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Volumn 123, Issue 2, 2013, Pages 855-865

The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MICRORNA; MICRORNA 99A; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN; SCATTER FACTOR RECEPTOR; TRANSFORMING ACIDIC COILED COIL CONTAINING PROTEIN 3; UNCLASSIFIED DRUG;

EID: 84873347374     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI67144     Document Type: Article
Times cited : (185)

References (41)
  • 1
    • 0022835367 scopus 로고
    • Chromosome translocations and human cancer
    • Croce CM. Chromosome translocations and human cancer. Cancer Res. 1986;46:6019-6023.
    • (1986) Cancer Res. , vol.46 , pp. 6019-6023
    • Croce, C.M.1
  • 2
    • 0026686674 scopus 로고
    • Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours
    • Delattre O, et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature. 1992;359(6391):162-165.
    • (1992) Nature , vol.359 , Issue.6391 , pp. 162-165
    • Delattre, O.1
  • 3
    • 0027933151 scopus 로고
    • Identification of novel genes, SYT and SSX, involved in the t (X;18) (p11.2; q11.2) translocation found in human synovial sarcoma
    • Clark J, et al. Identification of novel genes, SYT and SSX, involved in the t (X;18) (p11.2; q11.2) translocation found in human synovial sarcoma. Nat Genet. 1994;7(4):502-508.
    • (1994) Nat Genet. , vol.7 , Issue.4 , pp. 502-508
    • Clark, J.1
  • 4
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science. 2005;310(5748):644-648.
    • (2005) Science , vol.310 , Issue.5748 , pp. 644-648
    • Tomlins, S.A.1
  • 5
    • 77954526989 scopus 로고    scopus 로고
    • Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
    • Palanisamy N, et al. Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma. Nat Med. 2010;16(7):793-798.
    • (2010) Nat Med. , vol.16 , Issue.7 , pp. 793-798
    • Palanisamy, N.1
  • 6
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature. 2007;448(7153):561-566.
    • (2007) Nature , vol.448 , Issue.7153 , pp. 561-566
    • Soda, M.1
  • 7
    • 36849065315 scopus 로고    scopus 로고
    • Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    • Rikova K, et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell. 2007;131(6):1190-1203.
    • (2007) Cell , vol.131 , Issue.6 , pp. 1190-1203
    • Rikova, K.1
  • 8
    • 19044391610 scopus 로고    scopus 로고
    • Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma
    • Tognon C, et al. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell. 2002;2(5):367-376.
    • (2002) Cancer Cell , vol.2 , Issue.5 , pp. 367-376
    • Tognon, C.1
  • 9
    • 80053330506 scopus 로고    scopus 로고
    • ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma
    • Salzman J, et al. ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma. PLoS Biol. 2011;9(9):e1001156.
    • (2011) PLoS Biol. , vol.9 , Issue.9
    • Salzman, J.1
  • 10
    • 0021802841 scopus 로고
    • Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
    • Shtivelman E, Lifshitz B, Gale RP, Canaani E. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature. 1985;315(6020):550-554.
    • (1985) Nature , vol.315 , Issue.6020 , pp. 550-554
    • Shtivelman, E.1    Lifshitz, B.2    Gale, R.P.3    Canaani, E.4
  • 11
    • 56449115626 scopus 로고    scopus 로고
    • C-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster
    • Chung EY, et al. c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster. Cancer Biol Ther. 2008;7(11):1758-1764.
    • (2008) Cancer Biol Ther. , vol.7 , Issue.11 , pp. 1758-1764
    • Chung, E.Y.1
  • 12
    • 60249101120 scopus 로고    scopus 로고
    • The c-myb proto-oncogene and microRNA-15a comprise an active autoregulatory feedback loop in human hematopoietic cells
    • Zhao H, Kalota A, Jin S, Gewirtz AM. The c-myb proto-oncogene and microRNA-15a comprise an active autoregulatory feedback loop in human hematopoietic cells. Blood. 2009;113(3):505-516.
    • (2009) Blood , vol.113 , Issue.3 , pp. 505-516
    • Zhao, H.1    Kalota, A.2    Jin, S.3    Gewirtz, A.M.4
  • 13
    • 73249115584 scopus 로고    scopus 로고
    • Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
    • Persson M, Andrén Y, Mark J, Horlings HM, Persson F, Stenman G. Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. Proc Natl Acad Sci U S A. 2009;106(44):18740-18744.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.44 , pp. 18740-18744
    • Persson, M.1    Andrén, Y.2    Mark, J.3    Horlings, H.M.4    Persson, F.5    Stenman, G.6
  • 14
    • 33845444046 scopus 로고    scopus 로고
    • Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
    • Druker BJ, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med. 2006;355(23):2408-2417.
    • (2006) N Engl J Med. , vol.355 , Issue.23 , pp. 2408-2417
    • Druker, B.J.1
  • 15
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
    • Shaw AT, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol. 2011;12(11):1004-1012.
    • (2011) Lancet Oncol. , vol.12 , Issue.11 , pp. 1004-1012
    • Shaw, A.T.1
  • 16
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study:5-year analysis of the EORTC-NCIC trial
    • Stupp R, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study:5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009;10(5):459-466.
    • (2009) Lancet Oncol. , vol.10 , Issue.5 , pp. 459-466
    • Stupp, R.1
  • 17
    • 54549108740 scopus 로고    scopus 로고
    • The Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • The Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455(7216):1061-1068.
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1061-1068
  • 18
    • 80053076113 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor alpha in glioma: A bad seed
    • Liu KW, Hu B, Cheng SY. Platelet-derived growth factor receptor alpha in glioma: a bad seed. Chin J Cancer. 2011;30(9):590-602.
    • (2011) Chin J Cancer , vol.30 , Issue.9 , pp. 590-602
    • Liu, K.W.1    Hu, B.2    Cheng, S.Y.3
  • 19
    • 55349107544 scopus 로고    scopus 로고
    • Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
    • Jones D, et al. Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res. 2008;68(21):8673-8677.
    • (2008) Cancer Res. , vol.68 , Issue.21 , pp. 8673-8677
    • Jones, D.1
  • 20
    • 77952032145 scopus 로고    scopus 로고
    • Integrated genomic profiling identifies candidate genes implicated in gliomagenesis and a novel LEO1-SLC12A1 fusion gene
    • Bralten LB, et al. Integrated genomic profiling identifies candidate genes implicated in gliomagenesis and a novel LEO1-SLC12A1 fusion gene. Genes Chromosomes Cancer. 2010;49(6):509-517.
    • (2010) Genes Chromosomes Cancer , vol.49 , Issue.6 , pp. 509-517
    • Bralten, L.B.1
  • 21
    • 84865805666 scopus 로고    scopus 로고
    • Transforming fusions of FGFR and TACC genes in human glioblastoma
    • Singh D, et al. Transforming fusions of FGFR and TACC genes in human glioblastoma. Science. 2012;337(6099):1231-1235.
    • (2012) Science , vol.337 , Issue.6099 , pp. 1231-1235
    • Singh, D.1
  • 22
    • 0032841519 scopus 로고    scopus 로고
    • Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas
    • Cappellen D, et al. Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nat Genet. 1999;23(1):18-20.
    • (1999) Nat Genet. , vol.23 , Issue.1 , pp. 18-20
    • Cappellen, D.1
  • 23
    • 0034677206 scopus 로고    scopus 로고
    • D-TACC: A novel centrosomal protein required for normal spindle function in the early Drosophila embryo
    • Gergely F, Kidd D, Jeffers K, Wakefield JG, Raff JW. D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo. EMBO J. 2000;19(2):241-252.
    • (2000) EMBO J. , vol.19 , Issue.2 , pp. 241-252
    • Gergely, F.1    Kidd, D.2    Jeffers, K.3    Wakefield, J.G.4    Raff, J.W.5
  • 24
    • 0033152107 scopus 로고    scopus 로고
    • The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines
    • Still IH, Vince P, Cowell JK. The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines. Genomics. 1999;58(2):165-170.
    • (1999) Genomics , vol.58 , Issue.2 , pp. 165-170
    • Still, I.H.1    Vince, P.2    Cowell, J.K.3
  • 25
    • 80053578487 scopus 로고    scopus 로고
    • The physical basis of FGFR3 response to fgf1 and fgf2
    • Chen F, Hristova K. The physical basis of FGFR3 response to fgf1 and fgf2. Biochemistry. 2011;50(40):8576-8582.
    • (2011) Biochemistry , vol.50 , Issue.40 , pp. 8576-8582
    • Chen, F.1    Hristova, K.2
  • 26
    • 30044431810 scopus 로고    scopus 로고
    • Transcription-mediated gene fusion in the human genome
    • Akiva P, et al. Transcription-mediated gene fusion in the human genome. Genome Res. 2006;16(1):30-36.
    • (2006) Genome Res. , vol.16 , Issue.1 , pp. 30-36
    • Akiva, P.1
  • 27
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120(1):15-20.
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 28
    • 80051791926 scopus 로고    scopus 로고
    • MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways
    • Oneyama C, et al. MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways. Oncogene. 2011;30(32):3489-3501.
    • (2011) Oncogene , vol.30 , Issue.32 , pp. 3489-3501
    • Oneyama, C.1
  • 29
    • 78650716349 scopus 로고    scopus 로고
    • Differential miRNA expression profiles in bladder urothelial carcinomas
    • Song T, et al. Differential miRNA expression profiles in bladder urothelial carcinomas. Asian Pac J Cancer Prev. 2010;11(4):905-911.
    • (2010) Asian Pac J Cancer Prev. , vol.11 , Issue.4 , pp. 905-911
    • Song, T.1
  • 30
    • 84855382989 scopus 로고    scopus 로고
    • MicroRNA-99b acts as a tumor suppressor in non-small cell lung cancer by directly targeting fibroblast growth factor receptor 3
    • Kang J, et al. microRNA-99b acts as a tumor suppressor in non-small cell lung cancer by directly targeting fibroblast growth factor receptor 3. Exp Ther Med. 2012;3(1):149-153.
    • (2012) Exp Ther Med. , vol.3 , Issue.1 , pp. 149-153
    • Kang, J.1
  • 31
    • 22044440001 scopus 로고    scopus 로고
    • Immunohistochemistry accurately predicts FGFR3 aberrant expression and t (4;14) in multiple myeloma
    • Chang H, Stewart AK, Qi XY, Li ZH, Yi QL, Trudel S. Immunohistochemistry accurately predicts FGFR3 aberrant expression and t (4;14) in multiple myeloma. Blood. 2005;106(1):353-355.
    • (2005) Blood , vol.106 , Issue.1 , pp. 353-355
    • Chang, H.1    Stewart, A.K.2    Qi, X.Y.3    Li, Z.H.4    Yi, Q.L.5    Trudel, S.6
  • 32
    • 19944426549 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth
    • Gómez-Román JJ, et al. Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth. Clin Cancer Res. 2005;11(2 pt 1):459-465.
    • (2005) Clin Cancer Res. , vol.11 , Issue.2 PART 1 , pp. 459-465
    • Gómez-Román, J.J.1
  • 33
    • 0038137601 scopus 로고    scopus 로고
    • Gene expression profiles of human breast cancer progression
    • Ma XJ, et al. Gene expression profiles of human breast cancer progression. Proc Natl Acad Sci U S A. 2003;100(10):5974-5979.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.10 , pp. 5974-5979
    • Ma, X.J.1
  • 34
    • 33747477095 scopus 로고    scopus 로고
    • Expression of transforming acidic coiled-coil containing protein 3 is a novel independent prognostic marker in non-small cell lung cancer
    • Jung CK, Jung JH, Park GS, Lee A, Kang CS, Lee KY. Expression of transforming acidic coiled-coil containing protein 3 is a novel independent prognostic marker in non-small cell lung cancer. Pathol Int. 2006;56(9):503-509.
    • (2006) Pathol Int. , vol.56 , Issue.9 , pp. 503-509
    • Jung, C.K.1    Jung, J.H.2    Park, G.S.3    Lee, A.4    Kang, C.S.5    Lee, K.Y.6
  • 35
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009;10(3):R25.
    • (2009) Genome Biol. , vol.10 , Issue.3
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 36
    • 84872906748 scopus 로고    scopus 로고
    • Transcriptome and small RNA deep sequencing reveals deregulation of miRNA biogenesis in human glioma
    • published online ahead of print September 24, doi:10.1002/path.4109
    • Moore L, et al. Transcriptome and small RNA deep sequencing reveals deregulation of miRNA biogenesis in human glioma [published online ahead of print September 24, 2012]. J Pathol. doi:10.1002/path.4109.
    • (2012) J Pathol.
    • Moore, L.1
  • 37
    • 3543105225 scopus 로고    scopus 로고
    • Circular binary segmentation for the analysis of array-based DNA copy number data
    • Olshen AB, Venkatraman ES, Lucito R, Wigler M. Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics. 2004;5(4):557-572.
    • (2004) Biostatistics , vol.5 , Issue.4 , pp. 557-572
    • Olshen, A.B.1    Venkatraman, E.S.2    Lucito, R.3    Wigler, M.4
  • 38
    • 0043092322 scopus 로고    scopus 로고
    • Insulin-like Growth Factor Binding Protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes
    • Wang H, et al. Insulin-like Growth Factor Binding Protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes. Cancer Res. 2003;63(15):4315-4321.
    • (2003) Cancer Res. , vol.63 , Issue.15 , pp. 4315-4321
    • Wang, H.1
  • 39
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry RA, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003;4(2):249-264.
    • (2003) Biostatistics , vol.4 , Issue.2 , pp. 249-264
    • Irizarry, R.A.1
  • 40
    • 0033960389 scopus 로고    scopus 로고
    • An implantable guide-screw system for brain tumor studies in small animals
    • Lal S, Lacroix M, Tofilon P, Fuller GN, Sawaya R, Lang FF. An implantable guide-screw system for brain tumor studies in small animals. J Neurosurg. 2000;92(2):326-333.
    • (2000) J Neurosurg. , vol.92 , Issue.2 , pp. 326-333
    • Lal, S.1    Lacroix, M.2    Tofilon, P.3    Fuller, G.N.4    Sawaya, R.5    Lang, F.F.6
  • 41
    • 20244374417 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas
    • Nakamizo A, et al. Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res. 2005;65(8):3307-3318.
    • (2005) Cancer Res. , vol.65 , Issue.8 , pp. 3307-3318
    • Nakamizo, A.1


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