Shikonin, a component of Chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 9, 2003, Pages 2810-2816

  Chen, Xin ^a   Yang, Lu ^c   Zhang, Ning ^b   Turpin, Jim A ^d   Buckheit, Robert W ^c   Osterling, Clay ^e   Oppenheim, Joost J ^b   Howard, O M Zack ^b  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c TherImmune Research Corporation   (United States)

^d HowPin International Consulting   (United States)

^e SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; BETA CHEMOKINE; CHEMOKINE RECEPTOR; COMPLEMENT COMPONENT C5A; FORMYLMETHIONYLLEUCYLPHENYLALANINE; G PROTEIN COUPLED RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; SHIKONIN; STROMAL CELL DERIVED FACTOR 1ALPHA;

ANTIINFLAMMATORY ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CALCIUM TRANSPORT; CHEMOTAXIS; CHINESE MEDICINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; HERBAL MEDICINE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IC 50; LITHOSPERMUM; LITHOSPERMUM ERYTHRORHIZON; MACROPHAGE; MOLECULAR WEIGHT; MONOCYTE; MONONUCLEAR CELL; PLANT ROOT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS STRAIN;

ANTI-HIV AGENTS; ANTI-INFLAMMATORY AGENTS; CALCIUM SIGNALING; CELL SURVIVAL; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; DOWN-REGULATION; DRUGS, CHINESE HERBAL; FLOW CYTOMETRY; HUMANS; NAPHTHOQUINONES; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 0042925297     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.9.2810-2816.2003     Document Type: Article

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