    • Sanguinaria-associated oral leukoplakia: Comparison with other benign and dysplastic leukoplakic lesions
    • Eversole, L.R.; Eversole, G.M.; Kopcik, J. Sanguinaria-associated oral leukoplakia: Comparison with other benign and dysplastic leukoplakic lesions. Oral Surg. Oral Med. 2000, 89, 455-464
    • (2000) Oral Surg. Oral Med , vol.89 , pp. 455-464
    • Eversole, L.R.1    Eversole, G.M.2    Kopcik, J.3
  • 253
    • 0035522631 scopus 로고    scopus 로고
    • Sanguinaria-related leukoplakia: Epidemiologic and clinicopathologic features of a recently described entity
    • Allen, C.L.; Loudon, J.; Mascarenhas, A.K. Sanguinaria-related leukoplakia: Epidemiologic and clinicopathologic features of a recently described entity. Gen. Dent. 2001, 49, 608-614
    • (2001) Gen. Dent , vol.49 , pp. 608-614
    • Allen, C.L.1    Loudon, J.2    Mascarenhas, A.K.3
  • 254
    • 0033608561 scopus 로고    scopus 로고
    • Antibacterial agents in the control of supragingival plaque-A review
    • Eley, B.M. Antibacterial agents in the control of supragingival plaque-A review. Br. Dent. J. 1999, 186, 286-296
    • (1999) Br. Dent. J , vol.186 , pp. 286-296
    • Eley, B.M.1
  • 255
    • 14744280776 scopus 로고    scopus 로고
    • Homeopathy for menopausal symptoms in breast cancer survivors: A preliminary randomized controlled trial
    • Jacobs, J.; Herman, P.; Heron, K.; Olsen, S.; Vaughters, L. Homeopathy for menopausal symptoms in breast cancer survivors: A preliminary randomized controlled trial. J. Altern. Complement. Med. 2005, 11, 21-27
    • (2005) J. Altern. Complement. Med , vol.11 , pp. 21-27
    • Jacobs, J.1    Herman, P.2    Heron, K.3    Olsen, S.4    Vaughters, L.5
  • 256
    • 31144432815 scopus 로고    scopus 로고
    • Efficacy of homeopathic therapy in cancer treatment
    • Milazzo, S.; Russell, N.; Ernst, E. Efficacy of homeopathic therapy in cancer treatment. Eur. J. Cancer 2006, 42, 282-289
    • (2006) Eur. J. Cancer , vol.42 , pp. 282-289
    • Milazzo, S.1    Russell, N.2    Ernst, E.3
  • 257
    • 37849021933 scopus 로고    scopus 로고
    • Treating hot flushes in menopausal women with homeopathic treatment-Results of an observational study
    • Bordet, M.F.; Colas, A.; Marijnen, P.; Masson, J.L.; Trichard, M. Treating hot flushes in menopausal women with homeopathic treatment-Results of an observational study. Homeopathy 2008, 97, 10-15
    • (2008) Homeopathy , vol.97 , pp. 10-15
    • Bordet, M.F.1    Colas, A.2    Marijnen, P.3    Masson, J.L.4    Trichard, M.5
  • 258
    • 77958148715 scopus 로고    scopus 로고
    • Evaluating complementary therapies for canine osteoarthritis-Part II: A homeopathic combination preparation (zeel®)
    • Hielm-Björkman, A.; Tulamo, R.-M.; Salonen, H.; Raekallio, M. Evaluating complementary therapies for canine osteoarthritis-Part II: A homeopathic combination preparation (zeel®). Evid. Based Complement. Altern. Med. 2009, 6, 465-471
    • (2009) Evid. Based Complement. Altern. Med. , vol.6 , pp. 465-471
    • Hielm-Björkman, A.1    Tulamo, R.-M.2    Salonen, H.3    Raekallio, M.4
  • 259
    • 0001008621 scopus 로고    scopus 로고
    • Behandlung der gonarthrose mit zeel [r] comp.-ergebnisse einer randomisierten, kontrollierten klinischen pruefung im vergleich zu hyaluronsaeure
    • Nahler, G.; Metelmann, H.; Sperber, H. Behandlung der gonarthrose mit zeel [r] comp.-ergebnisse einer randomisierten, kontrollierten klinischen pruefung im vergleich zu hyaluronsaeure. Orthop. Pract. 1996, 32, 354-359.
    • (1996) Orthop. Pract , vol.32 , pp. 354-359
    • Nahler, G.1    Metelmann, H.2    Sperber, H.3
  • 260
    • 85052252667 scopus 로고    scopus 로고
    • (accessed on 16 August 2016)
    • Oral Treatment of Arthritis of the Knee with Zeel® Comp. Available online: http://www.homotoxicology.net/Documents/Brochures/Zeel.pdf (accessed on 16 August 2016).
  • 261
    • 33646520237 scopus 로고    scopus 로고
    • A modern homeopathic medication works as well as COX 2 inhibitors
    • Birnesser, H.; Klein, P.; Weiser, M. A modern homeopathic medication works as well as COX 2 inhibitors. Der Allg. 2003, 25, 261-264.
    • (2003) Der Allg , vol.25 , pp. 261-264
    • Birnesser, H.1    Klein, P.2    Weiser, M.3
  • 262
    • 0006667901 scopus 로고
    • Pre-excisional fixation of tissues in the treatment of cancer in rats
    • Mohs, F.; Guyer, M. Pre-excisional fixation of tissues in the treatment of cancer in rats. Cancer Res. 1941, 1, 49-51.
    • (1941) Cancer Res , vol.1 , pp. 49-51
    • Mohs, F.1    Guyer, M.2
  • 263
    • 23944439188 scopus 로고    scopus 로고
    • Accuracy of serial transverse cross-sections in detecting residual basal cell carcinoma at the surgical margins of an elliptical excision specimen
    • Kimyai-Asadi, A.; Goldberg, L.H.; Jih, M.H. Accuracy of serial transverse cross-sections in detecting residual basal cell carcinoma at the surgical margins of an elliptical excision specimen. J. Am. Acad. Dermatol. 2005, 53, 468-473
    • (2005) J. Am. Acad. Dermatol , vol.53 , pp. 468-473
    • Kimyai-Asadi, A.1    Goldberg, L.H.2    Jih, M.H.3
  • 264
    • 79952744345 scopus 로고    scopus 로고
    • History of mohs surgery
    • Trost, L.B.; Bailin, P.L. History of mohs surgery. Dermatol. Clin. 2011, 29, 135-139
    • (2011) Dermatol. Clin , vol.29 , pp. 135-139
    • Trost, L.B.1    Bailin, P.L.2
  • 265
    • 0000129480 scopus 로고
    • Chemosurgery: A microscopically controlled method of cancer excision
    • Mohs, F.E. Chemosurgery: A microscopically controlled method of cancer excision. Arch. Surg. 1941, 42, 279-295
    • (1941) Arch. Surg , vol.42 , pp. 279-295
    • Mohs, F.E.1
  • 266
    • 0015015637 scopus 로고
    • Chemosurgery and skin cancer
    • Mohs, F.E.; Caruso, R. Chemosurgery and skin cancer. AORN J. 1971, 13, 89-97
    • (1971) AORN J , vol.13 , pp. 89-97
    • Mohs, F.E.1    Caruso, R.2
  • 267
    • 0017809587 scopus 로고
    • Chemosurgery: Microscopically controlled surgery for skin cancer-Past, present and future
    • Mohs, F.E. Chemosurgery: Microscopically controlled surgery for skin cancer-Past, present and future. J. Dermatol. Surg. Oncol. 1978, 4, 41-54
    • (1978) J. Dermatol. Surg. Oncol , vol.4 , pp. 41-54
    • Mohs, F.E.1
  • 268
    • 0017274540 scopus 로고
    • Chemosurgery for skin cancer: Fixed tissue and fresh tissue techniques
    • Mohs, F.E. Chemosurgery for skin cancer: Fixed tissue and fresh tissue techniques. Arch. Dermatol. 1976, 112, 211-215
    • (1976) Arch. Dermatol , vol.112 , pp. 211-215
    • Mohs, F.E.1
  • 269
    • 84984856067 scopus 로고
    • Odyssey of an American cancer specialist of a hundred years ago
    • Farrow, R.T. Odyssey of an American cancer specialist of a hundred years ago. Bull. Hist. Med. 1949, 23, 236-262.
    • (1949) Bull. Hist. Med , vol.23 , pp. 236-262
    • Farrow, R.T.1
  • 271
    • 76549252781 scopus 로고
    • Bureau of investigation, comment on court opinion that internal cancer can be cured with medicine
    • Journal of the American Medical Association. Bureau of investigation, comment on court opinion that internal cancer can be cured with medicine. JAMA 1951, 145, 252-253.
    • (1951) JAMA , vol.145 , pp. 252-253
  • 273
    • 0006064226 scopus 로고
    • Long term follow-up of cancer patients using contreras, hoxsey and gerson therapies
    • Austin, S.; Baumgartner, E.; DeKadt, S. Long term follow-up of cancer patients using contreras, hoxsey and gerson therapies. J. Naturop. Med. 1995, 5, 74-76.
    • (1995) J. Naturop. Med. , vol.5 , pp. 74-76
    • Austin, S.1    Baumgartner, E.2    Dekadt, S.3
  • 275
    • 23944443058 scopus 로고    scopus 로고
    • Escharotic and other botanical agents for the treatment of skin cancer: A review
    • Jellinek, N.; Maloney, M.E. Escharotic and other botanical agents for the treatment of skin cancer: A review. J. Am. Acad. Dermatol. 2005, 53, 487-495
    • (2005) J. Am. Acad. Dermatol. , vol.53 , pp. 487-495
    • Jellinek, N.1    Maloney, M.E.2
  • 277
    • 84984789943 scopus 로고    scopus 로고
    • (accessed on 15 July 2016)
    • Earth Circle Creation. Available online: http://shop.earthcirclecreations.com/product_info.php?cPath=61&products_id=263 (accessed on 15 July 2016).
  • 278
    • 84901441560 scopus 로고    scopus 로고
    • Use of unlicensed black salve for cutaneous malignancy
    • Ong, N.C.; Sham, E.; Adams, B.M. Use of unlicensed black salve for cutaneous malignancy. Med. J. Aust. 2014, 200, 314
    • (2014) Med. J. Aust , vol.200
    • Ong, N.C.1    Sham, E.2    Adams, B.M.3
  • 279
    • 0036900719 scopus 로고    scopus 로고
    • Consequences of using escharotic agents as primary treatment for nonmelanoma skin cancer
    • McDaniel, S.; Goldman, G.D. Consequences of using escharotic agents as primary treatment for nonmelanoma skin cancer. Arch. Dermatol. 2002, 138, 1593-1596
    • (2002) Arch. Dermatol , vol.138 , pp. 1593-1596
    • McDaniel, S.1    Goldman, G.D.2
  • 280
    • 77958186200 scopus 로고    scopus 로고
    • An internet misadventure: Bloodroot salve toxicity
    • Cienki, J.J.; Zaret, L. An internet misadventure: Bloodroot salve toxicity. J. Altern. Complement. Med. 2010, 16, 1125-1127
    • (2010) J. Altern. Complement. Med , vol.16 , pp. 1125-1127
    • Cienki, J.J.1    Zaret, L.2
  • 281
    • 84976519711 scopus 로고    scopus 로고
    • Application of black salve to a thin melanoma that subsequently progressed to metastatic melanoma: A case study
    • Sivyer, G.W.; Rosendahl, C. Application of black salve to a thin melanoma that subsequently progressed to metastatic melanoma: A case study. Dermatol. Pract. Concept. 2014, 4, 77-80
    • (2014) Dermatol. Pract. Concept. , vol.4 , pp. 77-80
    • Sivyer, G.W.1    Rosendahl, C.2
  • 284
    • 54249155522 scopus 로고    scopus 로고
    • Network pharmacology: The next paradigm in drug discovery
    • Hopkins, A.L. Network pharmacology: The next paradigm in drug discovery. Nat. Chem. Biol. 2008, 4, 682-690
    • (2008) Nat. Chem. Biol , vol.4 , pp. 682-690
    • Hopkins, A.L.1
  • 285
    • 0034005776 scopus 로고    scopus 로고
    • Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells
    • Ahmad, N.; Gupta, S.; Husain, M.M.; Heiskanen, K.M.; Mukhtar, H. Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells. Clin. Cancer Res. 2000, 6, 1524-1528
    • (2000) Clin. Cancer Res , vol.6 , pp. 1524-1528
    • Ahmad, N.1    Gupta, S.2    Husain, M.M.3    Heiskanen, K.M.4    Mukhtar, H.5
  • 286
    • 84946201894 scopus 로고    scopus 로고
    • Combinations of alkaloids affecting different molecular targets with the saponin digitonin can synergistically enhance trypanocidal activity against Trypanosoma brucei
    • Krstin, S.; Peixoto, H.S.; Wink, M. Combinations of alkaloids affecting different molecular targets with the saponin digitonin can synergistically enhance trypanocidal activity against Trypanosoma brucei. Antimicrob. Agents Chemother. 2015, 59, 7011-7017
    • (2015) Antimicrob. Agents Chemother , vol.59 , pp. 7011-7017
    • Krstin, S.1    Peixoto, H.S.2    Wink, M.3
  • 287
    • 84876111608 scopus 로고    scopus 로고
    • Capillary electrophoretic study of the synergistic biological effects of alkaloids from Chelidonium majus l. In normal and cancer cells
    • Kulp, M.; Bragina, O. Capillary electrophoretic study of the synergistic biological effects of alkaloids from Chelidonium majus l. In normal and cancer cells. Anal. Bioanal. Chem. 2013, 405, 3391-3397
    • (2013) Anal. Bioanal. Chem. , vol.405 , pp. 3391-3397
    • Kulp, M.1    Bragina, O.2
  • 288
    • 0037446974 scopus 로고    scopus 로고
    • A genetic explanation of slaughter’s concept of field cancerization evidence and clinical implications
    • Braakhuis, B.J.; Tabor, M.P.; Kummer, J.A.; Leemans, C.R.; Brakenhoff, R.H. A genetic explanation of slaughter’s concept of field cancerization evidence and clinical implications. Cancer Res. 2003, 63, 1727-1730
    • (2003) Cancer Res , vol.63 , pp. 1727-1730
    • Braakhuis, B.J.1    Tabor, M.P.2    Kummer, J.A.3    Leemans, C.R.4    Brakenhoff, R.H.5
  • 289
    • 78149464296 scopus 로고    scopus 로고
    • Potentiation of tumour promotion by topical application of argemone oil/isolated sanguinarine alkaloid in a model of mouse skin carcinogenesis
    • Ansari, K.M.; Das, M. Potentiation of tumour promotion by topical application of argemone oil/isolated sanguinarine alkaloid in a model of mouse skin carcinogenesis. Chem. Biol. Interact. 2010, 188, 591-597
    • (2010) Chem. Biol. Interact , vol.188 , pp. 591-597
    • Ansari, K.M.1    Das, M.2
  • 290
    • 34447642659 scopus 로고    scopus 로고
    • Protective effect of sanguinarine on ultraviolet B-mediated damages in SKH-1 hairless mouse skin: Implications for prevention of skin cancer
    • Ahsan, H.; Reagan-Shaw, S.; Eggert, D.M.; Tan, T.C.; Afaq, F.; Mukhtar, H.; Ahmad, N. Protective effect of sanguinarine on ultraviolet B-mediated damages in SKH-1 hairless mouse skin: Implications for prevention of skin cancer. Photochem. Photobiol. 2007, 83, 986-993
    • (2007) Photochem. Photobiol. , vol.83 , pp. 986-993
    • Ahsan, H.1    Reagan-Shaw, S.2    Eggert, D.M.3    Tan, T.C.4    Afaq, F.5    Mukhtar, H.6    Ahmad, N.7
  • 291
    • 33644974099 scopus 로고    scopus 로고
    • Enhancement of UVB radiation-mediated apoptosis by sanguinarine in hacat human immortalized keratinocytes
    • Reagan-Shaw, S.; Breur, J.; Ahmad, N. Enhancement of UVB radiation-mediated apoptosis by sanguinarine in hacat human immortalized keratinocytes. Mol. Cancer Ther. 2006, 5, 418-429
    • (2006) Mol. Cancer Ther , vol.5 , pp. 418-429
    • Reagan-Shaw, S.1    Breur, J.2    Ahmad, N.3
  • 292
    • 0026614057 scopus 로고
    • Therapeutic landscapes: Medical issues in light of the new cultural geography
    • Gesler, W.M. Therapeutic landscapes: Medical issues in light of the new cultural geography. Soc. Sci. Med. 1992, 34, 735-746
    • (1992) Soc. Sci. Med , vol.34 , pp. 735-746
    • Gesler, W.M.1
  • 293
    • 84866491179 scopus 로고    scopus 로고
    • Prevalence of complementary and alternative medicine (CAM) use by the general population: A systematic review and update
    • Harris, P.; Cooper, K.; Relton, C.; Thomas, K. Prevalence of complementary and alternative medicine (CAM) use by the general population: A systematic review and update. Int. J. Clin. Pract. 2012, 66, 924-939
    • (2012) Int. J. Clin. Pract. , vol.66 , pp. 924-939
    • Harris, P.1    Cooper, K.2    Relton, C.3    Thomas, K.4
  • 294
    • 43949115541 scopus 로고    scopus 로고
    • Herbal medicine in the united states: Review of efficacy, safety, and regulation
    • Bent, S. Herbal medicine in the united states: Review of efficacy, safety, and regulation. J. Gen. Intern. Med. 2008, 23, 854-859
    • (2008) J. Gen. Intern. Med , vol.23 , pp. 854-859
    • Bent, S.1
  • 295
    • 0037137578 scopus 로고    scopus 로고
    • Botanical medicines-The need for new regulations
    • Board, S. Botanical medicines-The need for new regulations. N. Engl. J. Med. 2002, 347, 2073-2076.
    • (2002) N. Engl. J. Med , vol.347 , pp. 2073-2076
    • Board, S.1
  • 296
    • 84949657290 scopus 로고    scopus 로고
    • Combined DNA, toxicological and heavy metal analyses provides an auditing toolkit to improve pharmacovigilance of traditional Chinese medicine (TCM)
    • Coghlan, M.L.; Maker, G.; Crighton, E.; Haile, J.; Murray, D.C.; White, N.E.; Byard, R.W.; Bellgard, M.I.; Mullaney, I.; Trengove, R. Combined DNA, toxicological and heavy metal analyses provides an auditing toolkit to improve pharmacovigilance of traditional Chinese medicine (TCM). Sci. Rep. 2015, 5, 17475
    • (2015) Sci. Rep , vol.5
    • Coghlan, M.L.1    Maker, G.2    Crighton, E.3    Haile, J.4    Murray, D.C.5    White, N.E.6    Byard, R.W.7    Bellgard, M.I.8    Mullaney, I.9    Trengove, R.10


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