Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation

Science

Volumn 346, Issue 6216, 2014, Pages 1529-1533

  Funato, Kosuke ^a   Major, Tamara ^a   Lewis, Peter W ^b   Allis, C David ^c   Tabar, Viviane ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; ANTINEOPLASTIC AGENT; HISTONE; MEN1 PROTEIN, HUMAN; ONCOPROTEIN;

AMINO ACID; BIOASSAY; CELL ORGANELLE; GENOME; MUTATION; PROTEIN;

ANIMAL CELL; ARTICLE; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE LOSS; GENETIC ASSOCIATION; GLIOMA; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NEURAL STEM CELL; NONHUMAN; PROTEIN TARGETING; REGULATOR GENE; TUMOR GROWTH; TUMOR MODEL; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; BRAIN STEM TUMOR; CELL TRANSFORMATION; CHILD; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; PATHOLOGY;

MUS;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN STEM NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; CHILD; DRUG SCREENING ASSAYS, ANTITUMOR; EMBRYONIC STEM CELLS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME-WIDE ASSOCIATION STUDY; GLIOMA; HISTONES; HUMANS; MICE; MODELS, GENETIC; NEURAL STEM CELLS; PROTO-ONCOGENE PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84919458472     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1253799     Document Type: Article

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