Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

Nature Genetics

Volumn 46, Issue 5, 2014, Pages 462-466

  Fontebasso, Adam M ^a   Papillon Cavanagh, Simon ^b   Schwartzentruber, Jeremy ^c   Nikbakht, Hamid ^b   Gerges, Noha ^b   Fiset, Pierre Olivier ^a   Bechet, Denise ^b   Faury, Damien ^b   De Jay, Nicolas ^b   Ramkissoon, Lori A ^d   Corcoran, Aoife ^d   Jones, David T W ^e   Sturm, Dominik ^e   Johann, Pascal ^e   Tomita, Tadanori ^f   Goldman, Stewart ^g   Nagib, Mahmoud ^h   Bendel, Anne ⁱ   Goumnerova, Liliana ^h,j   Bowers, Daniel C ^k   Leonard, Jeffrey R ^l   Rubin, Joshua B ^l   Alden, Tord ^f   Browd, Samuel ^m   Geyer, J Russell ^m   Leary, Sarah ^m   Jallo, George ⁿ   Cohen, Kenneth ^o   Gupta, Nalin ^p   Prados, Michael D ^p   Carret, Anne Sophie ^q   Ellezam, Benjamin ^q   Crevier, Louis ^q   Klekner, Almos ^r   Bognar, Laszlo ^r   Hauser, Peter ^s   Garami, Miklos ^s   Myseros, John ^t   Dong, Zhifeng ^u   Siegel, Peter M ^u   Malkin, Hayley ^d   Ligon, Azra H ^d,h,j,v   Albrecht, Steffen ^a   Pfister, Stefan M ^e   Ligon, Keith L ^d,j,v   Majewski, Jacek ^b   Jabado, Nada ^a,b   Kieran, Mark W ^d,h,j   more..

^a MONTREAL CHILDREN S HOSPITAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^f NORTHWESTERN UNIVERSITY   (United States)

^g NORTHWESTERN UNIVERSITY   (United States)

^h BOSTON CHILDREN S HOSPITAL   (United States)

ⁱ CHILDREN S HOSPITALS AND CLINICS OF MINNESOTA   (United States)

^j HARVARD MEDICAL SCHOOL   (United States)

^k UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^l WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m SEATTLE CHILDREN S HOSPITAL   (United States)

ⁿ JOHNS HOPKINS HOSPITAL   (United States)

^o JOHNS HOPKINS UNIVERSITY   (United States)

^p UNIVERSITY OF CALIFORNIA   (United States)

^q UNIVERSITY OF MONTREAL   (Canada)

^r UNIVERSITY OF DEBRECEN   (Hungary)

^s SEMMELWEIS UNIVERSITY   (Hungary)

^t CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^u MCGILL UNIVERSITY   (Canada)

^v BRIGHAM AND WOMEN S HOSPITAL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A RECEPTOR TYPE 1; BONE MORPHOGENETIC PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; HISTONE H3; INHIBITOR OF DIFFERENTIATION 1; INHIBITOR OF DIFFERENTIATION 2; INHIBITOR OF DIFFERENTIATION 3; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTOMA; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA METHYLATION; DNA RESPONSIVE ELEMENT; GENOMIC INSTABILITY; GERMLINE MUTATION; HIGH GRADE ASTROCYTOMA; HUMAN; HUMAN TISSUE; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SOMATIC MUTATION; ACTIVIN A RECEPTOR TYPE I GENE; ADULT; EARLY RESPONSE GENE; EPIGENETICS; GAIN OF FUNCTION MUTATION; HUMAN CELL; NUCLEOTIDE SEQUENCE; PHENOTYPE; PONS; RECEPTOR GENE; TUMOR CELL; UPREGULATION;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; ASTROCYTOMA; BASE SEQUENCE; BONE MORPHOGENETIC PROTEINS; BRAIN NEOPLASMS; CHILD; DNA COPY NUMBER VARIATIONS; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ANALYSIS, DNA; SMAD PROTEINS;

EID: 84899539535     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2950     Document Type: Article

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