Sanguinarine-induced apoptosis in lung adenocarcinoma cells is dependent on reactive oxygen species production and endoplasmic reticulum stress

Oncology Reports

Volumn 34, Issue 2, 2015, Pages 913-919

  Gu, Shuang ^a,b   Yang, Xiao Chun ^a   Xiang, X I Yan ^a   Wu, Yao ^a   Zhang, Y U ^a   Yan, Xiao Y U ^a   Xue, Y A Nan ^a   Sun, Lian Kun ^a   Shao, Guo Guang ^a  

^a JILIN UNIVERSITY   (China)

^b Jilin Province   (China)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Lung adenocarcinoma; Reactive oxygen species; Sanguinarine

Indexed keywords

ACETYLCYSTEINE; ACTIVATING TRANSCRIPTION FACTOR 4; CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN HOMOLOGOUS PROTEIN; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; P PROTEIN KINASE R LIKE ER KINASE; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SANGUINARINE; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG; BENZOPHENANTHRIDINE DERIVATIVE; ISOQUINOLINE DERIVATIVE;

ADENOCARCINOMA CELL LINE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL FATE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; GENE FREQUENCY; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA CELL LINE; PRIORITY JOURNAL; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ADENOCARCINOMA; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; LUNG NEOPLASMS; METABOLISM; TUMOR CELL LINE;

ACETYLCYSTEINE; ADENOCARCINOMA; APOPTOSIS; BENZOPHENANTHRIDINES; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOQUINOLINES; LUNG NEOPLASMS; REACTIVE OXYGEN SPECIES;

EID: 84931390369     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.4054     Document Type: Article

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