Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation

FEBS Letters

Volumn 584, Issue 21, 2010, Pages 4383-4388

  Browaeys Poly, Edith ^a   Blanquart, Christophe ^b   Perdereau, Dominique ^b   Antoine, Anne Frédérique ^a   Goenaga, Diana ^b   Luzy, Jean Philippe ^c,d   Chen, Huixiong ^c,d   Garbay, Christiane ^c,d   Issad, Tarik ^b   Cailliau, Katia ^a   Burnol, Anne Françoise ^b  

^a UNIV LILLE   (France)

^b INSTITUT COCHIN   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d INSERM   (France)

Author keywords

BRET; FGFR signaling; PLC gamma; Protein interaction; Xenopus oocyte

Indexed keywords

ADAPTOR PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 14; PHOSPHOLIPASE C GAMMA; PROTEIN SH2; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME BINDING; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL SURVIVAL; ENERGY TRANSFER; ENZYME ACTIVATION; FIBROBLAST GROWTH FACTORS; HUMANS; OOCYTES; PHOSPHOLIPASE C GAMMA; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; SIGNAL TRANSDUCTION; XENOPUS;

EID: 78049237406     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.09.048     Document Type: Article

References (30)

1. Grose R., Dickson C. Fibroblast growth factor signaling in tumorigenesis. Cytokine Growth Factor Rev. 2005, 16:179-186.
2. Eswarakumar V.P., Lax I., Schlessinger J. Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev. 2005, 16:139-149.
3. Dailey L., Ambrosetti D., Mansukhani A., Basilico C. Mechanisms underlying differential responses to FGF signaling. Cytokine Growth Factor Rev. 2005, 16:233-247.
4. Reilly J.F., Mickey G., Maher P.A. Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner. J. Biol. Chem. 2000, 275:7771-7778.
5. Han D.C., Shen T.-L., Guan J.-L. The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions. Oncogene 2001, 20:6315-6321.
6. Bereziat V., Kasus-Jacobi A., Perdereau D., Cariou B., Girard J., Burnol A.F. Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14. J. Biol. Chem. 2002, 277:4845-4852.
7. Depetris R.S., Hu J., Gimpelevich I., Holt L.J., Daly R.J., Hubbard S.R. Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14. Mol. Cell 2005, 20:325-333.
8. Cailliau K., Le Marcis V., Bereziat V., Perdereau D., Cariou B., Vilain J.P., Burnol A.F., Browaeys-Poly E. Inhibition of FGF receptor signalling in Xenopus oocytes: differential effect of Grb7, Grb10 and Grb14. FEBS Lett. 2003, 548:43-48.
9. Cailliau K., Perdereau D., Lescuyer A., Chen H., Garbay C., Vilain J.P., Burnol A.F., Browaeys-Poly E. FGF receptor phosphotyrosine 766 is a target for Grb14 to inhibit MDA-MB-231 human breast cancer cell signaling. Anticancer Res. 2005, 25:3877-3882.
10. Mohammadi M., Honegger A.M., Rotin D., Fischer R., Bellot F., Li W., Dionne C.A., Jaye M., Rubinstein M., Schlessinger J. A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1. Mol. Cell. Biol. 1991, 11:5068-5078.
11. Nouaille S., Blanquart C., Zilberfarb V., Boute N., Perdereau D., Roix J., Burnol A.F., Issad T. Interaction with Grb14 results in site-specific regulation of tyrosine phosphorylation of the insulin receptor. EMBO Rep. 2006, 7:512-518.
12. Browaeys-Poly E., Cailliau K., Vilain J.P. Signal transduction pathways triggered by fibroblast growth factor receptor 1 expressed in Xenopus laevis oocytes after fibroblast growth factor 1 addition. Role of Grb2, phosphatidylinositol 3-kinase, Src tyrosine kinase, and phospholipase Cgamma. Eur. J. Biochem. 2000, 267:6256-6263.
13. Shi D.L., Feige J.J., Riou J.F., DeSimone D.W., Boucaut J.C. Differential expression and regulation of two distinct fibroblast growth factor receptors during early development of the urodele amphibian Pleurodeles waltl. Development 1992, 116:261-273.
14. Browaeys-Poly E., Cailliau K., Vilain J.P. Fibroblast and epidermal growth factor receptor expression in Xenopus oocytes displays distinct calcium oscillatory patterns. Biochim. Biophys. Acta 1998, 1404:484-489.
15. Park S.Y., Barron E., Suh P.G., Ryu S.H., Kay E.P. FGF-2 facilitates binding of SH3 domain of PLC-gamma1 to vinculin and SH2 domains to FGF receptor in corneal endothelial cells. Mol. Vis. 1999, 5:18-25.
16. Dunican D.J., Williams E.J., Howell F.V., Doherty P. Selective inhibition of fibroblast growth factor (FGF)-stimulated mitogenesis by a FGF receptor-1-derived phosphopeptide. Cell Growth Differ. 2001, 12:255-264.
17. Luzy J.P., Chen H., Gril B., Liu W.Q., Vidal M., Perdereau D., Burnol A.F., Garbay C. Development of binding assays for the SH2 domain of Grb7 and Grb2 using fluorescence polarization. J. Biomol. Screen 2008, 13:112-119.
18. Goenaga D., Hampe C., Carre N., Cailliau K., Browaeys-Poly E., Perdereau D., Holt L.J., Daly R.J., Girard J., Broutin I., Issad T., Burnol A.F. Molecular determinants of Grb14-mediated inhibition of insulin signaling. Mol. Endocrinol. 2009, 23:1043-1051.
19. Boute N., Boubekeur S., Lacasa D., Issad T. Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells. EMBO Rep. 2003, 4:313-319.
20. Lacasa D., Boute N., Issad T. Interaction of the insulin receptor with the receptor-like protein tyrosine phosphatases PTPalpha and PTPepsilon in living cells. Mol. Pharmacol. 2005, 67:1206-1213.
21. Muslin A.J., Klippel A., Williams L.T. Phosphatidylinositol 3-kinase activity is important for progesterone-induced Xenopus oocyte maturation. Mol. Cell. Biol. 1993, 13:6661-6666.
22. Chuang L.M., Hausdorff S.F., Myers M.G., White M.F., Birnbaum M.J., Kahn C.R. Interactive roles of Ras, insulin receptor substrate-1, and proteins with Src homology-2 domains in insulin signaling in Xenopus oocytes. J. Biol. Chem. 1994, 269:27645-27649.
23. Browaeys-Poly E., Cailliau K., Vilain J.P. Transduction cascades initiated by fibroblast growth factor 1 on Xenopus oocytes expressing MDA-MB-231 mRNAs. Role of Grb2, phosphatidylinositol 3-kinase, Src tyrosine kinase, and phospholipase Cgamma. Cell. Signal. 2001, 13:363-368.
24. Schmitt A., Nebreda A.R. Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A. Proc. Natl Acad. Sci. USA 2002, 99:4361-4366.
25. Bhatt R.R., Ferrell J.E. Cloning and characterization of Xenopus Rsk2, the predominant p90 Rsk isozyme in oocytes and eggs. J. Biol. Chem. 2000, 275:32983-32990.
26. Poulin B., Sekiya F., Rhee S.G. Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-gamma1. Proc. Natl Acad. Sci. USA 2005, 102:4276-4281.
27. Malo M., Browaeys-Poly E., Fournier F., Cailliau K., Vilain J.P. Ca2+ oscillations induced by fibroblast growth factor 2 in Xenopus oocytes expressing fibroblast growth factor receptors. Mol. Membr. Biol. 1997, 14:205-210.
28. Cariou B., Bereziat V., Moncoq K., Kasus-Jacobi A., Perdereau D., Le Marcis V., Burnol A.F. Regulation and functional roles of Grb14. Front. Biosci. 2004, 9:1626-1636.
29. Klint P., Claesson-Welsh L. Signal transduction by fibroblast growth factor receptors. Front. Biosci. 1999, 4:D165-177.
30. Bae J.H., Lew E.D., Yuzawa S., Tomé F., Lax I., Schlessinger J. The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site. Cell 2009, 138:514-524.