Plant alkaloid chelerythrine induced aggregation of human telomere sequence-a unique mode of association between a small molecule and a quadruplex

Biochemistry

Volumn 54, Issue 4, 2015, Pages 974-986

  Ghosh, Saptaparni ^a   Jana, Jagannath ^b   Kar, Rajiv K ^b   Chatterjee, Subhrangsu ^b   Dasgupta, Dipak ^a  

^a SAHA INSTITUTE OF NUCLEAR PHYSICS   (India)

^b BOSE INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CALORIMETERS; CALORIMETRY; CELL CULTURE; CIRCULAR DICHROISM SPECTROSCOPY; DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; DISSOCIATION; DNA SEQUENCES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS; MOLECULES; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ABSORBANCE AND CIRCULAR DICHROISMS; CALORIMETRIC TECHNIQUES; DISSOCIATION CONSTANT; G-QUADRUPLEX STRUCTURE; HUMAN TELOMERE SEQUENCES; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DYNAMICS SIMULATIONS; QUADRUPLEX STRUCTURES;

BINDING ENERGY;

ANTINEOPLASTIC AGENT; CHELERYTHRINE; GUANINE QUADRUPLEX; TELOMERASE; ALKALOID; BENZOPHENANTHRIDINE DERIVATIVE; PROTEIN AGGREGATE; PROTEIN BINDING;

ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISSOCIATION CONSTANT; DNA SEQUENCE; DRUG DNA BINDING; ENTHALPY; ENTROPY; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTON NUCLEAR MAGNETIC RESONANCE; STOICHIOMETRY; CHEMISTRY; HELA CELL LINE; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; TELOMERE; X RAY CRYSTALLOGRAPHY;

ALKALOIDS; BASE SEQUENCE; BENZOPHENANTHRIDINES; CRYSTALLOGRAPHY, X-RAY; G-QUADRUPLEXES; HELA CELLS; HUMANS; PROTEIN AGGREGATES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TELOMERE;

EID: 84922254798     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi501117x     Document Type: Article

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