FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity

Journal of Cell Science

Volumn 117, Issue 25, 2004, Pages 6007-6017

  Li, Xuan ^a   Brunton, Valerie G ^b   Burgar, Helen R ^a   Wheldon, Lee M ^a   Heath, John K ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

ERK; FGFR; FRS2; Sprouty; SRC

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 2; PROTEIN TYROSINE KINASE; SPROUTY 2 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL MUTANT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, WESTERN; CELL LINE; DNA, COMPLEMENTARY; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; IMMUNOPRECIPITATION; INDOLES; LIPID METABOLISM; MEMBRANE PROTEINS; MICE; MUTATION; NIH 3T3 CELLS; PEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; SULFONAMIDES; TIME FACTORS; TRANSFECTION; TYROSINE;

EID: 12344278405     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01519     Document Type: Article

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