Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Nature

Volumn 467, Issue 7319, 2010, Pages 1114-1117

  Yachida, Shinichi ^a   Jones, Siân ^b   Bozic, Ivana ^c   Antal, Tibor ^c,d   Leary, Rebecca ^b   Fu, Baojin ^a   Kamiyama, Mihoko ^a   Hruban, Ralph H ^a   Eshleman, James R ^a   Nowak, Martin A ^c   Velculescu, Victor E ^b   Kinzler, Kenneth W ^b   Vogelstein, Bert ^b   Iacobuzio Donahue, Christine A ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c HARVARD UNIVERSITY   (United States)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER; CELL ORGANELLE; CHEMOTHERAPY; DISEASE PREVALENCE; FUNCTIONAL MORPHOLOGY; GENETIC ANALYSIS; GENOME; HETEROGENEITY; MUTATION; QUANTITATIVE ANALYSIS; RADIATION BALANCE;

ARTICLE; CANCER GROWTH; CANCER PREVENTION; CLONAL VARIATION; DISTANT METASTASIS; EARLY DIAGNOSIS; GENE MUTATION; GENETIC CONSERVATION; GENOME; HUMAN; PANCREAS CANCER; PRIMARY TUMOR; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEQUENCE ANALYSIS;

ADENOCARCINOMA; AUTOPSY; CELL LINEAGE; CLONE CELLS; DISEASE PROGRESSION; DNA MUTATIONAL ANALYSIS; EARLY DETECTION OF CANCER; EVOLUTION, MOLECULAR; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; MODELS, BIOLOGICAL; MUTATION; NEOPLASM METASTASIS; PANCREAS; PANCREATIC NEOPLASMS; PERITONEAL NEOPLASMS; TIME FACTORS;

EID: 78049398107     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09515     Document Type: Article

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