-
1
-
-
0029099408
-
Assay and expression of mitogen-activated protein kinase, MAP kinase kinase and Raf
-
Alessi, D.R., Cuenda, A., Cohen, P., Ashworth, A., Cowley, S., Leevers, S.J. and Marshall, C.J. (1995a) Assay and expression of mitogen-activated protein kinase, MAP kinase kinase and Raf. Methods Enzymol., 255, 279-290.
-
(1995)
Methods Enzymol.
, vol.255
, pp. 279-290
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Ashworth, A.4
Cowley, S.5
Leevers, S.J.6
Marshall, C.J.7
-
2
-
-
0028884033
-
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
-
Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T. and Saltiel, A.R., (1995b) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem., 270, 27489-27494.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27489-27494
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
3
-
-
0028841897
-
Phosphotyrosine residues in the nerve growth factor receptor (Trk-A): Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells
-
Baxter, R.M., Cohen, P., Obermeier, A., Ullrich, A., Downes, C.P. and Doza, Y.N. (1995) Phosphotyrosine residues in the nerve growth factor receptor (Trk-A): their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells. Eur. J. Biochem., 234, 84-91.
-
(1995)
Eur. J. Biochem.
, vol.234
, pp. 84-91
-
-
Baxter, R.M.1
Cohen, P.2
Obermeier, A.3
Ullrich, A.4
Downes, C.P.5
Doza, Y.N.6
-
4
-
-
0028806565
-
Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2
-
Ben Levy, R., Leighton, I.A., Doza, Y.N., Attwood, P., Morrice, N., Marshall, C.J. and Cohen, P. (1995) Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2. EMBO J., 14, 101-111.
-
(1995)
EMBO J.
, vol.14
, pp. 101-111
-
-
Ben Levy, R.1
Leighton, I.A.2
Doza, Y.N.3
Attwood, P.4
Morrice, N.5
Marshall, C.J.6
Cohen, P.7
-
5
-
-
0029983730
-
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumour necrosis factor
-
Beyaert, R., Cuenda, A., Vanden Berghe, W., Plaisance, S., Lee, J.C., Haegeman, G., Cohen, P. and Fiers, W. (1996) The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumour necrosis factor. EMBO J., 15, 1914-1923.
-
(1996)
EMBO J.
, vol.15
, pp. 1914-1923
-
-
Beyaert, R.1
Cuenda, A.2
Vanden Berghe, W.3
Plaisance, S.4
Lee, J.C.5
Haegeman, G.6
Cohen, P.7
Fiers, W.8
-
6
-
-
0025806587
-
Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain
-
Binetruy, B., Smeal, T. and Karin, M. (1991) Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature, 351, 122-127.
-
(1991)
Nature
, vol.351
, pp. 122-127
-
-
Binetruy, B.1
Smeal, T.2
Karin, M.3
-
7
-
-
0027943215
-
Opioids modulate stress-induced proenkephalin gene expression in the hypothalamus of transgenic mice: A model of endogenous opioid gene regulation by exogenous opioids
-
Borsook, D., Falkowski, O., Rosen, H., Comb, M. and Hyman, S.E. (1994) Opioids modulate stress-induced proenkephalin gene expression in the hypothalamus of transgenic mice: a model of endogenous opioid gene regulation by exogenous opioids. J. Neurosci., 14(12), 7261-7271.
-
(1994)
J. Neurosci.
, vol.14
, Issue.12
, pp. 7261-7271
-
-
Borsook, D.1
Falkowski, O.2
Rosen, H.3
Comb, M.4
Hyman, S.E.5
-
8
-
-
0028071507
-
Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
-
Bourtchuladze, R., Frenguelli, B., Blendy, J., Cioffi, D., Schutz, G. and Silva, A.J. (1994) Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell, 79, 59-68.
-
(1994)
Cell
, vol.79
, pp. 59-68
-
-
Bourtchuladze, R.1
Frenguelli, B.2
Blendy, J.3
Cioffi, D.4
Schutz, G.5
Silva, A.J.6
-
9
-
-
0024829771
-
Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines
-
Brasier, A., Tate, J.E. and Habener, J.F. (1989) Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines. BioTechmques, 7, 1116-1122.
-
(1989)
BioTechmques
, vol.7
, pp. 1116-1122
-
-
Brasier, A.1
Tate, J.E.2
Habener, J.F.3
-
10
-
-
0028793798
-
Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation
-
Cavigelli, M., Dolfi, F., Claret, F.-X. and Karin, M. (1995) Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation. EMBO J., 14, 5957-5964.
-
(1995)
EMBO J.
, vol.14
, pp. 5957-5964
-
-
Cavigelli, M.1
Dolfi, F.2
Claret, F.-X.3
Karin, M.4
-
11
-
-
0028123698
-
Activating transcription factor-3 stimulates 3′, 5′-cyclic adenosine monophosphate-dependent gene expression
-
Chu, H.-M., Tan, Y., Kobierski, L.A., Balsam, L.B. and Comb, M.J. (1994) Activating transcription factor-3 stimulates 3′, 5′-cyclic adenosine monophosphate-dependent gene expression. Mol. Endocrinol., 8, 59-68.
-
(1994)
Mol. Endocrinol.
, vol.8
, pp. 59-68
-
-
Chu, H.-M.1
Tan, Y.2
Kobierski, L.A.3
Balsam, L.B.4
Comb, M.J.5
-
12
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kDa S6 protein kinases
-
Chung, J., Kuo, C.J., Crabtree, G.R. and Blenis, J. (1992) Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kDa S6 protein kinases. Cell, 69, 1227-1236.
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
13
-
-
0028178928
-
PDGF and insulin-dependent pp70S6K activation mediated by phosphatidylinositol-3-OH kinase
-
Chung, J., Grammer, T.C., Lemon, K.P., Kazlauskas, A. and Blenis, J. (1994) PDGF and insulin-dependent pp70S6K activation mediated by phosphatidylinositol-3-OH kinase. Nature, 370, 71-75.
-
(1994)
Nature
, vol.370
, pp. 71-75
-
-
Chung, J.1
Grammer, T.C.2
Lemon, K.P.3
Kazlauskas, A.4
Blenis, J.5
-
14
-
-
0023665050
-
Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit
-
Clegg, C.H., Correll, L.A., Cadd, G.G. and McKnight, G.S. (1987) Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit. J. Biol. Chem., 262, 13111-13119.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 13111-13119
-
-
Clegg, C.H.1
Correll, L.A.2
Cadd, G.G.3
McKnight, G.S.4
-
15
-
-
0022454057
-
A cyclic AMP- and phorbol ester-inducible DNA element
-
Comb, M., Birnberg, N.C., Seasholtz, A., Herbert, E. and Goodman, H. (1986) A cyclic AMP- and phorbol ester-inducible DNA element. Nature, 323, 353-356.
-
(1986)
Nature
, vol.323
, pp. 353-356
-
-
Comb, M.1
Birnberg, N.C.2
Seasholtz, A.3
Herbert, E.4
Goodman, H.5
-
16
-
-
0343652677
-
Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription
-
Comb, M., Mermod, N., Hyman, S.E., Pearlberg, J., Ross, M.E. and Goodman, H.M. (1988) Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription. EMBO J., 1, 3793-3805.
-
(1988)
EMBO J.
, vol.1
, pp. 3793-3805
-
-
Comb, M.1
Mermod, N.2
Hyman, S.E.3
Pearlberg, J.4
Ross, M.E.5
Goodman, H.M.6
-
17
-
-
0028988138
-
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
-
Cuenda, A., Rouse, J., Doza, Y.N., Meier, R., Cohen, P., Gallagher, T.F., Young, P.R. and Lee, J.C. (1995) SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett., 364, 229-233.
-
(1995)
FEBS Lett.
, vol.364
, pp. 229-233
-
-
Cuenda, A.1
Rouse, J.2
Doza, Y.N.3
Meier, R.4
Cohen, P.5
Gallagher, T.F.6
Young, P.R.7
Lee, J.C.8
-
18
-
-
0029782176
-
Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells
-
Cuenda, A., Alonso, G., Morrice, N., Jones, M., Meier, R., Cohen, P. and Nebreda, A.R. (1996) Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells. EMBO J., 15, 4293-4301.
-
(1996)
EMBO J.
, vol.15
, pp. 4293-4301
-
-
Cuenda, A.1
Alonso, G.2
Morrice, N.3
Jones, M.4
Meier, R.5
Cohen, P.6
Nebreda, A.R.7
-
19
-
-
0027983480
-
Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: An alternative route to mitogen-induced gene expression
-
de Groot, R.P., Ballou, L.M. and Sassone-Corsi, P. (1994) Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression. Cell, 79, 81-91.
-
(1994)
Cell
, vol.79
, pp. 81-91
-
-
Groot, R.P.1
Ballou, L.M.2
Sassone-Corsi, P.3
-
20
-
-
0025522071
-
The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
-
Dent, P., Lavoinne, A., Nakielny, S., Caudwell, F.B., Watt, P. and Cohen, P. (1990) The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle. Nature, 348, 302-308.
-
(1990)
Nature
, vol.348
, pp. 302-308
-
-
Dent, P.1
Lavoinne, A.2
Nakielny, S.3
Caudwell, F.B.4
Watt, P.5
Cohen, P.6
-
21
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Derijard, B., Hibi, M., Wu, I.-H., Barrett, T., Su, B., Deng, T., Karin, M. and Davis, R.J. (1994) JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell, 76, 1025-1037.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.-H.3
Barrett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
22
-
-
0028935974
-
Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms
-
Derijard, B., Raingeaud, J., Barrett, T., Wu, I.-H., Han, J., Ulevitch, R.J. and Davis, R.J. (1995) Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science, 267, 682-685.
-
(1995)
Science
, vol.267
, pp. 682-685
-
-
Derijard, B.1
Raingeaud, J.2
Barrett, T.3
Wu, I.-H.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
23
-
-
0027184723
-
An analysis of the substrate specificity of insulin-stimulated protein kinase-1, a mammalian homologue of S6 kinase-II
-
Donella-Deana, A., Lavoinne, A., Marin, O., Pinna, L.A. and Cohen, P. (1993) An analysis of the substrate specificity of insulin-stimulated protein kinase-1, a mammalian homologue of S6 kinase-II. Biochim. Biophys. Acta, 1178, 189-193.
-
(1993)
Biochim. Biophys. Acta
, vol.1178
, pp. 189-193
-
-
Donella-Deana, A.1
Lavoinne, A.2
Marin, O.3
Pinna, L.A.4
Cohen, P.5
-
24
-
-
0023715225
-
Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP
-
Feig, L.A. and Cooper, G.M. (1988) Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol. Cell. Biol, 8, 3235-3243.
-
(1988)
Mol. Cell. Biol
, vol.8
, pp. 3235-3243
-
-
Feig, L.A.1
Cooper, G.M.2
-
25
-
-
0028015872
-
Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27
-
Freshney, N.W., Rawlinson, L., Guesdon, F., Jones, E., Cowley, S., Hsuan, J. and Saklatvala, J. (1994) Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27. Cell, 78, 1039-1049.
-
(1994)
Cell
, vol.78
, pp. 1039-1049
-
-
Freshney, N.W.1
Rawlinson, L.2
Guesdon, F.3
Jones, E.4
Cowley, S.5
Hsuan, J.6
Saklatvala, J.7
-
26
-
-
0028987937
-
Calcium signaling in neurons: Molecular mechanisms and cellular consequences
-
Ghosh, A., and Greenberg, M.E. (1995) Calcium signaling in neurons: molecular mechanisms and cellular consequences. Science, 268, 239-247.
-
(1995)
Science
, vol.268
, pp. 239-247
-
-
Ghosh, A.1
Greenberg, M.E.2
-
27
-
-
0027213167
-
Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock
-
Ginty, D.D., Kornhauser, J.M., Thompson, M.A., Bading, H., Mayo, K.E., Takahashi, J.S. and Greenberg, M.E. (1993) Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science, 260, 238-241.
-
(1993)
Science
, vol.260
, pp. 238-241
-
-
Ginty, D.D.1
Kornhauser, J.M.2
Thompson, M.A.3
Bading, H.4
Mayo, K.E.5
Takahashi, J.S.6
Greenberg, M.E.7
-
28
-
-
0028338460
-
Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosyphorylation of CREB
-
Ginty, D.D., Bonni, A. and Greenberg, M.E. (1994) Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosyphorylation of CREB. Cell, 77, 713-725.
-
(1994)
Cell
, vol.77
, pp. 713-725
-
-
Ginty, D.D.1
Bonni, A.2
Greenberg, M.E.3
-
29
-
-
0024445798
-
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
-
Gonzalez, G.A. and Montminy, M.R. (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell, 59, 675-680.
-
(1989)
Cell
, vol.59
, pp. 675-680
-
-
Gonzalez, G.A.1
Montminy, M.R.2
-
30
-
-
0028860586
-
The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells
-
Gould, G.W., Cuenda, A., Thomson, F.J. and Cohen, P. (1995) The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells. Biachem. J., 311, 735-738.
-
(1995)
Biachem. J.
, vol.311
, pp. 735-738
-
-
Gould, G.W.1
Cuenda, A.2
Thomson, F.J.3
Cohen, P.4
-
31
-
-
0028905076
-
Transcription factor ATF2 regulation by the JNK signal transduction pathway
-
Gupta, S., Campbell, D., Derijard, B. and Davis, R.J. (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science, 267, 389-393.
-
(1995)
Science
, vol.267
, pp. 389-393
-
-
Gupta, S.1
Campbell, D.2
Derijard, B.3
Davis, R.J.4
-
32
-
-
0027166104
-
Coupling of hormonal stimulation and transcription via the cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A
-
Hagiwara, M., Brindle, P., Harootunian, A., Armstrong, R., Rivier, J., Vale, W., Tsien, R. and Montminy, M.R. (1993) Coupling of hormonal stimulation and transcription via the cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A. Mol. Cell. Biol., 13, 4852-4859.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4852-4859
-
-
Hagiwara, M.1
Brindle, P.2
Harootunian, A.3
Armstrong, R.4
Rivier, J.5
Vale, W.6
Tsien, R.7
Montminy, M.R.8
-
33
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han, J., Lee, J.-D., Bibbs, L. and Ulevitch, R.J. (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science, 265, 808-811.
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.-D.2
Bibbs, L.3
Ulevitch, R.J.4
-
34
-
-
0030044182
-
Characterisation of the structure and function of a novel MAP kinase kinase (MKK6)
-
Han, J., Lee, J.-D., Jiang, J., Li, Z., Feng, L. and Ulevitch, R.J. (1996) Characterisation of the structure and function of a novel MAP kinase kinase (MKK6). J. Biol. Chem., 271, 2886-2891.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2886-2891
-
-
Han, J.1
Lee, J.-D.2
Jiang, J.3
Li, Z.4
Feng, L.5
Ulevitch, R.J.6
-
35
-
-
9544238905
-
JNK/SAPK activation and c-Jun/ATF-2 phosphorylation are insufficient for anisomycin or UV induced nuclear response: An essential role for p38/RK
-
in press
-
Hazzalin, C.A., Cano, E., Cuenda, A., Barratt, M.J., Cohen, P. and Mahadevan, L.C. (1996) JNK/SAPK activation and c-Jun/ATF-2 phosphorylation are insufficient for anisomycin or UV induced nuclear response: an essential role for p38/RK. Curr. Biol., in press.
-
(1996)
Curr. Biol.
-
-
Hazzalin, C.A.1
Cano, E.2
Cuenda, A.3
Barratt, M.J.4
Cohen, P.5
Mahadevan, L.C.6
-
36
-
-
0026721092
-
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase
-
Kuo, C.J., Chung, J., Fiorentino, D.F., Flanagan, W.M., Blenis, J. and Crabtree, G.R. (1992) Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature, 358, 70-73.
-
(1992)
Nature
, vol.358
, pp. 70-73
-
-
Kuo, C.J.1
Chung, J.2
Fiorentino, D.F.3
Flanagan, W.M.4
Blenis, J.5
Crabtree, G.R.6
-
37
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
Kyriakis, J.M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E.A., Ahmad, M.F., Avruch, J. and Woodgett, J.R. (1994) The stress-activated protein kinase subfamily of c-Jun kinases. Nature, 369, 156-160.
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
Dai, T.4
Rubie, E.A.5
Ahmad, M.F.6
Avruch, J.7
Woodgett, J.R.8
-
38
-
-
0025666845
-
Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains
-
Lee, C.Q., Yun, Y., Hoeffler, J.P. and Habener, J.F. (1990) Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains. EMBO J., 9, 4455-4465.
-
(1990)
EMBO J.
, vol.9
, pp. 4455-4465
-
-
Lee, C.Q.1
Yun, Y.2
Hoeffler, J.P.3
Habener, J.F.4
-
39
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee, J.C. et al. (1994a) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature, 372, 739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
-
40
-
-
0027957071
-
Differential effects of the bicyclic imidazoles on cytokine biosynthesis in human monocytes and endothelial cells
-
Lee, J.C., Laydon, J.T. and White, F.J.R. (1994b) Differential effects of the bicyclic imidazoles on cytokine biosynthesis in human monocytes and endothelial cells. Agents Actions, 41, C191-C192.
-
(1994)
Agents Actions
, vol.41
-
-
Lee, J.C.1
Laydon, J.T.2
White, F.J.R.3
-
41
-
-
0023791064
-
The neuroendocrine paraventricular hypothalamus: Receptors, signal transduction mRNA and neurosecretion
-
Lightman, S.L. (1988) The neuroendocrine paraventricular hypothalamus: receptors, signal transduction mRNA and neurosecretion. J. Exp. Biol., 139, 31-49.
-
(1988)
J. Exp. Biol.
, vol.139
, pp. 31-49
-
-
Lightman, S.L.1
-
42
-
-
0023202674
-
Changes in hypothalamic preproenkephalin A mPRNA following stress and opiate withdrawal
-
Lightman, S.L. and Young, W.S., III. (1987) Changes in hypothalamic preproenkephalin A mPRNA following stress and opiate withdrawal. Nature, 328, 643-645.
-
(1987)
Nature
, vol.328
, pp. 643-645
-
-
Lightman, S.L.1
Young III, W.S.2
-
43
-
-
0027764589
-
IL-1 beta modulates the concanavalin-A-induced expression of proenkephalin A mRNA in murine thymocytes
-
Linner, K.M., Nicol, S.E. and Sharp, B.M. (1993) IL-1 beta modulates the concanavalin-A-induced expression of proenkephalin A mRNA in murine thymocytes. J. Pharmacol. Exp. Ther., 267, 1566-1572.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.267
, pp. 1566-1572
-
-
Linner, K.M.1
Nicol, S.E.2
Sharp, B.M.3
-
45
-
-
0028810239
-
Neurotrophic factors and synaptic plasticity
-
Lo, D.C. (1995) Neurotrophic factors and synaptic plasticity. Neuron, 15, 979-981.
-
(1995)
Neuron
, vol.15
, pp. 979-981
-
-
Lo, D.C.1
-
46
-
-
0026779118
-
Differential regulation of proenkephalin expression in astrocytes by cytokines
-
Low, K.G., Allen, R.G. and Melner, M.H. (1992) Differential regulation of proenkephalin expression in astrocytes by cytokines. Endocrinology, 131, 1908-1914.
-
(1992)
Endocrinology
, vol.131
, pp. 1908-1914
-
-
Low, K.G.1
Allen, R.G.2
Melner, M.H.3
-
47
-
-
0027297647
-
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
-
Marais, R., Wynne, J. and Treisman, R. (1993) The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell, 73, 381-393.
-
(1993)
Cell
, vol.73
, pp. 381-393
-
-
Marais, R.1
Wynne, J.2
Treisman, R.3
-
48
-
-
0024623863
-
A DNA cassette containing a trimerized SV40 polyadenylation signal which efficiently blocks spurious plasmid-initiated transcription
-
Maxwell, I.H., Harrison, G.S., Wood, W.M. and Maxwell, F. (1989) A DNA cassette containing a trimerized SV40 polyadenylation signal which efficiently blocks spurious plasmid-initiated transcription. BioTechniques, 7, 276-280.
-
(1989)
BioTechniques
, vol.7
, pp. 276-280
-
-
Maxwell, I.H.1
Harrison, G.S.2
Wood, W.M.3
Maxwell, F.4
-
49
-
-
0029930461
-
Cellular stresses and cytokines activate multiple MAP kinase kinase homologues in PC12 and KB cells
-
Meier, R., Rouse, J., Cuenda, A., Nebreda, A.R. and Cohen, P. (1996) Cellular stresses and cytokines activate multiple MAP kinase kinase homologues in PC12 and KB cells. Eur. J. Biochem., 236, 796-805.
-
(1996)
Eur. J. Biochem.
, vol.236
, pp. 796-805
-
-
Meier, R.1
Rouse, J.2
Cuenda, A.3
Nebreda, A.R.4
Cohen, P.5
-
50
-
-
0025189884
-
The regulation of proenkephalin expression in a distinct population of glial cells
-
Melner, M.H., Low, K.G., Allen, R.G., Nielsen, C.P., Young, S.L. and Saneto, R.P. (1990) The regulation of proenkephalin expression in a distinct population of glial cells. EMBO J., 9, 791-796.
-
(1990)
EMBO J.
, vol.9
, pp. 791-796
-
-
Melner, M.H.1
Low, K.G.2
Allen, R.G.3
Nielsen, C.P.4
Young, S.L.5
Saneto, R.P.6
-
51
-
-
0028168073
-
Activation of p70/p85 S6 kinase by a pathway independent of p21ras
-
Ming, X.-F., Boudewijn, M., Burgering, T., Wennstrom, S., Claesson-Welsh, L., Heldin, C.-H., Bos, J.L., Kozma, S.C. and Thomas, G. (1994) Activation of p70/p85 S6 kinase by a pathway independent of p21ras. Nature, 371, 426-429.
-
(1994)
Nature
, vol.371
, pp. 426-429
-
-
Ming, X.-F.1
Boudewijn, M.2
Burgering, T.3
Wennstrom, S.4
Claesson-Welsh, L.5
Heldin, C.-H.6
Bos, J.L.7
Kozma, S.C.8
Thomas, G.9
-
52
-
-
0026641249
-
Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis
-
Mohammadi, M., Dionne, C.A., Li, W., Li, N., Spivak, T., Honneger, A.M., Jaye, M. and Schlessinger, J. (1992) Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature, 358, 681-684.
-
(1992)
Nature
, vol.358
, pp. 681-684
-
-
Mohammadi, M.1
Dionne, C.A.2
Li, W.3
Li, N.4
Spivak, T.5
Honneger, A.M.6
Jaye, M.7
Schlessinger, J.8
-
53
-
-
0029013236
-
A role for hippocampal opioids in long-term functional plasticity
-
Morris, B.J. and Johnston, H.M. (1995) A role for hippocampal opioids in long-term functional plasticity. Trends Neurosci., 18, 350-355.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 350-355
-
-
Morris, B.J.1
Johnston, H.M.2
-
54
-
-
0026731562
-
2+ flux but not mitogenesis
-
2+ flux but not mitogenesis. Nature, 358, 678-681.
-
(1992)
Nature
, vol.358
, pp. 678-681
-
-
Peters, K.G.1
Marie, J.2
Wilson, E.3
Ives, H.E.4
Escobedo, J.5
Del Rosario, M.6
Mirda, D.7
Williams, L.T.8
-
55
-
-
0026759874
-
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase
-
Price, D.J., Grove, J.R., Calvo, V., Avruch, J. and Bierer, B.E. (1992) Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science, 257, 973-977.
-
(1992)
Science
, vol.257
, pp. 973-977
-
-
Price, D.J.1
Grove, J.R.2
Calvo, V.3
Avruch, J.4
Bierer, B.E.5
-
56
-
-
0026004501
-
Phosphorylation of c-jun mediated by MAP kinases
-
Pulverer, B.J., Kyriakis, J.M., Avruch, J., Nikolakaki, E. and Woodgett, J.R. (1991) Phosphorylation of c-jun mediated by MAP kinases. Nature, 353, 670-674.
-
(1991)
Nature
, vol.353
, pp. 670-674
-
-
Pulverer, B.J.1
Kyriakis, J.M.2
Avruch, J.3
Nikolakaki, E.4
Woodgett, J.R.5
-
57
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
-
Raingeaud, J., Gupta, S., Rogers, J.S., Dickens, M., Han, J., Ulevitch, R.J. and Davis, R.J. (1995) Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem., 270(13), 7420-7426.
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.13
, pp. 7420-7426
-
-
Raingeaud, J.1
Gupta, S.2
Rogers, J.S.3
Dickens, M.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
58
-
-
0030051528
-
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
-
Raingeaud, J., Whitmarsh, A.J., Barrett, T., Derijard, B. and Davis, R.J. (1996) MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol., 16, 1247-1255.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1247-1255
-
-
Raingeaud, J.1
Whitmarsh, A.J.2
Barrett, T.3
Derijard, B.4
Davis, R.J.5
-
59
-
-
0028022750
-
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
-
Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Liamazares, A., Zamanillo, D., Hunt, T. and Nebreda, A.R. (1994) A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell, 78, 1027-1037.
-
(1994)
Cell
, vol.78
, pp. 1027-1037
-
-
Rouse, J.1
Cohen, P.2
Trigon, S.3
Morange, M.4
Alonso-Liamazares, A.5
Zamanillo, D.6
Hunt, T.7
Nebreda, A.R.8
-
60
-
-
0344265606
-
A vector for expressing GAL4(1-147) fusions in mammalian cells
-
Sadowski, I. and Ptashne, M. (1989) A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res., 17, 7539.
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 7539
-
-
Sadowski, I.1
Ptashne, M.2
-
61
-
-
0028558986
-
Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
-
Sanchez, I., Hughes, R.T., Mayer, B.J., Yee, K., Woodgett, J.R., Avruch, J., Kyriakis, J.M. and Zon, L.I. (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Science, 372, 794-798.
-
(1994)
Science
, vol.372
, pp. 794-798
-
-
Sanchez, I.1
Hughes, R.T.2
Mayer, B.J.3
Yee, K.4
Woodgett, J.R.5
Avruch, J.6
Kyriakis, J.M.7
Zon, L.I.8
-
62
-
-
0025807509
-
2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases
-
2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science, 252, 1427-1430.
-
(1991)
Science
, vol.252
, pp. 1427-1430
-
-
Sheng, M.1
Thompson, M.A.2
Greenberg, M.E.3
-
63
-
-
0026733636
-
MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase
-
Stokoe, D., Campbell, D.G., Nakielny, S., Hidaka, H., Leevers, S.J., Marshall, C. and Cohen, P. (1992) MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase. EMBO J., 11, 3985-3994.
-
(1992)
EMBO J.
, vol.11
, pp. 3985-3994
-
-
Stokoe, D.1
Campbell, D.G.2
Nakielny, S.3
Hidaka, H.4
Leevers, S.J.5
Marshall, C.6
Cohen, P.7
-
64
-
-
0027739284
-
The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2
-
Stokoe, D., Caudwell, B., Cohen, P.T.W. and Cohen, P. (1993) The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2. Biochim. J., 296, 843-849.
-
(1993)
Biochim. J.
, vol.296
, pp. 843-849
-
-
Stokoe, D.1
Caudwell, B.2
Cohen, P.T.W.3
Cohen, P.4
-
65
-
-
0023766145
-
Insulin-stimulated MAP2 kinase phosphorylates and activates ribosomal protein S6 kinase
-
Sturgill, T.W., Ray, L.B., Erikson, E. and Maller, J.L. (1988) Insulin-stimulated MAP2 kinase phosphorylates and activates ribosomal protein S6 kinase. Nature, 334, 715-718.
-
(1988)
Nature
, vol.334
, pp. 715-718
-
-
Sturgill, T.W.1
Ray, L.B.2
Erikson, E.3
Maller, J.L.4
-
66
-
-
0027508290
-
Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP kinase-activated kinases 1 and 2
-
Sutherland, C., Alterio, J., Campbell, D.G., Le Bourdelles, B., Mallet, J., Haavik, J. and Cohen, P. (1993) Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP kinase-activated kinases 1 and 2. Eur. J. Biochem., 217, 715-722.
-
(1993)
Eur. J. Biochem.
, vol.217
, pp. 715-722
-
-
Sutherland, C.1
Alterio, J.2
Campbell, D.G.3
Le Bourdelles, B.4
Mallet, J.5
Haavik, J.6
Cohen, P.7
-
67
-
-
0027986766
-
Fibroblast growth factor and cyclic AMP (cAMP) synergistically activate gene expression at a cAMP response element
-
Tan, Y., Low, K.G., Boccia, C., Grossman, J. and Comb, M.J. (1994) Fibroblast growth factor and cyclic AMP (cAMP) synergistically activate gene expression at a cAMP response element. Mol. Cell. Biol., 14(11), 7546-7556.
-
(1994)
Mol. Cell. Biol.
, vol.14
, Issue.11
, pp. 7546-7556
-
-
Tan, Y.1
Low, K.G.2
Boccia, C.3
Grossman, J.4
Comb, M.J.5
-
68
-
-
0020772644
-
Expression of histone genes during heat shock and in arsenite-treated Drosophila Kc cells
-
Tanguay, R.M., Camoto, R., Lettre, F. and Vinvent, M. (1983) Expression of histone genes during heat shock and in arsenite-treated Drosophila Kc cells. Can. J. Biochem. Cell Biol., 61, 414-420.
-
(1983)
Can. J. Biochem. Cell Biol.
, vol.61
, pp. 414-420
-
-
Tanguay, R.M.1
Camoto, R.2
Lettre, F.3
Vinvent, M.4
-
69
-
-
0026534571
-
Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases
-
Thomas, S.M., DeMarco, M., D'Arcangelo, G., Halegoua, S. and Brugge, J.S. (1992) Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell, 68, 1031-1040
-
(1992)
Cell
, vol.68
, pp. 1031-1040
-
-
Thomas, S.M.1
DeMarco, M.2
D'Arcangelo, G.3
Halegoua, S.4
Brugge, J.S.5
-
70
-
-
0027958969
-
Genetic dissection of consolidated memory in Drosophila
-
Tully, T., Preat, T. and Boynton, S.C. (1994) Genetic dissection of consolidated memory in Drosophila. Cell, 79, 35-47.
-
(1994)
Cell
, vol.79
, pp. 35-47
-
-
Tully, T.1
Preat, T.2
Boynton, S.C.3
-
71
-
-
0025472427
-
The effect of depolarization on expression of the human proenkephalin gene is synergistic with cAMP and dependent upon a cAMP-inducible enhancer
-
Van Nguyen, T., Kobierski, L., Comb, M. and Hyman, S.E. (1990) The effect of depolarization on expression of the human proenkephalin gene is synergistic with cAMP and dependent upon a cAMP-inducible enhancer. J. Neurosci., 10, 2825-2833.
-
(1990)
J. Neurosci.
, vol.10
, pp. 2825-2833
-
-
Van Nguyen, T.1
Kobierski, L.2
Comb, M.3
Hyman, S.E.4
-
72
-
-
0028242353
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY29002)
-
Vlahos, C.J., Matter, W.F., Hui, K.Y. and Brown, R.F. (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY29002). J. Biol. Chem., 269, 18961-18967.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18961-18967
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
73
-
-
0025023987
-
Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization
-
Wanaka, A., Johnson, E.M. and Milbrandt, J. (1990) Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization. Neuron, 5, 267-281.
-
(1990)
Neuron
, vol.5
, pp. 267-281
-
-
Wanaka, A.1
Johnson, E.M.2
Milbrandt, J.3
-
74
-
-
0021908896
-
Phorbol ester, calcium ionophore or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000 dalton mammalian stress proteins
-
Welch, W.J. (1985) Phorbol ester, calcium ionophore or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000 dalton mammalian stress proteins. J. Biol. Chem., 260, 3058-3062.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 3058-3062
-
-
Welch, W.J.1
-
75
-
-
0029125757
-
Integration of MAP kinase signal transduction pathways at the serum response element
-
Whitmarsh, A.J., Shore, P., Sharrocks, A.D. and Davis, R.J. (1995) Integration of MAP kinase signal transduction pathways at the serum response element. Science, 269, 403-406.
-
(1995)
Science
, vol.269
, pp. 403-406
-
-
Whitmarsh, A.J.1
Shore, P.2
Sharrocks, A.D.3
Davis, R.J.4
-
76
-
-
0026523559
-
Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
-
Wood, K.W., Sarneck, C., Roberts, T.M. and Blenis, J. (1992) Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell, 68, 1041-1050.
-
(1992)
Cell
, vol.68
, pp. 1041-1050
-
-
Wood, K.W.1
Sarneck, C.2
Roberts, T.M.3
Blenis, J.4
-
77
-
-
0026568913
-
Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons
-
Woodward, W.R., Nishi, R., Meshul, C.K., Williams, T.E., Coulombe, M. and Eckenstein, F.P. (1992) Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons. J. Neurosci., 12, 142-152.
-
(1992)
J. Neurosci.
, vol.12
, pp. 142-152
-
-
Woodward, W.R.1
Nishi, R.2
Meshul, C.K.3
Williams, T.E.4
Coulombe, M.5
Eckenstein, F.P.6
-
78
-
-
0023712739
-
Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB
-
Yamamoto, K.K., Gonzalez, G.A., Biggs, W.H. III and Montminy, M.R. (1988) Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature, 334, 494-498.
-
(1988)
Nature
, vol.334
, pp. 494-498
-
-
Yamamoto, K.K.1
Gonzalez, G.A.2
Biggs III, W.H.3
Montminy, M.R.4
|