FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 10, 2011, Pages 4018-4023

  Naiche, L A ^a   Holder, Nakisha ^a,b   Lewandoski, Mark ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Axis extension; Genetic redundancy; Paraxial mesoderm; Spry; T Cre

Indexed keywords

FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 8; WNT PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE DELETION; GENE EXPRESSION; MESODERM; MOUSE; NONHUMAN; PRESOMITIC MESODERM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOMITE; SOMITOGENESIS;

ANIMALS; EMBRYONIC DEVELOPMENT; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 8; MICE; SIGNAL TRANSDUCTION; SOMITES;

EID: 79951680614     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1007417108     Document Type: Article

References (47)

1. Dubrulle J, Pourquié O (2004) Coupling segmentation to axis formation. Development 131:5783-5793. (Pubitemid 40123896)
2. Turnpenny PD, et al. (2007) Abnormal vertebral segmentation and the Notch signaling pathway in man. Dev Dyn 236:1456-1474. (Pubitemid 46932351)
3. Cooke J, Zeeman EC (1976) A clock and wavefront model for control of the number of repeated structures during animal morphogenesis. J Theor Biol 58:455-476.
4. Sawada A, et al. (2001) Fgf/MAPK signalling is a crucial positional cue in somite boundary formation. Development 128:4873-4880. (Pubitemid 33138596)
5. Dubrulle J, McGrew MJ, Pourquié O (2001) FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Cell 106:219-232. (Pubitemid 32772632)
6. Delfini MC, Dubrulle J, Malapert P, Chal J, Pourquié O (2005) Control of the segmentation process by graded MAPK/ERK activation in the chick embryo. Proc Natl Acad Sci USA 102:11343-11348. (Pubitemid 41153822)
7. Perantoni AO, et al. (2005) Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development 132:3859-3871. (Pubitemid 41410251)
8. Sun X, Meyers EN, Lewandoski M, Martin GR (1999) Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev 13:1834-1846. (Pubitemid 29353050)
9. Itoh N, Ornitz DM (2008) Functional evolutionary history of the mouse Fgf gene family. Dev Dyn 237:18-27.
10. Yamaguchi TP, Conlon RA, Rossant J (1992) Expression of the fibroblast growth factor receptor FGFR-1/flg during gastrulation and segmentation in the mouse embryo. Dev Biol 152:75-88.
11. Wahl MB, Deng C, Lewandoski M, Pourquié O (2007) FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development 134:4033-4041. (Pubitemid 350269420)
12. Oginuma M, Niwa Y, Chapman DL, Saga Y (2008) Mesp2 and Tbx6 cooperatively create periodic patterns coupled with the clock machinery during mouse somitogenesis. Development 135:2555-2562.
13. Aulehla A, et al. (2008) A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Nat Cell Biol 10:186-193. (Pubitemid 351194048)
14. Dequéant ML, Pourquié O (2008) Segmental patterning of the vertebrate embryonic axis. Nat Rev Genet 9:370-382.
15. Aulehla A, et al. (2003) Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell 4:395-406. (Pubitemid 36342364)
16. Dunty WC, Jr., et al. (2008) Wnt3a/β-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development 135:85-94.
17. Sun X, et al. (2000) Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development. Nat Genet 25:83-86. (Pubitemid 30257042)
18. Turner N, Grose R (2010) Fibroblast growth factor signalling: From development to cancer. Nat Rev Cancer 10:116-129.
19. Downs KM, Davies T (1993) Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development 118:1255-1266. (Pubitemid 23252413)
20. Goldbeter A, Gonze D, Pourquié O (2007) Sharp developmental thresholds defined through bistability by antagonistic gradients of retinoic acid and FGF signaling. Dev Dyn 236:1495-1508. (Pubitemid 46932354)
21. Cole SE, Levorse JM, Tilghman SM, Vogt TF (2002) Clock regulatory elements control cyclic expression of Lunatic fringe during somitogenesis. Dev Cell 3:75-84. (Pubitemid 34778397)
22. Vermot J, et al. (2005) Retinoic acid controls the bilateral symmetry of somite formation in the mouse embryo. Science 308:563-566. (Pubitemid 40570589)
23. Morimoto M, et al. (2007) The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite. Development 134:1561-1569. (Pubitemid 46746308)
24. Harada N, et al. (1999) Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene. EMBO J 18:5931-5942. (Pubitemid 29515670)
25. Fujimura N, et al. (2007) Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5. J Biol Chem 282:1225-1237. (Pubitemid 47076585)
26. Wilson V, Olivera-Martinez I, Storey KG (2009) Stem cells, signals and vertebrate body axis extension. Development 136:1591-1604.
27. Niwa Y, et al. (2007) The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and Notch signaling in the somite segmentation clock. Dev Cell 13:298-304. (Pubitemid 47163616)
28. Lewandoski M, Sun X, Martin GR (2000) Fgf8 signalling from the AER is essential for normal limb development. Nat Genet 26:460-463.
29. Sun X, Mariani FV, Martin GR (2002) Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature 418:501-508. (Pubitemid 34851390)
30. Moon AM, Capecchi MR (2000) Fgf8 is required for outgrowth and patterning of the limbs. Nat Genet 26:455-459.
31. Sivak JM, Petersen LF, Amaya E (2005) FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation. Dev Cell 8:689-701. (Pubitemid 40585292)
32. Nutt SL, Dingwell KS, Holt CE, Amaya E (2001) Xenopus Sprouty2 inhibits FGFmediated gastrulation movements but does not affect mesoderm induction and patterning. Genes Dev 15:1152-1166. (Pubitemid 32417307)
33. Haremaki T, Fraser ST, Kuo YM, Baron MH, Weinstein DC (2007) Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc Natl Acad Sci USA 104:12029-12034. (Pubitemid 47185624)
34. Yamaguchi TP, Takada S, Yoshikawa Y, Wu N, McMahon AP (1999) T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev 13:3185-3190. (Pubitemid 30030440)
35. Nakayama K, Satoh T, Igari A, Kageyama R, Nishida E (2008) FGF induces oscillations of Hes1 expression and Ras/ERK activation. Curr Biol 18:R332-R334. (Pubitemid 351522463)
36. Ishimatsu K, Takamatsu A, Takeda H (2010) Emergence of traveling waves in the zebrafish segmentation clock. Development 137:1595-1599.
37. Boulet AM, Moon AM, Arenkiel BR, Capecchi MR (2004) The roles of Fgf4 and Fgf8 in limb bud initiation and outgrowth. Dev Biol 273:361-372. (Pubitemid 39140909)
38. Miyagawa S, et al. (2009) Dosage-dependent hedgehog signals integrated with Wnt/β-catenin signaling regulate external genitalia formation as an appendicular program. Development 136:3969-3978.
39. Soshnikova N, et al. (2003) Genetic interaction between Wnt/β-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev 17:1963-1968. (Pubitemid 36999323)
40. Beaster-Jones L, et al. (2008) Expression of somite segmentation genes in amphioxus: A clock without a wavefront? Dev Genes Evol 218:599-611.
41. Kondo T, Zákány J, Innis JW, Duboule D (1997) Of fingers, toes and penises. Nature 390:29.
42. Minelli A (2002) Homology, limbs, and genitalia. Evol Dev 4:127-132.
43. Rossant J, Zirngibl R, Cado D, Shago M, Giguère V (1991) Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes Dev 5:1333-1344. (Pubitemid 21906042)
44. Soriano P (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71.
45. Meyers EN, Lewandoski M, Martin GR (1998) An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat Genet 18:136-141. (Pubitemid 28082459)
46. Wilkinson DG, Nieto MA (1993) Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods Enzymol 225:361-373.
47. Nagy A, Gertsenstein M, Vintersten K, Behringer R (2003) Manipulating the Mouse Embryo (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY).