Whole exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma

Oncotarget

Volumn 3, Issue 10, 2012, Pages 1194-1204

  Kannan, Kasthuri ^a   Inagaki, Akiko ^a   Silber, Joachim ^a   Gorovets, Daniel ^a   Zhang, Jianan ^a   Kastenhuber, Edward R ^a   Heguy, Adriana ^a   Petrini, John H ^a   Chan, Timothy A ^a   Huse, Jason T ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Astrocytoma; ATRX; Glioma; IDH; Whole exome sequencing

Indexed keywords

MESSENGER RNA; TUMOR PROTEIN;

ADULT; AGED; ALPHA THALASSEMIA MENTAL RETARDATION SYNDROME X LINKED GENE; ARTICLE; ASTROCYTE; ASTROCYTOMA; CANCER GRADING; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME 19Q; CHROMOSOME 1P; CHROMOSOME DELETION; CLINICAL ARTICLE; EXOME; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENOMIC INSTABILITY; GLIOMA; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN TISSUE; MOLECULAR PATHOLOGY; MUTATIONAL ANALYSIS; NERVE CELL DIFFERENTIATION; NUCLEOTIDE SEQUENCE; OLIGODENDROGLIOMA; SOMATIC MUTATION; SUBVENTRICULAR ZONE; TELOMERE; TRANSCRIPTION REGULATION; TUMOR GENE; TUMOR SUPPRESSOR GENE;

ADULT; AGED; BRAIN NEOPLASMS; DNA HELICASES; DNA, NEOPLASM; EXOME; FEMALE; GLIOMA; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; ISOCITRATE DEHYDROGENASE; MALE; MIDDLE AGED; MUTATION; NEOPLASM GRADING; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROGNOSIS;

EID: 84872788316     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: None     Document Type: Article

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