-
1
-
-
69249124251
-
Male-biased effects of gonadotropin-releasing hormone neuron- specific deletion of the phosphoinositide 3-kinase regulatory subunit p85α on the reproductive axis
-
Acosta-Martinez M, Luo J, Elias C, Wolfe A, Levine JE. 2009 Male-biased effects of gonadotropin-releasing hormone neuron- specific deletion of the phosphoinositide 3-kinase regulatory subunit p85α on the reproductive axis. Endocrinology 150: 4203–4212
-
(2009)
Endocrinology
, vol.150
, pp. 4203-4212
-
-
Acosta-Martinez, M.1
Luo, J.2
Elias, C.3
Wolfe, A.4
Levine, J.E.5
-
2
-
-
0033622470
-
Essential role of p38α MAP kinase in placental but not embryonic cardiovascular development
-
Adams RH, Porras A, Alonso G, Jones M, Vintersten K, Panelli S, Valladares A, Perez L, Klein R, Nebreda AR. 2000 Essential role of p38α MAP kinase in placental but not embryonic cardiovascular development. Mol Cell 6: 109–116
-
(2000)
Mol Cell
, vol.6
, pp. 109-116
-
-
Adams, R.H.1
Porras, A.2
Alonso, G.3
Jones, M.4
Vintersten, K.5
Panelli, S.6
Valladares, A.7
Perez, L.8
Klein, R.9
Nebreda, A.R.10
-
3
-
-
70350001098
-
Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function
-
Ahmed Z, George R, Lin CC, Suen KM, Levitt JA, Suhling K, Ladbury JE. 2010 Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function. Cell Signal 22: 23–33
-
(2010)
Cell Signal
, vol.22
, pp. 23-33
-
-
Ahmed, Z.1
George, R.2
Lin, C.C.3
Suen, K.M.4
Levitt, J.A.5
Suhling, K.6
Ladbury, J.E.7
-
4
-
-
84874368710
-
Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity
-
Ahmed Z, Lin CC, Suen KM, Melo FA, Levitt JA, Suhling K, Ladbury JE. 2013 Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity. J Cell Biol 200: 493–504
-
(2013)
J Cell Biol
, vol.200
, pp. 493-504
-
-
Ahmed, Z.1
Lin, C.C.2
Suen, K.M.3
Melo, F.A.4
Levitt, J.A.5
Suhling, K.6
Ladbury, J.E.7
-
5
-
-
84949480975
-
Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development
-
Al Alam D, El Agha E, Sakurai R, Kheirollahi V, Moiseenko A, Danopoulos S, Shrestha A, Schmoldt C, Quantius J, Herold S, et al. 2015 Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development. Development 142: 4139–4150
-
(2015)
Development
, vol.142
, pp. 4139-4150
-
-
Al Alam, D.1
El Agha, E.2
Sakurai, R.3
Kheirollahi, V.4
Moiseenko, A.5
Danopoulos, S.6
Shrestha, A.7
Schmoldt, C.8
Quantius, J.9
Herold, S.10
-
6
-
-
0242677706
-
Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly
-
Allen BL, Rapraeger AC. 2003 Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly. J Cell Biol 163: 637–648
-
(2003)
J Cell Biol
, vol.163
, pp. 637-648
-
-
Allen, B.L.1
Rapraeger, A.C.2
-
7
-
-
0032574824
-
Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development
-
Arman E, Haffner-Krausz R, Chen Y, Heath JK, Lonai P. 1998 Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc Natl Acad Sci 95: 5082–5087
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 5082-5087
-
-
Arman, E.1
Haffner-Krausz, R.2
Chen, Y.3
Heath, J.K.4
Lonai, P.5
-
8
-
-
84862146459
-
FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man
-
Barak H, Huh SH, Chen S, Jeanpierre C, Martinovic J, Parisot M, Bole-Feysot C, Nitschke P, Salomon R, Antignac C, et al. 2012 FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man. Dev Cell 22: 1191–1207
-
(2012)
Dev Cell
, vol.22
, pp. 1191-1207
-
-
Barak, H.1
Huh, S.H.2
Chen, S.3
Jeanpierre, C.4
Martinovic, J.5
Parisot, M.6
Bole-Feysot, C.7
Nitschke, P.8
Salomon, R.9
Antignac, C.10
-
9
-
-
80052289843
-
Role of fibroblast growth factor receptor signaling in kidney development
-
Bates CM. 2011 Role of fibroblast growth factor receptor signaling in kidney development. Pediatr Nephrol 26: 1373–1379
-
(2011)
Pediatr Nephrol
, vol.26
, pp. 1373-1379
-
-
Bates, C.M.1
-
10
-
-
0014499309
-
Cutis gyratum, acanthosis nigricans and other congenital anomalies. A new syndrome
-
Beare JM, Dodge JA, Nevin NC. 1969 Cutis gyratum, acanthosis nigricans and other congenital anomalies. A new syndrome. Br J Dermatol 81: 241–247
-
(1969)
Br J Dermatol
, vol.81
, pp. 241-247
-
-
Beare, J.M.1
Dodge, J.A.2
Nevin, N.C.3
-
11
-
-
84942063845
-
The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development
-
Bebee TW, Park JW, Sheridan KI, Warzecha CC, Cieply BW, Rohacek AM, Xing Y, Carstens RP. 2015 The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife 4: e08954
-
(2015)
Elife
, vol.4
-
-
Bebee, T.W.1
Park, J.W.2
Sheridan, K.I.3
Warzecha, C.C.4
Cieply, B.W.5
Rohacek, A.M.6
Xing, Y.7
Carstens, R.P.8
-
12
-
-
0025913477
-
Ligand-induced transphosphorylation between different FGF receptors
-
Bellot F, Crumley G, Kaplow JM, Schlessinger J, Jaye M, Dionne CA. 1991 Ligand-induced transphosphorylation between different FGF receptors. EMBO J 10: 2849–2854
-
(1991)
EMBO J
, vol.10
, pp. 2849-2854
-
-
Bellot, F.1
Crumley, G.2
Kaplow, J.M.3
Schlessinger, J.4
Jaye, M.5
Dionne, C.A.6
-
13
-
-
0031457616
-
Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung
-
Bellusci S, Grindley J, Emoto H, Itoh N, Hogan BL. 1997 Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124: 4867–4878
-
(1997)
Development
, vol.124
, pp. 4867-4878
-
-
Bellusci, S.1
Grindley, J.2
Emoto, H.3
Itoh, N.4
Hogan, B.L.5
-
14
-
-
77954516397
-
A random cell motility gradient downstream of FGF controls elongation of an amniote embryo
-
Benazeraf B, Francois P, Baker RE, Denans N, Little CD, Pourquie O. 2010 A random cell motility gradient downstream of FGF controls elongation of an amniote embryo. Nature 466: 248–252
-
(2010)
Nature
, vol.466
, pp. 248-252
-
-
Benazeraf, B.1
Francois, P.2
Baker, R.E.3
Denans, N.4
Little, C.D.5
Pourquie, O.6
-
15
-
-
0029134104
-
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud
-
Bladt F, Riethmacher D, Isenmann S, Aguzzi A, Birchmeier C. 1995 Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature 376: 768–771
-
(1995)
Nature
, vol.376
, pp. 768-771
-
-
Bladt, F.1
Riethmacher, D.2
Isenmann, S.3
Aguzzi, A.4
Birchmeier, C.5
-
16
-
-
33846901154
-
Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain
-
Blak AA, Naserke T, Saarimaki-Vire J, Peltopuro P, Giraldo- Velasquez M, Vogt Weisenhorn DM, Prakash N, Sendtner M, Partanen J, WurstW. 2007 Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol 303: 231–243
-
(2007)
Dev Biol
, vol.303
, pp. 231-243
-
-
Blak, A.A.1
Naserke, T.2
Saarimaki-Vire, J.3
Peltopuro, P.4
Giraldo- Velasquez, M.5
Vogt Weisenhorn, D.M.6
Prakash, N.7
Sendtner, M.8
Partanen, J.9
-
17
-
-
15044358690
-
Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangement
-
Brachmann SM, Yballe CM, Innocenti M, Deane JA, Fruman DA, Thomas SM, Cantley LC. 2005 Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangement. Mol Cell Biol 25: 2593–2606
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2593-2606
-
-
Brachmann, S.M.1
Yballe, C.M.2
Innocenti, M.3
Deane, J.A.4
Fruman, D.A.5
Thomas, S.M.6
Cantley, L.C.7
-
18
-
-
84965089687
-
Fgfr1 regulates development through the combinatorial use of signaling proteins
-
Brewer JR, Molotkov A, Mazot P, Hoch RV, Soriano P. 2015 Fgfr1 regulates development through the combinatorial use of signaling proteins. Genes Dev 29: 1863–1874
-
(2015)
Genes Dev
, vol.29
, pp. 1863-1874
-
-
Brewer, J.R.1
Molotkov, A.2
Mazot, P.3
Hoch, R.V.4
Soriano, P.5
-
19
-
-
78049237406
-
Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation
-
Browaeys-Poly E, Blanquart C, Perdereau D, Antoine AF, Goenaga D, Luzy JP, Chen H, Garbay C, Issad T, Cailliau K, et al. 2010 Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation. FEBS Lett 584: 4383–4388
-
(2010)
FEBS Lett
, vol.584
, pp. 4383-4388
-
-
Browaeys-Poly, E.1
Blanquart, C.2
Perdereau, D.3
Antoine, A.F.4
Goenaga, D.5
Luzy, J.P.6
Chen, H.7
Garbay, C.8
Issad, T.9
Cailliau, K.10
-
20
-
-
84878869699
-
Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma
-
Cai Z, Tao C, Li H, Ladher R, Gotoh N, Feng GS, Wang F, Zhang X. 2013 Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma. Development 140: 2711–2723
-
(2013)
Development
, vol.140
, pp. 2711-2723
-
-
Cai, Z.1
Tao, C.2
Li, H.3
Ladher, R.4
Gotoh, N.5
Feng, G.S.6
Wang, F.7
Zhang, X.8
-
21
-
-
80051553050
-
A missense mutation in Fgfr1 causes ear and skull defects in hush puppy mice
-
Calvert JA, Dedos SG, Hawker K, Fleming M, Lewis MA, Steel KP. 2011 A missense mutation in Fgfr1 causes ear and skull defects in hush puppy mice. Mamm Genome 22: 290–305
-
(2011)
Mamm Genome
, vol.22
, pp. 290-305
-
-
Calvert, J.A.1
Dedos, S.G.2
Hawker, K.3
Fleming, M.4
Lewis, M.A.5
Steel, K.P.6
-
22
-
-
84925456768
-
Careless talk costs lives: Fibroblast growth factor receptor signalling and the consequences of pathway malfunction
-
Carter EP, Fearon AE, Grose RP. 2015 Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction. Trends Cell Biol 25: 221–233
-
(2015)
Trends Cell Biol
, vol.25
, pp. 221-233
-
-
Carter, E.P.1
Fearon, A.E.2
Grose, R.P.3
-
23
-
-
11144271353
-
Tyrosine 769 of the keratinocyte growth factor receptor is required for receptor signaling but not endocytosis
-
Ceridono M, Belleudi F, Ceccarelli S, Torrisi MR. 2005 Tyrosine 769 of the keratinocyte growth factor receptor is required for receptor signaling but not endocytosis. Biochem Biophys Res Commun 327: 523–532
-
(2005)
Biochem Biophys Res Commun
, vol.327
, pp. 523-532
-
-
Ceridono, M.1
Belleudi, F.2
Ceccarelli, S.3
Torrisi, M.R.4
-
24
-
-
84957852055
-
FGFR and PTEN signaling interact during lens development to regulate cell survival
-
Chaffee BR, Hoang TV, Leonard MR, Bruney DG, Wagner BD, Dowd JR, Leone G, Ostrowski MC, Robinson ML. 2016 FGFR and PTEN signaling interact during lens development to regulate cell survival. Dev Biol 410: 150–163
-
(2016)
Dev Biol
, vol.410
, pp. 150-163
-
-
Chaffee, B.R.1
Hoang, T.V.2
Leonard, M.R.3
Bruney, D.G.4
Wagner, B.D.5
Dowd, J.R.6
Leone, G.7
Ostrowski, M.C.8
Robinson, M.L.9
-
25
-
-
33646527782
-
Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2–MAPK pathway
-
Chazaud C, Yamanaka Y, Pawson T, Rossant J. 2006 Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2–MAPK pathway. Dev Cell 10: 615–624
-
(2006)
Dev Cell
, vol.10
, pp. 615-624
-
-
Chazaud, C.1
Yamanaka, Y.2
Pawson, T.3
Rossant, J.4
-
26
-
-
0028239789
-
Fibroblast growth factor receptor (FGFR) 3 Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1
-
Chellaiah AT, McEwen DG, Werner S, Xu J, Ornitz DM. 1994 Fibroblast growth factor receptor (FGFR) 3 Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1. J Biol Chem 269: 11620–11627
-
(1994)
J Biol Chem
, vol.269
, pp. 11620-11627
-
-
Chellaiah, A.T.1
McEwen, D.G.2
Werner, S.3
Xu, J.4
Ornitz, D.M.5
-
27
-
-
0033456159
-
Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis
-
Chen L, Adar R, Yang X, Monsonego EO, Li C, Hauschka PV, Yayon A, Deng CX. 1999 Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis. J Clin Invest 104: 1517–1525
-
(1999)
J Clin Invest
, vol.104
, pp. 1517-1525
-
-
Chen, L.1
Adar, R.2
Yang, X.3
Monsonego, E.O.4
Li, C.5
Hauschka, P.V.6
Yayon, A.7
Deng, C.X.8
-
28
-
-
84900305191
-
A Ser252Trp mutation in fibroblast growth factor receptor 2 (FGFR2) mimicking human Apert syndrome reveals an essential role for FGF signaling in the regulation of endochondral bone formation
-
Chen P, Zhang L, Weng T, Zhang S, Sun S, Chang M, Li Y, Zhang B, Zhang L. 2014a. A Ser252Trp mutation in fibroblast growth factor receptor 2 (FGFR2) mimicking human Apert syndrome reveals an essential role for FGF signaling in the regulation of endochondral bone formation. PLoS One 9: e87311
-
(2014)
Plos One
, vol.9
-
-
Chen, P.1
Zhang, L.2
Weng, T.3
Zhang, S.4
Sun, S.5
Chang, M.6
Li, Y.7
Zhang, B.8
Zhang, L.9
-
29
-
-
84898827703
-
The docking protein FRS2α is a critical regulator of VEGF receptors signaling
-
Chen PY, Qin L, Zhuang ZW, Tellides G, Lax I, Schlessinger J, Simons M. 2014b. The docking protein FRS2α is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci 111: 5514–5519
-
(2014)
Proc Natl Acad Sci
, vol.111
, pp. 5514-5519
-
-
Chen, P.Y.1
Qin, L.2
Zhuang, Z.W.3
Tellides, G.4
Lax, I.5
Schlessinger, J.6
Simons, M.7
-
30
-
-
0032948651
-
Expression of the T-box gene Eomesodermin during early mouse development
-
Ciruna BG, Rossant J. 1999 Expression of the T-box gene Eomesodermin during early mouse development. Mech Dev 81: 199–203
-
(1999)
Mech Dev
, vol.81
, pp. 199-203
-
-
Ciruna, B.G.1
Rossant, J.2
-
31
-
-
0035408007
-
FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak
-
Ciruna B, Rossant J. 2001 FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev Cell 1: 37–49
-
(2001)
Dev Cell
, vol.1
, pp. 37-49
-
-
Ciruna, B.1
Rossant, J.2
-
32
-
-
0030743776
-
Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: A role for FGFR1 in morphogenetic movement through the primitive streak
-
Ciruna BG, Schwartz L, Harpal K, Yamaguchi TP, Rossant J. 1997 Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak. Development 124: 2829–2841
-
(1997)
Development
, vol.124
, pp. 2829-2841
-
-
Ciruna, B.G.1
Schwartz, L.2
Harpal, K.3
Yamaguchi, T.P.4
Rossant, J.5
-
33
-
-
0029928791
-
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
-
Colvin JS, Bohne BA, Harding GW, McEwen DG, Ornitz DM. 1996 Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat Genet 12: 390–397
-
(1996)
Nat Genet
, vol.12
, pp. 390-397
-
-
Colvin, J.S.1
Bohne, B.A.2
Harding, G.W.3
McEwen, D.G.4
Ornitz, D.M.5
-
34
-
-
10744225161
-
Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice
-
Cooney GJ, Lyons RJ, Crew AJ, Jensen TE, Molero JC, Mitchell CJ, Biden TJ, Ormandy CJ, James DE, Daly RJ. 2004 Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice. EMBO J 23: 582–593
-
(2004)
EMBO J
, vol.23
, pp. 582-593
-
-
Cooney, G.J.1
Lyons, R.J.2
Crew, A.J.3
Jensen, T.E.4
Molero, J.C.5
Mitchell, C.J.6
Biden, T.J.7
Ormandy, C.J.8
James, D.E.9
Daly, R.J.10
-
35
-
-
0142074405
-
Spatial and temporal patterns of ERK signaling during mouse embryogenesis
-
Corson LB, Yamanaka Y, Lai KM, Rossant J. 2003 Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development 130: 4527–4537
-
(2003)
Development
, vol.130
, pp. 4527-4537
-
-
Corson, L.B.1
Yamanaka, Y.2
Lai, K.M.3
Rossant, J.4
-
36
-
-
0036679107
-
The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells
-
Cross MJ, Lu L, Magnusson P, Nyqvist D, Holmqvist K, Welsh M, Claesson-Welsh L. 2002 The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells. Mol Biol Cell 13: 2881–2893
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2881-2893
-
-
Cross, M.J.1
Lu, L.2
Magnusson, P.3
Nyqvist, D.4
Holmqvist, K.5
Welsh, M.6
Claesson-Welsh, L.7
-
37
-
-
0028959288
-
The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
-
Crossley PH, Martin GR. 1995 The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121: 439–451
-
(1995)
Development
, vol.121
, pp. 439-451
-
-
Crossley, P.H.1
Martin, G.R.2
-
38
-
-
77952037166
-
Differential phosphoproteomics of fibroblast growth factor signaling: Identification of Src family kinase-mediated phosphorylation events
-
Cunningham DL, Sweet SM, Cooper HJ, Heath JK. 2010 Differential phosphoproteomics of fibroblast growth factor signaling: identification of Src family kinase-mediated phosphorylation events. J Proteome Res 9: 2317–2328
-
(2010)
J Proteome Res
, vol.9
, pp. 2317-2328
-
-
Cunningham, D.L.1
Sweet, S.M.2
Cooper, H.J.3
Heath, J.K.4
-
39
-
-
84929208109
-
Distinct sets of FGF receptors sculpt excitatory and inhibitory synaptogenesis
-
Dabrowski A, Terauchi A, Strong C, Umemori H. 2015 Distinct sets of FGF receptors sculpt excitatory and inhibitory synaptogenesis. Development 142: 1818–1830
-
(2015)
Development
, vol.142
, pp. 1818-1830
-
-
Dabrowski, A.1
Terauchi, A.2
Strong, C.3
Umemori, H.4
-
40
-
-
84955209323
-
Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23
-
Degirolamo C, Sabba C, Moschetta A. 2016 Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23. Nat Rev Drug Discov 15: 51–69
-
(2016)
Nat Rev Drug Discov
, vol.15
, pp. 51-69
-
-
Degirolamo, C.1
Sabba, C.2
Moschetta, A.3
-
41
-
-
33846867972
-
ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation
-
Degoutin J, Vigny M, Gouzi JY. 2007 ALK activation induces Shc and FRS2 recruitment: signaling and phenotypic outcomes in PC12 cells differentiation. FEBS Lett 581: 727–734
-
(2007)
FEBS Lett
, vol.581
, pp. 727-734
-
-
Degoutin, J.1
Vigny, M.2
Gouzi, J.Y.3
-
42
-
-
23844468774
-
Control of the segmentation process by graded MAPK/ERK activation in the chick embryo
-
Delfini MC, Dubrulle J, Malapert P, Chal J, Pourquié O. 2005 Control of the segmentation process by graded MAPK/ERK activation in the chick embryo. Proc Natl Acad Sci 102: 11343–11348.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 11343-11348
-
-
Delfini, M.C.1
Dubrulle, J.2
Malapert, P.3
Chal, J.4
Pourquié, O.5
-
43
-
-
33646042252
-
Differential role of FGF9 on epithelium and mesenchyme in mouse embryonic lung
-
del Moral PM, De Langhe SP, Sala FG, Veltmaat JM, Tefft D, Wang K, Warburton D, Bellusci S. 2006 Differential role of FGF9 on epithelium and mesenchyme in mouse embryonic lung. Dev Biol 293: 77–89
-
(2006)
Dev Biol
, vol.293
, pp. 77-89
-
-
Del Moral, P.M.1
De Langhe, S.P.2
Sala, F.G.3
Veltmaat, J.M.4
Tefft, D.5
Wang, K.6
Warburton, D.7
Bellusci, S.8
-
44
-
-
0033961133
-
An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal- epithelial signalling during mouse organogenesis
-
De Moerlooze L, Spencer-Dene B, Revest JM, Hajihosseini M, Rosewell I, Dickson C. 2000 An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal- epithelial signalling during mouse organogenesis. Development 127: 483–492
-
(2000)
Development
, vol.127
, pp. 483-492
-
-
De Moerlooze, L.1
Spencer-Dene, B.2
Revest, J.M.3
Hajihosseini, M.4
Rosewell, I.5
Dickson, C.6
-
45
-
-
0028598814
-
Murine FGFR-1 is required for early postimplantation growth and axial organization
-
Deng CX, Wynshaw-Boris A, Shen MM, Daugherty C, Ornitz DM, Leder P. 1994 Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev 8: 3045–3057
-
(1994)
Genes Dev
, vol.8
, pp. 3045-3057
-
-
Deng, C.X.1
Wynshaw-Boris, A.2
Shen, M.M.3
Daugherty, C.4
Ornitz, D.M.5
Leder, P.6
-
46
-
-
0029917507
-
Fibroblast growth factor receptor 3 is a negative regulator of bone growth
-
Deng C, Wynshaw-Boris A, Zhou F, Kuo A, Leder P. 1996 Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84: 911–921
-
(1996)
Cell
, vol.84
, pp. 911-921
-
-
Deng, C.1
Wynshaw-Boris, A.2
Zhou, F.3
Kuo, A.4
Leder, P.5
-
47
-
-
0037077235
-
Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanism
-
Deo DD, Axelrad TW, Robert EG, Marcheselli V, Bazan NG, Hunt JD. 2002 Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanism. J Biol Chem 277: 21237–21245
-
(2002)
J Biol Chem
, vol.277
, pp. 21237-21245
-
-
Deo, D.D.1
Axelrad, T.W.2
Robert, E.G.3
Marcheselli, V.4
Bazan, N.G.5
Hunt, J.D.6
-
48
-
-
33845444174
-
A complex oscillating network of signaling genes underlies the mouse segmentation clock
-
Dequeant ML, Glynn E, Gaudenz K, Wahl M, Chen J, Mushegian A, Pourquié O. 2006 A complex oscillating network of signaling genes underlies the mouse segmentation clock. Science 314: 1595–1598
-
(2006)
Science
, vol.314
, pp. 1595-1598
-
-
Dequeant, M.L.1
Glynn, E.2
Gaudenz, K.3
Wahl, M.4
Chen, J.5
Mushegian, A.6
Pourquié, O.7
-
49
-
-
0033635195
-
Structural basis of SNT PTB domain interactions with distinct neurotrophic receptors
-
Dhalluin C, Yan KS, Plotnikova O, Lee KW, Zeng L, Kuti M, Mujtaba S, Goldfarb MP, Zhou MM. 2000 Structural basis of SNT PTB domain interactions with distinct neurotrophic receptors. Mol Cell 6: 921–929
-
(2000)
Mol Cell
, vol.6
, pp. 921-929
-
-
Dhalluin, C.1
Yan, K.S.2
Plotnikova, O.3
Lee, K.W.4
Zeng, L.5
Kuti, M.6
Mujtaba, S.7
Goldfarb, M.P.8
Zhou, M.M.9
-
50
-
-
20244366799
-
Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome
-
Dode C, Levilliers J, Dupont JM, De Paepe A, Le Du N, Soussi- Yanicostas N, Coimbra RS, Delmaghani S, Compain-Nouaille S, Baverel F, et al. 2003 Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome. Nat Genet 33: 463–465
-
(2003)
Nat Genet
, vol.33
, pp. 463-465
-
-
Dode, C.1
Levilliers, J.2
Dupont, J.M.3
De Paepe, A.4
Le Du, N.5
Soussi- Yanicostas, N.6
Coimbra, R.S.7
Delmaghani, S.8
Compain-Nouaille, S.9
Baverel, F.10
-
51
-
-
78149263789
-
FGF signalling: Diverse roles during early vertebrate embryogenesis
-
Dorey K, Amaya E. 2010 FGF signalling: diverse roles during early vertebrate embryogenesis. Development 137: 3731–3742
-
(2010)
Development
, vol.137
, pp. 3731-3742
-
-
Dorey, K.1
Amaya, E.2
-
52
-
-
0842264188
-
Fgf8 mRNAdecay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo
-
Dubrulle J, Pourquié O. 2004. fgf8 mRNAdecay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo. Nature 427: 419–422
-
(2004)
Nature
, vol.427
, pp. 419-422
-
-
Dubrulle, J.1
Pourquié, O.2
-
53
-
-
0035958586
-
FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation
-
Dubrulle J, McGrew MJ, Pourquié O. 2001 FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Cell 106: 219–232
-
(2001)
Cell
, vol.106
, pp. 219-232
-
-
Dubrulle, J.1
McGrew, M.J.2
Pourquié, O.3
-
54
-
-
77951043677
-
Signal transducers and activators of transcription-3 binding to the fibroblast growth factor receptor is activated by receptor amplification
-
Dudka AA, Sweet SM, Heath JK. 2010 Signal transducers and activators of transcription-3 binding to the fibroblast growth factor receptor is activated by receptor amplification. Cancer Res 70: 3391–3401
-
(2010)
Cancer Res
, vol.70
, pp. 3391-3401
-
-
Dudka, A.A.1
Sweet, S.M.2
Heath, J.K.3
-
55
-
-
34247261472
-
Skeletal overgrowth is mediated by deficiency in a specific isoform of fibroblast growth factor receptor 3
-
Eswarakumar VP, Schlessinger J. 2007 Skeletal overgrowth is mediated by deficiency in a specific isoform of fibroblast growth factor receptor 3. Proc Natl Acad Sci 104: 3937–3942
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 3937-3942
-
-
Eswarakumar, V.P.1
Schlessinger, J.2
-
56
-
-
0036671733
-
The IIIc alternative of Fgfr2 is a positive regulator of bone formation
-
Eswarakumar VP, Monsonego-Ornan E, Pines M, Antonopoulou I, Morriss-Kay GM, Lonai P. 2002 The IIIc alternative of Fgfr2 is a positive regulator of bone formation. Development 129: 3783–3793
-
(2002)
Development
, vol.129
, pp. 3783-3793
-
-
Eswarakumar, V.P.1
Monsonego-Ornan, E.2
Pines, M.3
Antonopoulou, I.4
Morriss-Kay, G.M.5
Lonai, P.6
-
57
-
-
33845475612
-
Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis
-
Eswarakumar VP, Ozcan F, Lew ED, Bae JH, Tome F, Booth CJ, Adams DJ, Lax I, Schlessinger J. 2006 Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis. Proc Natl Acad Sci 103: 18603–18608
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 18603-18608
-
-
Eswarakumar, V.P.1
Ozcan, F.2
Lew, E.D.3
Bae, J.H.4
Tome, F.5
Booth, C.J.6
Adams, D.J.7
Lax, I.8
Schlessinger, J.9
-
58
-
-
84878784688
-
The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes
-
Ezzat S, Zheng L, Florez JC, Stefan N, Mayr T, Hliang MM, Jablonski K, Harden M, Stancakova A, Laakso M, et al. 2013 The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes. Cell Metab 17: 929–940
-
(2013)
Cell Metab
, vol.17
, pp. 929-940
-
-
Ezzat, S.1
Zheng, L.2
Florez, J.C.3
Stefan, N.4
Mayr, T.5
Hliang, M.M.6
Jablonski, K.7
Harden, M.8
Stancakova, A.9
Laakso, M.10
-
59
-
-
0035199139
-
Fgf receptor signaling plays a role in lens induction
-
Faber SC, Dimanlig P, Makarenkova HP, Shirke S, Ko K, Lang RA. 2001 Fgf receptor signaling plays a role in lens induction. Development 128: 4425–4438
-
(2001)
Development
, vol.128
, pp. 4425-4438
-
-
Faber, S.C.1
Dimanlig, P.2
Makarenkova, H.P.3
Shirke, S.4
Ko, K.5
Lang, R.A.6
-
60
-
-
48749120107
-
Decreased FGF8 signaling causes deficiency of gonadotropin- releasing hormone in humans and mice
-
Falardeau J, Chung WC, Beenken A, Raivio T, Plummer L, Sidis Y, Jacobson-Dickman EE, Eliseenkova AV, Ma J, Dwyer A, et al. 2008 Decreased FGF8 signaling causes deficiency of gonadotropin- releasing hormone in humans and mice. J Clin Invest 118: 2822–2831
-
(2008)
J Clin Invest
, vol.118
, pp. 2822-2831
-
-
Falardeau, J.1
Chung, W.C.2
Beenken, A.3
Raivio, T.4
Plummer, L.5
Sidis, Y.6
Jacobson-Dickman, E.E.7
Eliseenkova, A.V.8
Ma, J.9
Dwyer, A.10
-
61
-
-
80555148939
-
FGF23 induces left ventricular hypertrophy
-
Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, Gutierrez OM, Aguillon-Prada R, Lincoln J, Hare JM, et al. 2011 FGF23 induces left ventricular hypertrophy. J Clin Invest 121: 4393–4408
-
(2011)
J Clin Invest
, vol.121
, pp. 4393-4408
-
-
Faul, C.1
Amaral, A.P.2
Oskouei, B.3
Hu, M.C.4
Sloan, A.5
Isakova, T.6
Gutierrez, O.M.7
Aguillon-Prada, R.8
Lincoln, J.9
Hare, J.M.10
-
62
-
-
0028910939
-
Requirement of FGF-4 for postimplantation mouse development
-
Feldman B, Poueymirou W, Papaioannou VE, DeChiara TM, Goldfarb M. 1995 Requirement of FGF-4 for postimplantation mouse development. Science 267: 246–249
-
(1995)
Science
, vol.267
, pp. 246-249
-
-
Feldman, B.1
Poueymirou, W.2
Papaioannou, V.E.3
Dechiara, T.M.4
Goldfarb, M.5
-
63
-
-
0035475308
-
Crk family adaptors-signalling complex formation and biological roles
-
Feller SM. 2001 Crk family adaptors-signalling complex formation and biological roles. Oncogene 20: 6348–6371
-
(2001)
Oncogene
, vol.20
, pp. 6348-6371
-
-
Feller, S.M.1
-
64
-
-
84884586861
-
Functional proteomics defines the molecular switch underlying FGF receptor trafficking and cellular outputs
-
Francavilla C, Rigbolt KT, Emdal KB, Carraro G, Vernet E, Bekker- Jensen DB, Streicher W, Wikstrom M, Sundstrom M, Bellusci S, et al. 2013 Functional proteomics defines the molecular switch underlying FGF receptor trafficking and cellular outputs. Mol Cell 51: 707–722
-
(2013)
Mol Cell
, vol.51
, pp. 707-722
-
-
Francavilla, C.1
Rigbolt, K.T.2
Emdal, K.B.3
Carraro, G.4
Vernet, E.5
Bekker- Jensen, D.B.6
Streicher, W.7
Wikstrom, M.8
Sundstrom, M.9
Bellusci, S.10
-
65
-
-
84947027572
-
Functional redundancy of ERK1 and ERK2MAPkinases during development
-
Fremin C, Saba-El-Leil MK, Levesque K, Ang SL, Meloche S. 2015 Functional redundancy of ERK1 and ERK2MAPkinases during development. Cell Rep 12: 913–921
-
(2015)
Cell Rep
, vol.12
, pp. 913-921
-
-
Fremin, C.1
Saba-El-Leil, M.K.2
Levesque, K.3
Ang, S.L.4
Meloche, S.5
-
66
-
-
33144455197
-
Expression of a dominant negative FGF receptor in developing GNRH1 neurons disrupts axon outgrowth and targeting to the median eminence
-
Gill JC, Tsai PS. 2006 Expression of a dominant negative FGF receptor in developing GNRH1 neurons disrupts axon outgrowth and targeting to the median eminence. Biol Reprod 74: 463–472
-
(2006)
Biol Reprod
, vol.74
, pp. 463-472
-
-
Gill, J.C.1
Tsai, P.S.2
-
67
-
-
0037644786
-
Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm
-
Goldin SN, Papaioannou VE. 2003 Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm. Genesis 36: 40–47
-
(2003)
Genesis
, vol.36
, pp. 40-47
-
-
Goldin, S.N.1
Papaioannou, V.E.2
-
68
-
-
10344231494
-
Tyrosine phosphorylation sites on FRS2α responsible for Shp2 recruitment are critical for induction of lens and retina
-
Gotoh N, Ito M, Yamamoto S, Yoshino I, Song N, Wang Y, Lax I, Schlessinger J, Shibuya M, Lang RA. 2004a. Tyrosine phosphorylation sites on FRS2α responsible for Shp2 recruitment are critical for induction of lens and retina. Proc Natl Acad Sci 101: 17144–17149
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 17144-17149
-
-
Gotoh, N.1
Ito, M.2
Yamamoto, S.3
Yoshino, I.4
Song, N.5
Wang, Y.6
Lax, I.7
Schlessinger, J.8
Shibuya, M.9
Lang, R.A.10
-
69
-
-
1842850649
-
FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts
-
Gotoh N, Laks S, Nakashima M, Lax I, Schlessinger J. 2004b. FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts. FEBS Lett 564: 14–18
-
(2004)
FEBS Lett
, vol.564
, pp. 14-18
-
-
Gotoh, N.1
Laks, S.2
Nakashima, M.3
Lax, I.4
Schlessinger, J.5
-
70
-
-
20144372283
-
The docking protein FRS2α is an essential component of multiplefibroblast growth factor responses during early mouse development
-
Gotoh N, Manova K, Tanaka S, Murohashi M, Hadari Y, Lee A, Hamada Y, Hiroe T, Ito M, Kurihara T, et al. 2005 The docking protein FRS2α is an essential component of multiplefibroblast growth factor responses during early mouse development. Mol Cell Biol 25: 4105–4116
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4105-4116
-
-
Gotoh, N.1
Manova, K.2
Tanaka, S.3
Murohashi, M.4
Hadari, Y.5
Lee, A.6
Hamada, Y.7
Hiroe, T.8
Ito, M.9
Kurihara, T.10
-
71
-
-
84945942478
-
Activation of cardiac fibroblast growth factor receptor 4 causes left ventricular hypertrophy
-
Grabner A, Amaral AP, Schramm K, Singh S, Sloan A, Yanucil C, Li J, Shehadeh LA, Hare JM, David V, et al. 2015 Activation of cardiac fibroblast growth factor receptor 4 causes left ventricular hypertrophy. Cell Metab 22: 1020–1032
-
(2015)
Cell Metab
, vol.22
, pp. 1020-1032
-
-
Grabner, A.1
Amaral, A.P.2
Schramm, K.3
Singh, S.4
Sloan, A.5
Yanucil, C.6
Li, J.7
Shehadeh, L.A.8
Hare, J.M.9
David, V.10
-
72
-
-
84872367040
-
Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules
-
Griffin JN, Compagnucci C, Hu D, Fish J, Klein O, Marcucio R, Depew MJ. 2013 Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules. Dev Biol 374: 185–197
-
(2013)
Dev Biol
, vol.374
, pp. 185-197
-
-
Griffin, J.N.1
Compagnucci, C.2
Hu, D.3
Fish, J.4
Klein, O.5
Marcucio, R.6
Depew, M.J.7
-
73
-
-
0027428744
-
Activating and inhibitory heparin sequences for FGF-2 (Basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4
-
Guimond S, Maccarana M, Olwin BB, Lindahl U, Rapraeger AC. 1993 Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4. J Biol Chem 268: 23906–23914
-
(1993)
J Biol Chem
, vol.268
, pp. 23906-23914
-
-
Guimond, S.1
Maccarana, M.2
Olwin, B.B.3
Lindahl, U.4
Rapraeger, A.C.5
-
74
-
-
0031835659
-
Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation
-
Hadari YR, Kouhara H, Lax I, Schlessinger J. 1998 Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation. Mol Cell Biol 18: 3966–3973
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3966-3973
-
-
Hadari, Y.R.1
Kouhara, H.2
Lax, I.3
Schlessinger, J.4
-
75
-
-
84930959593
-
The novel PKCθ from benchtop to clinic
-
Hage-Sleiman R, Hamze AB, Reslan L, Kobeissy H, Dbaibo G. 2015 The novel PKCθ from benchtop to clinic. J Immunol Res 2015: 348798
-
(2015)
J Immunol Res
, vol.2015
-
-
Hage-Sleiman, R.1
Hamze, A.B.2
Reslan, L.3
Kobeissy, H.4
Dbaibo, G.5
-
76
-
-
0035957343
-
A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes
-
Hajihosseini MK, Wilson S, De Moerlooze L, Dickson C. 2001 A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes. Proc Natl Acad Sci 98: 3855–3860
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 3855-3860
-
-
Hajihosseini, M.K.1
Wilson, S.2
De Moerlooze, L.3
Dickson, C.4
-
77
-
-
0026744679
-
Beare-Stevenson cutis gyrata syndrome
-
Hall BD, Cadle RG, Golabi M, Morris CA, Cohen MM Jr. 1992 Beare-Stevenson cutis gyrata syndrome. Am J Med Genet 44: 82–89
-
(1992)
Am J Med Genet
, vol.44
, pp. 82-89
-
-
Hall, B.D.1
Cadle, R.G.2
Golabi, M.3
Morris, C.A.4
Cohen, M.M.5
-
78
-
-
61349091627
-
FGF9 monomer–dimer equilibrium regulates extracellular matrix affinity and tissue diffusion
-
Harada M, Murakami H, Okawa A, Okimoto N, Hiraoka S, Nakahara T, Akasaka R, Shiraishi Y, Futatsugi N, Mizutani-Koseki Y, et al. 2009 FGF9 monomer–dimer equilibrium regulates extracellular matrix affinity and tissue diffusion. Nat Genet 41: 289–298
-
(2009)
Nat Genet
, vol.41
, pp. 289-298
-
-
Harada, M.1
Murakami, H.2
Okawa, A.3
Okimoto, N.4
Hiraoka, S.5
Nakahara, T.6
Akasaka, R.7
Shiraishi, Y.8
Futatsugi, N.9
Mizutani-Koseki, Y.10
-
79
-
-
0034612592
-
Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4
-
Hart KC, Robertson SC, Kanemitsu MY, Meyer AN, Tynan JA, Donoghue DJ. 2000 Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4. Oncogene 19: 3309–3320
-
(2000)
Oncogene
, vol.19
, pp. 3309-3320
-
-
Hart, K.C.1
Robertson, S.C.2
Kanemitsu, M.Y.3
Meyer, A.N.4
Tynan, J.A.5
Donoghue, D.J.6
-
80
-
-
0035168141
-
Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation
-
Hart KC, Robertson SC, Donoghue DJ. 2001 Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation. Mol Biol Cell 12: 931–942
-
(2001)
Mol Biol Cell
, vol.12
, pp. 931-942
-
-
Hart, K.C.1
Robertson, S.C.2
Donoghue, D.J.3
-
81
-
-
10744228332
-
Essential role for ERK2 mitogen-activated protein kinase in placental development
-
Hatano N, Mori Y, Oh-hora M, Kosugi A, Fujikawa T, Nakai N, Niwa H, Miyazaki J, Hamaoka T, Ogata M. 2003 Essential role for ERK2 mitogen-activated protein kinase in placental development. Genes Cells 8: 847–856
-
(2003)
Genes Cells
, vol.8
, pp. 847-856
-
-
Hatano, N.1
Mori, Y.2
Oh-Hora, M.3
Kosugi, A.4
Fujikawa, T.5
Nakai, N.6
Niwa, H.7
Miyazaki, J.8
Hamaoka, T.9
Ogata, M.10
-
82
-
-
66049115814
-
Sprouty4, an FGF inhibitor, displays cyclic gene expression under the control of the notch segmentation clock in the mouse PSM
-
Hayashi S, Shimoda T, Nakajima M, Tsukada Y, Sakumura Y, Dale JK, Maroto M, Kohno K, Matsui T, Bessho Y. 2009 Sprouty4, an FGF inhibitor, displays cyclic gene expression under the control of the notch segmentation clock in the mouse PSM. PLoS One 4: e5603
-
(2009)
Plos One
, vol.4
-
-
Hayashi, S.1
Shimoda, T.2
Nakajima, M.3
Tsukada, Y.4
Sakumura, Y.5
Dale, J.K.6
Maroto, M.7
Kohno, K.8
Matsui, T.9
Bessho, Y.10
-
83
-
-
0027931643
-
FGF5 as a regulator of the hair growth cycle: Evidence from targeted and spontaneous mutations
-
Hebert JM, Rosenquist T, Gotz J, Martin GR. 1994 FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations. Cell 78: 1017–1025
-
(1994)
Cell
, vol.78
, pp. 1017-1025
-
-
Hebert, J.M.1
Rosenquist, T.2
Gotz, J.3
Martin, G.R.4
-
84
-
-
84904707332
-
FGF5 is a crucial regulator of hair length in humans
-
Higgins CA, Petukhova L, Harel S, Ho YY, Drill E, Shapiro L, Wajid M, Christiano AM. 2014 FGF5 is a crucial regulator of hair length in humans. Proc Natl Acad Sci 111: 10648–10653
-
(2014)
Proc Natl Acad Sci
, vol.111
, pp. 10648-10653
-
-
Higgins, C.A.1
Petukhova, L.2
Harel, S.3
Ho, Y.Y.4
Drill, E.5
Shapiro, L.6
Wajid, M.7
Christiano, A.M.8
-
85
-
-
84922896900
-
Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
-
Hiratsuka T, Fujita Y, Naoki H, Aoki K, Kamioka Y, Matsuda M. 2015 Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin. Elife 4: e05178
-
(2015)
Elife
, vol.4
-
-
Hiratsuka, T.1
Fujita, Y.2
Naoki, H.3
Aoki, K.4
Kamioka, Y.5
Matsuda, M.6
-
86
-
-
33645068866
-
Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development
-
Hoch RV, Soriano P. 2006 Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development. Development 133: 663–673
-
(2006)
Development
, vol.133
, pp. 663-673
-
-
Hoch, R.V.1
Soriano, P.2
-
87
-
-
0037663483
-
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis
-
Holt JA, Luo G, Billin AN, Bisi J, McNeill YY, Kozarsky KF, Donahee M, Wang DY, Mansfield TA, Kliewer SA, et al. 2003 Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Genes Dev 17: 1581–1591
-
(2003)
Genes Dev
, vol.17
, pp. 1581-1591
-
-
Holt, J.A.1
Luo, G.2
Billin, A.N.3
Bisi, J.4
McNeill, Y.Y.5
Kozarsky, K.F.6
Donahee, M.7
Wang, D.Y.8
Mansfield, T.A.9
Kliewer, S.A.10
-
88
-
-
84871678213
-
GnRH neuronal migration and olfactory bulb neurite outgrowth are dependent on FGF receptor 1 signaling, specifically via the PI3K p110α isoform in chick embryo
-
Hu Y, Poopalasundaram S, Graham A, Bouloux PM. 2013 GnRH neuronal migration and olfactory bulb neurite outgrowth are dependent on FGF receptor 1 signaling, specifically via the PI3K p110α isoform in chick embryo. Endocrinology 154: 388–399
-
(2013)
Endocrinology
, vol.154
, pp. 388-399
-
-
Hu, Y.1
Poopalasundaram, S.2
Graham, A.3
Bouloux, P.M.4
-
89
-
-
18144421574
-
FGF signaling in flies and worms: More and more relevant to vertebrate biology
-
Huang P, Stern MJ. 2005 FGF signaling in flies and worms: more and more relevant to vertebrate biology. Cytokine Growth Factor Rev 16: 151–158
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 151-158
-
-
Huang, P.1
Stern, M.J.2
-
90
-
-
0028986599
-
Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis
-
Huang J, Mohammadi M, Rodrigues GA, Schlessinger J. 1995 Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis. J Biol Chem 270: 5065–5072
-
(1995)
J Biol Chem
, vol.270
, pp. 5065-5072
-
-
Huang, J.1
Mohammadi, M.2
Rodrigues, G.A.3
Schlessinger, J.4
-
91
-
-
84908222357
-
Signalling dynamics in vertebrate segmentation
-
Hubaud A, Pourquié O. 2014 Signalling dynamics in vertebrate segmentation. Nat Rev Mol Cell Biol 15: 709–721
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 709-721
-
-
Hubaud, A.1
Pourquié, O.2
-
92
-
-
84856448427
-
Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal
-
Huh SH, Jones J, Warchol ME, Ornitz DM. 2012 Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal. PLoS Biol 10: e1001231
-
(2012)
Plos Biol
, vol.10
-
-
Huh, S.H.1
Jones, J.2
Warchol, M.E.3
Ornitz, D.M.4
-
93
-
-
0032557548
-
Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7)
-
Igarashi M, Finch PW, Aaronson SA. 1998 Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7). J Biol Chem 273: 13230–13235
-
(1998)
J Biol Chem
, vol.273
, pp. 13230-13235
-
-
Igarashi, M.1
Finch, P.W.2
Aaronson, S.A.3
-
94
-
-
27844546989
-
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
-
Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, et al. 2005 Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab 2: 217–225
-
(2005)
Cell Metab
, vol.2
, pp. 217-225
-
-
Inagaki, T.1
Choi, M.2
Moschetta, A.3
Peng, L.4
Cummins, C.L.5
McDonald, J.G.6
Luo, G.7
Jones, S.A.8
Goodwin, B.9
Richardson, J.A.10
-
95
-
-
35349007958
-
The Fgf families in humans, mice, and zebrafish: Their evolutional processes and roles in development, metabolism, and disease
-
Itoh N. 2007 The Fgf families in humans, mice, and zebrafish: their evolutional processes and roles in development, metabolism, and disease. Biol Pharm Bulletin 30: 1819–1825
-
(2007)
Biol Pharm Bulletin
, vol.30
, pp. 1819-1825
-
-
Itoh, N.1
-
96
-
-
84962366018
-
Endocrine FGFs: Evolution, physiology, pathophysiology, and pharmacotherapy
-
Itoh N, Ohta H, Konishi M. 2015 Endocrine FGFs: evolution, physiology, pathophysiology, and pharmacotherapy. Front Endocrinol 6: 154
-
(2015)
Front Endocrinol
, vol.6
, pp. 154
-
-
Itoh, N.1
Ohta, H.2
Konishi, M.3
-
97
-
-
4444324911
-
A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasia
-
Jijiwa M, Fukuda T, Kawai K, Nakamura A, Kurokawa K, Murakumo Y, Ichihara M, Takahashi M. 2004 A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasia. Mol Cell Biol 24: 8026–8036
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8026-8036
-
-
Jijiwa, M.1
Fukuda, T.2
Kawai, K.3
Nakamura, A.4
Kurokawa, K.5
Murakumo, Y.6
Ichihara, M.7
Takahashi, M.8
-
98
-
-
0025912340
-
The human fibroblast growth factor receptor genes: A common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain
-
Johnson DE, Lu J, Chen H, Werner S, Williams LT. 1991 The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain. Mol Cell Biol 11: 4627–4634
-
(1991)
Mol Cell Biol
, vol.11
, pp. 4627-4634
-
-
Johnson, D.E.1
Lu, J.2
Chen, H.3
Werner, S.4
Williams, L.T.5
-
99
-
-
84855775666
-
The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition
-
Kalinina J, Dutta K, Ilghari D, Beenken A, Goetz R, Eliseenkova AV, Cowburn D, Mohammadi M. 2012 The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition. Structure (London, England: 1993) 20: 77–88
-
(2012)
Structure (London, England: 1993
, vol.20
, pp. 77-88
-
-
Kalinina, J.1
Dutta, K.2
Ilghari, D.3
Beenken, A.4
Goetz, R.5
Eliseenkova, A.V.6
Cowburn, D.7
Mohammadi, M.8
-
100
-
-
84871561933
-
FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse
-
Kang M, Piliszek A, Artus J, Hadjantonakis AK. 2013 FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse. Development 140: 267–279
-
(2013)
Development
, vol.140
, pp. 267-279
-
-
Kang, M.1
Piliszek, A.2
Artus, J.3
Hadjantonakis, A.K.4
-
101
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
Kharitonenkov A, Shiyanova TL, Koester A, Ford AM, Micanovic R, Galbreath EJ, Sandusky GE, Hammond LJ, Moyers JS, Owens RA, et al. 2005 FGF-21 as a novel metabolic regulator. J Clin Invest 115: 1627–1635
-
(2005)
J Clin Invest
, vol.115
, pp. 1627-1635
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
Sandusky, G.E.7
Hammond, L.J.8
Moyers, J.S.9
Owens, R.A.10
-
102
-
-
0037414760
-
The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2
-
Kim HJ, Kim JH, Bae SC, Choi JY, Kim HJ, Ryoo HM. 2003 The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2. J Biol Chem 278: 319–326
-
(2003)
J Biol Chem
, vol.278
, pp. 319-326
-
-
Kim, H.J.1
Kim, J.H.2
Bae, S.C.3
Choi, J.Y.4
Kim, H.J.5
Ryoo, H.M.6
-
103
-
-
0036007120
-
An allelic series at the PDGFαR locus indicates unequalcontributions of distinct signaling pathways during development
-
Klinghoffer RA, Hamilton TG, Hoch R, Soriano P. 2002 An allelic series at the PDGFαR locus indicates unequalcontributions of distinct signaling pathways during development. Dev Cell 2: 103–113
-
(2002)
Dev Cell
, vol.2
, pp. 103-113
-
-
Klinghoffer, R.A.1
Hamilton, T.G.2
Hoch, R.3
Soriano, P.4
-
104
-
-
0040627311
-
Contribution of Src and Ras pathways in FGF-2 induced endothelial cell differentiation
-
Klint P, Kanda S, Kloog Y, Claesson-Welsh L. 1999 Contribution of Src and Ras pathways in FGF-2 induced endothelial cell differentiation. Oncogene 18: 3354–3364
-
(1999)
Oncogene
, vol.18
, pp. 3354-3364
-
-
Klint, P.1
Kanda, S.2
Kloog, Y.3
Claesson-Welsh, L.4
-
105
-
-
0037013284
-
Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation
-
Kong M, Wang CS, Donoghue DJ. 2002 Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation. J Biol Chem 277: 15962–15970
-
(2002)
J Biol Chem
, vol.277
, pp. 15962-15970
-
-
Kong, M.1
Wang, C.S.2
Donoghue, D.J.3
-
106
-
-
0030706168
-
A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
-
Kouhara H, Hadari YR, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I, Schlessinger J. 1997 A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89: 693–702
-
(1997)
Cell
, vol.89
, pp. 693-702
-
-
Kouhara, H.1
Hadari, Y.R.2
Spivak-Kroizman, T.3
Schilling, J.4
Bar-Sagi, D.5
Lax, I.6
Schlessinger, J.7
-
107
-
-
40549114946
-
STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes
-
Krejci P, Salazar L, Goodridge HS, Kashiwada TA, Schibler MJ, Jelinkova P, Thompson LM, Wilcox WR. 2008 STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes. J Cell Sci 121: 272–281
-
(2008)
J Cell Sci
, vol.121
, pp. 272-281
-
-
Krejci, P.1
Salazar, L.2
Goodridge, H.S.3
Kashiwada, T.A.4
Schibler, M.J.5
Jelinkova, P.6
Thompson, L.M.7
Wilcox, W.R.8
-
108
-
-
0035848684
-
Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction
-
Kurokawa K, Iwashita T, Murakami H, Hayashi H, Kawai K, Takahashi M. 2001 Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction. Oncogene 20: 1929–1938
-
(2001)
Oncogene
, vol.20
, pp. 1929-1938
-
-
Kurokawa, K.1
Iwashita, T.2
Murakami, H.3
Hayashi, H.4
Kawai, K.5
Takahashi, M.6
-
109
-
-
33646578195
-
Regulation of fibroblast growth factor-23 signaling by klotho
-
Kurosu H, Ogawa Y, Miyoshi M, Yamamoto M, Nandi A, Rosenblatt KP, Baum MG, Schiavi S, Hu MC, Moe OW, et al. 2006 Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 281: 6120–6123
-
(2006)
J Biol Chem
, vol.281
, pp. 6120-6123
-
-
Kurosu, H.1
Ogawa, Y.2
Miyoshi, M.3
Yamamoto, M.4
Nandi, A.5
Rosenblatt, K.P.6
Baum, M.G.7
Schiavi, S.8
Hu, M.C.9
Moe, O.W.10
-
110
-
-
0033520278
-
Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk
-
Larsson H, Klint P, Landgren E, Claesson-Welsh L. 1999 Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk. J Biol Chem 274: 25726–25734
-
(1999)
J Biol Chem
, vol.274
, pp. 25726-25734
-
-
Larsson, H.1
Klint, P.2
Landgren, E.3
Claesson-Welsh, L.4
-
111
-
-
0024375271
-
Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor
-
Lee PL, Johnson DE, Cousens LS, Fried VA, Williams LT. 1989 Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science 245: 57–60
-
(1989)
Science
, vol.245
, pp. 57-60
-
-
Lee, P.L.1
Johnson, D.E.2
Cousens, L.S.3
Fried, V.A.4
Williams, L.T.5
-
112
-
-
0030933498
-
Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain
-
Lee SM, Danielian PS, Fritzsch B, McMahon AP. 1997 Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development 124: 959–969
-
(1997)
Development
, vol.124
, pp. 959-969
-
-
Lee, S.M.1
Danielian, P.S.2
Fritzsch, B.3
McMahon, A.P.4
-
113
-
-
0033673531
-
Fgf8 signalling fromthe AER is essential for normal limb development
-
Lewandoski M, Sun X, Martin GR. 2000 Fgf8 signalling fromthe AER is essential for normal limb development. Nat Genet 26: 460–463
-
(2000)
Nat Genet
, vol.26
, pp. 460-463
-
-
Lewandoski, M.1
Sun, X.2
Martin, G.R.3
-
114
-
-
0032938128
-
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors
-
Li C, Chen L, Iwata T, Kitagawa M, Fu XY, Deng CX. 1999 A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors. Hum Mol Genet 8: 35–44
-
(1999)
Hum Mol Genet
, vol.8
, pp. 35-44
-
-
Li, C.1
Chen, L.2
Iwata, T.3
Kitagawa, M.4
Fu, X.Y.5
Deng, C.X.6
-
115
-
-
12344278405
-
FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity
-
Li X, Brunton VG, Burgar HR, Wheldon LM, Heath JK. 2004 FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity. J Cell Sci 117: 6007–6017
-
(2004)
J Cell Sci
, vol.117
, pp. 6007-6017
-
-
Li, X.1
Brunton, V.G.2
Burgar, H.R.3
Wheldon, L.M.4
Heath, J.K.5
-
116
-
-
84862669198
-
Inhibition of basal FGF receptor signaling by dimeric Grb2
-
Lin CC, Melo FA, Ghosh R, Suen KM, Stagg LJ, Kirkpatrick J, Arold ST, Ahmed Z, Ladbury JE. 2012 Inhibition of basal FGF receptor signaling by dimeric Grb2. Cell 149: 1514–1524
-
(2012)
Cell
, vol.149
, pp. 1514-1524
-
-
Lin, C.C.1
Melo, F.A.2
Ghosh, R.3
Suen, K.M.4
Stagg, L.J.5
Kirkpatrick, J.6
Arold, S.T.7
Ahmed, Z.8
Ladbury, J.E.9
-
117
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulinlike growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
-
Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. 1993 Mice carrying null mutations of the genes encoding insulinlike growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75: 59–72
-
(1993)
Cell
, vol.75
, pp. 59-72
-
-
Liu, J.P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
118
-
-
0032708854
-
FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate
-
Liu A, Losos K, Joyner AL. 1999a. FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development 126: 4827–4838
-
(1999)
Development
, vol.126
, pp. 4827-4838
-
-
Liu, A.1
Losos, K.2
Joyner, A.L.3
-
119
-
-
0033581955
-
Src is required for cell migration and shape changes induced by fibroblast growth factor 1
-
Liu J, Huang C, Zhan X. 1999b. Src is required for cell migration and shape changes induced by fibroblast growth factor 1. Oncogene 18: 6700–6706
-
(1999)
Oncogene
, vol.18
, pp. 6700-6706
-
-
Liu, J.1
Huang, C.2
Zhan, X.3
-
120
-
-
0036203355
-
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18
-
Liu Z, Xu J, Colvin JS, Ornitz DM. 2002 Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev 16: 859–869
-
(2002)
Genes Dev
, vol.16
, pp. 859-869
-
-
Liu, Z.1
Xu, J.2
Colvin, J.S.3
Ornitz, D.M.4
-
121
-
-
0028882525
-
FGF-8 isoforms activate receptor splice forms that are expressed in mesenchymal regions of mouse development
-
MacArthur CA, Lawshe A, Xu J, Santos-Ocampo S, Heikinheimo M, Chellaiah AT, Ornitz DM. 1995 FGF-8 isoforms activate receptor splice forms that are expressed in mesenchymal regions of mouse development. Development 121: 3603–3613
-
(1995)
Development
, vol.121
, pp. 3603-3613
-
-
Macarthur, C.A.1
Lawshe, A.2
Xu, J.3
Santos-Ocampo, S.4
Heikinheimo, M.5
Chellaiah, A.T.6
Ornitz, D.M.7
-
122
-
-
73949157671
-
Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis
-
Makarenkova HP, Hoffman MP, Beenken A, Eliseenkova AV, Meech R, Tsau C, Patel VN, Lang RA, Mohammadi M. 2009 Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis. Sci Signal 2: ra55
-
(2009)
Sci Signal
, vol.2
-
-
Makarenkova, H.P.1
Hoffman, M.P.2
Beenken, A.3
Eliseenkova, A.V.4
Meech, R.5
Tsau, C.6
Patel, V.N.7
Lang, R.A.8
Mohammadi, M.9
-
123
-
-
57749109181
-
Hearing loss in a mouse model of Muenke syndrome
-
Mansour SL, Twigg SR, Freeland RM, Wall SA, Li C, Wilkie AO. 2009 Hearing loss in a mouse model of Muenke syndrome. Hum Mol Genet 18: 43–50
-
(2009)
Hum Mol Genet
, vol.18
, pp. 43-50
-
-
Mansour, S.L.1
Twigg, S.R.2
Freeland, R.M.3
Wall, S.A.4
Li, C.5
Wilkie, A.O.6
-
124
-
-
43749110077
-
Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning
-
Mariani FV, Ahn CP, Martin GR. 2008 Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning. Nature 453: 401–405
-
(2008)
Nature
, vol.453
, pp. 401-405
-
-
Mariani, F.V.1
Ahn, C.P.2
Martin, G.R.3
-
125
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall CJ. 1995 Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80: 179–185
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
126
-
-
34447634477
-
Initiation to end point: The multiple roles of fibroblast growth factors in neural development
-
Mason I. 2007 Initiation to end point: the multiple roles of fibroblast growth factors in neural development. Nat Rev Neurosci 8: 583–596
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 583-596
-
-
Mason, I.1
-
127
-
-
0034967978
-
Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade
-
Melillo RM, Santoro M, Ong SH, Billaud M, Fusco A, Hadari YR, Schlessinger J, Lax I. 2001 Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade. Mol Cell Biol 21: 4177–4187
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4177-4187
-
-
Melillo, R.M.1
Santoro, M.2
Ong, S.H.3
Billaud, M.4
Fusco, A.5
Hadari, Y.R.6
Schlessinger, J.7
Lax, I.8
-
128
-
-
0026570847
-
Determination of ligand-binding specificity by alternative splicing: Two distinct growth factor receptors encoded by a single gene
-
Miki T, Bottaro DP, Fleming TP, Smith CL, Burgess WH, Chan AM, Aaronson SA. 1992 Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci 89: 246–250
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 246-250
-
-
Miki, T.1
Bottaro, D.P.2
Fleming, T.P.3
Smith, C.L.4
Burgess, W.H.5
Chan, A.M.6
Aaronson, S.A.7
-
129
-
-
0032532479
-
Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless
-
Min H, Danilenko DM, Scully SA, Bolon B, Ring BD, Tarpley JE, DeRose M, Simonet WS. 1998 Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev 12: 3156–3161
-
(1998)
Genes Dev
, vol.12
, pp. 3156-3161
-
-
Min, H.1
Danilenko, D.M.2
Scully, S.A.3
Bolon, B.4
Ring, B.D.5
Tarpley, J.E.6
Derose, M.7
Simonet, W.S.8
-
130
-
-
0025941527
-
A tyrosine- phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-γ1
-
Mohammadi M, Honegger AM, Rotin D, Fischer R, Bellot F, Li W, Dionne CA, Jaye M, Rubinstein M, Schlessinger J. 1991 A tyrosine- phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-γ1. Mol Cell Biol 11: 5068–5078
-
(1991)
Mol Cell Biol
, vol.11
, pp. 5068-5078
-
-
Mohammadi, M.1
Honegger, A.M.2
Rotin, D.3
Fischer, R.4
Bellot, F.5
Li, W.6
Dionne, C.A.7
Jaye, M.8
Rubinstein, M.9
Schlessinger, J.10
-
131
-
-
0026641249
-
Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis
-
Mohammadi M, Dionne CA, Li W, Li N, Spivak T, Honegger AM, Jaye M, Schlessinger J. 1992 Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature 358: 681–684
-
(1992)
Nature
, vol.358
, pp. 681-684
-
-
Mohammadi, M.1
Dionne, C.A.2
Li, W.3
Li, N.4
Spivak, T.5
Honegger, A.M.6
Jaye, M.7
Schlessinger, J.8
-
132
-
-
0032540267
-
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
-
Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN. 1998 A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93: 215–228
-
(1998)
Cell
, vol.93
, pp. 215-228
-
-
Molkentin, J.D.1
Lu, J.R.2
Antos, C.L.3
Markham, B.4
Richardson, J.5
Robbins, J.6
Grant, S.R.7
Olson, E.N.8
-
133
-
-
29744440528
-
Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes
-
Moon AM, Guris DL, Seo JH, Li L, Hammond J, Talbot A, Imamoto A. 2006 Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes. Dev Cell 10: 71–80
-
(2006)
Dev Cell
, vol.10
, pp. 71-80
-
-
Moon, A.M.1
Guris, D.L.2
Seo, J.H.3
Li, L.4
Hammond, J.5
Talbot, A.6
Imamoto, A.7
-
134
-
-
0034641614
-
Essential role for p38α mitogen-activated protein kinase in placental angiogenesis
-
Mudgett JS, Ding J, Guh-Siesel L, Chartrain NA, Yang L, Gopal S, Shen MM. 2000 Essential role for p38α mitogen-activated protein kinase in placental angiogenesis. Proc Natl Acad Sci 97: 10454–10459
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 10454-10459
-
-
Mudgett, J.S.1
Ding, J.2
Guh-Siesel, L.3
Chartrain, N.A.4
Yang, L.5
Gopal, S.6
Shen, M.M.7
-
135
-
-
1042289662
-
Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype
-
Murakami S, Balmes G, McKinney S, Zhang Z, Givol D, de Crombrugghe B. 2004 Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. Genes Dev 18: 290–305
-
(2004)
Genes Dev
, vol.18
, pp. 290-305
-
-
Murakami, S.1
Balmes, G.2
McKinney, S.3
Zhang, Z.4
Givol, D.5
De Crombrugghe, B.6
-
136
-
-
79951680614
-
FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis
-
Naiche LA, Holder N, Lewandoski M. 2011 FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis. Proc Natl Acad Sci 108: 4018–4023
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. 4018-4023
-
-
Naiche, L.A.1
Holder, N.2
Lewandoski, M.3
-
137
-
-
67650495042
-
Protein tyrosine phosphatase activity in the neural crest is essential fornormal heart and skull development
-
Nakamura T, Gulick J, Colbert MC, Robbins J. 2009 Protein tyrosine phosphatase activity in the neural crest is essential fornormal heart and skull development. Proc Natl Acad Sci 106: 11270–11275
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 11270-11275
-
-
Nakamura, T.1
Gulick, J.2
Colbert, M.C.3
Robbins, J.4
-
138
-
-
0032413011
-
Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3
-
Naski MC, Colvin JS, Coffin JD, Ornitz DM. 1998 Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3. Development 125: 4977–4988
-
(1998)
Development
, vol.125
, pp. 4977-4988
-
-
Naski, M.C.1
Colvin, J.S.2
Coffin, J.D.3
Ornitz, D.M.4
-
140
-
-
55949088852
-
Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development
-
Newbern J, Zhong J, Wickramasinghe RS, Li X, Wu Y, Samuels I, Cherosky N, Karlo JC, O’Loughlin B, Wikenheiser J, et al. 2008 Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development. Proc Natl Acad Sci 105: 17115–17120
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 17115-17120
-
-
Newbern, J.1
Zhong, J.2
Wickramasinghe, R.S.3
Li, X.4
Wu, Y.5
Samuels, I.6
Cherosky, N.7
Karlo, J.C.8
O’Loughlin, B.9
Wikenheiser, J.10
-
141
-
-
70349934958
-
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
-
Nichols J, Silva J, Roode M, Smith A. 2009 Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development 136: 3215–3222
-
(2009)
Development
, vol.136
, pp. 3215-3222
-
-
Nichols, J.1
Silva, J.2
Roode, M.3
Smith, A.4
-
142
-
-
84878230511
-
The regulation of runt-related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/ protein kinase Cδ cascade
-
Niger C, Luciotti MA, Buo AM, Hebert C, Ma V, Stains JP. 2013 The regulation of runt-related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/ protein kinase Cδ cascade. J Bone Miner Res 28: 1468–1477
-
(2013)
J Bone Miner Res
, vol.28
, pp. 1468-1477
-
-
Niger, C.1
Luciotti, M.A.2
Buo, A.M.3
Hebert, C.4
Ma, V.5
Stains, J.P.6
-
143
-
-
34547418278
-
The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock
-
Niwa Y, Masamizu Y, Liu T, Nakayama R, Deng CX, Kageyama R. 2007 The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock. Dev Cell 13: 298–304
-
(2007)
Dev Cell
, vol.13
, pp. 298-304
-
-
Niwa, Y.1
Masamizu, Y.2
Liu, T.3
Nakayama, R.4
Deng, C.X.5
Kageyama, R.6
-
144
-
-
79958056964
-
Different types of oscillations in Notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis
-
Niwa Y, Shimojo H, Isomura A, Gonzalez A, Miyachi H, Kageyama R. 2011 Different types of oscillations in Notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis. Genes Dev 25: 1115–1120
-
(2011)
Genes Dev
, vol.25
, pp. 1115-1120
-
-
Niwa, Y.1
Shimojo, H.2
Isomura, A.3
Gonzalez, A.4
Miyachi, H.5
Kageyama, R.6
-
145
-
-
34249697012
-
βKlotho is required for metabolic activity of fibroblast growth factor 21
-
Ogawa Y, Kurosu H, Yamamoto M, Nandi A, Rosenblatt KP, Goetz R, Eliseenkova AV, Mohammadi M, Kuro-o M. 2007. βKlotho is required for metabolic activity of fibroblast growth factor 21. Proc Natl Acad Sci 104: 7432–7437
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 7432-7437
-
-
Ogawa, Y.1
Kurosu, H.2
Yamamoto, M.3
Nandi, A.4
Rosenblatt, K.P.5
Goetz, R.6
Eliseenkova, A.V.7
Mohammadi, M.8
Kuro-O, M.9
-
146
-
-
0036205735
-
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
-
Ohbayashi N, Shibayama M, Kurotaki Y, Imanishi M, Fujimori T, Itoh N, Takada S. 2002 FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev 16: 870–879
-
(2002)
Genes Dev
, vol.16
, pp. 870-879
-
-
Ohbayashi, N.1
Shibayama, M.2
Kurotaki, Y.3
Imanishi, M.4
Fujimori, T.5
Itoh, N.6
Takada, S.7
-
147
-
-
0141780824
-
Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs
-
Olsen SK, Garbi M, Zampieri N, Eliseenkova AV, Ornitz DM, Goldfarb M, Mohammadi M. 2003 Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs. J Biol Chem 278: 34226–34236
-
(2003)
J Biol Chem
, vol.278
, pp. 34226-34236
-
-
Olsen, S.K.1
Garbi, M.2
Zampieri, N.3
Eliseenkova, A.V.4
Ornitz, D.M.5
Goldfarb, M.6
Mohammadi, M.7
-
148
-
-
30944448671
-
Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
-
Olsen SK, Li JY, Bromleigh C, Eliseenkova AV, Ibrahimi OA, Lao Z, Zhang F, Linhardt RJ, Joyner AL, Mohammadi M. 2006 Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain. Genes Dev 20: 185–198
-
(2006)
Genes Dev
, vol.20
, pp. 185-198
-
-
Olsen, S.K.1
Li, J.Y.2
Bromleigh, C.3
Eliseenkova, A.V.4
Ibrahimi, O.A.5
Lao, Z.6
Zhang, F.7
Linhardt, R.J.8
Joyner, A.L.9
Mohammadi, M.10
-
149
-
-
0001056526
-
Suc1-associated neurotrophic factor target (SNT) protein is a major FGF-stimulated tyrosine phosphorylated 90-kDa protein which binds to the SH2 domain of GRB2
-
Ong SH, Goh KC, Lim YP, Low BC, Klint P, Claesson-Welsh L, Cao X, Tan YH, Guy GR. 1996 Suc1-associated neurotrophic factor target (SNT) protein is a major FGF-stimulated tyrosine phosphorylated 90-kDa protein which binds to the SH2 domain of GRB2. Biochem Biophys Res Commun 225: 1021–1026
-
(1996)
Biochem Biophys Res Commun
, vol.225
, pp. 1021-1026
-
-
Ong, S.H.1
Goh, K.C.2
Lim, Y.P.3
Low, B.C.4
Klint, P.5
Claesson-Welsh, L.6
Cao, X.7
Tan, Y.H.8
Guy, G.R.9
-
150
-
-
0033974109
-
FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors
-
Ong SH, Guy GR, Hadari YR, Laks S, Gotoh N, Schlessinger J, Lax I. 2000 FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. Mol Cell Biol 20: 979–989
-
(2000)
Mol Cell Biol
, vol.20
, pp. 979-989
-
-
Ong, S.H.1
Guy, G.R.2
Hadari, Y.R.3
Laks, S.4
Gotoh, N.5
Schlessinger, J.6
Lax, I.7
-
151
-
-
0035933094
-
Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins
-
Ong SH, Hadari YR, Gotoh N, Guy GR, Schlessinger J, Lax I. 2001 Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins. Proc Natl Acad Sci 98: 6074–6079
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 6074-6079
-
-
Ong, S.H.1
Hadari, Y.R.2
Gotoh, N.3
Guy, G.R.4
Schlessinger, J.5
Lax, I.6
-
152
-
-
84893763965
-
FGFR1–Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation
-
Ono K, Kita T, Sato S, O’Neill P, Mak SS, Paschaki M, Ito M, Gotoh N, Kawakami K, Sasai Y, et al. 2014 FGFR1–Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation. PLoS Genet 10: e1004118
-
(2014)
Plos Genet
, vol.10
-
-
Ono, K.1
Kita, T.2
Sato, S.3
O’Neill, P.4
Mak, S.S.5
Paschaki, M.6
Ito, M.7
Gotoh, N.8
Kawakami, K.9
Sasai, Y.10
-
153
-
-
0033951768
-
FGFs, heparan sulfate and FGFRs: Complex interactions essential for development
-
Ornitz DM. 2000 FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays 22: 108–112
-
(2000)
Bioessays
, vol.22
, pp. 108-112
-
-
Ornitz, D.M.1
-
155
-
-
0026665252
-
Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3
-
Ornitz DM, Leder P. 1992 Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3. J Biol Chem 267: 16305–16311
-
(1992)
J Biol Chem
, vol.267
, pp. 16305-16311
-
-
Ornitz, D.M.1
Leder, P.2
-
156
-
-
84938151232
-
Fibroblast growth factor signaling in skeletal development and disease
-
Ornitz DM, Marie PJ. 2015 Fibroblast growth factor signaling in skeletal development and disease. Genes Development 29: 1463–1486
-
(2015)
Genes Development
, vol.29
, pp. 1463-1486
-
-
Ornitz, D.M.1
Marie, P.J.2
-
157
-
-
15844368097
-
Receptor specificity of the fibroblast growth factor family
-
Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M. 1996 Receptor specificity of the fibroblast growth factor family. J Biol Chem 271: 15292–15297
-
(1996)
J Biol Chem
, vol.271
, pp. 15292-15297
-
-
Ornitz, D.M.1
Xu, J.2
Colvin, J.S.3
McEwen, D.G.4
Macarthur, C.A.5
Coulier, F.6
Gao, G.7
Goldfarb, M.8
-
158
-
-
0026344226
-
Developmental expression of two murine fibroblast growth factor receptors, flg and bek
-
Orr-Urtreger A, Givol D, Yayon A, Yarden Y, Lonai P. 1991 Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development 113: 1419–1434
-
(1991)
Development
, vol.113
, pp. 1419-1434
-
-
Orr-Urtreger, A.1
Givol, D.2
Yayon, A.3
Yarden, Y.4
Lonai, P.5
-
159
-
-
17144458301
-
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
-
Pages G, Guerin S, Grall D, Bonino F, Smith A, Anjuere F, Auberger P, Pouyssegur J. 1999 Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 286: 1374–1377
-
(1999)
Science
, vol.286
, pp. 1374-1377
-
-
Pages, G.1
Guerin, S.2
Grall, D.3
Bonino, F.4
Smith, A.5
Anjuere, F.6
Auberger, P.7
Pouyssegur, J.8
-
160
-
-
57349132224
-
An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart
-
Park EJ, Watanabe Y, Smyth G, Miyagawa-Tomita S, Meyers E, Klingensmith J, Camenisch T, Buckingham M, Moon AM. 2008 An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart. Development 135: 3599–3610
-
(2008)
Development
, vol.135
, pp. 3599-3610
-
-
Park, E.J.1
Watanabe, Y.2
Smyth, G.3
Miyagawa-Tomita, S.4
Meyers, E.5
Klingensmith, J.6
Camenisch, T.7
Buckingham, M.8
Moon, A.M.9
-
161
-
-
0032146074
-
Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos
-
Partanen J, Schwartz L, Rossant J. 1998 Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. Genes Dev 12: 2332–2344
-
(1998)
Genes Dev
, vol.12
, pp. 2332-2344
-
-
Partanen, J.1
Schwartz, L.2
Rossant, J.3
-
162
-
-
38349091953
-
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis
-
Patel VN, Knox SM, Likar KM, Lathrop CA, Hossain R, Eftekhari S, Whitelock JM, Elkin M, Vlodavsky I, Hoffman MP. 2007 Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis. Development 134: 4177–4186
-
(2007)
Development
, vol.134
, pp. 4177-4186
-
-
Patel, V.N.1
Knox, S.M.2
Likar, K.M.3
Lathrop, C.A.4
Hossain, R.5
Eftekhari, S.6
Whitelock, J.M.7
Elkin, M.8
Vlodavsky, I.9
Hoffman, M.P.10
-
163
-
-
11844262678
-
Hush puppy: A new mouse mutant with pinna, ossicle, and inner ear defects
-
Pau H, Fuchs H, de Angelis MH, Steel KP. 2005 Hush puppy: a new mouse mutant with pinna, ossicle, and inner ear defects. Laryngoscope 115: 116–124
-
(2005)
Laryngoscope
, vol.115
, pp. 116-124
-
-
Pau, H.1
Fuchs, H.2
De Angelis, M.H.3
Steel, K.P.4
-
164
-
-
0026731562
-
Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis
-
Peters KG, Marie J, Wilson E, Ives HE, Escobedo J, Del Rosario M, Mirda D, Williams LT. 1992 Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis. Nature 358: 678–681
-
(1992)
Nature
, vol.358
, pp. 678-681
-
-
Peters, K.G.1
Marie, J.2
Wilson, E.3
Ives, H.E.4
Escobedo, J.5
Del Rosario, M.6
Mirda, D.7
Williams, L.T.8
-
165
-
-
33646567190
-
Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism
-
Pitteloud N, Acierno JS Jr, Meysing A, Eliseenkova AV, Ma J, Ibrahimi OA, Metzger DL, Hayes FJ, Dwyer AA, Hughes VA, et al. 2006 Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proc Natl Acad Sci 103: 6281–6286
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 6281-6286
-
-
Pitteloud, N.1
Acierno, J.S.2
Meysing, A.3
Eliseenkova, A.V.4
Ma, J.5
Ibrahimi, O.A.6
Metzger, D.L.7
Hayes, F.J.8
Dwyer, A.A.9
Hughes, V.A.10
-
166
-
-
58149118293
-
Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst
-
Plusa B, Piliszek A, Frankenberg S, Artus J, Hadjantonakis AK. 2008 Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. Development 135: 3081–3091
-
(2008)
Development
, vol.135
, pp. 3081-3091
-
-
Plusa, B.1
Piliszek, A.2
Frankenberg, S.3
Artus, J.4
Hadjantonakis, A.K.5
-
167
-
-
0032483520
-
Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity
-
Pye DA, Vives RR, Turnbull JE, Hyde P, Gallagher JT. 1998 Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity. J Biol Chem 273: 22936–22942
-
(1998)
J Biol Chem
, vol.273
, pp. 22936-22942
-
-
Pye, D.A.1
Vives, R.R.2
Turnbull, J.E.3
Hyde, P.4
Gallagher, J.T.5
-
168
-
-
79954602896
-
Lacrimal gland development and Fgf10–Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate
-
Qu X, Carbe C, Tao C, Powers A, Lawrence R, van Kuppevelt TH, Cardoso WV, Grobe K, Esko JD, Zhang X. 2011 Lacrimal gland development and Fgf10–Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate. J Biol Chem 286: 14435–14444
-
(2011)
J Biol Chem
, vol.286
, pp. 14435-14444
-
-
Qu, X.1
Carbe, C.2
Tao, C.3
Powers, A.4
Lawrence, R.5
Van Kuppevelt, T.H.6
Cardoso, W.V.7
Grobe, K.8
Esko, J.D.9
Zhang, X.10
-
169
-
-
84866792640
-
Glycosaminoglycan- dependent restriction of FGF diffusion is necessary for lacrimal gland development
-
Qu X, Pan Y, Carbe C, Powers A, Grobe K, Zhang X. 2012 Glycosaminoglycan- dependent restriction of FGF diffusion is necessary for lacrimal gland development. Development 139: 2730–2739
-
(2012)
Development
, vol.139
, pp. 2730-2739
-
-
Qu, X.1
Pan, Y.2
Carbe, C.3
Powers, A.4
Grobe, K.5
Zhang, X.6
-
170
-
-
0027395119
-
SNT, a differentiationspecific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells
-
Rabin SJ, Cleghon V, Kaplan DR. 1993 SNT, a differentiationspecific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells. Mol Cell Biol 13: 2203–2213
-
(1993)
Mol Cell Biol
, vol.13
, pp. 2203-2213
-
-
Rabin, S.J.1
Cleghon, V.2
Kaplan, D.R.3
-
171
-
-
0033594971
-
Comparison of the intracellular signaling responses by three chimeric fibroblast growth factor receptors in PC12 cells
-
Raffioni S, Thomas D, Foehr ED, Thompson LM, Bradshaw RA. 1999 Comparison of the intracellular signaling responses by three chimeric fibroblast growth factor receptors in PC12 cells. Proc Natl Acad Sci 96: 7178–7183
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 7178-7183
-
-
Raffioni, S.1
Thomas, D.2
Foehr, E.D.3
Thompson, L.M.4
Bradshaw, R.A.5
-
172
-
-
0347717892
-
Activation of the ERK1/2 and p38 mitogen-activated protein kinase pathways mediates fibroblast growth factor-induced growth arrest of chondrocytes
-
Raucci A, Laplantine E, Mansukhani A, Basilico C. 2004 Activation of the ERK1/2 and p38 mitogen-activated protein kinase pathways mediates fibroblast growth factor-induced growth arrest of chondrocytes. J Biol Chem 279: 1747–1756
-
(2004)
J Biol Chem
, vol.279
, pp. 1747-1756
-
-
Raucci, A.1
Laplantine, E.2
Mansukhani, A.3
Basilico, C.4
-
173
-
-
0034677773
-
Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner
-
Reilly JF, Mickey G, Maher PA. 2000 Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner. J Biol Chem 275: 7771–7778
-
(2000)
J Biol Chem
, vol.275
, pp. 7771-7778
-
-
Reilly, J.F.1
Mickey, G.2
Maher, P.A.3
-
174
-
-
23944508588
-
The PI3K/Akt pathway is present and functional in the preimplantation mouse embryo
-
Riley JK, Carayannopoulos MO, Wyman AH, Chi M, Ratajczak CK, Moley KH. 2005 The PI3K/Akt pathway is present and functional in the preimplantation mouse embryo. Dev Biol 284: 377–386
-
(2005)
Dev Biol
, vol.284
, pp. 377-386
-
-
Riley, J.K.1
Carayannopoulos, M.O.2
Wyman, A.H.3
Chi, M.4
Ratajczak, C.K.5
Moley, K.H.6
-
175
-
-
33646823663
-
Phosphatidylinositol 3-kinase activity is critical for glucose metabolismand embryo survival in murine blastocysts
-
Riley JK, Carayannopoulos MO, Wyman AH, Chi M, Moley KH. 2006 Phosphatidylinositol 3-kinase activity is critical for glucose metabolismand embryo survival in murine blastocysts. J Biol Chem 281: 6010–6019
-
(2006)
J Biol Chem
, vol.281
, pp. 6010-6019
-
-
Riley, J.K.1
Carayannopoulos, M.O.2
Wyman, A.H.3
Chi, M.4
Moley, K.H.5
-
176
-
-
34248347081
-
Impaired FGF signaling contributes to cleft lip and palate
-
Riley BM, Mansilla MA, Ma J, Daack-Hirsch S, Maher BS, Raffensperger LM, Russo ET, Vieira AR, Dode C, Mohammadi M, et al. 2007 Impaired FGF signaling contributes to cleft lip and palate. Proc Natl Acad Sci 104: 4512–4517
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 4512-4517
-
-
Riley, B.M.1
Mansilla, M.A.2
Ma, J.3
Daack-Hirsch, S.4
Maher, B.S.5
Raffensperger, L.M.6
Russo, E.T.7
Vieira, A.R.8
Dode, C.9
Mohammadi, M.10
-
177
-
-
0028093135
-
Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia
-
Rousseau F, Bonaventure J, Legeai-Mallet L, Pelet A, Rozet JM, Maroteaux P, Le Merrer M, Munnich A. 1994 Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia. Nature 371: 252–254
-
(1994)
Nature
, vol.371
, pp. 252-254
-
-
Rousseau, F.1
Bonaventure, J.2
Legeai-Mallet, L.3
Pelet, A.4
Rozet, J.M.5
Maroteaux, P.6
Le Merrer, M.7
Munnich, A.8
-
178
-
-
0242607637
-
An essential function of the mitogen- activated protein kinase Erk2 in mouse trophoblast development
-
Saba-El-Leil MK, Vella FD, Vernay B, Voisin L, Chen L, Labrecque N, Ang SL, Meloche S. 2003 An essential function of the mitogen- activated protein kinase Erk2 in mouse trophoblast development. EMBO Rep 4: 964–968
-
(2003)
EMBO Rep
, vol.4
, pp. 964-968
-
-
Saba-El-Leil, M.K.1
Vella, F.D.2
Vernay, B.3
Voisin, L.4
Chen, L.5
Labrecque, N.6
Ang, S.L.7
Meloche, S.8
-
179
-
-
0033151612
-
FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
-
Sahni M, Ambrosetti DC, Mansukhani A, Gertner R, Levy D, Basilico C. 1999 FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway. Genes Dev 13: 1361–1366
-
(1999)
Genes Dev
, vol.13
, pp. 1361-1366
-
-
Sahni, M.1
Ambrosetti, D.C.2
Mansukhani, A.3
Gertner, R.4
Levy, D.5
Basilico, C.6
-
180
-
-
0034960254
-
STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2
-
Sahni M, Raz R, Coffin JD, Levy D, Basilico C. 2001 STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2. Development 128: 2119–2129
-
(2001)
Development
, vol.128
, pp. 2119-2129
-
-
Sahni, M.1
Raz, R.2
Coffin, J.D.3
Levy, D.4
Basilico, C.5
-
181
-
-
65549164714
-
A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: Activation-dependent regulation of ERK by p85 in multiple myeloma cells
-
Salazar L, Kashiwada T, Krejci P, Muchowski P, Donoghue D, Wilcox WR, Thompson LM. 2009 A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells. Hum Mol Genet 18: 1951–1961
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1951-1961
-
-
Salazar, L.1
Kashiwada, T.2
Krejci, P.3
Muchowski, P.4
Donoghue, D.5
Wilcox, W.R.6
Thompson, L.M.7
-
182
-
-
0034919848
-
Inductive signal and tissue responsiveness defining the tectum and the cerebellum
-
Sato T, Araki I, Nakamura H. 2001 Inductive signal and tissue responsiveness defining the tectum and the cerebellum. Development 128: 2461–2469
-
(2001)
Development
, vol.128
, pp. 2461-2469
-
-
Sato, T.1
Araki, I.2
Nakamura, H.3
-
183
-
-
0035214904
-
Fgf/MAPK signalling is a crucial positional cue in somite boundary formation
-
Sawada A, Shinya M, Jiang YJ, Kawakami A, Kuroiwa A, Takeda H. 2001 Fgf/MAPK signalling is a crucial positional cue in somite boundary formation. Development 128: 4873–4880
-
(2001)
Development
, vol.128
, pp. 4873-4880
-
-
Sawada, A.1
Shinya, M.2
Jiang, Y.J.3
Kawakami, A.4
Kuroiwa, A.5
Takeda, H.6
-
184
-
-
0030921502
-
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2
-
Saxton TM, Henkemeyer M, Gasca S, Shen R, Rossi DJ, Shalaby F, Feng GS, Pawson T. 1997 Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2. EMBO J 16: 2352–2364
-
(1997)
EMBO J
, vol.16
, pp. 2352-2364
-
-
Saxton, T.M.1
Henkemeyer, M.2
Gasca, S.3
Shen, R.4
Rossi, D.J.5
Shalaby, F.6
Feng, G.S.7
Pawson, T.8
-
185
-
-
82355188226
-
Plasma FGF21 is elevated by the intense lipid mobilization of lactation
-
Schoenberg KM, Giesy SL, Harvatine KJ, Waldron MR, Cheng C, Kharitonenkov A, Boisclair YR. 2011 Plasma FGF21 is elevated by the intense lipid mobilization of lactation. Endocrinology 152: 4652–4661
-
(2011)
Endocrinology
, vol.152
, pp. 4652-4661
-
-
Schoenberg, K.M.1
Giesy, S.L.2
Harvatine, K.J.3
Waldron, M.R.4
Cheng, C.5
Kharitonenkov, A.6
Boisclair, Y.R.7
-
186
-
-
0028174023
-
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
-
Schuchardt A, D’Agati V, Larsson-Blomberg L, Costantini F, Pachnis V. 1994 Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367: 380–383
-
(1994)
Nature
, vol.367
, pp. 380-383
-
-
Schuchardt, A.1
D’Agati, V.2
Larsson-Blomberg, L.3
Costantini, F.4
Pachnis, V.5
-
187
-
-
58149289662
-
Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2)
-
Schuller AC, Ahmed Z, Levitt JA, Suen KM, Suhling K, Ladbury JE. 2008 Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2). Biochem J 416: 189–199
-
(2008)
Biochem J
, vol.416
, pp. 189-199
-
-
Schuller, A.C.1
Ahmed, Z.2
Levitt, J.A.3
Suen, K.M.4
Suhling, K.5
Ladbury, J.E.6
-
188
-
-
79251537178
-
Genetic inactivation of ERK1 and ERK2 in chondrocytes promotes bone growth and enlarges the spinal canal
-
Sebastian A, Matsushita T, Kawanami A, Mackem S, Landreth GE, Murakami S. 2011 Genetic inactivation of ERK1 and ERK2 in chondrocytes promotes bone growth and enlarges the spinal canal. J Orthop Res 29: 375–379
-
(2011)
J Orthop Res
, vol.29
, pp. 375-379
-
-
Sebastian, A.1
Matsushita, T.2
Kawanami, A.3
Mackem, S.4
Landreth, G.E.5
Murakami, S.6
-
189
-
-
66349106792
-
Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop
-
Seo JH, Suenaga A, Hatakeyama M, Taiji M, Imamoto A. 2009 Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop. Mol Cell Biol 29: 3076–3087
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3076-3087
-
-
Seo, J.H.1
Suenaga, A.2
Hatakeyama, M.3
Taiji, M.4
Imamoto, A.5
-
190
-
-
0029062582
-
Fibroblast growth factor receptors display both common and distinct signaling pathways
-
Shaoul E, Reich-Slotky R, Berman B, Ron D. 1995 Fibroblast growth factor receptors display both common and distinct signaling pathways. Oncogene 10: 1553–1561
-
(1995)
Oncogene
, vol.10
, pp. 1553-1561
-
-
Shaoul, E.1
Reich-Slotky, R.2
Berman, B.3
Ron, D.4
-
191
-
-
0027964261
-
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
-
Shiang R, Thompson LM, Zhu YZ, Church DM, Fielder TJ, Bocian M, Winokur ST, Wasmuth JJ. 1994 Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell 78: 335–342
-
(1994)
Cell
, vol.78
, pp. 335-342
-
-
Shiang, R.1
Thompson, L.M.2
Zhu, Y.Z.3
Church, D.M.4
Fielder, T.J.5
Bocian, M.6
Winokur, S.T.7
Wasmuth, J.J.8
-
192
-
-
1642416884
-
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism
-
Shimada T, Kakitani M, Yamazaki Y, Hasegawa H, Takeuchi Y, Fujita T, Fukumoto S, Tomizuka K, Yamashita T. 2004 Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest 113: 561–568
-
(2004)
J Clin Invest
, vol.113
, pp. 561-568
-
-
Shimada, T.1
Kakitani, M.2
Yamazaki, Y.3
Hasegawa, H.4
Takeuchi, Y.5
Fujita, T.6
Fukumoto, S.7
Tomizuka, K.8
Yamashita, T.9
-
193
-
-
0036510743
-
Regulation of osteoblast, chondrocyte, and osteoclast functions by fibroblast growth factor (FGF)-18 in comparison with FGF-2 and FGF- 10
-
Shimoaka T, Ogasawara T, Yonamine A, Chikazu D, Kawano H, Nakamura K, Itoh N, Kawaguchi H. 2002 Regulation of osteoblast, chondrocyte, and osteoclast functions by fibroblast growth factor (FGF)-18 in comparison with FGF-2 and FGF- 10. J Biol Chem 277: 7493–7500
-
(2002)
J Biol Chem
, vol.277
, pp. 7493-7500
-
-
Shimoaka, T.1
Ogasawara, T.2
Yonamine, A.3
Chikazu, D.4
Kawano, H.5
Nakamura, K.6
Itoh, N.7
Kawaguchi, H.8
-
194
-
-
79961223673
-
Cell surface heparan sulfate chains regulate local reception of FGF signaling in the mouse embryo
-
Shimokawa K, Kimura-Yoshida C, Nagai N, Mukai K, Matsubara K, Watanabe H, Matsuda Y, Mochida K, Matsuo I. 2011 Cell surface heparan sulfate chains regulate local reception of FGF signaling in the mouse embryo. Dev Cell 21: 257–272
-
(2011)
Dev Cell
, vol.21
, pp. 257-272
-
-
Shimokawa, K.1
Kimura-Yoshida, C.2
Nagai, N.3
Mukai, K.4
Matsubara, K.5
Watanabe, H.6
Matsuda, Y.7
Mochida, K.8
Matsuo, I.9
-
195
-
-
34548371795
-
RNA interference and inhibition of MEK–ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis
-
Shukla V, Coumoul X, Wang RH, Kim HS, Deng CX. 2007 RNA interference and inhibition of MEK–ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis. Nat Genet 39: 1145–1150
-
(2007)
Nat Genet
, vol.39
, pp. 1145-1150
-
-
Shukla, V.1
Coumoul, X.2
Wang, R.H.3
Kim, H.S.4
Deng, C.X.5
-
196
-
-
0029045856
-
Strain-dependent epithelial defects in mice lacking the EGF receptor
-
Sibilia M, Wagner EF. 1995 Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269: 234–238
-
(1995)
Science
, vol.269
, pp. 234-238
-
-
Sibilia, M.1
Wagner, E.F.2
-
197
-
-
84883170151
-
FGFR1 mutations cause Hartsfield syndrome, the unique association of holoprosencephaly and ectrodactyly
-
Simonis N, Migeotte I, Lambert N, Perazzolo C, de Silva DC, Dimitrov B, Heinrichs C, Janssens S, Kerr B, Mortier G, et al. 2013 FGFR1 mutations cause Hartsfield syndrome, the unique association of holoprosencephaly and ectrodactyly. J Med Genet 50: 585–592
-
(2013)
J Med Genet
, vol.50
, pp. 585-592
-
-
Simonis, N.1
Migeotte, I.2
Lambert, N.3
Perazzolo, C.4
De Silva, D.C.5
Dimitrov, B.6
Heinrichs, C.7
Janssens, S.8
Kerr, B.9
Mortier, G.10
-
198
-
-
70350712283
-
Deletion of Frs2α from the ureteric epithelium causes renal hypoplasia
-
Sims-Lucas S, Cullen-McEwen L, Eswarakumar VP, Hains D, Kish K, Becknell B, Zhang J, Bertram JF, Wang F, Bates CM. 2009 Deletion of Frs2α from the ureteric epithelium causes renal hypoplasia. Am J Physiol Renal Physiol 297: F1208–F1219
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F1208-F1219
-
-
Sims-Lucas, S.1
Cullen-McEwen, L.2
Eswarakumar, V.P.3
Hains, D.4
Kish, K.5
Becknell, B.6
Zhang, J.7
Bertram, J.F.8
Wang, F.9
Bates, C.M.10
-
199
-
-
0029820043
-
Fibroblast growth factor (FGF) homologous factors: New members of the FGF family implicated in nervous system development
-
Smallwood PM, Munoz-Sanjuan I, Tong P, Macke JP, Hendry SH, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J. 1996 Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci 93: 9850–9857
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 9850-9857
-
-
Smallwood, P.M.1
Munoz-Sanjuan, I.2
Tong, P.3
Macke, J.P.4
Hendry, S.H.5
Gilbert, D.J.6
Copeland, N.G.7
Jenkins, N.A.8
Nathans, J.9
-
200
-
-
0028356454
-
Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766
-
Sorokin A, Mohammadi M, Huang J, Schlessinger J. 1994 Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766. J Biol Chem 269: 17056–17061
-
(1994)
J Biol Chem
, vol.269
, pp. 17056-17061
-
-
Sorokin, A.1
Mohammadi, M.2
Huang, J.3
Schlessinger, J.4
-
201
-
-
84866439571
-
Development of the lip and palate: FGF signalling
-
Stanier P, Pauws E. 2012 Development of the lip and palate: FGF signalling. Front Oral Biol 16: 71–80
-
(2012)
Front Oral Biol
, vol.16
, pp. 71-80
-
-
Stanier, P.1
Pauws, E.2
-
202
-
-
17244378089
-
FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis
-
Steinberg Z, Myers C, Heim VM, Lathrop CA, Rebustini IT, Stewart JS, Larsen M, Hoffman MP. 2005 FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis. Development 132: 1223–1234
-
(2005)
Development
, vol.132
, pp. 1223-1234
-
-
Steinberg, Z.1
Myers, C.2
Heim, V.M.3
Lathrop, C.A.4
Rebustini, I.T.5
Stewart, J.S.6
Larsen, M.7
Hoffman, M.P.8
-
203
-
-
0017979060
-
Cutis gyratum and acanthosis nigricans associated with other anomalies: A distinctive syndrome
-
Stevenson RE, Ferlauto GJ, Taylor HA. 1978 Cutis gyratum and acanthosis nigricans associated with other anomalies: a distinctive syndrome. J Pediatr 92: 950–952
-
(1978)
J Pediatr
, vol.92
, pp. 950-952
-
-
Stevenson, R.E.1
Ferlauto, G.J.2
Taylor, H.A.3
-
204
-
-
0034103657
-
Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development
-
Sun X, Lewandoski M, Meyers EN, Liu YH, Maxson RE Jr, Martin GR. 2000 Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development. Nat Genet 25: 83–86
-
(2000)
Nat Genet
, vol.25
, pp. 83-86
-
-
Sun, X.1
Lewandoski, M.2
Meyers, E.N.3
Liu, Y.H.4
Maxson, R.E.5
Martin, G.R.6
-
205
-
-
0036682468
-
Functions of FGF signalling fromthe apical ectodermal ridge in limb development
-
Sun X, Mariani FV, Martin GR. 2002 Functions of FGF signalling fromthe apical ectodermal ridge in limb development. Nature 418: 501–508
-
(2002)
Nature
, vol.418
, pp. 501-508
-
-
Sun, X.1
Mariani, F.V.2
Martin, G.R.3
-
206
-
-
0034671968
-
Retention of PDGFR-β function in mice in the absence of phosphatidylinositol 3′-kinase and phospholipase Cγ signaling pathways
-
Tallquist MD, Klinghoffer RA, Heuchel R, Mueting-Nelsen PF, Corrin PD, Heldin CH, Johnson RJ, Soriano P. 2000 Retention of PDGFR-β function in mice in the absence of phosphatidylinositol 3′-kinase and phospholipase Cγ signaling pathways. Genes Dev 14: 3179–3190
-
(2000)
Genes Dev
, vol.14
, pp. 3179-3190
-
-
Tallquist, M.D.1
Klinghoffer, R.A.2
Heuchel, R.3
Mueting-Nelsen, P.F.4
Corrin, P.D.5
Heldin, C.H.6
Johnson, R.J.7
Soriano, P.8
-
207
-
-
2342419356
-
Additive effects of PDGF receptor β signaling pathways in vascular smooth muscle cell development
-
Tallquist MD, French WJ, Soriano P. 2003 Additive effects of PDGF receptor β signaling pathways in vascular smooth muscle cell development. PLoS Biol 1: E52
-
(2003)
Plos Biol
, vol.1
-
-
Tallquist, M.D.1
French, W.J.2
Soriano, P.3
-
208
-
-
0029790656
-
FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2
-
Tan Y, Rouse J, Zhang A, Cariati S, Cohen P, Comb MJ. 1996 FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2. EMBO J 15: 4629–4642
-
(1996)
EMBO J
, vol.15
, pp. 4629-4642
-
-
Tan, Y.1
Rouse, J.2
Zhang, A.3
Cariati, S.4
Cohen, P.5
Comb, M.J.6
-
209
-
-
77953478023
-
Distinct FGFs promote differentiation of excitatory and inhibitory synapses
-
Terauchi A, Johnson-Venkatesh EM, Toth AB, Javed D, Sutton MA, Umemori H. 2010 Distinct FGFs promote differentiation of excitatory and inhibitory synapses. Nature 465: 783–787
-
(2010)
Nature
, vol.465
, pp. 783-787
-
-
Terauchi, A.1
Johnson-Venkatesh, E.M.2
Toth, A.B.3
Javed, D.4
Sutton, M.A.5
Umemori, H.6
-
210
-
-
84925545317
-
PI3K in cancer: Divergent roles of isoforms, modes of activation and therapeutic targeting
-
Thorpe LM, Yuzugullu H, Zhao JJ. 2015 PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting. Nat Rev Cancer 15: 7–24
-
(2015)
Nat Rev Cancer
, vol.15
, pp. 7-24
-
-
Thorpe, L.M.1
Yuzugullu, H.2
Zhao, J.J.3
-
211
-
-
0029064203
-
Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype
-
Threadgill DW, Dlugosz AA, Hansen LA, Tennenbaum T, Lichti U, Yee D, LaMantia C, Mourton T, Herrup K, Harris RC, et al. 1995 Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science 269: 230–234
-
(1995)
Science
, vol.269
, pp. 230-234
-
-
Threadgill, D.W.1
Dlugosz, A.A.2
Hansen, L.A.3
Tennenbaum, T.4
Lichti, U.5
Yee, D.6
Lamantia, C.7
Mourton, T.8
Herrup, K.9
Harris, R.C.10
-
212
-
-
84893769451
-
Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion
-
Timsah Z, Ahmed Z, Lin CC, Melo FA, Stagg LJ, Leonard PG, Jeyabal P, Berrout J, O’Neil RG, Bogdanov M, et al. 2014 Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion. Nat Struct Mol Biol 21: 180–188
-
(2014)
Nat Struct Mol Biol
, vol.21
, pp. 180-188
-
-
Timsah, Z.1
Ahmed, Z.2
Lin, C.C.3
Melo, F.A.4
Stagg, L.J.5
Leonard, P.G.6
Jeyabal, P.7
Berrout, J.8
O’Neil, R.G.9
Bogdanov, M.10
-
214
-
-
84879604942
-
Role of FGFRL1 and other FGF signaling proteins in early kidney development
-
Trueb B, Amann R, Gerber SD. 2013 Role of FGFRL1 and other FGF signaling proteins in early kidney development. Cell Mol Life Sci 70: 2505–2518
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 2505-2518
-
-
Trueb, B.1
Amann, R.2
Gerber, S.D.3
-
215
-
-
0033397681
-
Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch
-
Trumpp A, Depew MJ, Rubenstein JL, Bishop JM, Martin GR. 1999 Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes Dev 13: 3136–3148
-
(1999)
Genes Dev
, vol.13
, pp. 3136-3148
-
-
Trumpp, A.1
Depew, M.J.2
Rubenstein, J.L.3
Bishop, J.M.4
Martin, G.R.5
-
216
-
-
11244325104
-
Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population
-
Tsai PS, Moenter SM, Postigo HR, El Majdoubi M, Pak TR, Gill JC, Paruthiyil S, Werner S, Weiner RI. 2005 Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population. Mol Endocrinol (Baltimore, Md) 19: 225–236
-
(2005)
Mol Endocrinol (Baltimore, Md
, vol.19
, pp. 225-236
-
-
Tsai, P.S.1
Moenter, S.M.2
Postigo, H.R.3
El Majdoubi, M.4
Pak, T.R.5
Gill, J.C.6
Paruthiyil, S.7
Werner, S.8
Weiner, R.I.9
-
217
-
-
33845802651
-
Noncanonical Wnt signaling through G protein-linked PKCδ activation promotes bone formation
-
Tu X, Joeng KS, Nakayama KI, Nakayama K, Rajagopal J, Carroll TJ, McMahon AP, Long F. 2007 Noncanonical Wnt signaling through G protein-linked PKCδ activation promotes bone formation. Dev Cell 12: 113–127
-
(2007)
Dev Cell
, vol.12
, pp. 113-127
-
-
Tu, X.1
Joeng, K.S.2
Nakayama, K.I.3
Nakayama, K.4
Rajagopal, J.5
Carroll, T.J.6
McMahon, A.P.7
Long, F.8
-
218
-
-
77956682916
-
Extending the family table: Insights from beyond vertebrates into the regulation of embryonic development by FGFs
-
Tulin S, Stathopoulos A. 2010 Extending the family table: insights from beyond vertebrates into the regulation of embryonic development by FGFs. Birth Defects Res C Embryo Today 90: 214–227
-
(2010)
Birth Defects Res C Embryo Today
, vol.90
, pp. 214-227
-
-
Tulin, S.1
Stathopoulos, A.2
-
219
-
-
0026541181
-
Atruncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor
-
Ueno H, Gunn M, Dell K, Tseng A Jr, Williams L. 1992.Atruncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor. J Biol Chem 267: 1470–1476
-
(1992)
J Biol Chem
, vol.267
, pp. 1470-1476
-
-
Ueno, H.1
Gunn, M.2
Dell, K.3
Tseng, A.4
Williams, L.5
-
220
-
-
84951320585
-
Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site
-
Ulaganathan VK, Sperl B, Rapp UR, Ullrich A. 2015 Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site. Nature 528: 570–574
-
(2015)
Nature
, vol.528
, pp. 570-574
-
-
Ulaganathan, V.K.1
Sperl, B.2
Rapp, U.R.3
Ullrich, A.4
-
221
-
-
33845631059
-
Klotho converts canonical FGF receptor into a specific receptor for FGF23
-
Urakawa I, Yamazaki Y, Shimada T, Iijima K, Hasegawa H, Okawa K, Fujita T, Fukumoto S, Yamashita T. 2006 Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 444: 770–774
-
(2006)
Nature
, vol.444
, pp. 770-774
-
-
Urakawa, I.1
Yamazaki, Y.2
Shimada, T.3
Iijima, K.4
Hasegawa, H.5
Okawa, K.6
Fujita, T.7
Fukumoto, S.8
Yamashita, T.9
-
222
-
-
0028332812
-
Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1
-
Vainikka S, Joukov V, Wennstrom S, Bergman M, Pelicci PG, Alitalo K. 1994 Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1. J Biol Chem 269: 18320–18326
-
(1994)
J Biol Chem
, vol.269
, pp. 18320-18326
-
-
Vainikka, S.1
Joukov, V.2
Wennstrom, S.3
Bergman, M.4
Pelicci, P.G.5
Alitalo, K.6
-
223
-
-
0030033411
-
Association of a 85- kDa serine kinase with activated fibroblast growth factor receptor-4
-
Vainikka S, Joukov V, Klint P, Alitalo K. 1996 Association of a 85- kDa serine kinase with activated fibroblast growth factor receptor-4. J Biol Chem 271: 1270–1273
-
(1996)
J Biol Chem
, vol.271
, pp. 1270-1273
-
-
Vainikka, S.1
Joukov, V.2
Klint, P.3
Alitalo, K.4
-
224
-
-
84930619544
-
Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways
-
Vasudevan HN, Mazot P, He F, Soriano P. 2015 Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways. Elife 4: e07186
-
(2015)
Elife
, vol.4
-
-
Vasudevan, H.N.1
Mazot, P.2
He, F.3
Soriano, P.4
-
225
-
-
37249044796
-
FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis
-
Wahl MB, Deng C, Lewandoski M, Pourquie O. 2007 FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development 134: 4033–4041
-
(2007)
Development
, vol.134
, pp. 4033-4041
-
-
Wahl, M.B.1
Deng, C.2
Lewandoski, M.3
Pourquie, O.4
-
226
-
-
0027955135
-
Fibroblast growth factor receptors have different signaling and mitogenic potentials
-
Wang JK, Gao G, Goldfarb M. 1994 Fibroblast growth factor receptors have different signaling and mitogenic potentials. Mol Cell Biol 14: 181–188
-
(1994)
Mol Cell Biol
, vol.14
, pp. 181-188
-
-
Wang, J.K.1
Gao, G.2
Goldfarb, M.3
-
227
-
-
13044278311
-
A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3
-
Wang Y, Spatz MK, Kannan K, Hayk H, Avivi A, Gorivodsky M, Pines M, Yayon A, Lonai P, Givol D. 1999 A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3. Proc Natl Acad Sci 96: 4455–4460
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 4455-4460
-
-
Wang, Y.1
Spatz, M.K.2
Kannan, K.3
Hayk, H.4
Avivi, A.5
Gorivodsky, M.6
Pines, M.7
Yayon, A.8
Lonai, P.9
Givol, D.10
-
228
-
-
24344453489
-
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse
-
Wang Y, Xiao R, Yang F, Karim BO, Iacovelli AJ, Cai J, Lerner CP, Richtsmeier JT, Leszl JM, Hill CA, et al. 2005 Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development 132: 3537–3548
-
(2005)
Development
, vol.132
, pp. 3537-3548
-
-
Wang, Y.1
Xiao, R.2
Yang, F.3
Karim, B.O.4
Iacovelli, A.J.5
Cai, J.6
Lerner, C.P.7
Richtsmeier, J.T.8
Leszl, J.M.9
Hill, C.A.10
-
229
-
-
84861801246
-
p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice
-
Wang Y, Zhou X, Oberoi K, Phelps R, Couwenhoven R, Sun M, Rezza A, Holmes G, Percival CJ, Friedenthal J, et al. 2012. p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice. J Clin Invest 122: 2153–2164
-
(2012)
J Clin Invest
, vol.122
, pp. 2153-2164
-
-
Wang, Y.1
Zhou, X.2
Oberoi, K.3
Phelps, R.4
Couwenhoven, R.5
Sun, M.6
Rezza, A.7
Holmes, G.8
Percival, C.J.9
Friedenthal, J.10
-
230
-
-
84881222338
-
Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis
-
Wang C, Chang JY, Yang C, Huang Y, Liu J, You P, McKeehan WL, Wang F, Li X. 2013 Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis. J Biol Chem 288: 22174–22183
-
(2013)
J Biol Chem
, vol.288
, pp. 22174-22183
-
-
Wang, C.1
Chang, J.Y.2
Yang, C.3
Huang, Y.4
Liu, J.5
You, P.6
McKeehan, W.L.7
Wang, F.8
Li, X.9
-
231
-
-
61649087689
-
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
-
Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP. 2009 ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell 33: 591–601
-
(2009)
Mol Cell
, vol.33
, pp. 591-601
-
-
Warzecha, C.C.1
Sato, T.K.2
Nabet, B.3
Hogenesch, J.B.4
Carstens, R.P.5
-
232
-
-
0031700905
-
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
-
Weinstein M, Xu X, Ohyama K, Deng CX. 1998 FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125: 3615–3623
-
(1998)
Development
, vol.125
, pp. 3615-3623
-
-
Weinstein, M.1
Xu, X.2
Ohyama, K.3
Deng, C.X.4
-
233
-
-
33646705916
-
FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains
-
White AC, Xu J, Yin Y, Smith C, Schmid G, Ornitz DM. 2006 FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains. Development 133: 1507–1517
-
(2006)
Development
, vol.133
, pp. 1507-1517
-
-
White, A.C.1
Xu, J.2
Yin, Y.3
Smith, C.4
Schmid, G.5
Ornitz, D.M.6
-
234
-
-
84862753735
-
Extracellular signal-regulated kinase 1 and 2 are not required for GnRH neuron development and normal female reproductive axis function in mice
-
Wierman ME, Xu M, Pierce A, Bliesner B, Bliss SP, Roberson MS. 2012 Extracellular signal-regulated kinase 1 and 2 are not required for GnRH neuron development and normal female reproductive axis function in mice. Neuroendocrinology 95: 289–296
-
(2012)
Neuroendocrinology
, vol.95
, pp. 289-296
-
-
Wierman, M.E.1
Xu, M.2
Pierce, A.3
Bliesner, B.4
Bliss, S.P.5
Roberson, M.S.6
-
235
-
-
0028798546
-
Apert syndrome results from localized mutationsof FGFR2 and is allelic with Crouzon syndrome
-
Wilkie AO, Slaney SF, Oldridge M, Poole MD, Ashworth GJ, Hockley AD, Hayward RD, David DJ, Pulleyn LJ, Rutland P, et al. 1995 Apert syndrome results from localized mutationsof FGFR2 and is allelic with Crouzon syndrome. Nat Genet 9: 165–172
-
(1995)
Nat Genet
, vol.9
, pp. 165-172
-
-
Wilkie, A.O.1
Slaney, S.F.2
Oldridge, M.3
Poole, M.D.4
Ashworth, G.J.5
Hockley, A.D.6
Hayward, R.D.7
David, D.J.8
Pulleyn, L.J.9
Rutland, P.10
-
236
-
-
0032540941
-
Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins
-
Xu H, Lee KW, Goldfarb M. 1998a. Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins. J Biol Chem 273: 17987–17990
-
(1998)
J Biol Chem
, vol.273
, pp. 17987-17990
-
-
Xu, H.1
Lee, K.W.2
Goldfarb, M.3
-
237
-
-
0031885801
-
Fibroblast growth factor receptor 2 (FGFR2)- mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
-
Xu X, Weinstein M, Li C, Naski M, Cohen RI, Ornitz DM, Leder P, Deng C. 1998b. Fibroblast growth factor receptor 2 (FGFR2)- mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development 125: 753–765
-
(1998)
Development
, vol.125
, pp. 753-765
-
-
Xu, X.1
Weinstein, M.2
Li, C.3
Naski, M.4
Cohen, R.I.5
Ornitz, D.M.6
Leder, P.7
Deng, C.8
-
238
-
-
0028582035
-
Fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation
-
Yamaguchi TP, Harpal K, Henkemeyer M, Rossant J. 1994. fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev 8: 3032–3044
-
(1994)
Genes Dev
, vol.8
, pp. 3032-3044
-
-
Yamaguchi, T.P.1
Harpal, K.2
Henkemeyer, M.3
Rossant, J.4
-
239
-
-
76449083746
-
FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst
-
Yamanaka Y, Lanner F, Rossant J. 2010 FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst. Development 137: 715–724
-
(2010)
Development
, vol.137
, pp. 715-724
-
-
Yamanaka, Y.1
Lanner, F.2
Rossant, J.3
-
240
-
-
0042357084
-
Protein kinase B α/Akt1 regulates placental development and fetal growth
-
Yang ZZ, Tschopp O, Hemmings-Mieszczak M, Feng J, Brodbeck D, Perentes E, Hemmings BA. 2003 Protein kinase B α/Akt1 regulates placental development and fetal growth. J Biol Chem 278: 32124–32131
-
(2003)
J Biol Chem
, vol.278
, pp. 32124-32131
-
-
Yang, Z.Z.1
Tschopp, O.2
Hemmings-Mieszczak, M.3
Feng, J.4
Brodbeck, D.5
Perentes, E.6
Hemmings, B.A.7
-
241
-
-
27944493875
-
Dosage-dependent effects of Akt1/protein kinase Bα (PKBα) and Akt3/PKBγ on thymus, skin, and cardiovascular and nervous system development in mice
-
Yang ZZ, Tschopp O, Di-Poi N, Bruder E, Baudry A, Dummler B, Wahli W, Hemmings BA. 2005 Dosage-dependent effects of Akt1/protein kinase Bα (PKBα) and Akt3/PKBγ on thymus, skin, and cardiovascular and nervous system development in mice. Mol Cell Biol 25: 10407–10418
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10407-10418
-
-
Yang, Z.Z.1
Tschopp, O.2
Di-Poi, N.3
Bruder, E.4
Baudry, A.5
Dummler, B.6
Wahli, W.7
Hemmings, B.A.8
-
242
-
-
60549091399
-
Signal transducers and activators of transcription mediate fibroblast growth factor-induced vascular endothelial morphogenesis
-
Yang X, Qiao D, Meyer K, Friedl A. 2009 Signal transducers and activators of transcription mediate fibroblast growth factor-induced vascular endothelial morphogenesis. Cancer Res 69: 1668–1677
-
(2009)
Cancer Res
, vol.69
, pp. 1668-1677
-
-
Yang, X.1
Qiao, D.2
Meyer, K.3
Friedl, A.4
-
243
-
-
21244473773
-
Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform
-
Yaylaoglu MB, Titmus A, Visel A, Alvarez-Bolado G, Thaller C, Eichele G. 2005 Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform. Dev Dyn 234: 371–386
-
(2005)
Dev Dyn
, vol.234
, pp. 371-386
-
-
Yaylaoglu, M.B.1
Titmus, A.2
Visel, A.3
Alvarez-Bolado, G.4
Thaller, C.5
Eichele, G.6
-
244
-
-
40949140612
-
A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis
-
Yin L, Du X, Li C, Xu X, Chen Z, Su N, Zhao L, Qi H, Li F, Xue J, et al. 2008 A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis. Bone 42: 631–643
-
(2008)
Bone
, vol.42
, pp. 631-643
-
-
Yin, L.1
Du, X.2
Li, C.3
Xu, X.4
Chen, Z.5
Su, N.6
Zhao, L.7
Qi, H.8
Li, F.9
Xue, J.10
-
245
-
-
41649095548
-
FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis
-
Yu K, Ornitz DM. 2008 FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis. Development 135: 483–491
-
(2008)
Development
, vol.135
, pp. 483-491
-
-
Yu, K.1
Ornitz, D.M.2
-
246
-
-
0034685916
-
Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4
-
Yu C, Wang F, Kan M, Jin C, Jones RB, Weinstein M, Deng CX, McKeehan WL. 2000 Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4. J Biol Chem 275: 15482–15489
-
(2000)
J Biol Chem
, vol.275
, pp. 15482-15489
-
-
Yu, C.1
Wang, F.2
Kan, M.3
Jin, C.4
Jones, R.B.5
Weinstein, M.6
Deng, C.X.7
McKeehan, W.L.8
-
247
-
-
0038782306
-
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
-
Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, Towler DA, Ornitz DM. 2003 Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130: 3063–3074
-
(2003)
Development
, vol.130
, pp. 3063-3074
-
-
Yu, K.1
Xu, J.2
Liu, Z.3
Sosic, D.4
Shao, J.5
Olson, E.N.6
Towler, D.A.7
Ornitz, D.M.8
-
248
-
-
23644451052
-
Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids
-
Yu C, Wang F, Jin C, Huang X, McKeehan WL. 2005 Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. J Biol Chem 280: 17707–17714
-
(2005)
J Biol Chem
, vol.280
, pp. 17707-17714
-
-
Yu, C.1
Wang, F.2
Jin, C.3
Huang, X.4
McKeehan, W.L.5
-
249
-
-
1842419436
-
Fibroblast growth factor receptor 1-IIIb is dispensable for skin morphogenesis and wound healing
-
Zhang H, Dessimoz J, Beyer TA, Krampert M, Williams LT, Werner S, Grose R. 2004 Fibroblast growth factor receptor 1-IIIb is dispensable for skin morphogenesis and wound healing. Eur J Cell Biol 83: 3–11
-
(2004)
Eur J Cell Biol
, vol.83
, pp. 3-11
-
-
Zhang, H.1
Dessimoz, J.2
Beyer, T.A.3
Krampert, M.4
Williams, L.T.5
Werner, S.6
Grose, R.7
-
250
-
-
33744937606
-
Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family
-
Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. 2006 Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem 281: 15694–15700
-
(2006)
J Biol Chem
, vol.281
, pp. 15694-15700
-
-
Zhang, X.1
Ibrahimi, O.A.2
Olsen, S.K.3
Umemori, H.4
Mohammadi, M.5
Ornitz, D.M.6
-
251
-
-
9944233235
-
Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud
-
Zhao H, Kegg H, Grady S, Truong HT, Robinson ML, Baum M, Bates CM. 2004 Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud. Dev Biol 276: 403–415.
-
(2004)
Dev Biol
, vol.276
, pp. 403-415
-
-
Zhao, H.1
Kegg, H.2
Grady, S.3
Truong, H.T.4
Robinson, M.L.5
Baum, M.6
Bates, C.M.7
|