Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

Science

Volumn 344, Issue 6190, 2014, Pages 1396-1401

  Patel, Anoop P ^a,b,c   Tirosh, Itay ^b   Trombetta, John J ^b   Shalek, Alex K ^b   Gillespie, Shawn M ^a,b,c   Wakimoto, Hiroaki ^a   Cahill, Daniel P ^a   Nahed, Brian V ^a   Curry, William T ^a   Martuza, Robert L ^a   Louis, David N ^a   Rozenblatt Rosen, Orit ^b   Suvà, Mario L ^a,b   Regev, Aviv ^b,c   Bernstein, Bradley E ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTOME; MESSENGER RNA;

GENE EXPRESSION; GENOTYPE; HETEROGENEITY; PHENOTYPE; RNA; SIGNAL;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME 10; CHROMOSOME 7; CHROMOSOME ABERRATION; COPY NUMBER VARIATION; DOWN REGULATION; FLOW CYTOMETRY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNE RESPONSE; OLIGODENDROGLIA; POINT MUTATION; PRIORITY JOURNAL; RNA SEQUENCE; STEM CELL; TUMOR MICROENVIRONMENT; BRAIN NEOPLASMS; CLASSIFICATION; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; GENETICS; PROCEDURES; PROGNOSIS; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS;

BRAIN NEOPLASMS; GENE EXPRESSION PROFILING; GENETIC VARIATION; GLIOBLASTOMA; HUMANS; PROGNOSIS; RNA, MESSENGER; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS;

EID: 84902668801     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1254257     Document Type: Article

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