The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

Immunity

Volumn 39, Issue 3, 2013, Pages 443-453

  Murphy, James M ^a,b   Czabotar, Peter E ^a,b   Hildebrand, Joanne M ^a,b   Lucet, Isabelle S ^c   Zhang, Jian Guo ^a,b   Alvarez Diaz, Silvia ^a,b   Lewis, Rowena ^a,b   Lalaoui, Najoua ^a,b   Metcalf, Donald ^a,b   Webb, Andrew I ^a,b   Young, Samuel N ^a,b   Varghese, Leila N ^a,b   Tannahill, Gillian M ^a,b   Hatchell, Esme C ^a,b   Majewski, Ian J ^a,b   Okamoto, Toru ^a,b   Dobson, Renwick C J ^b,d   Hilton, Douglas J ^a,b   Babon, Jeffrey J ^a,b   Nicola, Nicos A ^a,b   Strasser, Andreas ^a,b   Silke, John ^a,b   Alexander, Warren S ^a,b   more..

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF CANTERBURY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SERINE THREONINE KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE MUTATION; MIXED LINEAGE KINASE DOMAIN LIKE; MOLECULAR MECHANICS; MOUSE; MUTATION; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; APOPTOSIS; CATALYTIC DOMAIN; CELL LINE; CRYSTALLOGRAPHY, X-RAY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NECROSIS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN KINASES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTORS;

EID: 84884308522     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2013.06.018     Document Type: Article

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