Phosphatidylinositol 3-kinase activity is critical for glucose metabolism and embryo survival in murine blastocysts

Journal of Biological Chemistry

Volumn 281, Issue 9, 2006, Pages 6010-6019

  Riley, Joan K ^a   Carayannopoulos, Mary O ^a   Wyman, Amanda H ^a   Chi, Maggie ^a   Moley, Kelle H ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Box 8064 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; CELLS; ENZYME INHIBITION; GENETIC ENGINEERING; GLUCOSE; METABOLISM; SIGNALING;

EMBRYO TRANSFER EXPERIMENT; MAMMALIAN DEVELOPMENT; MURINE BLASTOCYSTS; SIGNAL TRANSDUCTION PATHWAYS;

ENZYME KINETICS;

2 MORPHOLINO 8 PHENYLCHROMONE; DEOXYGLUCOSE; GLUCOSE TRANSPORTER 1; PHOSPHATIDYLINOSITOL 3 KINASE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; ENZYME INHIBITOR; GLUCOSE; HEXOKINASE; IODOACETIC ACID; MORPHOLINE DERIVATIVE; SLC2A1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLASTOCYST; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG INHIBITION; FETUS RESORPTION; GLUCOSE METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL MEMBRANE; DRUG ANTAGONISM; EMBRYO; FEMALE; METABOLISM; NICK END LABELING; PHYSIOLOGY; PREGNANCY; PREGNANCY OUTCOME;

MAMMALIA; MURINAE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BLASTOCYST; CELL MEMBRANE; CELLS, CULTURED; CHROMONES; EMBRYO; ENZYME INHIBITORS; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HEXOKINASE; IN SITU NICK-END LABELING; IODOACETATES; MICE; MORPHOLINES; PREGNANCY; PREGNANCY OUTCOME; SIGNAL TRANSDUCTION;

EID: 33646823663     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M506982200     Document Type: Article

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