The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells

Molecular Biology of the Cell

Volumn 13, Issue 8, 2002, Pages 2881-2893

  Cross, Michael J ^a   Lu, Lingge ^a   Magnusson, Peetra ^a   Nyqvist, Daniel ^a   Holmqvist, Kristina ^a   Welsh, Michael ^a   Claesson Welsh, Lena ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CELL PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 1; MEK KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PROTEIN FRS2; PROTEIN KINASE; PROTEIN SHB; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; HELMINTH PROTEINS; MAP KINASE KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOPROTEINS; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SRC HOMOLOGY DOMAINS; SRC-FAMILY KINASES; TYROSINE;

ANIMALIA;

EID: 0036679107     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-02-0103     Document Type: Article

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