-
1
-
-
0015383455
-
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
-
4561027
-
J.F.Kerr, A.H.Wyllie, A.R.Currie. Apoptosis:a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26:239-57; PMID:4561027; http://dx.doi.org/10.1038/bjc.1972.33
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
2
-
-
0024389675
-
The human blastocyst: cell number, death and allocation during late preimplantation development in vitro
-
2612378
-
K.Hardy, A.H.Handyside, R.M.Winston. The human blastocyst:cell number, death and allocation during late preimplantation development in vitro. Development 1989; 107:597-604; PMID:2612378
-
(1989)
Development
, vol.107
, pp. 597-604
-
-
Hardy, K.1
Handyside, A.H.2
Winston, R.M.3
-
3
-
-
84255210700
-
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
-
21760595
-
L.Galluzzi, I.Vitale, J.M.Abrams, E.S.Alnemri, E.H.Baehrecke, M.V.Blagosklonny, T.M.Dawson, V.L.Dawson, W.S.El-Deiry, S.Fulda, et al. Molecular definitions of cell death subroutines:recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 2012; 19:107-20; PMID:21760595; http://dx.doi.org/10.1038/cdd.2011.96
-
(2012)
Cell Death Differ
, vol.19
, pp. 107-120
-
-
Galluzzi, L.1
Vitale, I.2
Abrams, J.M.3
Alnemri, E.S.4
Baehrecke, E.H.5
Blagosklonny, M.V.6
Dawson, T.M.7
Dawson, V.L.8
El-Deiry, W.S.9
Fulda, S.10
-
4
-
-
84939986310
-
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
-
25236395
-
L.Galluzzi, J.M.Bravo-San Pedro, I.Vitale, S.A.Aaronson, J.M.Abrams, D.Adam, E.S.Alnemri, L.Altucci, D.Andrews, M.Annicchiarico-Petruzzelli, et al. Essential versus accessory aspects of cell death:recommendations of the NCCD 2015. Cell Death Differ 2015; 22:58-73; PMID:25236395; http://dx.doi.org/10.1038/cdd.2014.137
-
(2015)
Cell Death Differ
, vol.22
, pp. 58-73
-
-
Galluzzi, L.1
Bravo-San Pedro, J.M.2
Vitale, I.3
Aaronson, S.A.4
Abrams, J.M.5
Adam, D.6
Alnemri, E.S.7
Altucci, L.8
Andrews, D.9
Annicchiarico-Petruzzelli, M.10
-
5
-
-
0000031083
-
Programmed Cell Death -II. Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths
-
R.A.Lockshin, C.M.Williams. Programmed Cell Death -II. Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths. J Ins Physiol 1964; 10:643-9; http://dx.doi.org/10.1016/0022-1910(64)90034-4
-
(1964)
J Ins Physiol
, vol.10
, pp. 643-649
-
-
Lockshin, R.A.1
Williams, C.M.2
-
6
-
-
84874263775
-
Necroptosis: the release of damage-associated molecular patterns and its physiological relevance
-
23438821
-
A.Kaczmarek, P.Vandenabeele, D.V.Krysko. Necroptosis:the release of damage-associated molecular patterns and its physiological relevance. Immunity 2013; 38:209-23; PMID:23438821; http://dx.doi.org/10.1016/j.immuni.2013.02.003
-
(2013)
Immunity
, vol.38
, pp. 209-223
-
-
Kaczmarek, A.1
Vandenabeele, P.2
Krysko, D.V.3
-
7
-
-
84907210946
-
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
-
25132550
-
M.Dannappel, K.Vlantis, S.Kumari, A.Polykratis, C.Kim, L.Wachsmuth, C.Eftychi, J.Lin, T.Corona, N.Hermance, et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 2014; 513:90-4; PMID:25132550; http://dx.doi.org/10.1038/nature13608
-
(2014)
Nature
, vol.513
, pp. 90-94
-
-
Dannappel, M.1
Vlantis, K.2
Kumari, S.3
Polykratis, A.4
Kim, C.5
Wachsmuth, L.6
Eftychi, C.7
Lin, J.8
Corona, T.9
Hermance, N.10
-
8
-
-
67649884532
-
CD95, BIM and T cell homeostasis
-
19543226
-
P.Bouillet, L.A.O'Reilly. CD95, BIM and T cell homeostasis. Nat Rev Immunol 2009; 9:514-9; PMID:19543226; http://dx.doi.org/10.1038/nri2570
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 514-519
-
-
Bouillet, P.1
O'Reilly, L.A.2
-
9
-
-
33747884339
-
DNA damage-induced cell death by apoptosis
-
16899408
-
W.P.Roos, B.Kaina. DNA damage-induced cell death by apoptosis. Trends Mol Med 2006; 12:440-50; PMID:16899408; http://dx.doi.org/10.1016/j.molmed.2006.07.007
-
(2006)
Trends Mol Med
, vol.12
, pp. 440-450
-
-
Roos, W.P.1
Kaina, B.2
-
10
-
-
67650928134
-
Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila
-
19521510
-
C.V.Nogueira, T.Lindsten, A.M.Jamieson, C.L.Case, S.Shin, C.B.Thompson, C.R.Roy. Rapid pathogen-induced apoptosis:a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. PLoS pathogens 2009; 5:e1000478; PMID:19521510; http://dx.doi.org/10.1371/journal.ppat.1000478
-
(2009)
PLoS pathogens
, vol.5
, pp. e1000478
-
-
Nogueira, C.V.1
Lindsten, T.2
Jamieson, A.M.3
Case, C.L.4
Shin, S.5
Thompson, C.B.6
Roy, C.R.7
-
11
-
-
0030447483
-
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
-
8943045
-
H.B.Shu, M.Takeuchi, D.V.Goeddel. The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. Proc Natl Acad Sci U S A 1996; 93:13973-8; PMID:8943045; http://dx.doi.org/10.1073/pnas.93.24.13973
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13973-13978
-
-
Shu, H.B.1
Takeuchi, M.2
Goeddel, D.V.3
-
12
-
-
0041853690
-
Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
-
12887920
-
O.Micheau, J.Tschopp. Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes. Cell 2003; 114:181-90; PMID:12887920; http://dx.doi.org/10.1016/S0092-8674(03)00521-X
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
13
-
-
0034743199
-
NF-kappaB signals induce the expression of c-FLIP
-
11463813
-
O.Micheau, S.Lens, O.Gaide, K.Alevizopoulos, J.Tschopp. NF-kappaB signals induce the expression of c-FLIP. Mol Cell Biol 2001; 21:5299-305; PMID:11463813; http://dx.doi.org/10.1128/MCB.21.16.5299-5305.2001
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
14
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
11101870
-
N.Holler, R.Zaru, O.Micheau, M.Thome, A.Attinger, S.Valitutti, J.L.Bodmer, P.Schneider, B.Seed, J.Tschopp. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 2000; 1:489-95; PMID:11101870; http://dx.doi.org/10.1038/82732
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
Bodmer, J.L.7
Schneider, P.8
Seed, B.9
Tschopp, J.10
-
15
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
8521815
-
F.C.Kischkel, S.Hellbardt, I.Behrmann, M.Germer, M.Pawlita, P.H.Krammer, M.E.Peter. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J 1995; 14:5579-88; PMID:8521815
-
(1995)
EMBO J
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.H.6
Peter, M.E.7
-
16
-
-
84856764253
-
Regulation of CD95/Fas signaling at the DISC
-
22075988
-
I.N.Lavrik, P.H.Krammer. Regulation of CD95/Fas signaling at the DISC. Cell Death Differ 2012; 19:36-41; PMID:22075988; http://dx.doi.org/10.1038/cdd.2011.155
-
(2012)
Cell Death Differ
, vol.19
, pp. 36-41
-
-
Lavrik, I.N.1
Krammer, P.H.2
-
17
-
-
84863486901
-
A novel role for RIP1 kinase in mediating TNFalpha production
-
22695613
-
D.E.Christofferson, Y.Li, J.Hitomi, W.Zhou, C.Upperman, H.Zhu, S.A.Gerber, S.Gygi, J.Yuan. A novel role for RIP1 kinase in mediating TNFalpha production. Cell Death Dis 2012; 3:e320; PMID:22695613; http://dx.doi.org/10.1038/cddis.2012.64
-
(2012)
Cell Death Dis
, vol.3
, pp. e320
-
-
Christofferson, D.E.1
Li, Y.2
Hitomi, J.3
Zhou, W.4
Upperman, C.5
Zhu, H.6
Gerber, S.A.7
Gygi, S.8
Yuan, J.9
-
18
-
-
0037815277
-
Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis
-
12721308
-
N.Harper, M.Hughes, M.MacFarlane, G.M.Cohen. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis. J Biol Chem 2003; 278:25534-41; PMID:12721308; http://dx.doi.org/10.1074/jbc.M303399200
-
(2003)
J Biol Chem
, vol.278
, pp. 25534-25541
-
-
Harper, N.1
Hughes, M.2
MacFarlane, M.3
Cohen, G.M.4
-
19
-
-
44949240664
-
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
18570872
-
M.J.Bertrand, S.Milutinovic, K.M.Dickson, W.C.Ho, A.Boudreault, J.Durkin, J.W.Gillard, J.B.Jaquith, S.J.Morris, P.A.Barker. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 2008; 30:689-700; PMID:18570872; http://dx.doi.org/10.1016/j.molcel.2008.05.014
-
(2008)
Mol Cell
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
Gillard, J.W.7
Jaquith, J.B.8
Morris, S.J.9
Barker, P.A.10
-
20
-
-
54049155149
-
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation
-
18621737
-
E.Varfolomeev, T.Goncharov, A.V.Fedorova, J.N.Dynek, K.Zobel, K.Deshayes, W.J.Fairbrother, D.Vucic. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation. J Biol Chem 2008; 283:24295-9; PMID:18621737; http://dx.doi.org/10.1074/jbc.C800128200
-
(2008)
J Biol Chem
, vol.283
, pp. 24295-24299
-
-
Varfolomeev, E.1
Goncharov, T.2
Fedorova, A.V.3
Dynek, J.N.4
Zobel, K.5
Deshayes, K.6
Fairbrother, W.J.7
Vucic, D.8
-
21
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
-
14532286
-
F.K.Chan, J.Shisler, J.G.Bixby, M.Felices, L.Zheng, M.Appel, J.Orenstein, B.Moss, M.J.Lenardo. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J Biol Chem 2003; 278:51613-21; PMID:14532286; http://dx.doi.org/10.1074/jbc.M305633200
-
(2003)
J Biol Chem
, vol.278
, pp. 51613-51621
-
-
Chan, F.K.1
Shisler, J.2
Bixby, J.G.3
Felices, M.4
Zheng, L.5
Appel, M.6
Orenstein, J.7
Moss, B.8
Lenardo, M.J.9
-
22
-
-
84943198837
-
TRAF2 is a biologically important necroptosis suppressor
-
25882049
-
S.L.Petersen, T.T.Chen, D.A.Lawrence, S.A.Marsters, F.Gonzalvez, A.Ashkenazi. TRAF2 is a biologically important necroptosis suppressor. Cell Death Differ 2015; 22(11):1846-57; PMID:25882049; http://dx.doi.org/10.1038/cdd.2015.35
-
(2015)
Cell Death Differ
, vol.22
, Issue.11
, pp. 1846-1857
-
-
Petersen, S.L.1
Chen, T.T.2
Lawrence, D.A.3
Marsters, S.A.4
Gonzalvez, F.5
Ashkenazi, A.6
-
23
-
-
84876886863
-
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO
-
23453807
-
A.K.Muller-Rischart, A.Pilsl, P.Beaudette, M.Patra, K.Hadian, M.Funke, R.Peis, A.Deinlein, C.Schweimer, P.H.Kuhn, et al. The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. Mol Cell 2013; 49:908-21; PMID:23453807; http://dx.doi.org/10.1016/j.molcel.2013.01.036
-
(2013)
Mol Cell
, vol.49
, pp. 908-921
-
-
Muller-Rischart, A.K.1
Pilsl, A.2
Beaudette, P.3
Patra, M.4
Hadian, K.5
Funke, M.6
Peis, R.7
Deinlein, A.8
Schweimer, C.9
Kuhn, P.H.10
-
24
-
-
84867062977
-
A20 inhibits LUBAC-mediated NF-kappaB activation by binding linear polyubiquitin chains via its zinc finger 7
-
23032186
-
K.Verhelst, I.Carpentier, M.Kreike, L.Meloni, L.Verstrepen, T.Kensche, I.Dikic, R.Beyaert. A20 inhibits LUBAC-mediated NF-kappaB activation by binding linear polyubiquitin chains via its zinc finger 7. EMBO J 2012; 31:3845-55; PMID:23032186; http://dx.doi.org/10.1038/emboj.2012.240
-
(2012)
EMBO J
, vol.31
, pp. 3845-3855
-
-
Verhelst, K.1
Carpentier, I.2
Kreike, M.3
Meloni, L.4
Verstrepen, L.5
Kensche, T.6
Dikic, I.7
Beyaert, R.8
-
25
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
21368763
-
A.Oberst, C.P.Dillon, R.Weinlich, L.L.McCormick, P.Fitzgerald, C.Pop, R.Hakem, G.S.Salvesen, D.R.Green. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 2011; 471:363-7; PMID:21368763; http://dx.doi.org/10.1038/nature09852
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
26
-
-
78751487532
-
FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
-
21235526
-
C.Pop, A.Oberst, M.Drag, B.J.Van Raam, S.J.Riedl, D.R.Green, G.S.Salvesen. FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity. Biochem J 2011; 433:447-57; PMID:21235526; http://dx.doi.org/10.1042/BJ20101738
-
(2011)
Biochem J
, vol.433
, pp. 447-457
-
-
Pop, C.1
Oberst, A.2
Drag, M.3
Van Raam, B.J.4
Riedl, S.J.5
Green, D.R.6
Salvesen, G.S.7
-
27
-
-
27644505459
-
Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1
-
16251271
-
H.E.Kim, F.Du, M.Fang, X.Wang. Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. Proc Natl Acad Sci U S A 2005; 102:17545-50; PMID:16251271; http://dx.doi.org/10.1073/pnas.0507900102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 17545-17550
-
-
Kim, H.E.1
Du, F.2
Fang, M.3
Wang, X.4
-
28
-
-
84927644965
-
The BH3-only protein Bad is dispensable for TNF-mediated cell death
-
25611386
-
E.Ottina, M.Sochalska, R.Sgonc, A.Villunger. The BH3-only protein Bad is dispensable for TNF-mediated cell death. Cell Death Dis 2015; 6:e1611; PMID:25611386; http://dx.doi.org/10.1038/cddis.2014.575
-
(2015)
Cell Death Dis
, vol.6
, pp. e1611
-
-
Ottina, E.1
Sochalska, M.2
Sgonc, R.3
Villunger, A.4
-
29
-
-
84855714255
-
BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation
-
21738214
-
L.Cabon, P.Galan-Malo, A.Bouharrour, L.Delavallee, M.N.Brunelle-Navas, H.K.Lorenzo, A.Gross, S.A.Susin. BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation. Cell Death Differ 2012; 19:245-56; PMID:21738214; http://dx.doi.org/10.1038/cdd.2011.91
-
(2012)
Cell Death Differ
, vol.19
, pp. 245-256
-
-
Cabon, L.1
Galan-Malo, P.2
Bouharrour, A.3
Delavallee, L.4
Brunelle-Navas, M.N.5
Lorenzo, H.K.6
Gross, A.7
Susin, S.A.8
-
30
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
10929711
-
C.Du, M.Fang, Y.Li, L.Li, X.Wang. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102:33-42; PMID:10929711; http://dx.doi.org/10.1016/S0092-8674(00)00008-8
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
31
-
-
36148954336
-
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
-
18022363
-
J.E.Vince, W.W.Wong, N.Khan, R.Feltham, D.Chau, A.U.Ahmed, C.A.Benetatos, S.K.Chunduru, S.M.Condon, M.McKinlay, et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007; 131:682-93; PMID:18022363; http://dx.doi.org/10.1016/j.cell.2007.10.037
-
(2007)
Cell
, vol.131
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
Benetatos, C.A.7
Chunduru, S.K.8
Condon, S.M.9
McKinlay, M.10
-
32
-
-
36048999753
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
-
18022362
-
E.Varfolomeev, J.W.Blankenship, S.M.Wayson, A.V.Fedorova, N.Kayagaki, P.Garg, K.Zobel, J.N.Dynek, L.O.Elliott, H.J.Wallweber, et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007; 131:669-81; PMID:18022362; http://dx.doi.org/10.1016/j.cell.2007.10.030
-
(2007)
Cell
, vol.131
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
Zobel, K.7
Dynek, J.N.8
Elliott, L.O.9
Wallweber, H.J.10
-
33
-
-
84907222764
-
A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation
-
25107908
-
M.L.Wurstle, M.Rehm. A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation. J Biol Chem 2014; 289:26277-89; PMID:25107908; http://dx.doi.org/10.1074/jbc.M114.590034
-
(2014)
J Biol Chem
, vol.289
, pp. 26277-26289
-
-
Wurstle, M.L.1
Rehm, M.2
-
34
-
-
84867490138
-
Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML
-
23063124
-
T.T.Vo, J.Ryan, R.Carrasco, D.Neuberg, D.J.Rossi, R.M.Stone, D.J.Deangelo, M.G.Frattini, A.Letai. Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML. Cell 2012; 151:344-55; PMID:23063124; http://dx.doi.org/10.1016/j.cell.2012.08.038
-
(2012)
Cell
, vol.151
, pp. 344-355
-
-
Vo, T.T.1
Ryan, J.2
Carrasco, R.3
Neuberg, D.4
Rossi, D.J.5
Stone, R.M.6
Deangelo, D.J.7
Frattini, M.G.8
Letai, A.9
-
35
-
-
33749178260
-
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response
-
16950166
-
N.Festjens, T.Vanden Berghe, P.Vandenabeele. Necrosis, a well-orchestrated form of cell demise:signalling cascades, important mediators and concomitant immune response. Biochimica et biophysica acta 2006; 1757:1371-87; PMID:16950166; http://dx.doi.org/10.1016/j.bbabio.2006.06.014
-
(2006)
Biochimica et biophysica acta
, vol.1757
, pp. 1371-1387
-
-
Festjens, N.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
36
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
16408008
-
A.Degterev, Z.Huang, M.Boyce, Y.Li, P.Jagtap, N.Mizushima, G.D.Cuny, T.J.Mitchison, M.A.Moskowitz, J.Yuan. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005; 1:112-9; PMID:16408008; http://dx.doi.org/10.1038/nchembio711
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
Cuny, G.D.7
Mitchison, T.J.8
Moskowitz, M.A.9
Yuan, J.10
-
37
-
-
0030698810
-
The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death
-
9380409
-
T.Hirsch, P.Marchetti, S.A.Susin, B.Dallaporta, N.Zamzami, I.Marzo, M.Geuskens, G.Kroemer. The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene 1997; 15:1573-81; PMID:9380409; http://dx.doi.org/10.1038/sj.onc.1201324
-
(1997)
Oncogene
, vol.15
, pp. 1573-1581
-
-
Hirsch, T.1
Marchetti, P.2
Susin, S.A.3
Dallaporta, B.4
Zamzami, N.5
Marzo, I.6
Geuskens, M.7
Kroemer, G.8
-
38
-
-
0033679111
-
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation
-
10843390
-
P.J.Sansonetti, A.Phalipon, J.Arondel, K.Thirumalai, S.Banerjee, S.Akira, K.Takeda, A.Zychlinsky. Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation. Immunity 2000; 12:581-90; PMID:10843390; http://dx.doi.org/10.1016/S1074-7613(00)80209-5
-
(2000)
Immunity
, vol.12
, pp. 581-590
-
-
Sansonetti, P.J.1
Phalipon, A.2
Arondel, J.3
Thirumalai, K.4
Banerjee, S.5
Akira, S.6
Takeda, K.7
Zychlinsky, A.8
-
39
-
-
84892739389
-
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
-
24356306
-
G.Doitsh, N.L.Galloway, X.Geng, Z.Yang, K.M.Monroe, O.Zepeda, P.W.Hunt, H.Hatano, S.Sowinski, I.Munoz-Arias, et al. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature 2014; 505:509-14; PMID:24356306; http://dx.doi.org/10.1038/nature12940
-
(2014)
Nature
, vol.505
, pp. 509-514
-
-
Doitsh, G.1
Galloway, N.L.2
Geng, X.3
Yang, Z.4
Monroe, K.M.5
Zepeda, O.6
Hunt, P.W.7
Hatano, H.8
Sowinski, S.9
Munoz-Arias, I.10
-
40
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
15190255
-
S.Mariathasan, K.Newton, D.M.Monack, D.Vucic, D.M.French, W.P.Lee, M.Roose-Girma, S.Erickson, V.M.Dixit. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 2004; 430:213-8; PMID:15190255; http://dx.doi.org/10.1038/nature02664
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
41
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
12191486
-
F.Martinon, K.Burns, J.Tschopp. The inflammasome:a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 2002; 10:417-26; PMID:12191486; http://dx.doi.org/10.1016/S1097-2765(02)00599-3
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
42
-
-
84942892037
-
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
-
26375003
-
J.Shi, Y.Zhao, K.Wang, X.Shi, Y.Wang, H.Huang, Y.Zhuang, T.Cai, F.Wang, F.Shao. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 2015; 526:660-5; PMID:26375003; http://dx.doi.org/10.1038/nature15514
-
(2015)
Nature
, vol.526
, pp. 660-665
-
-
Shi, J.1
Zhao, Y.2
Wang, K.3
Shi, X.4
Wang, Y.5
Huang, H.6
Zhuang, Y.7
Cai, T.8
Wang, F.9
Shao, F.10
-
43
-
-
84942856523
-
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
-
26375259
-
N.Kayagaki, I.B.Stowe, B.L.Lee, K.O'Rourke, K.Anderson, S.Warming, T.Cuellar, B.Haley, M.Roose-Girma, Q.T.Phung, et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 2015; 526:666-71; PMID:26375259; http://dx.doi.org/10.1038/nature15541
-
(2015)
Nature
, vol.526
, pp. 666-671
-
-
Kayagaki, N.1
Stowe, I.B.2
Lee, B.L.3
O'Rourke, K.4
Anderson, K.5
Warming, S.6
Cuellar, T.7
Haley, B.8
Roose-Girma, M.9
Phung, Q.T.10
-
44
-
-
62449133719
-
Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium
-
19051310
-
N.Saeki, T.Usui, K.Aoyagi, D.H.Kim, M.Sato, T.Mabuchi, K.Yanagihara, K.Ogawa, H.Sakamoto, T.Yoshida, et al. Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium. Genes Chromosomes Cancer 2009; 48:261-71; PMID:19051310; http://dx.doi.org/10.1002/gcc.20636
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 261-271
-
-
Saeki, N.1
Usui, T.2
Aoyagi, K.3
Kim, D.H.4
Sato, M.5
Mabuchi, T.6
Yanagihara, K.7
Ogawa, K.8
Sakamoto, H.9
Yoshida, T.10
-
45
-
-
85027944163
-
Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells
-
25124554
-
V.Derangere, A.Chevriaux, F.Courtaut, M.Bruchard, H.Berger, F.Chalmin, S.Z.Causse, E.Limagne, F.Vegran, S.Ladoire, et al. Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells. Cell Death Differ 2014; 21:1914-24; PMID:25124554; http://dx.doi.org/10.1038/cdd.2014.117
-
(2014)
Cell Death Differ
, vol.21
, pp. 1914-1924
-
-
Derangere, V.1
Chevriaux, A.2
Courtaut, F.3
Bruchard, M.4
Berger, H.5
Chalmin, F.6
Causse, S.Z.7
Limagne, E.8
Vegran, F.9
Ladoire, S.10
-
46
-
-
84896764574
-
Spontaneous regression of a conjunctival malignant melanoma
-
24295209
-
C.V.Miller, I.S.Cook, R.Jayaramachandran, A.G.Tyers. Spontaneous regression of a conjunctival malignant melanoma. Orbit 2014; 33:139-41; PMID:24295209; http://dx.doi.org/10.3109/01676830.2013.851708
-
(2014)
Orbit
, vol.33
, pp. 139-141
-
-
Miller, C.V.1
Cook, I.S.2
Jayaramachandran, R.3
Tyers, A.G.4
-
47
-
-
84861541814
-
Ferroptosis: an iron-dependent form of nonapoptotic cell death
-
22632970
-
S.J.Dixon, K.M.Lemberg, M.R.Lamprecht, R.Skouta, E.M.Zaitsev, C.E.Gleason, D.N.Patel, A.J.Bauer, A.M.Cantley, W.S.Yang, et al. Ferroptosis:an iron-dependent form of nonapoptotic cell death. Cell 2012; 149:1060-72; PMID:22632970; http://dx.doi.org/10.1016/j.cell.2012.03.042
-
(2012)
Cell
, vol.149
, pp. 1060-1072
-
-
Dixon, S.J.1
Lemberg, K.M.2
Lamprecht, M.R.3
Skouta, R.4
Zaitsev, E.M.5
Gleason, C.E.6
Patel, D.N.7
Bauer, A.J.8
Cantley, A.M.9
Yang, W.S.10
-
48
-
-
84957429081
-
Ferroptosis: process and function
-
26794443
-
Y.Xie, W.Hou, X.Song, Y.Yu, J.Huang, X.Sun, R.Kang, D.Tang. Ferroptosis:process and function. Cell Death Differ 2016; 23:369-79; PMID:26794443; http://dx.doi.org/10.1038/cdd.2015.158
-
(2016)
Cell Death Differ
, vol.23
, pp. 369-379
-
-
Xie, Y.1
Hou, W.2
Song, X.3
Yu, Y.4
Huang, J.5
Sun, X.6
Kang, R.7
Tang, D.8
-
49
-
-
34250372956
-
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
-
17568748
-
N.Yagoda, M.von Rechenberg, E.Zaganjor, A.J.Bauer, W.S.Yang, D.J.Fridman, A.J.Wolpaw, I.Smukste, J.M.Peltier, J.J.Boniface, et al. RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature 2007; 447:864-8; PMID:17568748; http://dx.doi.org/10.1038/nature05859
-
(2007)
Nature
, vol.447
, pp. 864-868
-
-
Yagoda, N.1
von Rechenberg, M.2
Zaganjor, E.3
Bauer, A.J.4
Yang, W.S.5
Fridman, D.J.6
Wolpaw, A.J.7
Smukste, I.8
Peltier, J.M.9
Boniface, J.J.10
-
50
-
-
84975132567
-
An essential role for functional lysosomes in ferroptosis of cancer cells
-
26759376
-
S.Torii, R.Shintoku, C.Kubota, M.Yaegashi, R.Torii, M.Sasaki, T.Suzuki, M.Mori, Y.Yoshimoto, T.Takeuchi, et al. An essential role for functional lysosomes in ferroptosis of cancer cells. Biochem J 2016; 473:769-77; PMID:26759376; http://dx.doi.org/10.1042/BJ20150658
-
(2016)
Biochem J
, vol.473
, pp. 769-777
-
-
Torii, S.1
Shintoku, R.2
Kubota, C.3
Yaegashi, M.4
Torii, R.5
Sasaki, M.6
Suzuki, T.7
Mori, M.8
Yoshimoto, Y.9
Takeuchi, T.10
-
51
-
-
84890922670
-
The role of iron and reactive oxygen species in cell death
-
24346035
-
S.J.Dixon, B.R.Stockwell. The role of iron and reactive oxygen species in cell death. Nat Chem Biol 2014; 10:9-17; PMID:24346035; http://dx.doi.org/10.1038/nchembio.1416
-
(2014)
Nat Chem Biol
, vol.10
, pp. 9-17
-
-
Dixon, S.J.1
Stockwell, B.R.2
-
52
-
-
84957431913
-
Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells
-
26097885
-
N.Eling, L.Reuter, J.Hazin, A.Hamacher-Brady, N.R.Brady. Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells. Oncoscience 2015; 2:517-32; PMID:26097885; http://dx.doi.org/10.18632/oncoscience.160
-
(2015)
Oncoscience
, vol.2
, pp. 517-532
-
-
Eling, N.1
Reuter, L.2
Hazin, J.3
Hamacher-Brady, A.4
Brady, N.R.5
-
53
-
-
27144556223
-
Targeted treatment of cancer with artemisinin and artemisinin-tagged iron-carrying compounds
-
16185154
-
H.Lai, T.Sasaki, N.P.Singh. Targeted treatment of cancer with artemisinin and artemisinin-tagged iron-carrying compounds. Expert Opin Ther Targets 2005; 9:995-1007; PMID:16185154; http://dx.doi.org/10.1517/14728222.9.5.995
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 995-1007
-
-
Lai, H.1
Sasaki, T.2
Singh, N.P.3
-
54
-
-
84941550824
-
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
-
26407947
-
E.Ooko, M.E.Saeed, O.Kadioglu, S.Sarvi, M.Colak, K.Elmasaoudi, R.Janah, H.J.Greten, T.Efferth. Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells. Phytomedicine 2015; 22:1045-54; PMID:26407947; http://dx.doi.org/10.1016/j.phymed.2015.08.002
-
(2015)
Phytomedicine
, vol.22
, pp. 1045-1054
-
-
Ooko, E.1
Saeed, M.E.2
Kadioglu, O.3
Sarvi, S.4
Colak, M.5
Elmasaoudi, K.6
Janah, R.7
Greten, H.J.8
Efferth, T.9
-
55
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
19524513
-
Y.S.Cho, S.Challa, D.Moquin, R.Genga, T.D.Ray, M.Guildford, F.K.Chan. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009; 137:1112-23; PMID:19524513; http://dx.doi.org/10.1016/j.cell.2009.05.037
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.7
-
56
-
-
78650718758
-
Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
-
21098270
-
G.Trichonas, Y.Murakami, A.Thanos, Y.Morizane, M.Kayama, C.M.Debouck, T.Hisatomi, J.W.Miller, D.G.Vavvas. Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci U S A 2010; 107:21695-700; PMID:21098270; http://dx.doi.org/10.1073/pnas.1009179107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21695-21700
-
-
Trichonas, G.1
Murakami, Y.2
Thanos, A.3
Morizane, Y.4
Kayama, M.5
Debouck, C.M.6
Hisatomi, T.7
Miller, J.W.8
Vavvas, D.G.9
-
57
-
-
84884308522
-
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
-
24012422
-
J.M.Murphy, P.E.Czabotar, J.M.Hildebrand, I.S.Lucet, J.G.Zhang, S.Alvarez-Diaz, R.Lewis, N.Lalaoui, D.Metcalf, A.I.Webb, et al. The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity 2013; 39:443-53; PMID:24012422; http://dx.doi.org/10.1016/j.immuni.2013.06.018
-
(2013)
Immunity
, vol.39
, pp. 443-453
-
-
Murphy, J.M.1
Czabotar, P.E.2
Hildebrand, J.M.3
Lucet, I.S.4
Zhang, J.G.5
Alvarez-Diaz, S.6
Lewis, R.7
Lalaoui, N.8
Metcalf, D.9
Webb, A.I.10
-
58
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
1103152
-
E.A.Carswell, L.J.Old, R.L.Kassel, S.Green, N.Fiore, B.Williamson. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci U S A 1975; 72:3666-70; PMID:1103152; http://dx.doi.org/10.1073/pnas.72.9.3666
-
(1975)
Proc Natl Acad Sci U S A
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
59
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
19498109
-
D.W.Zhang, J.Shao, J.Lin, N.Zhang, B.J.Lu, S.C.Lin, M.Q.Dong, J.Han. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009; 325:332-6; PMID:19498109; http://dx.doi.org/10.1126/science.1172308
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
Dong, M.Q.7
Han, J.8
-
60
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
19524512
-
S.He, L.Wang, L.Miao, T.Wang, F.Du, L.Zhao, X.Wang. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009; 137:1100-11; PMID:19524512; http://dx.doi.org/10.1016/j.cell.2009.05.021
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
Wang, X.7
-
61
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
19109899
-
J.Hitomi, D.E.Christofferson, A.Ng, J.Yao, A.Degterev, R.J.Xavier, J.Yuan. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008; 135:1311-23; PMID:19109899; http://dx.doi.org/10.1016/j.cell.2008.10.044
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
Yuan, J.7
-
62
-
-
84864240409
-
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
-
22817896
-
J.Li, T.McQuade, A.B.Siemer, J.Napetschnig, K.Moriwaki, Y.S.Hsiao, E.Damko, D.Moquin, T.Walz, A.McDermott, et al. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell 2012; 150:339-50; PMID:22817896; http://dx.doi.org/10.1016/j.cell.2012.06.019
-
(2012)
Cell
, vol.150
, pp. 339-350
-
-
Li, J.1
McQuade, T.2
Siemer, A.B.3
Napetschnig, J.4
Moriwaki, K.5
Hsiao, Y.S.6
Damko, E.7
Moquin, D.8
Walz, T.9
McDermott, A.10
-
63
-
-
79960922705
-
cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
21737330
-
M.Feoktistova, P.Geserick, B.Kellert, D.P.Dimitrova, C.Langlais, M.Hupe, K.Cain, M.MacFarlane, G.Hacker, M.Leverkus. cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell 2011; 43:449-63; PMID:21737330; http://dx.doi.org/10.1016/j.molcel.2011.06.011
-
(2011)
Mol Cell
, vol.43
, pp. 449-463
-
-
Feoktistova, M.1
Geserick, P.2
Kellert, B.3
Dimitrova, D.P.4
Langlais, C.5
Hupe, M.6
Cain, K.7
MacFarlane, M.8
Hacker, G.9
Leverkus, M.10
-
64
-
-
77952236200
-
Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features
-
20010783
-
T.Vanden Berghe, N.Vanlangenakker, E.Parthoens, W.Deckers, M.Devos, N.Festjens, C.J.Guerin, U.T.Brunk, W.Declercq, P.Vandenabeele. Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features. Cell Death Differ 2010; 17:922-30; PMID:20010783; http://dx.doi.org/10.1038/cdd.2009.184
-
(2010)
Cell Death Differ
, vol.17
, pp. 922-930
-
-
Vanden Berghe, T.1
Vanlangenakker, N.2
Parthoens, E.3
Deckers, W.4
Devos, M.5
Festjens, N.6
Guerin, C.J.7
Brunk, U.T.8
Declercq, W.9
Vandenabeele, P.10
-
65
-
-
84891343566
-
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
-
24316671
-
Z.Cai, S.Jitkaew, J.Zhao, H.C.Chiang, S.Choksi, J.Liu, Y.Ward, L.G.Wu, Z.G.Liu. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 2014; 16:55-65; PMID:24316671; http://dx.doi.org/10.1038/ncb2883
-
(2014)
Nat Cell Biol
, vol.16
, pp. 55-65
-
-
Cai, Z.1
Jitkaew, S.2
Zhao, J.3
Chiang, H.C.4
Choksi, S.5
Liu, J.6
Ward, Y.7
Wu, L.G.8
Liu, Z.G.9
-
66
-
-
84882430393
-
Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases
-
23898178
-
R.J.Thapa, S.Nogusa, P.Chen, J.L.Maki, A.Lerro, M.Andrake, G.F.Rall, A.Degterev, S.Balachandran. Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases. Proc Natl Acad Sci U S A 2013; 110:E3109-18; PMID:23898178; http://dx.doi.org/10.1073/pnas.1301218110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. E3109-E3118
-
-
Thapa, R.J.1
Nogusa, S.2
Chen, P.3
Maki, J.L.4
Lerro, A.5
Andrake, M.6
Rall, G.F.7
Degterev, A.8
Balachandran, S.9
-
67
-
-
84898024383
-
Death induced by CD95 or CD95 ligand elimination
-
24656822
-
A.Hadji, P.Ceppi, A.E.Murmann, S.Brockway, A.Pattanayak, B.Bhinder, A.Hau, S.De Chant, V.Parimi, P.Kolesza, et al. Death induced by CD95 or CD95 ligand elimination. Cell Rep 2014; 7:208-22; PMID:24656822; http://dx.doi.org/10.1016/j.celrep.2014.02.035
-
(2014)
Cell Rep
, vol.7
, pp. 208-222
-
-
Hadji, A.1
Ceppi, P.2
Murmann, A.E.3
Brockway, S.4
Pattanayak, A.5
Bhinder, B.6
Hau, A.7
De Chant, S.8
Parimi, V.9
Kolesza, P.10
-
68
-
-
84905662023
-
Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages
-
25049377
-
S.McComb, E.Cessford, N.A.Alturki, J.Joseph, B.Shutinoski, J.B.Startek, A.M.Gamero, K.L.Mossman, S.Sad. Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages. Proc Natl Acad Sci U S A 2014; 111:E3206-13; PMID:25049377; http://dx.doi.org/10.1073/pnas.1407068111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E3206-E3213
-
-
McComb, S.1
Cessford, E.2
Alturki, N.A.3
Joseph, J.4
Shutinoski, B.5
Startek, J.B.6
Gamero, A.M.7
Mossman, K.L.8
Sad, S.9
-
69
-
-
84927671957
-
Programmed necrosis in the cross talk of cell death and inflammation
-
25493335
-
F.K.Chan, N.F.Luz, K.Moriwaki. Programmed necrosis in the cross talk of cell death and inflammation. Ann Rev Immunol 2015; 33:79-106; PMID:25493335; http://dx.doi.org/10.1146/annurev-immunol-032414-112248
-
(2015)
Ann Rev Immunol
, vol.33
, pp. 79-106
-
-
Chan, F.K.1
Luz, N.F.2
Moriwaki, K.3
-
70
-
-
84906535354
-
A long-awaited merger of the pathways mediating host defence and programmed cell death
-
25145756
-
J.M.Blander. A long-awaited merger of the pathways mediating host defence and programmed cell death. Nat Rev Immunol 2014; 14:601-18; PMID:25145756; http://dx.doi.org/10.1038/nri3720
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 601-618
-
-
Blander, J.M.1
-
71
-
-
84859424337
-
IAPs limit activation of RIP kinases by TNF receptor 1 during development
-
22327219
-
M.Moulin, H.Anderton, A.K.Voss, T.Thomas, W.W.Wong, A.Bankovacki, R.Feltham, D.Chau, W.D.Cook, J.Silke, et al. IAPs limit activation of RIP kinases by TNF receptor 1 during development. EMBO J 2012; 31:1679-91; PMID:22327219; http://dx.doi.org/10.1038/emboj.2012.18
-
(2012)
EMBO J
, vol.31
, pp. 1679-1691
-
-
Moulin, M.1
Anderton, H.2
Voss, A.K.3
Thomas, T.4
Wong, W.W.5
Bankovacki, A.6
Feltham, R.7
Chau, D.8
Cook, W.D.9
Silke, J.10
-
72
-
-
84255162797
-
RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome
-
22195746
-
L.Duprez, N.Takahashi, F.Van Hauwermeiren, B.Vandendriessche, V.Goossens, T.Vanden Berghe, W.Declercq, C.Libert, A.Cauwels, P.Vandenabeele. RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome. Immunity 2011; 35:908-18; PMID:22195746; http://dx.doi.org/10.1016/j.immuni.2011.09.020
-
(2011)
Immunity
, vol.35
, pp. 908-918
-
-
Duprez, L.1
Takahashi, N.2
Van Hauwermeiren, F.3
Vandendriessche, B.4
Goossens, V.5
Vanden Berghe, T.6
Declercq, W.7
Libert, C.8
Cauwels, A.9
Vandenabeele, P.10
-
73
-
-
33744951304
-
Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation
-
16543241
-
H.Li, M.Kobayashi, M.Blonska, Y.You, X.Lin. Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation. J Biol Chem 2006; 281:13636-43; PMID:16543241; http://dx.doi.org/10.1074/jbc.M600620200
-
(2006)
J Biol Chem
, vol.281
, pp. 13636-13643
-
-
Li, H.1
Kobayashi, M.2
Blonska, M.3
You, Y.4
Lin, X.5
-
74
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
20005846
-
T.L.Haas, C.H.Emmerich, B.Gerlach, A.C.Schmukle, S.M.Cordier, E.Rieser, R.Feltham, J.Vince, U.Warnken, T.Wenger, et al. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol Cell 2009; 36:831-44; PMID:20005846; http://dx.doi.org/10.1016/j.molcel.2009.10.013
-
(2009)
Mol Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
Feltham, R.7
Vince, J.8
Warnken, U.9
Wenger, T.10
-
75
-
-
84929875491
-
Regulation of tumour necrosis factor signalling: live or let die
-
26008591
-
D.Brenner, H.Blaser, T.W.Mak. Regulation of tumour necrosis factor signalling:live or let die. Nat Rev Immunol 2015; 15:362-74; PMID:26008591; http://dx.doi.org/10.1038/nri3834
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 362-374
-
-
Brenner, D.1
Blaser, H.2
Mak, T.W.3
-
76
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
21455173
-
B.Gerlach, S.M.Cordier, A.C.Schmukle, C.H.Emmerich, E.Rieser, T.L.Haas, A.I.Webb, J.A.Rickard, H.Anderton, W.W.Wong, et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 2011; 471:591-6; PMID:21455173; http://dx.doi.org/10.1038/nature09816
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
Emmerich, C.H.4
Rieser, E.5
Haas, T.L.6
Webb, A.I.7
Rickard, J.A.8
Anderton, H.9
Wong, W.W.10
-
77
-
-
83155192804
-
TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members
-
22089168
-
N.Vanlangenakker, M.J.Bertrand, P.Bogaert, P.Vandenabeele, T.Vanden Berghe. TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members. Cell Death Dis 2011; 2:e230; PMID:22089168; http://dx.doi.org/10.1038/cddis.2011.111
-
(2011)
Cell Death Dis
, vol.2
, pp. e230
-
-
Vanlangenakker, N.1
Bertrand, M.J.2
Bogaert, P.3
Vandenabeele, P.4
Vanden Berghe, T.5
-
78
-
-
84861712290
-
Survival function of the FADD-CASPASE-8-cFLIP(L) complex
-
22675671
-
C.P.Dillon, A.Oberst, R.Weinlich, L.J.Janke, T.B.Kang, T.Ben-Moshe, T.W.Mak, D.Wallach, D.R.Green. Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep 2012; 1:401-7; PMID:22675671; http://dx.doi.org/10.1016/j.celrep.2012.03.010
-
(2012)
Cell Rep
, vol.1
, pp. 401-407
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
Janke, L.J.4
Kang, T.B.5
Ben-Moshe, T.6
Mak, T.W.7
Wallach, D.8
Green, D.R.9
-
79
-
-
34548437549
-
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
-
17644308
-
S.Feng, Y.Yang, Y.Mei, L.Ma, D.E.Zhu, N.Hoti, M.Castanares, M.Wu. Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell Signal 2007; 19:2056-67; PMID:17644308; http://dx.doi.org/10.1016/j.cellsig.2007.05.016
-
(2007)
Cell Signal
, vol.19
, pp. 2056-2067
-
-
Feng, S.1
Yang, Y.2
Mei, Y.3
Ma, L.4
Zhu, D.E.5
Hoti, N.6
Castanares, M.7
Wu, M.8
-
80
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
22037414
-
M.A.O'Donnell, E.Perez-Jimenez, A.Oberst, A.Ng, R.Massoumi, R.Xavier, D.R.Green, A.T.Ting. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 2011; 13:1437-42; PMID:22037414; http://dx.doi.org/10.1038/ncb2362
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
Green, D.R.7
Ting, A.T.8
-
81
-
-
84959241995
-
CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3
-
26900751
-
J.Seo, E.W.Lee, H.Sung, D.Seong, Y.Dondelinger, J.Shin, M.Jeong, H.K.Lee, J.H.Kim, S.Y.Han, et al. CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3. Nat Cell Biol 2016; 18:291-302; PMID:26900751; http://dx.doi.org/10.1038/ncb3314
-
(2016)
Nat Cell Biol
, vol.18
, pp. 291-302
-
-
Seo, J.1
Lee, E.W.2
Sung, H.3
Seong, D.4
Dondelinger, Y.5
Shin, J.6
Jeong, M.7
Lee, H.K.8
Kim, J.H.9
Han, S.Y.10
-
82
-
-
84870570760
-
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
-
23190609
-
N.Takahashi, L.Duprez, S.Grootjans, A.Cauwels, W.Nerinckx, J.B.DuHadaway, V.Goossens, R.Roelandt, F.Van Hauwermeiren, C.Libert, et al. Necrostatin-1 analogues:critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis 2012; 3:e437; PMID:23190609; http://dx.doi.org/10.1038/cddis.2012.176
-
(2012)
Cell Death Dis
, vol.3
, pp. e437
-
-
Takahashi, N.1
Duprez, L.2
Grootjans, S.3
Cauwels, A.4
Nerinckx, W.5
DuHadaway, J.B.6
Goossens, V.7
Roelandt, R.8
Van Hauwermeiren, F.9
Libert, C.10
-
83
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
18408713
-
A.Degterev, J.Hitomi, M.Germscheid, I.L.Ch'en, O.Korkina, X.Teng, D.Abbott, G.D.Cuny, C.Yuan, G.Wagner, et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 2008; 4:313-21; PMID:18408713; http://dx.doi.org/10.1038/nchembio.83
-
(2008)
Nat Chem Biol
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
-
84
-
-
43049152912
-
TNF-alpha induces two distinct caspase-8 activation pathways
-
18485876
-
L.Wang, F.Du, X.Wang. TNF-alpha induces two distinct caspase-8 activation pathways. Cell 2008; 133:693-703; PMID:18485876; http://dx.doi.org/10.1016/j.cell.2008.03.036
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
85
-
-
84881184694
-
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
-
23835476
-
J.Wu, Z.Huang, J.Ren, Z.Zhang, P.He, Y.Li, J.Ma, W.Chen, Y.Zhang, X.Zhou, et al. Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res 2013; 23:994-1006; PMID:23835476; http://dx.doi.org/10.1038/cr.2013.91
-
(2013)
Cell Res
, vol.23
, pp. 994-1006
-
-
Wu, J.1
Huang, Z.2
Ren, J.3
Zhang, Z.4
He, P.5
Li, Y.6
Ma, J.7
Chen, W.8
Zhang, Y.9
Zhou, X.10
-
86
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
22265413
-
L.Sun, H.Wang, Z.Wang, S.He, S.Chen, D.Liao, L.Wang, J.Yan, W.Liu, X.Lei, et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 2012; 148:213-27; PMID:22265413; http://dx.doi.org/10.1016/j.cell.2011.11.031
-
(2012)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
Wang, H.2
Wang, Z.3
He, S.4
Chen, S.5
Liao, D.6
Wang, L.7
Yan, J.8
Liu, W.9
Lei, X.10
-
87
-
-
84901280344
-
MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates
-
24813885
-
Y.Dondelinger, W.Declercq, S.Montessuit, R.Roelandt, A.Goncalves, I.Bruggeman, P.Hulpiau, K.Weber, C.A.Sehon, R.W.Marquis, et al. MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates. Cell Rep 2014; 7:971-81; PMID:24813885; http://dx.doi.org/10.1016/j.celrep.2014.04.026
-
(2014)
Cell Rep
, vol.7
, pp. 971-981
-
-
Dondelinger, Y.1
Declercq, W.2
Montessuit, S.3
Roelandt, R.4
Goncalves, A.5
Bruggeman, I.6
Hulpiau, P.7
Weber, K.8
Sehon, C.A.9
Marquis, R.W.10
-
88
-
-
84898027331
-
Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3
-
24703947
-
H.Wang, L.Sun, L.Su, J.Rizo, L.Liu, L.F.Wang, F.S.Wang, X.Wang. Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3. Mol Cell 2014; 54:133-46; PMID:24703947; http://dx.doi.org/10.1016/j.molcel.2014.03.003
-
(2014)
Mol Cell
, vol.54
, pp. 133-146
-
-
Wang, H.1
Sun, L.2
Su, L.3
Rizo, J.4
Liu, L.5
Wang, L.F.6
Wang, F.S.7
Wang, X.8
-
89
-
-
84891739370
-
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death
-
24366341
-
X.Chen, W.Li, J.Ren, D.Huang, W.T.He, Y.Song, C.Yang, W.Li, X.Zheng, P.Chen, et al. Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death. Cell Res 2014; 24:105-21; PMID:24366341; http://dx.doi.org/10.1038/cr.2013.171
-
(2014)
Cell Res
, vol.24
, pp. 105-121
-
-
Chen, X.1
Li, W.2
Ren, J.3
Huang, D.4
He, W.T.5
Song, Y.6
Yang, C.7
Li, W.8
Zheng, X.9
Chen, P.10
-
90
-
-
84901257054
-
Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
-
24434512
-
Q.Remijsen, V.Goossens, S.Grootjans, C.Van den Haute, N.Vanlangenakker, Y.Dondelinger, R.Roelandt, I.Bruggeman, A.Goncalves, M.J.Bertrand, et al. Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis. Cell Death Dis 2014; 5:e1004; PMID:24434512; http://dx.doi.org/10.1038/cddis.2013.531
-
(2014)
Cell Death Dis
, vol.5
, pp. e1004
-
-
Remijsen, Q.1
Goossens, V.2
Grootjans, S.3
Van den Haute, C.4
Vanlangenakker, N.5
Dondelinger, Y.6
Roelandt, R.7
Bruggeman, I.8
Goncalves, A.9
Bertrand, M.J.10
-
91
-
-
84888438277
-
Widespread mitochondrial depletion via mitophagy does not compromise necroptosis
-
24268776
-
S.W.Tait, A.Oberst, G.Quarato, S.Milasta, M.Haller, R.Wang, M.Karvela, G.Ichim, N.Yatim, M.L.Albert, et al. Widespread mitochondrial depletion via mitophagy does not compromise necroptosis. Cell Rep 2013; 5:878-85; PMID:24268776; http://dx.doi.org/10.1016/j.celrep.2013.10.034
-
(2013)
Cell Rep
, vol.5
, pp. 878-885
-
-
Tait, S.W.1
Oberst, A.2
Quarato, G.3
Milasta, S.4
Haller, M.5
Wang, R.6
Karvela, M.7
Ichim, G.8
Yatim, N.9
Albert, M.L.10
-
92
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
22265414
-
Z.Wang, H.Jiang, S.Chen, F.Du, X.Wang. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 2012; 148:228-43; PMID:22265414; http://dx.doi.org/10.1016/j.cell.2011.11.030
-
(2012)
Cell
, vol.148
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
93
-
-
84953251956
-
The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages
-
K.Moriwaki, N.Farias Luz, S.Balaji, M.J.De Rosa, C.L.O'Donnell, P.J.Gough, J.Bertin, R.M.Welsh, F.K.Chan. The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. J Immunol 2016; 196:407-15; PMID:2682950; http://dx.doi.org/10.4049/jimmunol.1501662
-
(2016)
J Immunol
, vol.196
, pp. 407-415
-
-
Moriwaki, K.1
Farias Luz, N.2
Balaji, S.3
De Rosa, M.J.4
O'Donnell, C.L.5
Gough, P.J.6
Bertin, J.7
Welsh, R.M.8
Chan, F.K.9
-
94
-
-
84883411678
-
Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
-
23991283
-
J.Karch, J.Q.Kwong, A.R.Burr, M.A.Sargent, J.W.Elrod, P.M.Peixoto, S.Martinez-Caballero, H.Osinska, E.H.Cheng, J.Robbins, et al. Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice. eLife 2013; 2:e00772; PMID:23991283; http://dx.doi.org/10.7554/eLife.00772
-
(2013)
eLife
, vol.2
, pp. e00772
-
-
Karch, J.1
Kwong, J.Q.2
Burr, A.R.3
Sargent, M.A.4
Elrod, J.W.5
Peixoto, P.M.6
Martinez-Caballero, S.7
Osinska, H.8
Cheng, E.H.9
Robbins, J.10
-
95
-
-
80052583012
-
Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis
-
21746883
-
K.M.Irrinki, K.Mallilankaraman, R.J.Thapa, H.C.Chandramoorthy, F.J.Smith, N.R.Jog, R.K.Gandhirajan, S.G.Kelsen, S.R.Houser, M.J.May, et al. Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis. Mol Cell Biol 2011; 31:3745-58; PMID:21746883; http://dx.doi.org/10.1128/MCB.05303-11
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3745-3758
-
-
Irrinki, K.M.1
Mallilankaraman, K.2
Thapa, R.J.3
Chandramoorthy, H.C.4
Smith, F.J.5
Jog, N.R.6
Gandhirajan, R.K.7
Kelsen, S.G.8
Houser, S.R.9
May, M.J.10
-
96
-
-
84955476379
-
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
-
26463424
-
O.Canli, Y.B.Alankus, S.Grootjans, N.Vegi, L.Hultner, P.S.Hoppe, T.Schroeder, P.Vandenabeele, G.W.Bornkamm, F.R.Greten. Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors. Blood 2016; 127:139-48; PMID:26463424; http://dx.doi.org/10.1182/blood-2015-06-654194
-
(2016)
Blood
, vol.127
, pp. 139-148
-
-
Canli, O.1
Alankus, Y.B.2
Grootjans, S.3
Vegi, N.4
Hultner, L.5
Hoppe, P.S.6
Schroeder, T.7
Vandenabeele, P.8
Bornkamm, G.W.9
Greten, F.R.10
-
97
-
-
84947869935
-
Reactive oxygen species regulate Smac mimetic/TNFalpha-induced necroptotic signaling and cell death
-
34(47):5796-806;
-
B.Schenk, S.Fulda. Reactive oxygen species regulate Smac mimetic/TNFalpha-induced necroptotic signaling and cell death. Oncogene 2015 34(47):5796-806; http:dx.doi.org/10.1038/onc.2015.35
-
(2015)
Oncogene
-
-
Schenk, B.1
Fulda, S.2
-
98
-
-
84861195802
-
Necroptosis: an emerging form of programmed cell death
-
21962882
-
W.Wu, P.Liu, J.Li. Necroptosis:an emerging form of programmed cell death. Crit Rev Oncol Hematol 2012; 82:249-58; PMID:21962882; http://dx.doi.org/10.1016/j.critrevonc.2011.08.004
-
(2012)
Crit Rev Oncol Hematol
, vol.82
, pp. 249-258
-
-
Wu, W.1
Liu, P.2
Li, J.3
-
99
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
20203610
-
Q.Zhang, M.Raoof, Y.Chen, Y.Sumi, T.Sursal, W.Junger, K.Brohi, K.Itagaki, C.J.Hauser. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 2010; 464:104-7; PMID:20203610; http://dx.doi.org/10.1038/nature08780
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
Sumi, Y.4
Sursal, T.5
Junger, W.6
Brohi, K.7
Itagaki, K.8
Hauser, C.J.9
-
100
-
-
84875511757
-
Tumor necrosis factor-alpha blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation
-
23477736
-
M.Sade-Feldman, J.Kanterman, E.Ish-Shalom, M.Elnekave, E.Horwitz, M.Baniyash. Tumor necrosis factor-alpha blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation. Immunity 2013; 38:541-54; PMID:23477736; http://dx.doi.org/10.1016/j.immuni.2013.02.007
-
(2013)
Immunity
, vol.38
, pp. 541-554
-
-
Sade-Feldman, M.1
Kanterman, J.2
Ish-Shalom, E.3
Elnekave, M.4
Horwitz, E.5
Baniyash, M.6
-
101
-
-
84938989183
-
Melatonin attenuates carbon tetrachloride-induced liver fibrosis via inhibition of necroptosis
-
H.S.Choi, J.W.Kang, S.M.Lee. Melatonin attenuates carbon tetrachloride-induced liver fibrosis via inhibition of necroptosis. Translat Res 2015; 166(3):292-303; PMID:25936762; http://dx.doi.org/10.1016/j.trsl.2015.04.002
-
(2015)
Translat Res
-
-
Choi, H.S.1
Kang, J.W.2
Lee, S.M.3
-
102
-
-
0037180757
-
Inflammation and cancer
-
12490959
-
L.M.Coussens, Z.Werb. Inflammation and cancer. Nature 2002; 420:860-7; PMID:12490959; http://dx.doi.org/10.1038/nature01322
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
103
-
-
84880869807
-
The complexity of NF-kappaB signaling in inflammation and cancer
-
23915189
-
B.Hoesel, J.A.Schmid. The complexity of NF-kappaB signaling in inflammation and cancer. Mol Cancer 2013; 12:86; PMID:23915189; http://dx.doi.org/10.1186/1476-4598-12-86
-
(2013)
Mol Cancer
, vol.12
, pp. 86
-
-
Hoesel, B.1
Schmid, J.A.2
-
105
-
-
34250748014
-
Shikonin circumvents cancer drug resistance by induction of a necroptotic death
-
17513612
-
W.Han, L.Li, S.Qiu, Q.Lu, Q.Pan, Y.Gu, J.Luo, X.Hu. Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther 2007; 6:1641-9; PMID:17513612; http://dx.doi.org/10.1158/1535-7163.MCT-06-0511
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1641-1649
-
-
Han, W.1
Li, L.2
Qiu, S.3
Lu, Q.4
Pan, Q.5
Gu, Y.6
Luo, J.7
Hu, X.8
-
106
-
-
0042925297
-
Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1
-
12936978
-
X.Chen, L.Yang, N.Zhang, J.A.Turpin, R.W.Buckheit, C.Osterling, J.J.Oppenheim, O.M.Howard. Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1. Antimicrobial agents and chemotherapy 2003; 47:2810-6; PMID:12936978; http://dx.doi.org/10.1128/AAC.47.9.2810-2816.2003
-
(2003)
Antimicrobial agents and chemotherapy
, vol.47
, pp. 2810-2816
-
-
Chen, X.1
Yang, L.2
Zhang, N.3
Turpin, J.A.4
Buckheit, R.W.5
Osterling, C.6
Oppenheim, J.J.7
Howard, O.M.8
-
107
-
-
84878422114
-
Shikonin exerts anti-inflammatory effects in a murine model of lipopolysaccharide-induced acute lung injury by inhibiting the nuclear factor-kappaB signaling pathway
-
23651796
-
D.Liang, Y.Sun, Y.Shen, F.Li, X.Song, E.Zhou, F.Zhao, Z.Liu, Y.Fu, M.Guo, et al. Shikonin exerts anti-inflammatory effects in a murine model of lipopolysaccharide-induced acute lung injury by inhibiting the nuclear factor-kappaB signaling pathway. Int Immunopharmacol 2013; 16:475-80; PMID:23651796; http://dx.doi.org/10.1016/j.intimp.2013.04.020
-
(2013)
Int Immunopharmacol
, vol.16
, pp. 475-480
-
-
Liang, D.1
Sun, Y.2
Shen, Y.3
Li, F.4
Song, X.5
Zhou, E.6
Zhao, F.7
Liu, Z.8
Fu, Y.9
Guo, M.10
-
108
-
-
84889032526
-
The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis
-
24314238
-
Z.Fu, B.Deng, Y.Liao, L.Shan, F.Yin, Z.Wang, H.Zeng, D.Zuo, Y.Hua, Z.Cai. The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis. BMC Cancer 2013; 13:580; PMID:24314238; http://dx.doi.org/10.1186/1471-2407-13-580
-
(2013)
BMC Cancer
, vol.13
, pp. 580
-
-
Fu, Z.1
Deng, B.2
Liao, Y.3
Shan, L.4
Yin, F.5
Wang, Z.6
Zeng, H.7
Zuo, D.8
Hua, Y.9
Cai, Z.10
-
109
-
-
84921933135
-
Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells
-
25530098
-
N.Wada, Y.Kawano, S.Fujiwara, Y.Kikukawa, Y.Okuno, M.Tasaki, M.Ueda, Y.Ando, K.Yoshinaga, M.Ri, et al. Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells. Int J Oncol 2015; 46:963-72; PMID:25530098; http://dx.doi.org/10.3892/ijo.2014.2804
-
(2015)
Int J Oncol
, vol.46
, pp. 963-972
-
-
Wada, N.1
Kawano, Y.2
Fujiwara, S.3
Kikukawa, Y.4
Okuno, Y.5
Tasaki, M.6
Ueda, M.7
Ando, Y.8
Yoshinaga, K.9
Ri, M.10
-
110
-
-
84859771379
-
Molecular mechanisms of cisplatin resistance
-
21892204
-
L.Galluzzi, L.Senovilla, I.Vitale, J.Michels, I.Martins, O.Kepp, M.Castedo, G.Kroemer. Molecular mechanisms of cisplatin resistance. Oncogene 2012; 31:1869-83; PMID:21892204; http://dx.doi.org/10.1038/onc.2011.384
-
(2012)
Oncogene
, vol.31
, pp. 1869-1883
-
-
Galluzzi, L.1
Senovilla, L.2
Vitale, I.3
Michels, J.4
Martins, I.5
Kepp, O.6
Castedo, M.7
Kroemer, G.8
-
111
-
-
84928013139
-
Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma
-
25356865
-
K.E.McCabe, K.Bacos, D.Lu, J.R.Delaney, J.Axelrod, M.D.Potter, M.Vamos, V.Wong, N.D.Cosford, R.Xiang, et al. Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma. Cell Death Dis 2014; 5:e1496; PMID:25356865; http://dx.doi.org/10.1038/cddis.2014.448
-
(2014)
Cell Death Dis
, vol.5
, pp. e1496
-
-
McCabe, K.E.1
Bacos, K.2
Lu, D.3
Delaney, J.R.4
Axelrod, J.5
Potter, M.D.6
Vamos, M.7
Wong, V.8
Cosford, N.D.9
Xiang, R.10
-
112
-
-
36148966588
-
Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma
-
17827388
-
J.R.Cerhan, S.M.Ansell, Z.S.Fredericksen, N.E.Kay, M.Liebow, T.G.Call, A.Dogan, J.M.Cunningham, A.H.Wang, W.Liu-Mares, et al. Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma. Blood 2007; 110:4455-63; PMID:17827388; http://dx.doi.org/10.1182/blood-2007-05-088682
-
(2007)
Blood
, vol.110
, pp. 4455-4463
-
-
Cerhan, J.R.1
Ansell, S.M.2
Fredericksen, Z.S.3
Kay, N.E.4
Liebow, M.5
Call, T.G.6
Dogan, A.7
Cunningham, J.M.8
Wang, A.H.9
Liu-Mares, W.10
-
113
-
-
84862006553
-
Dysregulation of TNFalpha-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1
-
22157808
-
P.Liu, B.Xu, W.Shen, H.Zhu, W.Wu, Y.Fu, H.Chen, H.Dong, Y.Zhu, K.Miao, et al. Dysregulation of TNFalpha-induced necroptotic signaling in chronic lymphocytic leukemia:suppression of CYLD gene by LEF1. Leukemia 2012; 26:1293-300; PMID:22157808; http://dx.doi.org/10.1038/leu.2011.357
-
(2012)
Leukemia
, vol.26
, pp. 1293-1300
-
-
Liu, P.1
Xu, B.2
Shen, W.3
Zhu, H.4
Wu, W.5
Fu, Y.6
Chen, H.7
Dong, H.8
Zhu, Y.9
Miao, K.10
-
114
-
-
84937763512
-
New FDA-Approved Disease-Modifying Therapies for Multiple Sclerosis
-
25846320
-
C.English, J.J.Aloi. New FDA-Approved Disease-Modifying Therapies for Multiple Sclerosis. Clin Ther 2015; 37:691-715; PMID:25846320; http://dx.doi.org/10.1016/j.clinthera.2015.03.001
-
(2015)
Clin Ther
, vol.37
, pp. 691-715
-
-
English, C.1
Aloi, J.J.2
-
115
-
-
84871968824
-
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis
-
23180565
-
S.A.Saddoughi, S.Gencer, Y.K.Peterson, K.E.Ward, A.Mukhopadhyay, J.Oaks, J.Bielawski, Z.M.Szulc, R.J.Thomas, S.P.Selvam, et al. Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis. EMBO Mol Med 2013; 5:105-21; PMID:23180565; http://dx.doi.org/10.1002/emmm.201201283
-
(2013)
EMBO Mol Med
, vol.5
, pp. 105-121
-
-
Saddoughi, S.A.1
Gencer, S.2
Peterson, Y.K.3
Ward, K.E.4
Mukhopadhyay, A.5
Oaks, J.6
Bielawski, J.7
Szulc, Z.M.8
Thomas, R.J.9
Selvam, S.P.10
-
116
-
-
84929657840
-
FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells
-
25939952
-
L.Zhang, H.Wang, K.Ding, J.Xu. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicology letters 2015; 236:43-59; PMID:25939952; http://dx.doi.org/10.1016/j.toxlet.2015.04.015
-
(2015)
Toxicology letters
, vol.236
, pp. 43-59
-
-
Zhang, L.1
Wang, H.2
Ding, K.3
Xu, J.4
-
117
-
-
84962069613
-
Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity
-
27050509
-
T.L.Aaes, A.Kaczmarek, T.Delvaeye, B.De Craene, S.De Koker, L.Heyndrickx, I.Delrue, J.Taminau, B.Wiernicki, P.De Groote, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep 2016; 15:274-87; PMID:27050509; http://dx.doi.org/10.1016/j.celrep.2016.03.037
-
(2016)
Cell Rep
, vol.15
, pp. 274-287
-
-
Aaes, T.L.1
Kaczmarek, A.2
Delvaeye, T.3
De Craene, B.4
De Koker, S.5
Heyndrickx, L.6
Delrue, I.7
Taminau, J.8
Wiernicki, B.9
De Groote, P.10
-
118
-
-
84863227351
-
MicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia
-
22362744
-
H.Ye, X.Liu, M.Lv, Y.Wu, S.Kuang, J.Gong, P.Yuan, Z.Zhong, Q.Li, H.Jia, et al. MicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia. Nucleic Acids Res 2012; 40:5201-14; PMID:22362744; http://dx.doi.org/10.1093/nar/gks175
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 5201-5214
-
-
Ye, H.1
Liu, X.2
Lv, M.3
Wu, Y.4
Kuang, S.5
Gong, J.6
Yuan, P.7
Zhong, Z.8
Li, Q.9
Jia, H.10
-
119
-
-
77955992756
-
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
-
20797623
-
D.Iliopoulos, S.A.Jaeger, H.A.Hirsch, M.L.Bulyk, K.Struhl. STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell 2010; 39:493-506; PMID:20797623; http://dx.doi.org/10.1016/j.molcel.2010.07.023
-
(2010)
Mol Cell
, vol.39
, pp. 493-506
-
-
Iliopoulos, D.1
Jaeger, S.A.2
Hirsch, H.A.3
Bulyk, M.L.4
Struhl, K.5
-
120
-
-
84928751178
-
MicroRNAs in apoptosis, autophagy and necroptosis
-
25893379
-
Z.Su, Z.Yang, Y.Xu, Y.Chen, Q.Yu. MicroRNAs in apoptosis, autophagy and necroptosis. Oncotarget 2015; 6:8474-90; PMID:25893379; http://dx.doi.org/10.18632/oncotarget.3523
-
(2015)
Oncotarget
, vol.6
, pp. 8474-8490
-
-
Su, Z.1
Yang, Z.2
Xu, Y.3
Chen, Y.4
Yu, Q.5
|