Inhibitory activity on binding of specific ligands to the human angiotensin II AT1 and endothelin 1 ETA receptors: Bioactive benzo[c]phenanthridine alkaloids from the root of Bocconia frutescens

Planta Medica

Volumn 68, Issue 9, 2002, Pages 770-775

  Caballero George, Catherina ^a   Vanderheyden, Patrick M L ^b   Apers, Sandra ^a   Den Heuvel, Hilde Van ^a   Solis, Pablo N ^c   Gupta, Mahabir P ^c   Claeys, Magda ^a   Pieters, Luc ^a   Vauquelin, Georges ^b   Vlietinck, Arnold J ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c UNIVERSIDAD DE PANAMÁ   (Panama)

Author keywords

Benzophenanthridine alkaloids; Bocconia frutescens; CHO cells; ETA receptor; hATI receptor; Papaveraceae; SK N MC cells

Indexed keywords

ALKALOID DERIVATIVE; ALLOCRYPTOPINE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; BENZO[C]PHENANTHRIDINE DERIVATIVE; BERBERINE; CANADINIUM; CANDESARTAN; CHELERYTHRINE; CHELIDONINE; CHELIRUBINE; COPRISINE; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ISOCORYLPALMINE; MACARPINE; PROTOBERBERINE DERIVATIVE; PROTOPINE; SANGUINARINE; SCOULERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOASSAY; BOCCONIA FRUTESCENS; CHO CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; DRUG ISOLATION; HUMAN; HUMAN CELL; HYPERTENSION; LIGAND BINDING; NEUROBLASTOMA CELL; NONHUMAN; PLANT ROOT; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; ANGIOTENSIN II; ANIMALS; BENZOPHENANTHRIDINES; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INHIBITORY CONCENTRATION 50; ISOQUINOLINES; LIGANDS; MOLECULAR STRUCTURE; PAPAVERACEAE; PEPTIDES, CYCLIC; PHENANTHRIDINES; PLANT EXTRACTS; PLANT ROOTS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ENDOTHELIN A; RECEPTORS, ANGIOTENSIN; RECEPTORS, ENDOTHELIN; TRITIUM; TUMOR CELLS, CULTURED;

ANIMALIA; BOCCONIA FRUTESCENS; CRICETINAE; CRICETULUS GRISEUS; PAPAVERACEAE;

EID: 18644363955     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-34406     Document Type: Article

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