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Volumn 24, Issue 3, 2010, Pages 697-706

Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells

Author keywords

Anti oxidant; Benzo(c)phenanthridine alkaloids; Chelilutine; Cytotoxicity; Oxidative stress; Sanguilutine

Indexed keywords

ALKALOID; ANTIOXIDANT; CAFFEINE CITRATE; CHELERYTHRINE; CHELILUTINE; CHLOROGENIC ACID; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; SANGUILUTINE; SANGUINARINE; TROLOX C; UNCLASSIFIED DRUG;

EID: 77649182612     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.01.012     Document Type: Article
Times cited : (45)

References (48)
  • 1
    • 0043026772 scopus 로고    scopus 로고
    • Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes
    • Adhami V.M., Aziz M.H., Mukhtar H., and Ahmad N. Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes. Clinical Cancer Research 9 (2003) 3176-3182
    • (2003) Clinical Cancer Research , vol.9 , pp. 3176-3182
    • Adhami, V.M.1    Aziz, M.H.2    Mukhtar, H.3    Ahmad, N.4
  • 2
    • 0034005776 scopus 로고    scopus 로고
    • Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells
    • Ahmad N., Gupta S., Husain M.M., Heiskanen K.M., and Mukhtar H. Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells. Clinical Cancer Research 6 (2000) 1524-1528
    • (2000) Clinical Cancer Research , vol.6 , pp. 1524-1528
    • Ahmad, N.1    Gupta, S.2    Husain, M.M.3    Heiskanen, K.M.4    Mukhtar, H.5
  • 3
    • 77649181062 scopus 로고    scopus 로고
    • Plant alkaloid sanguinarine prevents Ultraviolet B radiation-mediated damages in the skin of SKH1 hairless mouse
    • Ahsan H., Reagan-Shaw S., Eggert D., Afaq F., Mukhtar H., and Ahmad N. Plant alkaloid sanguinarine prevents Ultraviolet B radiation-mediated damages in the skin of SKH1 hairless mouse. Journal of Investigative Dermatology 126 Suppl. 1 (2006) 141
    • (2006) Journal of Investigative Dermatology , vol.126 , Issue.SUPPL. 1 , pp. 141
    • Ahsan, H.1    Reagan-Shaw, S.2    Eggert, D.3    Afaq, F.4    Mukhtar, H.5    Ahmad, N.6
  • 5
    • 33846626446 scopus 로고    scopus 로고
    • Induction of necrosis and apoptosis to KB cancer cells by sanguinarine associated with reactive oxygen species production and mitochondrial membrane depolarization
    • Chang M.C., Chan C.P., Wang Y.J., Lee P.H., Chen L.I., Tsai Y.L., Lin B.R., Wang Y.L., and Jeng J.H. Induction of necrosis and apoptosis to KB cancer cells by sanguinarine associated with reactive oxygen species production and mitochondrial membrane depolarization. Toxicology and Applied Pharmacology 218 (2007) 143-151
    • (2007) Toxicology and Applied Pharmacology , vol.218 , pp. 143-151
    • Chang, M.C.1    Chan, C.P.2    Wang, Y.J.3    Lee, P.H.4    Chen, L.I.5    Tsai, Y.L.6    Lin, B.R.7    Wang, Y.L.8    Jeng, J.H.9
  • 6
    • 0033961302 scopus 로고    scopus 로고
    • In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumour cell toxicity and growth delay in vivo
    • Chmura S.J., Dolan M.E., Cha A., Mauceri H.J., Kufe D.W., and Weichselbaum R.R. In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumour cell toxicity and growth delay in vivo. Clinical Cancer Research 6 (2000) 737-742
    • (2000) Clinical Cancer Research , vol.6 , pp. 737-742
    • Chmura, S.J.1    Dolan, M.E.2    Cha, A.3    Mauceri, H.J.4    Kufe, D.W.5    Weichselbaum, R.R.6
  • 7
    • 0037713603 scopus 로고    scopus 로고
    • Sanguinarine-induced apoptosis is associated with an early and severe cellular glutathione depletion
    • Debiton E., Madelmont J.C., Legault J., and Barthomeuf C. Sanguinarine-induced apoptosis is associated with an early and severe cellular glutathione depletion. Cancer Chemotherapy and Pharmacology 51 (2003) 474-482
    • (2003) Cancer Chemotherapy and Pharmacology , vol.51 , pp. 474-482
    • Debiton, E.1    Madelmont, J.C.2    Legault, J.3    Barthomeuf, C.4
  • 8
    • 0037090858 scopus 로고    scopus 로고
    • The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death
    • Ding Z.H., Tang S.C., Weerasinghe P., Yang X.L., Pater A., and Liepins A. The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death. Biochemical Pharmacology 63 (2002) 1415-1421
    • (2002) Biochemical Pharmacology , vol.63 , pp. 1415-1421
    • Ding, Z.H.1    Tang, S.C.2    Weerasinghe, P.3    Yang, X.L.4    Pater, A.5    Liepins, A.6
  • 9
    • 77957022972 scopus 로고    scopus 로고
    • Some aspects of the chemistry of quaternary benzo[c]phenanthridine alkaloids
    • Atta-ur-Rahman (Ed), Elsevier Science, Oxford
    • Dostal J., and Slavik J. Some aspects of the chemistry of quaternary benzo[c]phenanthridine alkaloids. In: Atta-ur-Rahman (Ed). Studies in Natural Products Chemistry vol. 27 (2002), Elsevier Science, Oxford 155-184
    • (2002) Studies in Natural Products Chemistry , vol.27 , pp. 155-184
    • Dostal, J.1    Slavik, J.2
  • 10
    • 25444461827 scopus 로고    scopus 로고
    • Ukrain - a new cancer cure? A systematic review of randomised clinical trials
    • Ernst E., and Schmidt K. Ukrain - a new cancer cure? A systematic review of randomised clinical trials. BMC Cancer 5 (2005) 69
    • (2005) BMC Cancer , vol.5 , pp. 69
    • Ernst, E.1    Schmidt, K.2
  • 11
    • 0032783532 scopus 로고    scopus 로고
    • Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2′,7′-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2′,7′-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123
    • Hempel S.L., Buettner G.R., O'Malley Y.Q., Wessels D.A., and Flaherty D.M. Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2′,7′-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2′,7′-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123. Free Radical Biology and Medicine 27 (1999) 146-159
    • (1999) Free Radical Biology and Medicine , vol.27 , pp. 146-159
    • Hempel, S.L.1    Buettner, G.R.2    O'Malley, Y.Q.3    Wessels, D.A.4    Flaherty, D.M.5
  • 12
    • 0029077137 scopus 로고
    • Synthesis of macarpine and its cytotoxicity - toward a synthetic route for 12-alkoxybenzo[c]phenanthridine alkaloids through aromatic nitrosation under basic condition
    • Ishikawa T., Saito T., and Ishii H. Synthesis of macarpine and its cytotoxicity - toward a synthetic route for 12-alkoxybenzo[c]phenanthridine alkaloids through aromatic nitrosation under basic condition. Tetrahedron 51 (1995) 8447-8458
    • (1995) Tetrahedron , vol.51 , pp. 8447-8458
    • Ishikawa, T.1    Saito, T.2    Ishii, H.3
  • 14
    • 40849146903 scopus 로고    scopus 로고
    • A decisive role of mitochondria in defining rate and intensity of apoptosis induction by different alkaloids
    • Kaminskyy V., Kulachkovskyy O., and Stoika R. A decisive role of mitochondria in defining rate and intensity of apoptosis induction by different alkaloids. Toxicology Letters 177 (2008) 168-181
    • (2008) Toxicology Letters , vol.177 , pp. 168-181
    • Kaminskyy, V.1    Kulachkovskyy, O.2    Stoika, R.3
  • 15
    • 33748308871 scopus 로고    scopus 로고
    • Correlation of the cytotoxic activity of four different alkaloids, from Chelidonium majus (greater celandine), with their DNA intercalating properties and ability to induce breaks in the DNA of NK/Ly murine lymphoma cells
    • Kaminskyy V.O., Lootsik M.D., and Stoika R.S. Correlation of the cytotoxic activity of four different alkaloids, from Chelidonium majus (greater celandine), with their DNA intercalating properties and ability to induce breaks in the DNA of NK/Ly murine lymphoma cells. Central European Journal of Biology 1 (2006) 2-15
    • (2006) Central European Journal of Biology , vol.1 , pp. 2-15
    • Kaminskyy, V.O.1    Lootsik, M.D.2    Stoika, R.S.3
  • 16
    • 33746310059 scopus 로고    scopus 로고
    • Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine
    • Kemeny-Beke A., Aradi J., Damjanovich J., Beck Z., Facsko A., Berta A., and Bodnar A. Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine. Cancer Letters 237 (2006) 67-75
    • (2006) Cancer Letters , vol.237 , pp. 67-75
    • Kemeny-Beke, A.1    Aradi, J.2    Damjanovich, J.3    Beck, Z.4    Facsko, A.5    Berta, A.6    Bodnar, A.7
  • 17
    • 45149130752 scopus 로고    scopus 로고
    • Sanguinarine-induced apoptosis: Generation of ROS, down-regulation of Bcl-2, c-FLIP, and synergy with TRAIL
    • Kim S., Lee T.J., Leem J., Choi K.S., Park J.W., and Kwon T.K. Sanguinarine-induced apoptosis: Generation of ROS, down-regulation of Bcl-2, c-FLIP, and synergy with TRAIL. Journal of Cellular Biochemistry 104 (2008) 895-907
    • (2008) Journal of Cellular Biochemistry , vol.104 , pp. 895-907
    • Kim, S.1    Lee, T.J.2    Leem, J.3    Choi, K.S.4    Park, J.W.5    Kwon, T.K.6
  • 19
    • 33749326967 scopus 로고    scopus 로고
    • The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine
    • Malikova J., Zdarilova A., Hlobilkova A., and Ulrichova J. The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine. Cell Biology and Toxicology 22 (2006) 439-453
    • (2006) Cell Biology and Toxicology , vol.22 , pp. 439-453
    • Malikova, J.1    Zdarilova, A.2    Hlobilkova, A.3    Ulrichova, J.4
  • 20
    • 48849113980 scopus 로고    scopus 로고
    • Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis
    • Matkar S.S., Wrischnik L.A., and Hellmann-Blumberg U. Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis. Archives of Biochemistry and Biophysics 477 (2008) 43-52
    • (2008) Archives of Biochemistry and Biophysics , vol.477 , pp. 43-52
    • Matkar, S.S.1    Wrischnik, L.A.2    Hellmann-Blumberg, U.3
  • 21
    • 39549088303 scopus 로고    scopus 로고
    • Sanguinarine causes DNA damage and p53-independent cell death in human colon cancer cell lines
    • Matkar S.S., Wrischnik L.A., and Hellmann-Blumberg U. Sanguinarine causes DNA damage and p53-independent cell death in human colon cancer cell lines. Chemico-Biological Interactions 172 (2008) 63-71
    • (2008) Chemico-Biological Interactions , vol.172 , pp. 63-71
    • Matkar, S.S.1    Wrischnik, L.A.2    Hellmann-Blumberg, U.3
  • 22
    • 0033059590 scopus 로고    scopus 로고
    • Structural considerations of NK109, an antitumour benzo[c]phenanthridine alkaloid
    • Nakanishi T., Suzuki M., Saimoto A., and Kabasawa T. Structural considerations of NK109, an antitumour benzo[c]phenanthridine alkaloid. Journal of Natural Products 62 (1999) 864-867
    • (1999) Journal of Natural Products , vol.62 , pp. 864-867
    • Nakanishi, T.1    Suzuki, M.2    Saimoto, A.3    Kabasawa, T.4
  • 23
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • Newman D.J., and Cragg G.M. Natural products as sources of new drugs over the last 25 years. Journal of Natural Products 70 (2007) 461-477
    • (2007) Journal of Natural Products , vol.70 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 24
    • 38549178993 scopus 로고    scopus 로고
    • Apoptogenic activity of two benzophenanthridine alkaloids from Chelidonium majus L. does not correlate with their DNA damaging effects
    • Philchenkov A., Kaminskyy V., Zavelevich M., and Stoika R. Apoptogenic activity of two benzophenanthridine alkaloids from Chelidonium majus L. does not correlate with their DNA damaging effects. Toxicology in Vitro 22 (2008) 287-295
    • (2008) Toxicology in Vitro , vol.22 , pp. 287-295
    • Philchenkov, A.1    Kaminskyy, V.2    Zavelevich, M.3    Stoika, R.4
  • 25
  • 26
    • 13444309267 scopus 로고    scopus 로고
    • Bioassay analysis using R
    • doi: http://www.bioassay.dk, 22p
    • Ritz, Ch., Streibig JC., 2005. Bioassay analysis using R. Journal of Statistical Software 12, 22p., doi: http://www.bioassay.dk.
    • (2005) Journal of Statistical Software , vol.12
    • Ritz, C.1    Streibig, J.C.2
  • 28
    • 0032879278 scopus 로고    scopus 로고
    • Statistical test for Hormesis and effective dosage in herbicide dose response
    • Schabenberger O., Tharp B.E., Kells J.J., and Penner D. Statistical test for Hormesis and effective dosage in herbicide dose response. Agronomy Journal 91 (1999) 713-721
    • (1999) Agronomy Journal , vol.91 , pp. 713-721
    • Schabenberger, O.1    Tharp, B.E.2    Kells, J.J.3    Penner, D.4
  • 29
    • 77957094472 scopus 로고
    • Benzophenanthridine Alkaloids
    • Brossi A. (Ed), Academic Press, Orlando
    • Simanek V. Benzophenanthridine Alkaloids. In: Brossi A. (Ed). The Alkaloids vol. 26 (1985), Academic Press, Orlando 185-240
    • (1985) The Alkaloids , vol.26 , pp. 185-240
    • Simanek, V.1
  • 30
    • 33646238998 scopus 로고    scopus 로고
    • Quaternary benzo(c)phenanthridine alkaloids - biological activities
    • Schneider M.P. (Ed), Kluwer Academic Publishers, Netherlands
    • Simanek V., Vespalec R., Sedo A., Ulrichova J., and Vicar J. Quaternary benzo(c)phenanthridine alkaloids - biological activities. In: Schneider M.P. (Ed). Chemical Probes in Biology (2003), Kluwer Academic Publishers, Netherlands 245-254
    • (2003) Chemical Probes in Biology , pp. 245-254
    • Simanek, V.1    Vespalec, R.2    Sedo, A.3    Ulrichova, J.4    Vicar, J.5
  • 31
    • 0034932996 scopus 로고    scopus 로고
    • Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells
    • Slaninova I., Taborska E., Bochorakova H., and Slanina J. Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells. Cell Biology and Toxicology 17 (2001) 51-63
    • (2001) Cell Biology and Toxicology , vol.17 , pp. 51-63
    • Slaninova, I.1    Taborska, E.2    Bochorakova, H.3    Slanina, J.4
  • 32
    • 33947259466 scopus 로고    scopus 로고
    • Screening of minor benzo(c)phenanthridine alkaloids for antiproliferative and apoptotic activities
    • Slaninova I., Slunska Z., Sinkora J., Vlkova M., and Taborska E. Screening of minor benzo(c)phenanthridine alkaloids for antiproliferative and apoptotic activities. Pharmaceutical Biology 45 (2007) 131-139
    • (2007) Pharmaceutical Biology , vol.45 , pp. 131-139
    • Slaninova, I.1    Slunska, Z.2    Sinkora, J.3    Vlkova, M.4    Taborska, E.5
  • 33
    • 34548312218 scopus 로고    scopus 로고
    • Quaternary benzo[c]phenanthridine alkaloids - novel cell permeant and red fluorescing DNA probes
    • Slaninova I., Slanina J., and Taborska E. Quaternary benzo[c]phenanthridine alkaloids - novel cell permeant and red fluorescing DNA probes. Cytometry Part A 71A (2007) 700-708
    • (2007) Cytometry Part A , vol.71 A , pp. 700-708
    • Slaninova, I.1    Slanina, J.2    Taborska, E.3
  • 34
    • 0000791234 scopus 로고
    • Alkaloide der mohngewächse (Papaveraceae) XVII. Über neue alkaloide aus Sanguinaria canadensis L
    • Slavik J., and Slavikova L. Alkaloide der mohngewächse (Papaveraceae) XVII. Über neue alkaloide aus Sanguinaria canadensis L. Collection of Czechoslovak Chemical Communications 25 (1960) 1667-1675
    • (1960) Collection of Czechoslovak Chemical Communications , vol.25 , pp. 1667-1675
    • Slavik, J.1    Slavikova, L.2
  • 36
    • 0035976358 scopus 로고    scopus 로고
    • Cytotoxicity of natural compounds in hepatocyte cell culture models - the case of quaternary benzo[c]phenanthridine alkaloids
    • Ulrichova J., Dvorak Z., Vicar J., Lata J., Smrzova J., Sedo A., and Simanek V. Cytotoxicity of natural compounds in hepatocyte cell culture models - the case of quaternary benzo[c]phenanthridine alkaloids. Toxicology Letters 125 (2001) 125-132
    • (2001) Toxicology Letters , vol.125 , pp. 125-132
    • Ulrichova, J.1    Dvorak, Z.2    Vicar, J.3    Lata, J.4    Smrzova, J.5    Sedo, A.6    Simanek, V.7
  • 37
    • 67349146742 scopus 로고    scopus 로고
    • Fluorescence properties of selected benzo[c]phenantridine alkaloids and studies of their interaction with CT DNA
    • Urbanova J., Lubal P., Slaninova I., Taborska E., and Taborsky P. Fluorescence properties of selected benzo[c]phenantridine alkaloids and studies of their interaction with CT DNA. Analytical and Bioanalytical Chemistry 394 (2009) 997-1002
    • (2009) Analytical and Bioanalytical Chemistry , vol.394 , pp. 997-1002
    • Urbanova, J.1    Lubal, P.2    Slaninova, I.3    Taborska, E.4    Taborsky, P.5
  • 38
    • 0000223347 scopus 로고
    • Biological activity of quaternary benzo[c]phenanthridine alkaloids - sanguinarine and chelerythrine
    • Vavreckova C., and Ulrichova J. Biological activity of quaternary benzo[c]phenanthridine alkaloids - sanguinarine and chelerythrine. Chemicke Listy 88 (1994) 238-248
    • (1994) Chemicke Listy , vol.88 , pp. 238-248
    • Vavreckova, C.1    Ulrichova, J.2
  • 39
    • 0347285302 scopus 로고    scopus 로고
    • Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism
    • Vrba J., Hrbac J., Ulrichova J., and Modriansky M. Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism. Chemico-Biological Interactions 147 (2004) 35-47
    • (2004) Chemico-Biological Interactions , vol.147 , pp. 35-47
    • Vrba, J.1    Hrbac, J.2    Ulrichova, J.3    Modriansky, M.4
  • 41
    • 0032820452 scopus 로고    scopus 로고
    • Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader
    • Wang H., and Joseph J.A. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radical Biology and Medicine 27 (1999) 612-616
    • (1999) Free Radical Biology and Medicine , vol.27 , pp. 612-616
    • Wang, H.1    Joseph, J.A.2
  • 42
    • 0034867935 scopus 로고    scopus 로고
    • Bax, Bcl-2, and NF-kappa B expression in sanguinarine induced bimodal cell death
    • Weerasinghe P., Hallock S., and Liepins A. Bax, Bcl-2, and NF-kappa B expression in sanguinarine induced bimodal cell death. Experimental and Molecular Pathology 71 (2001) 89-98
    • (2001) Experimental and Molecular Pathology , vol.71 , pp. 89-98
    • Weerasinghe, P.1    Hallock, S.2    Liepins, A.3
  • 43
    • 0035655509 scopus 로고    scopus 로고
    • Role of Bcl-2 family proteins and caspase-3 in sanguinarine-induced bimodal cell death
    • Weerasinghe P., Hallock S., Tang S.C., and Liepins A. Role of Bcl-2 family proteins and caspase-3 in sanguinarine-induced bimodal cell death. Cell Biology and Toxicology 17 (2001) 371-381
    • (2001) Cell Biology and Toxicology , vol.17 , pp. 371-381
    • Weerasinghe, P.1    Hallock, S.2    Tang, S.C.3    Liepins, A.4
  • 44
    • 0035210497 scopus 로고    scopus 로고
    • Sanguinarine induces bimodal cell death in K562 but not in high Bcl-2-expressing JM1 cells
    • Weerasinghe P., Hallock S., Tang S.C., and Liepins A. Sanguinarine induces bimodal cell death in K562 but not in high Bcl-2-expressing JM1 cells. Pathology Research and Practice 197 (2001) 717-726
    • (2001) Pathology Research and Practice , vol.197 , pp. 717-726
    • Weerasinghe, P.1    Hallock, S.2    Tang, S.C.3    Liepins, A.4
  • 46
    • 20444502200 scopus 로고    scopus 로고
    • Reactive oxygen species-mediated induction of apoptosis by a plant alkaloid 6-methoxydihydrosanguinarine in HepG2 cells
    • Yin H.Q., Kim Y.H., Moon C.K., and Lee B.H. Reactive oxygen species-mediated induction of apoptosis by a plant alkaloid 6-methoxydihydrosanguinarine in HepG2 cells. Biochemical Pharmacology 70 (2005) 242-248
    • (2005) Biochemical Pharmacology , vol.70 , pp. 242-248
    • Yin, H.Q.1    Kim, Y.H.2    Moon, C.K.3    Lee, B.H.4
  • 48
    • 33645522293 scopus 로고    scopus 로고
    • Quaternary isoquinoline alkaloids sanguinarine and chelerythrine. In vitro and in vivo effects
    • Zdarilova A., Malikova J., Dvorak Z., Ulrichova J., and Simanek V. Quaternary isoquinoline alkaloids sanguinarine and chelerythrine. In vitro and in vivo effects. Chemicke Listy 100 (2006) 30-41
    • (2006) Chemicke Listy , vol.100 , pp. 30-41
    • Zdarilova, A.1    Malikova, J.2    Dvorak, Z.3    Ulrichova, J.4    Simanek, V.5


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