Targeting DNA topoisomerase II in cancer chemotherapy

Nature Reviews Cancer

Volumn 9, Issue 5, 2009, Pages 338-350

  Nitiss, John L ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACLARUBICIN; AMONAFIDE; AMSACRINE; ANTHRACYCLINE; ATM PROTEIN; BIS(DIOXOPIPERAZINE) DERIVATIVE; BORTEZOMIB; CAMPTOTHECIN DERIVATIVE; DAUNORUBICIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; ELLIPTICINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; ETOPOSIDE; GYRASE INHIBITOR; MERBARONE; MITOXANTRONE; MONOCLONAL ANTIBODY; NOVOBIOCIN; PLATINUM DERIVATIVE; PROTEIN; QAP 1; RAZOXANE; SOBUZOXANE; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; VINCA ALKALOID;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CARDIOMYOPATHY; CARDIOTOXICITY; CATALYSIS; CHROMOSOME SEGREGATION; DNA ADDUCT; DNA DAMAGE; DNA PROTEIN COMPLEX; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; DNA TRANSCRIPTION; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME STRUCTURE; GENE MUTATION; GENOMICS; HEART PROTECTION; HODGKIN DISEASE; HUMAN; METASTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS; CATALYSIS; DNA; DNA REPAIR; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; HUMANS; TOPOISOMERASE II INHIBITORS;

EID: 64649090292     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc2607     Document Type: Review

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