-
2
-
-
85027948565
-
International Society of Neuropathology-Haarlem consensus guidelines for nervous system tumor classification and grading
-
Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, et al. 2014. International Society Of Neuropathology-Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathol. 24:429-35
-
(2014)
Brain Pathol.
, vol.24
, pp. 429-435
-
-
Louis, D.N.1
Perry, A.2
Burger, P.3
Ellison, D.W.4
Reifenberger, G.5
-
3
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ,WellerM, Fisher B, et al. 2005. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352:987-96
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
-
4
-
-
84894194756
-
Bevacizumab plus radiotherapytemozolomide for newly diagnosed glioblastoma
-
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, et al. 2014. Bevacizumab plus radiotherapytemozolomide for newly diagnosed glioblastoma. N. Engl. J. Med. 370:709-22
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 709-722
-
-
Chinot, O.L.1
Wick, W.2
Mason, W.3
Henriksson, R.4
Saran, F.5
-
5
-
-
84894114159
-
A randomized trial of bevacizumab for newly diagnosed glioblastoma
-
Gilbert MR, Dignam JJ, Armstrong TS, Wefel JS, Blumenthal DT, et al. 2014. A randomized trial of bevacizumab for newly diagnosed glioblastoma. N. Engl. J. Med. 370:699-708
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 699-708
-
-
Gilbert, M.R.1
Dignam, J.J.2
Armstrong, T.S.3
Wefel, J.S.4
Blumenthal, D.T.5
-
6
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, et al. 2001. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 344:783-92
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
-
7
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, et al. 2011. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 364:2507-16
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
-
8
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, et al. 2001. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. 344:1031-37
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
-
9
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, et al. 2004. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 350:2129-39
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
-
10
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, et al. 2010. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N. Engl. J. Med. 363:1693-703
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
-
11
-
-
84932628860
-
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
-
Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, et al. 2015. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N. Engl. J. Med. 372:2481-98
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 2481-2498
-
-
Cancer Genome Atlas Research Network1
Brat, D.J.2
Verhaak, R.G.3
Aldape, K.D.4
Yung, W.K.5
-
12
-
-
84859847164
-
Emerging insights into the molecular and cellular basis of glioblastoma
-
Dunn GP, Rinne ML, Wykosky J, Genovese G, Quayle SN, et al. 2012. Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev. 26:756-84
-
(2012)
Genes Dev.
, vol.26
, pp. 756-784
-
-
Dunn, G.P.1
Rinne, M.L.2
Wykosky, J.3
Genovese, G.4
Quayle, S.N.5
-
13
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, et al. 2013. The somatic genomic landscape of glioblastoma. Cell 155:462-77
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.2
McKenna, A.3
Campos, B.4
Noushmehr, H.5
-
14
-
-
0025114687
-
Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas
-
Sugawa N, Ekstrand AJ, James CD, Collins VP. 1990. Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. PNAS 87:8602-6
-
(1990)
PNAS
, vol.87
, pp. 8602-8606
-
-
Sugawa, N.1
Ekstrand, A.J.2
James, C.D.3
Collins, V.P.4
-
15
-
-
0029146954
-
EGFR gene amplification-rearrangement in human glioblastomas
-
Schwechheimer K, Huang S, Cavenee WK. 1995. EGFR gene amplification-rearrangement in human glioblastomas. Int. J. Cancer 62:145-48
-
(1995)
Int. J. Cancer
, vol.62
, pp. 145-148
-
-
Schwechheimer, K.1
Huang, S.2
Cavenee, W.K.3
-
16
-
-
2442676505
-
Predominant expression of mutant EGFR (EGFRvIII) is rare in primary glioblastomas
-
BiernatW,Huang H, YokooH, Kleihues P, OhgakiH. 2004. Predominant expression of mutant EGFR (EGFRvIII) is rare in primary glioblastomas. Brain Pathol. 14:131-36
-
(2004)
Brain Pathol.
, vol.14
, pp. 131-136
-
-
Biernat, W.1
Huang, H.2
Yokoo, H.3
Kleihues, P.4
Ohgaki, H.5
-
17
-
-
7144261725
-
The class III variant of the epidermal growth factor receptor (EGFRvIII): Characterization and utilization as an immunotherapeutic target
-
Wikstrand CJ, Reist CJ, Archer GE, Zalutsky MR, Bigner DD. 1998. The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target. J. Neurovirol. 4:148-58
-
(1998)
J. Neurovirol.
, vol.4
, pp. 148-158
-
-
Wikstrand, C.J.1
Reist, C.J.2
Archer, G.E.3
Zalutsky, M.R.4
Bigner, D.D.5
-
18
-
-
84928590179
-
Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma
-
Furnari FB, Cloughesy TF, Cavenee WK,Mischel PS. 2015. Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma. Nat. Rev. Cancer 15:302-10
-
(2015)
Nat. Rev. Cancer
, vol.15
, pp. 302-310
-
-
Furnari, F.B.1
Cloughesy, T.F.2
Cavenee, W.K.3
Mischel, P.S.4
-
19
-
-
83455176258
-
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
-
Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, et al. 2011. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell 20:810-17
-
(2011)
Cancer Cell
, vol.20
, pp. 810-817
-
-
Snuderl, M.1
Fazlollahi, L.2
Le, L.P.3
Nitta, M.4
Zhelyazkova, B.H.5
-
20
-
-
84905447834
-
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing
-
Francis JM, Zhang CZ, Maire CL, Jung J, Manzo VE, et al. 2014. EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing. Cancer Discov. 4:956-71
-
(2014)
Cancer Discov.
, vol.4
, pp. 956-971
-
-
Francis, J.M.1
Zhang, C.Z.2
Maire, C.L.3
Jung, J.4
Manzo, V.E.5
-
21
-
-
84902668801
-
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
-
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, et al. 2014. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science 344:1396-401
-
(2014)
Science
, vol.344
, pp. 1396-1401
-
-
Patel, A.P.1
Tirosh, I.2
Trombetta, J.J.3
Shalek, A.K.4
Gillespie, S.M.5
-
22
-
-
84874598318
-
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
-
Sottoriva A, Spiteri I, Piccirillo SG, Touloumis A, Collins VP, et al. 2013. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. PNAS 110:4009-14
-
(2013)
PNAS
, vol.110
, pp. 4009-4014
-
-
Sottoriva, A.1
Spiteri, I.2
Piccirillo, S.G.3
Touloumis, A.4
Collins, V.P.5
-
23
-
-
84906673966
-
MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma
-
Gill BJ, Pisapia DJ, Malone HR, Goldstein H, Lei L, et al. 2014. MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma. PNAS 111:12550-55
-
(2014)
PNAS
, vol.111
, pp. 12550-12555
-
-
Gill, B.J.1
Pisapia, D.J.2
Malone, H.R.3
Goldstein, H.4
Lei, L.5
-
24
-
-
84892775264
-
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA
-
Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, et al. 2014. Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA. Science 343(6166):72-76
-
(2014)
Science
, vol.343
, Issue.6166
, pp. 72-76
-
-
Nathanson, D.A.1
Gini, B.2
Mottahedeh, J.3
Visnyei, K.4
Koga, T.5
-
25
-
-
84873347374
-
The tumorigenic FGFR3-TACC3 gene fusion escapes MIR-99a regulation in glioblastoma
-
Parker BC, Annala MJ, Cogdell DE, Granberg KJ, Sun Y, et al. 2013. The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma. J. Clin. Investig. 123:855-65
-
(2013)
J. Clin. Investig.
, vol.123
, pp. 855-865
-
-
Parker, B.C.1
Annala, M.J.2
Cogdell, D.E.3
Granberg, K.J.4
Sun, Y.5
-
26
-
-
84865805666
-
Transforming fusions of FGFR and TACC genes in human glioblastoma
-
Singh D, Chan JM, Zoppoli P, Niola F, Sullivan R, et al. 2012. Transforming fusions of FGFR and TACC genes in human glioblastoma. Science 337:1231-35
-
(2012)
Science
, vol.337
, pp. 1231-1235
-
-
Singh, D.1
Chan, J.M.2
Zoppoli, P.3
Niola, F.4
Sullivan, R.5
-
27
-
-
84884996623
-
The integrated landscape of driver genomic alterations in glioblastoma
-
Frattini V, Trifonov V, Chan JM, Castano A, Lia M, et al. 2013. The integrated landscape of driver genomic alterations in glioblastoma. Nat. Genet. 45:1141-49
-
(2013)
Nat. Genet.
, vol.45
, pp. 1141-1149
-
-
Frattini, V.1
Trifonov, V.2
Chan, J.M.3
Castano, A.4
Lia, M.5
-
29
-
-
84877593565
-
De-repression ofPDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients
-
AkhavanD,Pourzia AL, Nourian AA, WilliamsKJ, NathansonD, et al. 2013. De-repression ofPDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients. Cancer Discov. 3:534-47
-
(2013)
Cancer Discov.
, vol.3
, pp. 534-547
-
-
Akhavan, D.1
Pourzia, A.L.2
Nourian, A.A.3
Williams, K.J.4
Nathanson, D.5
-
30
-
-
84892775264
-
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA
-
Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, et al. 2014. Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA. Science 343:72-76
-
(2014)
Science
, vol.343
, pp. 72-76
-
-
Nathanson, D.A.1
Gini, B.2
Mottahedeh, J.3
Visnyei, K.4
Koga, T.5
-
31
-
-
84861760527
-
Differential sensitivity of gliomaversus lung cancer-specific EGFR mutations to EGFR kinase inhibitors
-
Vivanco I, Robins HI, Rohle D, Campos C, Grommes C, et al. 2012. Differential sensitivity of gliomaversus lung cancer-specific EGFR mutations to EGFR kinase inhibitors. Cancer Discov. 2:458-71
-
(2012)
Cancer Discov.
, vol.2
, pp. 458-471
-
-
Vivanco, I.1
Robins, H.I.2
Rohle, D.3
Campos, C.4
Grommes, C.5
-
32
-
-
84874645357
-
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation
-
Morris LG, Kaufman AM, Gong Y, Ramaswami D, Walsh LA, et al. 2013. Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. Nat. Genet. 45:253-61
-
(2013)
Nat. Genet.
, vol.45
, pp. 253-261
-
-
Morris, L.G.1
Kaufman, A.M.2
Gong, Y.3
Ramaswami, D.4
Walsh, L.A.5
-
33
-
-
84878543522
-
An aberrant transcription factor network essential forWnt signaling and stem cell maintenance in glioblastoma
-
Rheinbay E, Suva ML,Gillespie SM,WakimotoH, Patel AP, et al. 2013. An aberrant transcription factor network essential forWnt signaling and stem cell maintenance in glioblastoma. Cell Rep. 3:1567-79
-
(2013)
Cell Rep.
, vol.3
, pp. 1567-1579
-
-
Rheinbay, E.1
Suva, M.L.2
Gillespie, S.M.3
Wakimoto, H.4
Patel, A.P.5
-
34
-
-
84899524502
-
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
-
Suva ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, et al. 2014. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell 157:580-94
-
(2014)
Cell
, vol.157
, pp. 580-594
-
-
Suva, M.L.1
Rheinbay, E.2
Gillespie, S.M.3
Patel, A.P.4
Wakimoto, H.5
-
35
-
-
84930677573
-
The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer
-
Bell RJ, Rube HT, Kreig A, Mancini A, Fouse SD, et al. 2015. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. Science 348(6238):1036-39
-
(2015)
Science
, vol.348
, Issue.6238
, pp. 1036-1039
-
-
Bell, R.J.1
Rube, H.T.2
Kreig, A.3
Mancini, A.4
Fouse, S.D.5
-
36
-
-
84862777348
-
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, et al. 2012. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482:226-31
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
Jones, D.T.4
Pfaff, E.5
-
37
-
-
84868625787
-
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
-
Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, et al. 2012. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget 3:709-22
-
(2012)
Oncotarget
, vol.3
, pp. 709-722
-
-
Jiao, Y.1
Killela, P.J.2
Reitman, Z.J.3
Rasheed, A.B.4
Heaphy, C.M.5
-
38
-
-
84899526966
-
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
-
Wu G, Diaz AK, Paugh BS, Rankin SL, Ju B, et al. 2014. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nat. Genet. 46:444-50
-
(2014)
Nat. Genet.
, vol.46
, pp. 444-450
-
-
Wu, G.1
Diaz, A.K.2
Paugh, B.S.3
Rankin, S.L.4
Ju, B.5
-
39
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, et al. 2008. An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-12
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
-
40
-
-
80052713548
-
Genetic profile of astrocytic and oligodendroglial gliomas
-
Ohgaki H, Kleihues P. 2011. Genetic profile of astrocytic and oligodendroglial gliomas. Brain Tumor Pathol. 28:177-83
-
(2011)
Brain Tumor Pathol.
, vol.28
, pp. 177-183
-
-
Ohgaki, H.1
Kleihues, P.2
-
41
-
-
79251601011
-
A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: Chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53
-
Camelo-Piragua S, Jansen M, Ganguly A, Kim JC, Cosper AK, et al. 2011. A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: Chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53. J. Neuropathol. Exp. Neurol. 70:110-15
-
(2011)
J. Neuropathol. Exp. Neurol.
, vol.70
, pp. 110-115
-
-
Camelo-Piragua, S.1
Jansen, M.2
Ganguly, A.3
Kim, J.C.4
Cosper, A.K.5
-
42
-
-
84864050066
-
IDH mutations as an early and consistent marker in low-grade astrocytomas WHO grade II and their consecutive secondary high-grade gliomas
-
JuratliTA, KirschM, Robel K, Soucek S, Geiger K, et al. 2012. IDH mutations as an early and consistent marker in low-grade astrocytomas WHO grade II and their consecutive secondary high-grade gliomas. J. Neuro-Oncol. 108:403-10
-
(2012)
J. Neuro-Oncol.
, vol.108
, pp. 403-410
-
-
Juratli, T.A.1
Kirsch, M.2
Robel, K.3
Soucek, S.4
Geiger, K.5
-
43
-
-
84872788316
-
Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
-
Kannan K, Inagaki A, Silber J, Gorovets D, Zhang J, et al. 2012. Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma. Oncotarget 3:1194-203
-
(2012)
Oncotarget
, vol.3
, pp. 1194-1203
-
-
Kannan, K.1
Inagaki, A.2
Silber, J.3
Gorovets, D.4
Zhang, J.5
-
44
-
-
84871020024
-
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
-
Liu XY, Gerges N, Korshunov A, Sabha N, Khuong-Quang DA, et al. 2012. Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations. Acta Neuropathol. 124:615-25
-
(2012)
Acta Neuropathol.
, vol.124
, pp. 615-625
-
-
Liu, X.Y.1
Gerges, N.2
Korshunov, A.3
Sabha, N.4
Khuong-Quang, D.A.5
-
45
-
-
84929712325
-
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma
-
Reuss DE, Sahm F, Schrimpf D, Wiestler B, Capper D, et al. 2015. ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. Acta Neuropathol. 129:133-46
-
(2015)
Acta Neuropathol.
, vol.129
, pp. 133-146
-
-
Reuss, D.E.1
Sahm, F.2
Schrimpf, D.3
Wiestler, B.4
Capper, D.5
-
46
-
-
84887123502
-
The alternative lengthening of telomere phenotype is significantly associated with loss ofATRXexpression in high-grade pediatric and adult astrocytomas: A multi-institutional study of 214 astrocytomas
-
AbedalthagafiM, Phillips JJ, Kim GE, Mueller S,Haas-Kogen DA, et al. 2013. The alternative lengthening of telomere phenotype is significantly associated with loss ofATRXexpression in high-grade pediatric and adult astrocytomas: A multi-institutional study of 214 astrocytomas. Mod. Pathol. 26:1425-32
-
(2013)
Mod. Pathol.
, vol.26
, pp. 1425-1432
-
-
Abedalthagafi, M.1
Phillips, J.J.2
Kim, G.E.3
Mueller, S.4
Haas-Kogen, D.A.5
-
47
-
-
84892590846
-
Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system
-
Koelsche C, Sahm F, Capper D, Reuss D, Sturm D, et al. 2013. Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system. Acta Neuropathol. 126:907-15
-
(2013)
Acta Neuropathol.
, vol.126
, pp. 907-915
-
-
Koelsche, C.1
Sahm, F.2
Capper, D.3
Reuss, D.4
Sturm, D.5
-
48
-
-
84886712846
-
Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas
-
Fontebasso AM, Schwartzentruber J, Khuong-Quang DA, Liu XY, Sturm D, et al. 2013. Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas. Acta Neuropathol. 125:659-69
-
(2013)
Acta Neuropathol.
, vol.125
, pp. 659-669
-
-
Fontebasso, A.M.1
Schwartzentruber, J.2
Khuong-Quang, D.A.3
Liu, X.Y.4
Sturm, D.5
-
49
-
-
84879475201
-
BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults
-
Chi AS, Batchelor TT, Yang D, Dias-Santagata D, Borger DR, et al. 2013. BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults. J. Clin. Oncol. 31:e233-36
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. e233-e236
-
-
Chi, A.S.1
Batchelor, T.T.2
Yang, D.3
Dias-Santagata, D.4
Borger, D.R.5
-
50
-
-
80052608062
-
Mutations in CIC and FUBP1 contribute to human oligodendroglioma
-
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, et al. 2011. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science 333:1453-55
-
(2011)
Science
, vol.333
, pp. 1453-1455
-
-
Bettegowda, C.1
Agrawal, N.2
Jiao, Y.3
Sausen, M.4
Wood, L.D.5
-
51
-
-
82755194965
-
Concurrent CICmutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers
-
Yip S, Butterfield YS, Morozova O, Chittaranjan S, BloughMD, et al. 2012. Concurrent CICmutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. J. Pathol. 226:7-16
-
(2012)
J. Pathol.
, vol.226
, pp. 7-16
-
-
Yip, S.1
Butterfield, Y.S.2
Morozova, O.3
Chittaranjan, S.4
Blough, M.D.5
-
52
-
-
84867574186
-
KIAA1549-BRAF fusions and IDH mutations can coexist in diffuse gliomas of adults
-
Badiali M, Gleize V, Paris S, Moi L, Elhouadani S, et al. 2012. KIAA1549-BRAF fusions and IDH mutations can coexist in diffuse gliomas of adults. Brain Pathol. 22:841-47
-
(2012)
Brain Pathol.
, vol.22
, pp. 841-847
-
-
Badiali, M.1
Gleize, V.2
Paris, S.3
Moi, L.4
Elhouadani, S.5
-
53
-
-
84867574820
-
Frequent BRAF gain in lowgrade diffuse gliomas with 1p/19q loss
-
Kim YH, Nonoguchi N, Paulus W, Brokinkel B, Keyvani K, et al. 2012. Frequent BRAF gain in lowgrade diffuse gliomas with 1p/19q loss. Brain Pathol. 22:834-40
-
(2012)
Brain Pathol.
, vol.22
, pp. 834-840
-
-
Kim, Y.H.1
Nonoguchi, N.2
Paulus, W.3
Brokinkel, B.4
Keyvani, K.5
-
54
-
-
84878723078
-
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
-
Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, et al. 2013. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat. Genet. 45:602-12
-
(2013)
Nat. Genet.
, vol.45
, pp. 602-612
-
-
Zhang, J.1
Wu, G.2
Miller, C.P.3
Tatevossian, R.G.4
Dalton, J.D.5
-
55
-
-
84901611641
-
Analysis of KIAA1549-BRAF fusion gene expression and IDH1/IDH2 mutations in low grade pediatric astrocytomas
-
Cruz GR, Dias Oliveira I, Moraes L, Del Giudice Paniago M, de Seixas Alves MT, et al. 2014. Analysis of KIAA1549-BRAF fusion gene expression and IDH1/IDH2 mutations in low grade pediatric astrocytomas. J. Neuro-Oncol. 117:235-42
-
(2014)
J. Neuro-Oncol.
, vol.117
, pp. 235-242
-
-
Cruz, G.R.1
Dias Oliveira, I.2
Moraes, L.3
Del Giudice Paniago, M.4
De Seixas Alves, M.T.5
-
56
-
-
34147205832
-
Molecular pathogenesis of pediatric astrocytic tumors
-
Nakamura M, Shimada K, Ishida E, Higuchi T, Nakase H, et al. 2007. Molecular pathogenesis of pediatric astrocytic tumors. Neuro-Oncology 9:113-23
-
(2007)
Neuro-Oncology
, vol.9
, pp. 113-123
-
-
Nakamura, M.1
Shimada, K.2
Ishida, E.3
Higuchi, T.4
Nakase, H.5
-
57
-
-
49149087048
-
High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas
-
Deshmukh H, Yeh TH, Yu J, Sharma MK, Perry A, et al. 2008. High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas. Oncogene 27:4745-51
-
(2008)
Oncogene
, vol.27
, pp. 4745-4751
-
-
Deshmukh, H.1
Yeh, T.H.2
Yu, J.3
Sharma, M.K.4
Perry, A.5
-
58
-
-
43049133343
-
Comprehensive characterization of genomic aberrations in gangliogliomas by CGH, array-based CGH and interphase FISH
-
Hoischen A, Ehrler M, Fassunke J, Simon M, BaudisM, et al. 2008. Comprehensive characterization of genomic aberrations in gangliogliomas by CGH, array-based CGH and interphase FISH. Brain Pathol. 18:326-37
-
(2008)
Brain Pathol.
, vol.18
, pp. 326-337
-
-
Hoischen, A.1
Ehrler, M.2
Fassunke, J.3
Simon, M.4
Baudis, M.5
-
59
-
-
68749098096
-
Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours
-
Jacob K, Albrecht S, Sollier C, Faury D, Sader E, et al. 2009. Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours. Br. J. Cancer 101:722-33
-
(2009)
Br. J. Cancer
, vol.101
, pp. 722-733
-
-
Jacob, K.1
Albrecht, S.2
Sollier, C.3
Faury, D.4
Sader, E.5
-
60
-
-
43049124130
-
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas
-
Pfister S, Janzarik WG, Remke M, Ernst A,Werft W, et al. 2008. BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. J. Clin. Investig. 118:1739-49
-
(2008)
J. Clin. Investig.
, vol.118
, pp. 1739-1749
-
-
Pfister, S.1
Janzarik, W.G.2
Remke, M.3
Ernst, A.4
Werft, W.5
-
61
-
-
66949147222
-
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene
-
Sievert AJ, Jackson EM, Gai X, Hakonarson H, Judkins AR, et al. 2009. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathol. 19:449-58
-
(2009)
Brain Pathol.
, vol.19
, pp. 449-458
-
-
Sievert, A.J.1
Jackson, E.M.2
Gai, X.3
Hakonarson, H.4
Judkins, A.R.5
-
62
-
-
66849099801
-
Activation of the ERK/MAPK pathway: A signature genetic defect in posterior fossa pilocytic astrocytomas
-
Forshew T, Tatevossian RG, Lawson AR, Ma J, Neale G, et al. 2009. Activation of the ERK/MAPK pathway: A signature genetic defect in posterior fossa pilocytic astrocytomas. J. Pathol. 218:172-81
-
(2009)
J. Pathol.
, vol.218
, pp. 172-181
-
-
Forshew, T.1
Tatevossian, R.G.2
Lawson, A.R.3
Ma, J.4
Neale, G.5
-
63
-
-
84655167688
-
BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants
-
Lin A, Rodriguez FJ, Karajannis MA, Williams SC, Legault G, et al. 2012. BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants. J. Neuropathol. Exp. Neurol. 71:66-72
-
(2012)
J. Neuropathol. Exp. Neurol.
, vol.71
, pp. 66-72
-
-
Lin, A.1
Rodriguez, F.J.2
Karajannis, M.A.3
Williams, S.C.4
Legault, G.5
-
64
-
-
67349219657
-
Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma
-
Jones DT, Kocialkowski S, Liu L, Pearson DM, Ichimura K, Collins VP. 2009. Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. Oncogene 28:2119-23
-
(2009)
Oncogene
, vol.28
, pp. 2119-2123
-
-
Jones, D.T.1
Kocialkowski, S.2
Liu, L.3
Pearson, D.M.4
Ichimura, K.5
Collins, V.P.6
-
65
-
-
79958087774
-
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism ofMAPK pathway activation in pilocytic astrocytoma
-
Cin H, Meyer C, Herr R, Janzarik WG, Lambert S, et al. 2011. Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism ofMAPK pathway activation in pilocytic astrocytoma. Acta Neuropathol. 121:763-74
-
(2011)
Acta Neuropathol.
, vol.121
, pp. 763-774
-
-
Cin, H.1
Meyer, C.2
Herr, R.3
Janzarik, W.G.4
Lambert, S.5
-
66
-
-
84880983541
-
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
-
JonesDT, Hutter B, Jager N, Korshunov A,Kool M, et al. 2013. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat. Genet. 45:927-32
-
(2013)
Nat. Genet.
, vol.45
, pp. 927-932
-
-
Jones, D.T.1
Hutter, B.2
Jager, N.3
Korshunov, A.4
Kool, M.5
-
67
-
-
27144540888
-
RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma
-
Sharma MK, Zehnbauer BA, Watson MA, Gutmann DH. 2005. RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma. Neurology 65:1335-36
-
(2005)
Neurology
, vol.65
, pp. 1335-1336
-
-
Sharma, M.K.1
Zehnbauer, B.A.2
Watson, M.A.3
Gutmann, D.H.4
-
68
-
-
34548726320
-
Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma
-
Janzarik WG, Kratz CP, Loges NT, Olbrich H, Klein C, et al. 2007. Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma. Neuropediatrics 38:61-63
-
(2007)
Neuropediatrics
, vol.38
, pp. 61-63
-
-
Janzarik, W.G.1
Kratz, C.P.2
Loges, N.T.3
Olbrich, H.4
Klein, C.5
-
69
-
-
0026528368
-
Abnormal regulation ofmammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
-
DeClue JE, Papageorge AG, Fletcher JA, Diehl SR, Ratner N, et al. 1992. Abnormal regulation ofmammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis. Cell 69:265-73
-
(1992)
Cell
, vol.69
, pp. 265-273
-
-
DeClue, J.E.1
Papageorge, A.G.2
Fletcher, J.A.3
Diehl, S.R.4
Ratner, N.5
-
70
-
-
78651061485
-
MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas
-
Tatevossian RG, Tang B, Dalton J, Forshew T, Lawson AR, et al. 2010. MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas. Acta Neuropathol. 120:731-43
-
(2010)
Acta Neuropathol.
, vol.120
, pp. 731-743
-
-
Tatevossian, R.G.1
Tang, B.2
Dalton, J.3
Forshew, T.4
Lawson, A.R.5
-
71
-
-
84877866746
-
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1
-
Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, et al. 2013. Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. PNAS 110:8188-93
-
(2013)
PNAS
, vol.110
, pp. 8188-8193
-
-
Ramkissoon, L.A.1
Horowitz, P.M.2
Craig, J.M.3
Ramkissoon, S.H.4
Rich, B.E.5
-
72
-
-
84930188532
-
Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma
-
JonesC, Baker SJ. 2014. Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma. Nat. Rev. Cancer 14:551-61
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 551-561
-
-
Jones, C.1
Baker, S.J.2
-
73
-
-
34547665466
-
Stereotactic biopsy of diffuse pontine lesions in children
-
Roujeau T, Machado G, Garnett MR, Miquel C, Puget S, et al. 2007. Stereotactic biopsy of diffuse pontine lesions in children. J. Neurosurg. 107:1-4
-
(2007)
J. Neurosurg.
, vol.107
, pp. 1-4
-
-
Roujeau, T.1
Machado, G.2
Garnett, M.R.3
Miquel, C.4
Puget, S.5
-
74
-
-
84862777410
-
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
-
Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, et al. 2012. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat. Genet. 44:251-53
-
(2012)
Nat. Genet.
, vol.44
, pp. 251-253
-
-
Wu, G.1
Broniscer, A.2
McEachron, T.A.3
Lu, C.4
Paugh, B.S.5
-
75
-
-
84867606428
-
Hotspot mutations inH3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
-
SturmD,WittH,Hovestadt V, Khuong-Quang DA, JonesDT, et al. 2012. Hotspot mutations inH3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 22:425-37
-
(2012)
Cancer Cell
, vol.22
, pp. 425-437
-
-
Sturm, D.1
Witt, H.2
Hovestadt, V.3
Khuong-Quang, D.A.4
Jones, D.T.5
-
76
-
-
84877621282
-
Histone H3. 3. Mutations drive pediatric glioblastoma through upregulation of MYCN
-
Bjerke L, Mackay A, Nandhabalan M, Burford A, Jury A, et al. 2013. Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN. Cancer Discov. 3:512-19
-
(2013)
Cancer Discov.
, vol.3
, pp. 512-519
-
-
Bjerke, L.1
Mackay, A.2
Nandhabalan, M.3
Burford, A.4
Jury, A.5
-
77
-
-
84899570180
-
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
-
Buczkowicz P, Hoeman C, Rakopoulos P, Pajovic S, Letourneau L, et al. 2014. Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Nat. Genet. 46:451-56
-
(2014)
Nat. Genet.
, vol.46
, pp. 451-456
-
-
Buczkowicz, P.1
Hoeman, C.2
Rakopoulos, P.3
Pajovic, S.4
Letourneau, L.5
-
78
-
-
84899559895
-
Recurrent activatingACVR1 mutations in diffuse intrinsic pontine glioma
-
Taylor KR,Mackay A, Truffaux N, ButterfieldYS, Morozova O, et al. 2014. Recurrent activatingACVR1 mutations in diffuse intrinsic pontine glioma. Nat. Genet. 46:457-61
-
(2014)
Nat. Genet.
, vol.46
, pp. 457-461
-
-
Taylor, K.R.1
Mackay, A.2
Truffaux, N.3
Butterfield, Y.S.4
Morozova, O.5
-
79
-
-
84899539535
-
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma
-
FontebassoAM,Papillon-Cavanagh S, Schwartzentruber J,NikbakhtH,GergesN, et al. 2014. Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. Nat. Genet. 46:462-66
-
(2014)
Nat. Genet.
, vol.46
, pp. 462-466
-
-
Fontebasso, A.M.1
Papillon-Cavanagh, S.2
Schwartzentruber, J.3
Nikbakht, H.4
Gerges, N.5
-
80
-
-
37349067098
-
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
-
Lee J, Son MJ, Woolard K, Donin NM, Li A, et al. 2008. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell 13:69-80
-
(2008)
Cancer Cell
, vol.13
, pp. 69-80
-
-
Lee, J.1
Son, M.J.2
Woolard, K.3
Donin, N.M.4
Li, A.5
-
81
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
-
Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, et al. 2006. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature 444:761-65
-
(2006)
Nature
, vol.444
, pp. 761-765
-
-
Piccirillo, S.G.1
Reynolds, B.A.2
Zanetti, N.3
Lamorte, G.4
Binda, E.5
-
82
-
-
77954596239
-
Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease
-
Paugh BS, Qu C, JonesC, Liu Z, Adamowicz-Brice M, et al. 2010. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J. Clin. Oncol. 28:3061-68
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3061-3068
-
-
Paugh, B.S.1
Qu, C.2
Jones, C.3
Liu, Z.4
Adamowicz-Brice, M.5
-
83
-
-
80053144962
-
A decade of exploring the cancer epigenome-biological and translational implications
-
Baylin SB, Jones PA. 2011. A decade of exploring the cancer epigenome-biological and translational implications. Nat. Rev. Cancer 11:726-34
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
84
-
-
84863621527
-
Cancer epigenetics: From mechanism to therapy
-
Dawson MA, Kouzarides T. 2012. Cancer epigenetics: From mechanism to therapy. Cell 150:12-27
-
(2012)
Cell
, vol.150
, pp. 12-27
-
-
Dawson, M.A.1
Kouzarides, T.2
-
85
-
-
84896739200
-
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
-
Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, et al. 2014. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature 506:445-50
-
(2014)
Nature
, vol.506
, pp. 445-450
-
-
Mack, S.C.1
Witt, H.2
Piro, R.M.3
Gu, L.4
Zuyderduyn, S.5
-
86
-
-
84875537133
-
Epigenetic reprogramming in cancer
-
Suva ML, Riggi N, Bernstein BE. 2013. Epigenetic reprogramming in cancer. Science 339:1567-70
-
(2013)
Science
, vol.339
, pp. 1567-1570
-
-
Suva, M.L.1
Riggi, N.2
Bernstein, B.E.3
-
87
-
-
84894573670
-
Paediatric and adult glioblastoma:Multiform (epi)genomic culprits emerge
-
SturmD, Bender S, Jones DT,Lichter P,Grill J, et al. 2014. Paediatric and adult glioblastoma:Multiform (epi)genomic culprits emerge. Nat. Rev. Cancer 14:92-107
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 92-107
-
-
Sturm, D.1
Bender, S.2
Jones, D.T.3
Lichter, P.4
Grill, J.5
-
88
-
-
84942307003
-
DNA methylation and somatic mutations converge on the cell cycle and define similar evolutionary histories in brain tumors
-
Mazor T, Pankov A, Johnson BE, Hong C, Hamilton EG, et al. 2015. DNA methylation and somatic mutations converge on the cell cycle and define similar evolutionary histories in brain tumors. Cancer Cell 28(3):307-17
-
(2015)
Cancer Cell
, vol.28
, Issue.3
, pp. 307-317
-
-
Mazor, T.1
Pankov, A.2
Johnson, B.E.3
Hong, C.4
Hamilton, E.G.5
-
89
-
-
84944896282
-
EGFR mutation promotes glioblastoma through epigenome and transcription factor network remodeling
-
Liu F, Hon GC, Villa GR, Turner KM, Ikegami S, et al. 2015. EGFR mutation promotes glioblastoma through epigenome and transcription factor network remodeling. Mol. Cell 60(2):307-18
-
(2015)
Mol. Cell
, vol.60
, Issue.2
, pp. 307-318
-
-
Liu, F.1
Hon, G.C.2
Villa, G.R.3
Turner, K.M.4
Ikegami, S.5
-
90
-
-
84921412405
-
Prolonged Ezh2 depletion in glioblastoma causes a robust switch in cell fate resulting in tumor progression
-
de Vries NA, Hulsman D, Akhtar W, de Jong J, Miles DC, et al. 2015. Prolonged Ezh2 depletion in glioblastoma causes a robust switch in cell fate resulting in tumor progression. Cell Rep. 10:383-97
-
(2015)
Cell Rep.
, vol.10
, pp. 383-397
-
-
De Vries, N.A.1
Hulsman, D.2
Akhtar, W.3
De Jong, J.4
Miles, D.C.5
-
91
-
-
84876889621
-
What a difference a hydroxyl makes: Mutant IDH, (R)-2-hydroxyglutarate, and cancer
-
Losman JA, Kaelin WG Jr. 2013. What a difference a hydroxyl makes: Mutant IDH, (R)-2-hydroxyglutarate, and cancer. Genes Dev. 27:836-52
-
(2013)
Genes Dev.
, vol.27
, pp. 836-852
-
-
Losman, J.A.1
Kaelin, W.G.2
-
92
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, et al. 2009. IDH1 and IDH2 mutations in gliomas. N. Engl. J. Med. 360:765-73
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
-
93
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
Turcan S, Rohle D, Goenka A,Walsh LA, Fang F, et al. 2012. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 483:479-83
-
(2012)
Nature
, vol.483
, pp. 479-483
-
-
Turcan, S.1
Rohle, D.2
Goenka, A.3
Walsh, L.A.4
Fang, F.5
-
94
-
-
72049125350
-
Cancer-associated IDH1mutations produce 2-hydroxyglutarate
-
Dang L, WhiteDW, Gross S, Bennett BD, Bittinger MA, et al. 2009. Cancer-associated IDH1mutations produce 2-hydroxyglutarate. Nature 462:739-44
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
-
95
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, et al. 2010. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18:553-67
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
Ward, P.S.4
Patel, J.5
-
96
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, et al. 2010. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468:839-43
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
Pape, U.J.4
Tahiliani, M.5
-
97
-
-
80053215336
-
TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations
-
Kim YH, Pierscianek D, Mittelbronn M, Vital A, Mariani L, et al. 2011. TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations. J. Clin. Pathol. 64:850-52
-
(2011)
J. Clin. Pathol.
, vol.64
, pp. 850-852
-
-
Kim, Y.H.1
Pierscianek, D.2
Mittelbronn, M.3
Vital, A.4
Mariani, L.5
-
98
-
-
84953924597
-
Insulator dysfunction and oncogene activation in IDH mutant gliomas
-
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, et al. 2016. Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature 529:110-14
-
(2016)
Nature
, vol.529
, pp. 110-114
-
-
Flavahan, W.A.1
Drier, Y.2
Liau, B.B.3
Gillespie, S.M.4
Venteicher, A.S.5
-
99
-
-
84904070681
-
MGMTtesting-The challenges for biomarker-based glioma treatment
-
Wick W, WellerM, van den BentM, SansonM,WeilerM, et al. 2014.MGMTtesting-The challenges for biomarker-based glioma treatment. Nat. Rev. Neurol. 10:372-85
-
(2014)
Nat. Rev. Neurol.
, vol.10
, pp. 372-385
-
-
Wick, W.1
Weller, M.2
Van Den Bent, M.3
Sanson, M.4
Weiler, M.5
-
100
-
-
84863091424
-
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: The NOA-08 randomised, phase 3 trial
-
Wick W, Platten M, Meisner C, Felsberg J, Tabatabai G, et al. 2012. Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: The NOA-08 randomised, phase 3 trial. Lancet Oncol. 13:707-15
-
(2012)
Lancet Oncol.
, vol.13
, pp. 707-715
-
-
Wick, W.1
Platten, M.2
Meisner, C.3
Felsberg, J.4
Tabatabai, G.5
-
101
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Res. Netw. 2008. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-68
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
Cancer Genome Atlas Res. Netw1
-
102
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, et al. 2010. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98-110
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
-
103
-
-
84887512911
-
Histone H3. 3 mutations: A variant path to cancer
-
Yuen BT, Knoepfler PS. 2013. Histone H3.3 mutations: A variant path to cancer. Cancer Cell 24:567-74
-
(2013)
Cancer Cell
, vol.24
, pp. 567-574
-
-
Yuen, B.T.1
Knoepfler, P.S.2
-
104
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. 2001. Translating the histone code. Science 293:1074-80
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
105
-
-
84877785024
-
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
-
Lewis PW, Muller MM, Koletsky MS, Cordero F, Lin S, et al. 2013. Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science 340:857-61
-
(2013)
Science
, vol.340
, pp. 857-861
-
-
Lewis, P.W.1
Muller, M.M.2
Koletsky, M.S.3
Cordero, F.4
Lin, S.5
-
106
-
-
84882273357
-
Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas
-
Venneti S, Garimella MT, Sullivan LM, Martinez D, Huse JT, et al. 2013. Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathol. 23:558-64
-
(2013)
Brain Pathol.
, vol.23
, pp. 558-564
-
-
Venneti, S.1
Garimella, M.T.2
Sullivan, L.M.3
Martinez, D.4
Huse, J.T.5
-
107
-
-
84907260816
-
HistoneH3 lysine-to-methioninemutants as a paradigm to study chromatin signaling
-
HerzHM,MorganM,Gao X, Jackson J,RickelsR, et al. 2014. HistoneH3 lysine-to-methioninemutants as a paradigm to study chromatin signaling. Science 345:1065-70
-
(2014)
Science
, vol.345
, pp. 1065-1070
-
-
Herz, H.M.1
Morgan, M.2
Gao, X.3
Jackson, J.4
Rickels, R.5
-
108
-
-
84877299145
-
The histone H3. 3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
-
Chan KM, Fang D, Gan H, Hashizume R, Yu C, et al. 2013. The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression. Genes Dev. 27:985-90
-
(2013)
Genes Dev.
, vol.27
, pp. 985-990
-
-
Chan, K.M.1
Fang, D.2
Gan, H.3
Hashizume, R.4
Yu, C.5
-
109
-
-
73649102464
-
EZH2 is essential for glioblastoma cancer stem cell maintenance
-
Suva ML, Riggi N, JaniszewskaM, Radovanovic I, Provero P, et al. 2009. EZH2 is essential for glioblastoma cancer stem cell maintenance. Cancer Res. 69:9211-18
-
(2009)
Cancer Res.
, vol.69
, pp. 9211-9218
-
-
Suva, M.L.1
Riggi, N.2
Janiszewska, M.3
Radovanovic, I.4
Provero, P.5
-
110
-
-
84919458472
-
Use of human embryonic stem cells to model pediatric gliomas with H3. 3K27M histone mutation
-
Funato K, Major T, Lewis PW, Allis CD, Tabar V. 2014. Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation. Science 346:1529-33
-
(2014)
Science
, vol.346
, pp. 1529-1533
-
-
Funato, K.1
Major, T.2
Lewis, P.W.3
Allis, C.D.4
Tabar, V.5
-
111
-
-
84961291627
-
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma
-
Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, et al. 2014. Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma. Nat. Med. 20:1394-96
-
(2014)
Nat. Med.
, vol.20
, pp. 1394-1396
-
-
Hashizume, R.1
Andor, N.2
Ihara, Y.3
Lerner, R.4
Gan, H.5
-
112
-
-
84930764914
-
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
-
Grasso CS, Tang Y, TruffauxN, BerlowNE, Liu L, et al. 2015. Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nat. Med. 21(6):555-59
-
(2015)
Nat. Med.
, vol.21
, Issue.6
, pp. 555-559
-
-
Grasso, C.S.1
Tang, Y.2
Truffaux, N.3
Berlow, N.E.4
Liu, L.5
-
113
-
-
84858248558
-
Association of age at diagnosis and genetic mutations in patients with neuroblastoma
-
Cheung NK, Zhang J, Lu C, Parker M, Bahrami A, et al. 2012. Association of age at diagnosis and genetic mutations in patients with neuroblastoma. JAMA 307:1062-71
-
(2012)
JAMA
, vol.307
, pp. 1062-1071
-
-
Cheung, N.K.1
Zhang, J.2
Lu, C.3
Parker, M.4
Bahrami, A.5
-
114
-
-
84858796262
-
IDH mutation impairs histone demethylation and results in a block to cell differentiation
-
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, et al. 2012. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 483:474-78
-
(2012)
Nature
, vol.483
, pp. 474-478
-
-
Lu, C.1
Ward, P.S.2
Kapoor, G.S.3
Rohle, D.4
Turcan, S.5
-
115
-
-
84896125494
-
Evolution of the cancer stem cell model
-
Kreso A, Dick JE. 2014. Evolution of the cancer stem cell model. Cell Stem Cell 14:275-91
-
(2014)
Cell Stem Cell
, vol.14
, pp. 275-291
-
-
Kreso, A.1
Dick, J.E.2
-
116
-
-
84884377472
-
Tumour heterogeneity and cancer cell plasticity
-
Meacham CE, Morrison SJ. 2013. Tumour heterogeneity and cancer cell plasticity. Nature 501:328-37
-
(2013)
Nature
, vol.501
, pp. 328-337
-
-
Meacham, C.E.1
Morrison, S.J.2
-
118
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S,Wu Q, McLendon RE, Hao Y, Shi Q, et al. 2006. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444:756-60
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
-
119
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, et al. 2009. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458:780-83
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
Kalisky, T.4
Dorie, M.J.5
-
120
-
-
77950502115
-
A hierarchy of selfrenewing tumor-initiating cell types in glioblastoma
-
Chen R, Nishimura MC, Bumbaca SM, Kharbanda S, Forrest WF, et al. 2010. A hierarchy of selfrenewing tumor-initiating cell types in glioblastoma. Cancer Cell 17:362-75
-
(2010)
Cancer Cell
, vol.17
, pp. 362-375
-
-
Chen, R.1
Nishimura, M.C.2
Bumbaca, S.M.3
Kharbanda, S.4
Forrest, W.F.5
-
121
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, et al. 2008. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat. Genet. 40:499-507
-
(2008)
Nat. Genet.
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
-
122
-
-
84933530651
-
Cancer stem cells in glioblastoma
-
Lathia JD, Mack SC,Mulkearns-Hubert EE, Valentim CL, Rich JN. 2015. Cancer stem cells in glioblastoma. Genes Dev. 29(12):1203-17
-
(2015)
Genes Dev.
, vol.29
, Issue.12
, pp. 1203-1217
-
-
Lathia, J.D.1
Mack, S.C.2
Mulkearns-Hubert, E.E.3
Valentim, C.L.4
Rich, J.N.5
-
123
-
-
78649986150
-
TGF-βreceptor inhibitors target theCD44high/Id1high glioma-initiating cell population in human glioblastoma
-
Anido J, Saez-Borderias A, Gonzalez-Junca A, Rodon L, Folch G, et al. 2010. TGF-βreceptor inhibitors target theCD44high/Id1high glioma-initiating cell population in human glioblastoma. Cancer Cell 18:655-68
-
(2010)
Cancer Cell
, vol.18
, pp. 655-668
-
-
Anido, J.1
Saez-Borderias, A.2
Gonzalez-Junca, A.3
Rodon, L.4
Folch, G.5
-
124
-
-
84865203983
-
A restricted cell population propagates glioblastoma growth after chemotherapy
-
Chen J, Li Y, Yu TS, McKay RM, Burns DK, et al. 2012. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 488:522-26
-
(2012)
Nature
, vol.488
, pp. 522-526
-
-
Chen, J.1
Li, Y.2
Yu, T.S.3
McKay, R.M.4
Burns, D.K.5
-
125
-
-
77956245743
-
Integrin alpha 6 regulates glioblastoma stem cells
-
Lathia JD, Gallagher J, Heddleston JM, Wang J, Eyler CE, et al. 2010. Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell 6:421-32
-
(2010)
Cell Stem Cell
, vol.6
, pp. 421-432
-
-
Lathia, J.D.1
Gallagher, J.2
Heddleston, J.M.3
Wang, J.4
Eyler, C.E.5
-
126
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, et al. 2004. Identification of human brain tumour initiating cells. Nature 432:396-401
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
-
127
-
-
65349115320
-
SSEA-1 is an enrichment marker for tumorinitiating cells in human glioblastoma
-
Son MJ, Woolard K, Nam DH, Lee J, Fine HA. 2009. SSEA-1 is an enrichment marker for tumorinitiating cells in human glioblastoma. Cell Stem Cell 4:440-52
-
(2009)
Cell Stem Cell
, vol.4
, pp. 440-452
-
-
Son, M.J.1
Woolard, K.2
Nam, D.H.3
Lee, J.4
Fine, H.A.5
-
128
-
-
84875340771
-
Widespread resetting of DNA methylation in glioblastoma-initiating cells suppressesmalignant cellular behavior in a lineage-dependent manner
-
Stricker SH, Feber A, Engstrom PG, Caren H, Kurian KM, et al. 2013. Widespread resetting of DNA methylation in glioblastoma-initiating cells suppressesmalignant cellular behavior in a lineage-dependent manner. Genes Dev. 27:654-69
-
(2013)
Genes Dev.
, vol.27
, pp. 654-669
-
-
Stricker, S.H.1
Feber, A.2
Engstrom, P.G.3
Caren, H.4
Kurian, K.M.5
-
129
-
-
84944043452
-
Preferential iron trafficking characterizes glioblastoma stem-like cells
-
Schonberg DL, Miller TE, Wu Q, Flavahan WA, Das NK, et al. 2015. Preferential iron trafficking characterizes glioblastoma stem-like cells. Cancer Cell 28(4):441-55
-
(2015)
Cancer Cell
, vol.28
, Issue.4
, pp. 441-455
-
-
Schonberg, D.L.1
Miller, T.E.2
Wu, Q.3
Flavahan, W.A.4
Das, N.K.5
-
130
-
-
84929704512
-
Differential connexin function enhances self-renewal in glioblastoma
-
Hitomi M, Deleyrolle LP, Mulkearns-Hubert EE, Jarrar A, Li M, et al. 2015. Differential connexin function enhances self-renewal in glioblastoma. Cell Rep. 11(7):1031-42
-
(2015)
Cell Rep.
, vol.11
, Issue.7
, pp. 1031-1042
-
-
Hitomi, M.1
Deleyrolle, L.P.2
Mulkearns-Hubert, E.E.3
Jarrar, A.4
Li, M.5
-
131
-
-
84879983245
-
Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
-
Chaffer CL, Marjanovic ND, Lee T, Bell G, Kleer CG, et al. 2013. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 154:61-74
-
(2013)
Cell
, vol.154
, pp. 61-74
-
-
Chaffer, C.L.1
Marjanovic, N.D.2
Lee, T.3
Bell, G.4
Kleer, C.G.5
-
132
-
-
77952502408
-
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
-
Roesch A, Fukunaga-Kalabis M, Schmidt EC, Zabierowski SE, Brafford PA, et al. 2010. A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. Cell 141:583-94
-
(2010)
Cell
, vol.141
, pp. 583-594
-
-
Roesch, A.1
Fukunaga-Kalabis, M.2
Schmidt, E.C.3
Zabierowski, S.E.4
Brafford, P.A.5
-
133
-
-
84869878282
-
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice
-
Friedmann-Morvinski D, Bushong EA, Ke E, Soda Y, Marumoto T, et al. 2012. Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science 338:1080-84
-
(2012)
Science
, vol.338
, pp. 1080-1084
-
-
Friedmann-Morvinski, D.1
Bushong, E.A.2
Ke, E.3
Soda, Y.4
Marumoto, T.5
-
134
-
-
0032418416
-
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
-
Holland EC, Hively WP, DePinho RA, Varmus HE. 1998. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev. 12:3675-85
-
(1998)
Genes Dev.
, vol.12
, pp. 3675-3685
-
-
Holland, E.C.1
Hively, W.P.2
DePinho, R.A.3
Varmus, H.E.4
-
135
-
-
79960809488
-
Mosaic analysis with double markers reveals tumor cell of origin in glioma
-
Liu C, Sage JC, Miller MR, Verhaak RG, Hippenmeyer S, et al. 2011. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell 146:209-21
-
(2011)
Cell
, vol.146
, pp. 209-221
-
-
Liu, C.1
Sage, J.C.2
Miller, M.R.3
Verhaak, R.G.4
Hippenmeyer, S.5
-
136
-
-
80052468964
-
Stem cell gene expression programs influence clinical outcome in human leukemia
-
Eppert K, Takenaka K, Lechman ER, Waldron L, Nilsson B, et al. 2011. Stem cell gene expression programs influence clinical outcome in human leukemia. Nat. Med. 17:1086-93
-
(2011)
Nat. Med.
, vol.17
, pp. 1086-1093
-
-
Eppert, K.1
Takenaka, K.2
Lechman, E.R.3
Waldron, L.4
Nilsson, B.5
-
137
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida S, Jones S, Bozic I, Antal T, Leary R, et al. 2010. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 467:1114-17
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
Antal, T.4
Leary, R.5
-
138
-
-
84902668801
-
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
-
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, et al. 2014. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science 344:1396-401
-
(2014)
Science
, vol.344
, pp. 1396-1401
-
-
Patel, A.P.1
Tirosh, I.2
Trombetta, J.J.3
Shalek, A.K.4
Gillespie, S.M.5
-
140
-
-
0029059911
-
Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors
-
Bello MJ, Leone PE, Vaquero J, de Campos JM, Kusak ME, et al. 1995. Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors. Int. J. Cancer 64:207-10
-
(1995)
Int. J. Cancer
, vol.64
, pp. 207-210
-
-
Bello, M.J.1
Leone, P.E.2
Vaquero, J.3
De Campos, J.M.4
Kusak, M.E.5
-
141
-
-
0028799791
-
Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma
-
Kraus JA, Koopmann J, Kaskel P,Maintz D, Brandner S, et al. 1995. Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. J. Neuropathol. Exp. Neurol. 54:91-95
-
(1995)
J. Neuropathol. Exp. Neurol.
, vol.54
, pp. 91-95
-
-
Kraus, J.A.1
Koopmann, J.2
Kaskel, P.3
Maintz, D.4
Brandner, S.5
-
142
-
-
77954240113
-
A distinct spectrum of copy number aberrations in pediatric high-grade gliomas
-
Bax DA, Mackay A, Little SE, Carvalho D, Viana-Pereira M, et al. 2010. A distinct spectrum of copy number aberrations in pediatric high-grade gliomas. Clin. Cancer Res. 16:3368-77
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 3368-3377
-
-
Bax, D.A.1
Mackay, A.2
Little, S.E.3
Carvalho, D.4
Viana-Pereira, M.5
-
143
-
-
0027739843
-
Cytogenetic analysis of 109 pediatric central nervous system tumors
-
Neumann E, Kalousek DK, Norman MG, Steinbok P, Cochrane DD, Goddard K. 1993. Cytogenetic analysis of 109 pediatric central nervous system tumors. Cancer Genet. Cytogenet. 71:40-49
-
(1993)
Cancer Genet. Cytogenet.
, vol.71
, pp. 40-49
-
-
Neumann, E.1
Kalousek, D.K.2
Norman, M.G.3
Steinbok, P.4
Cochrane, D.D.5
Goddard, K.6
-
144
-
-
0029150548
-
Nonrandom chromosomal gains in pilocytic astrocytomas of childhood
-
White FV, Anthony DC, Yunis EJ, Tarbell NJ, Scott RM, Schofield DE. 1995. Nonrandom chromosomal gains in pilocytic astrocytomas of childhood. Hum. Pathol. 26:979-86
-
(1995)
Hum. Pathol.
, vol.26
, pp. 979-986
-
-
White, F.V.1
Anthony, D.C.2
Yunis, E.J.3
Tarbell, N.J.4
Scott, R.M.5
Schofield, D.E.6
-
145
-
-
0032527870
-
Are juvenile pilocytic astrocytomas benign tumors? A cytogenetic study in 24 cases
-
Zattara-Cannoni H, Gambarelli D, Lena G, Dufour H, Choux M, et al. 1998. Are juvenile pilocytic astrocytomas benign tumors? A cytogenetic study in 24 cases. Cancer Genet. Cytogenet. 104:157-60
-
(1998)
Cancer Genet. Cytogenet.
, vol.104
, pp. 157-160
-
-
Zattara-Cannoni, H.1
Gambarelli, D.2
Lena, G.3
Dufour, H.4
Choux, M.5
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