The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: A multi-institutional study of 214 astrocytomas

Modern Pathology

Volumn 26, Issue 11, 2013, Pages 1425-1432

  Abedalthagafi, Malak ^a   Phillips, Joanna J ^a   Kim, Grace E ^a   Mueller, Sabine ^a   Haas Kogen, Daphne A ^a   Marshall, Roxanne E ^a   Croul, Sidney E ^b   Santi, Mariarita R ^c   Cheng, Jing ^d   Zhou, Shengmei ^e   Sullivan, Lisa M ^c   Martinez Lage, Maria ^c   Judkins, Alexander R ^e   Perry, Arie ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

alternative lengthening of telomeres; astrocytoma; ATRX; FISH; glioblastoma; IDH1; PDGFRA

Indexed keywords

ALPHA THALASSEMIA MENTAL RETARDATION SYNDROME X LINKED PROTEIN; ISOCITRATE DEHYDROGENASE 1; PEPTIDES AND PROTEINS; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; ASTROCYTOMA; CANCER GRADING; CHILD; CHILDHOOD CANCER; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PANCREATIC NEUROENDOCRINE TUMOR; PHENOTYPE; PILOCYTIC ASTROCYTOMA; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD; TELOMERE HOMEOSTASIS;

ADULT; AGE FACTORS; ASTROCYTOMA; BRAIN NEOPLASMS; CHILD; DNA HELICASES; FEMALE; GENE AMPLIFICATION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; ISOCITRATE DEHYDROGENASE; KAPLAN-MEIER ESTIMATE; MALE; MUTATION; NEOPLASM GRADING; NORTH AMERICA; NUCLEAR PROTEINS; PROPORTIONAL HAZARDS MODELS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RISK FACTORS; TELOMERE; TELOMERE HOMEOSTASIS; TIME FACTORS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 84887123502     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2013.90     Document Type: Article

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