FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells

Toxicology Letters

Volumn 236, Issue 1, 2015, Pages 43-59

  Zhang, Li ^a   Wang, Handong ^a   Ding, Ke ^a   Xu, Jianguo ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; FTY720; Glioblastoma; Necroptosis

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; AUTOPHAGY PROTEIN 12; AUTOPHAGY PROTEIN 3; AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; BECLIN 1; CASPASE 3; CASPASE 8; CYTOCHROME C; FINGOLIMOD; LIPOCORTIN 5; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; P70S6 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN 1; RECEPTOR INTERACTING PROTEIN 3; SHORT HAIRPIN RNA; SPHINGOSINE 1 PHOSPHATE RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; BIOLOGICAL MARKER; MEMBRANE PROTEIN; PROPANEDIOL DERIVATIVE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, HUMAN; RIPK3 PROTEIN, HUMAN; SPHINGOSINE; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL VIABILITY; CYTOTOXICITY; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; MALE; MOUSE; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; GENETICS; GLIOBLASTOMA; METABOLISM; NECROSIS; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BIOLOGICAL MARKERS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIOBLASTOMA; HUMANS; MALE; MEMBRANE PROTEINS; MICE, NUDE; NECROSIS; NEOPLASM PROTEINS; PROPYLENE GLYCOLS; REACTIVE OXYGEN SPECIES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SPHINGOSINE; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84929657840     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.04.015     Document Type: Article

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