메뉴 건너뛰기




Volumn 23, Issue 3, 2016, Pages 369-379

Ferroptosis: Process and function

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; ARTESUNATE; BUTHIONINESULFOXIMINE; CHONDROITIN SULFATE IRON; CYSTEINYL TRNA SYNTHETASE; ERASTIN; FERROPTOSIS INDUCING AGENT; HEAT SHOCK PROTEIN 27; IRON; IRON CHELATING AGENT; LANPERISONE; LYASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; PARACETAMOL; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; PROTEIN; PROTEIN INHIBITOR; PROTEIN P53; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RSL3; RSL5; SALAZOSULFAPYRIDINE; SORAFENIB; TFR1 PROTEIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 2; VOLTAGE DEPENDENT ANION CHANNEL 3; ZILEUTON;

EID: 84957429081     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2015.158     Document Type: Review
Times cited : (2693)

References (47)
  • 2
    • 0037932865 scopus 로고    scopus 로고
    • Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
    • Dolma S, Lessnick SL, Hahn WC, Stockwell BR. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell 2003; 3: 285-296.
    • (2003) Cancer Cell , vol.3 , pp. 285-296
    • Dolma, S.1    Lessnick, S.L.2    Hahn, W.C.3    Stockwell, B.R.4
  • 3
    • 40849085503 scopus 로고    scopus 로고
    • Synthetic lethal screening identifies compounds activating irondependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells
    • Yang WS, Stockwell BR. Synthetic lethal screening identifies compounds activating irondependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. Chem Biol 2008; 15: 234-245.
    • (2008) Chem Biol , vol.15 , pp. 234-245
    • Yang, W.S.1    Stockwell, B.R.2
  • 4
    • 34250372956 scopus 로고    scopus 로고
    • RAS-RAFMEK-dependent oxidative cell death involving voltage-dependent anion channels
    • Yagoda N, von Rechenberg M, Zaganjor E, Bauer AJ, Yang WS, Fridman DJ et al. RAS-RAFMEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature 2007; 447: 864-868.
    • (2007) Nature , vol.447 , pp. 864-868
    • Yagoda, N.1    Von Rechenberg, M.2    Zaganjor, E.3    Bauer, A.J.4    Yang, W.S.5    Fridman, D.J.6
  • 7
    • 84901323900 scopus 로고    scopus 로고
    • Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis
    • Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M et al. Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis. eLife 2014; 3: e02523.
    • (2014) ELife , vol.3 , pp. e02523
    • Dixon, S.J.1    Patel, D.N.2    Welsch, M.3    Skouta, R.4    Lee, E.D.5    Hayano, M.6
  • 9
    • 84862939534 scopus 로고    scopus 로고
    • Identification of simple compounds with microtubule-binding activity that inhibit cancer cell growth with high potency
    • Yang WS, Shimada K, Delva D, Patel M, Ode E, Skouta R et al. Identification of simple compounds with microtubule-binding activity that inhibit cancer cell growth with high potency. ACS Med Chem Lett 2012; 3: 35-38.
    • (2012) ACS Med Chem Lett , vol.3 , pp. 35-38
    • Yang, W.S.1    Shimada, K.2    Delva, D.3    Patel, M.4    Ode, E.5    Skouta, R.6
  • 10
  • 11
    • 0030715268 scopus 로고    scopus 로고
    • Effects of a new centrally acting muscle relaxant, NK433 (lanperisone hydrochloride) on spinal reflexes
    • Sakitama K, Ozawa Y, Aoto N, Tomita H, Ishikawa M. Effects of a new centrally acting muscle relaxant, NK433 (lanperisone hydrochloride) on spinal reflexes. Eur J Pharmacol 1997; 337: 175-187.
    • (1997) Eur J Pharmacol , vol.337 , pp. 175-187
    • Sakitama, K.1    Ozawa, Y.2    Aoto, N.3    Tomita, H.4    Ishikawa, M.5
  • 13
    • 0034772516 scopus 로고    scopus 로고
    • Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)-cystine transporter: A new action for an old drug
    • Gout PW, Buckley AR, Simms CR, Bruchovsky N. Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)-cystine transporter: a new action for an old drug. Leukemia 2001; 15: 1633-1640.
    • (2001) Leukemia , vol.15 , pp. 1633-1640
    • Gout, P.W.1    Buckley, A.R.2    Simms, C.R.3    Bruchovsky, N.4
  • 14
    • 84919432703 scopus 로고    scopus 로고
    • The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells
    • Louandre C, Marcq I, Bouhlal H, Lachaier E, Godin C, Saidak Z et al. The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells. Cancer Lett 2015; 356: 971-977.
    • (2015) Cancer Lett , vol.356 , pp. 971-977
    • Louandre, C.1    Marcq, I.2    Bouhlal, H.3    Lachaier, E.4    Godin, C.5    Saidak, Z.6
  • 16
    • 84916241447 scopus 로고    scopus 로고
    • Sorafenib induces ferroptosis in human cancer cell lines originating from different solid tumors
    • Lachaier E, Louandre C, Godin C, Saidak Z, Baert M, Diouf M et al. Sorafenib induces ferroptosis in human cancer cell lines originating from different solid tumors. Anticancer Res 2014; 34: 6417-6422.
    • (2014) Anticancer Res , vol.34 , pp. 6417-6422
    • Lachaier, E.1    Louandre, C.2    Godin, C.3    Saidak, Z.4    Baert, M.5    Diouf, M.6
  • 17
    • 84952639010 scopus 로고    scopus 로고
    • Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
    • Sep 24 [Epub ahead of print]
    • Sun X, Ou Z, Chen R, Niu X, Chen, Kang R et al. Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells. Hepatology 2015 Sep 24. doi: 10.1002/hep.28251. [Epub ahead of print].
    • (2015) Hepatology
    • Sun, X.1    Ou, Z.2    Chen, R.3    Niu, X.4    Chen Kang, R.5
  • 18
    • 84957431913 scopus 로고    scopus 로고
    • Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells
    • Nils Eling, Lukas Reuter, Hazin John, Hamacher-Brady Anne, Brady NR. Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells. Oncoscience 2015; 2: 517-532.
    • (2015) Oncoscience , vol.2 , pp. 517-532
    • Eling, N.1    Reuter, L.2    John, H.3    Anne, H.-B.4    Brady, N.R.5
  • 19
    • 84941550824 scopus 로고    scopus 로고
    • Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
    • Ooko E, Saeed ME, Kadioglu O, Sarvi S, Colak M, Elmasaoudi K et al. Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells. Phytomedicine 2015; 22: 1045-1054.
    • (2015) Phytomedicine , vol.22 , pp. 1045-1054
    • Ooko, E.1    Saeed, M.E.2    Kadioglu, O.3    Sarvi, S.4    Colak, M.5    Elmasaoudi, K.6
  • 20
    • 84890922670 scopus 로고    scopus 로고
    • The role of iron and reactive oxygen species in cell death
    • Dixon SJ, Stockwell BR. The role of iron and reactive oxygen species in cell death. Nat Chem Biol 2014; 10: 9-17.
    • (2014) Nat Chem Biol , vol.10 , pp. 9-17
    • Dixon, S.J.1    Stockwell, B.R.2
  • 21
    • 84937119776 scopus 로고    scopus 로고
    • Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death
    • Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M et al. Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death. ACS Chem Biol 2015; 10: 1604-1609.
    • (2015) ACS Chem Biol , vol.10 , pp. 1604-1609
    • Dixon, S.J.1    Winter, G.E.2    Musavi, L.S.3    Lee, E.D.4    Snijder, B.5    Rebsamen, M.6
  • 22
    • 84897059782 scopus 로고    scopus 로고
    • Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models
    • Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K et al. Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. J Am Chem Soc 2014; 136: 4551-4556.
    • (2014) J Am Chem Soc , vol.136 , pp. 4551-4556
    • Skouta, R.1    Dixon, S.J.2    Wang, J.3    Dunn, D.E.4    Orman, M.5    Shimada, K.6
  • 23
    • 85024121807 scopus 로고    scopus 로고
    • The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents
    • May 26 [Epub ahead of print]
    • Yu Y, Xie Y, Cao L, Yang L, Yang M, Lotze MT et al. The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents. Mol Cell Oncol 2015 May 26. doi:10.1080/23723556.2015.1054549. [Epub ahead of print].
    • (2015) Mol Cell Oncol
    • Yu, Y.1    Xie, Y.2    Cao, L.3    Yang, L.4    Yang, M.5    Lotze, M.T.6
  • 25
    • 84876936843 scopus 로고    scopus 로고
    • Voltage-dependent anion channels modulate mitochondrial metabolism in cancer cells: Regulation by free tubulin and erastin
    • Maldonado EN, Sheldon KL, DeHart DN, Patnaik J, Manevich Y, Townsend DM et al. Voltage-dependent anion channels modulate mitochondrial metabolism in cancer cells: regulation by free tubulin and erastin. J Biol Chem 2013; 288: 11920-11929.
    • (2013) J Biol Chem , vol.288 , pp. 11920-11929
    • Maldonado, E.N.1    Sheldon, K.L.2    DeHart, D.N.3    Patnaik, J.4    Manevich, Y.5    Townsend, D.M.6
  • 27
    • 84926387317 scopus 로고    scopus 로고
    • Ferroptosis as a p53-mediated activity during tumour suppression
    • Jiang L, Kon N, Li T, Wang SJ, Su T, Hibshoosh H et al. Ferroptosis as a p53-mediated activity during tumour suppression. Nature 2015; 520: 57-62.
    • (2015) Nature , vol.520 , pp. 57-62
    • Jiang, L.1    Kon, N.2    Li, T.3    Wang, S.J.4    Su, T.5    Hibshoosh, H.6
  • 29
    • 84934269293 scopus 로고    scopus 로고
    • Oncogenic RAS mutants confer resistance of RMS13 rhabdomyosarcoma cells to oxidative stress-induced ferroptotic cell death
    • Schott C, Graab U, Cuvelier N, Hahn H, Fulda S. Oncogenic RAS mutants confer resistance of RMS13 rhabdomyosarcoma cells to oxidative stress-induced ferroptotic cell death. Front Oncol 2015; 5: 131.
    • (2015) Front Oncol , vol.5 , pp. 131
    • Schott, C.1    Graab, U.2    Cuvelier, N.3    Hahn, H.4    Fulda, S.5
  • 30
    • 84937525519 scopus 로고    scopus 로고
    • Glutaminolysis and transferrin regulate ferroptosis
    • Gao M, Monian P, Quadri N, Ramasamy R, Jiang X. Glutaminolysis and transferrin regulate ferroptosis. Mol Cell 2015; 59: 298-308.
    • (2015) Mol Cell , vol.59 , pp. 298-308
    • Gao, M.1    Monian, P.2    Quadri, N.3    Ramasamy, R.4    Jiang, X.5
  • 31
    • 84861973567 scopus 로고    scopus 로고
    • Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
    • Li T, Kon N, Jiang L, Tan M, Ludwig T, Zhao Y et al. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell 2012; 149: 1269-1283.
    • (2012) Cell , vol.149 , pp. 1269-1283
    • Li, T.1    Kon, N.2    Jiang, L.3    Tan, M.4    Ludwig, T.5    Zhao, Y.6
  • 32
    • 84934783188 scopus 로고    scopus 로고
    • Murinedouble minute-2 prevents p53-overactivation-related cell death (podoptosis) of podocytes
    • Thomasova D, Bruns HA, Kretschmer V, Ebrahim M, Romoli S, Liapis H et al. Murinedouble minute-2 prevents p53-overactivation-related cell death (podoptosis) of podocytes. J AmSoc Nephrol 2014; 26: 1513-1523.
    • (2014) J AmSoc Nephrol , vol.26 , pp. 1513-1523
    • Thomasova, D.1    Bruns, H.A.2    Kretschmer, V.3    Ebrahim, M.4    Romoli, S.5    Liapis, H.6
  • 33
    • 84954379174 scopus 로고    scopus 로고
    • Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation
    • Jul 17 [Epub ahead of print]
    • Hayano M, Yang WS, Corn CK, Pagano NC, Stockwell BR. Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation. Cell Death Differ 2015 Jul 17. doi: 10.1038/cdd.2015.93. [Epub ahead of print].
    • (2015) Cell Death Differ
    • Hayano, M.1    Yang, W.S.2    Corn, C.K.3    Pagano, N.C.4    Stockwell, B.R.5
  • 34
    • 84947786974 scopus 로고    scopus 로고
    • Ablation of ferroptosis inhibitor glutathione peroxidase 4 in neurons results in rapid motor neuron degeneration and paralysis
    • Chen L, Hambright WS, Na R, Ran Q. Ablation of ferroptosis inhibitor glutathione peroxidase 4 in neurons results in rapid motor neuron degeneration and paralysis. J Biol Chem 2015; 290: 28097-28106.
    • (2015) J Biol Chem , vol.290 , pp. 28097-28106
    • Chen, L.1    Hambright, W.S.2    Na, R.3    Ran, Q.4
  • 35
    • 84957447338 scopus 로고    scopus 로고
    • Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
    • Oct 13. pii: blood-2015-06-654194. [Epub ahead of print]
    • Canli Ö, Alanku? YB, Grootjans S, Vegi N, Hültner L, Hoppe PS et al. Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors. Blood 2015 Oct 13. pii: blood-2015-06-654194. [Epub ahead of print].
    • (2015) Blood
    • Canli, O.1    Alanku, Y.B.2    Grootjans, S.3    Vegi, N.4    Hültner, L.5    Hoppe, P.S.6
  • 36
    • 84947035915 scopus 로고    scopus 로고
    • HSPB1 as a novel regulator of ferroptotic cancer cell death
    • Sun X, Ou Z, Xie M, Kang R, Fan Y, Niu X et al. HSPB1 as a novel regulator of ferroptotic cancer cell death. Oncogene 2015; 34: 5617-5625.
    • (2015) Oncogene , vol.34 , pp. 5617-5625
    • Sun, X.1    Ou, Z.2    Xie, M.3    Kang, R.4    Fan, Y.5    Niu, X.6
  • 37
    • 84943390843 scopus 로고    scopus 로고
    • Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
    • Kwon MY, Park E, Lee SJ, Chung SW. Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death. Oncotarget 2015; 6: 24393-24403.
    • (2015) Oncotarget , vol.6 , pp. 24393-24403
    • Kwon, M.Y.1    Park, E.2    Lee, S.J.3    Chung, S.W.4
  • 39
    • 0028842212 scopus 로고
    • Sensitive colorimetric cytotoxicity measurement using alarmar blue
    • Page B, Page M. Sensitive colorimetric cytotoxicity measurement using alarmar blue. Oncol Rep 1995; 2: 59-61.
    • (1995) Oncol Rep , vol.2 , pp. 59-61
    • Page, B.1    Page, M.2
  • 41
    • 84940944514 scopus 로고    scopus 로고
    • The 5-lipoxygenase inhibitor zileuton confers neuroprotection against glutamate oxidative damage by inhibiting ferroptosis
    • Liu Y, Wang W, Li Y, Xiao Y, Cheng J, Jia J. The 5-lipoxygenase inhibitor zileuton confers neuroprotection against glutamate oxidative damage by inhibiting ferroptosis. Biol Pharm Bull 2015; 38: 1234-1239.
    • (2015) Biol Pharm Bull , vol.38 , pp. 1234-1239
    • Liu, Y.1    Wang, W.2    Li, Y.3    Xiao, Y.4    Cheng, J.5    Jia, J.6
  • 42
    • 84921647344 scopus 로고    scopus 로고
    • Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-gamma-lyase function
    • Chen L, Li X, Liu L, Yu B, Xue Y, Liu Y. Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-gamma-lyase function. Oncol Rep 2015; 33: 1465-1474.
    • (2015) Oncol Rep , vol.33 , pp. 1465-1474
    • Chen, L.1    Li, X.2    Liu, L.3    Yu, B.4    Xue, Y.5    Liu, Y.6
  • 43
    • 84874038196 scopus 로고    scopus 로고
    • Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells
    • Yamaguchi H, Hsu JL, Chen CT, Wang YN, Hsu MC, Chang SS et al. Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells. Clin Cancer Res 2013; 19: 845-854.
    • (2013) Clin Cancer Res , vol.19 , pp. 845-854
    • Yamaguchi, H.1    Hsu, J.L.2    Chen, C.T.3    Wang, Y.N.4    Hsu, M.C.5    Chang, S.S.6
  • 44
    • 84898809189 scopus 로고    scopus 로고
    • Cellular protection using Flt3 and PI3Kalpha inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity
    • Kang Y, Tiziani S, Park G, Kaul M, Paternostro G. Cellular protection using Flt3 and PI3Kalpha inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity. Nat Commun 2014; 5: 3672.
    • (2014) Nat Commun , vol.5 , pp. 3672
    • Kang, Y.1    Tiziani, S.2    Park, G.3    Kaul, M.4    Paternostro, G.5
  • 46
    • 84255210700 scopus 로고    scopus 로고
    • Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012
    • Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV et al. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 2012 19: 107-120.
    • (2012) Cell Death Differ , vol.19 , pp. 107-120
    • Galluzzi, L.1    Vitale, I.2    Abrams, J.M.3    Alnemri, E.S.4    Baehrecke, E.H.5    Blagosklonny, M.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.