Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene

Brain Pathology

Volumn 19, Issue 3, 2009, Pages 449-458

  Sievert, Angela J ^a,b   Jackson, Eric M ^b   Gai, Xiaowu ^a   Hakonarson, Hakon ^a,b   Judkins, Alexander R ^a   Resnick, Adam C ^a,b   Sutton, Leslie N ^a,b   Storm, Phillip B ^a,b   Shaikh, Tamim H ^a,b   Biegel, Jaclyn A ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

7q34; Astrocytoma; BRAF; Glioma; HIPK2; SNP array

Indexed keywords

B RAF KINASE; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE;

ADOLESCENT; AMINO TERMINAL SEQUENCE; ARTICLE; ASTROCYTOMA; CHILD; CHROMOSOME 7Q; CHROMOSOME DUPLICATION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE MUTATION; GENE SEQUENCE; HIGH DENSITY SINGLE NUCLEOTIDE POLYMORPHISM; HUMAN; HUMAN TISSUE; MALE; PRESCHOOL CHILD; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TANDEM REPEAT; WESTERN BLOTTING;

ADOLESCENT; ADULT; ASTROCYTOMA; BLOTTING, WESTERN; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 7; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; MALE; MAP KINASE SIGNALING SYSTEM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENE PROTEINS, FUSION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS B-RAF; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 66949147222     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2008.00225.x     Document Type: Article

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