Shikonin exerts anti-inflammatory effects in a murine model of lipopolysaccharide-induced acute lung injury by inhibiting the nuclear factor-kappaB signaling pathway

International Immunopharmacology

Volumn 16, Issue 4, 2013, Pages 475-480

  Liang, Dejie ^a   Sun, Yong ^a   Shen, Yongbin ^b   Li, Fengyang ^a   Song, Xiaojing ^a   Zhou, Ershun ^a   Zhao, Fuyi ^a   Liu, Zhicheng ^a   Fu, Yunhe ^a   Guo, Mengyao ^a   Zhang, Naisheng ^a   Yang, Zhengtao ^a   Cao, Yongguo ^a  

^a JILIN UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Acute lung injury (ALI); Anti inflammatory; Nuclear factor kappaB (NF B); Shikonin Lipopolysaccharide (LPS)

Indexed keywords

DEXAMETHASONE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; SHIKONIN; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HISTOPATHOLOGY; LUNG LAVAGE; MACROPHAGE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PREMEDICATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THERAPY EFFECT; WESTERN BLOTTING;

ACUTE LUNG INJURY; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DISEASE MODELS, ANIMAL; LIPOPOLYSACCHARIDES; LITHOSPERMUM; LUNG; MALE; MICE; MICE, INBRED BALB C; NAPHTHOQUINONES; NF-KAPPA B; ORGAN SIZE; PLANT ROOTS; SIGNAL TRANSDUCTION;

EID: 84878422114     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.04.020     Document Type: Article

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