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Volumn 29, Issue 17, 2015, Pages 1863-1874

Fgfr1 regulates development through the combinatorial use of signaling proteins

Author keywords

Craniofacial development; Gastrulation; MAPK; Preimplantation; Signaling

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN; PROTEIN CRK; PROTEIN FRS2; PROTEIN PLC GAMMA; UNCLASSIFIED DRUG; FGFR1 PROTEIN, MOUSE; SIGNAL PEPTIDE;

EID: 84965089687     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.264994.115     Document Type: Article
Times cited : (46)

References (63)
  • 2
    • 0032574824 scopus 로고    scopus 로고
    • Targetd disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development
    • Arman E, Haffner-Krausz R, Chen Y, Heath JK, Lonai P. 1998. Targetd disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc Natl Acad Sci 95: 5082-5087.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 5082-5087
    • Arman, E.1    Haffner-Krausz, R.2    Chen, Y.3    Heath, J.K.4    Lonai, P.5
  • 3
    • 61649100307 scopus 로고    scopus 로고
    • The FGF family: Biology, pathophysiology and therapy
    • Beenken A, Mohammadi M. 2009. The FGF family: biology, pathophysiology and therapy. Nat Rev Drug Discov 8: 235-253.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 235-253
    • Beenken, A.1    Mohammadi, M.2
  • 4
    • 0033981729 scopus 로고    scopus 로고
    • Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3′-kinase is essential for male fertility
    • Blume-Jensen P, Jiang G, Hyman R, Lee K-F, O’Gorman S, Hunter T. 2000. Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3′-kinase is essential for male fertility. Nat Genet 24: 157-162.
    • (2000) Nat Genet , vol.24 , pp. 157-162
    • Blume-Jensen, P.1    Jiang, G.2    Hyman, R.3    Lee, K.-F.4    O’Gorman, S.5    Hunter, T.6
  • 7
    • 33646527782 scopus 로고    scopus 로고
    • Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway
    • Chazaud C, Yamanaka Y, Pawson T, Rossant J. 2006. Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell 10: 615-624.
    • (2006) Dev Cell , vol.10 , pp. 615-624
    • Chazaud, C.1    Yamanaka, Y.2    Pawson, T.3    Rossant, J.4
  • 9
    • 0035408007 scopus 로고    scopus 로고
    • Fgf signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak
    • Ciruna B, Rossant J. 2001. Fgf signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev Cell 1: 37-49.
    • (2001) Dev Cell , vol.1 , pp. 37-49
    • Ciruna, B.1    Rossant, J.2
  • 10
    • 0030743776 scopus 로고    scopus 로고
    • Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: A role for FGFR1 in morphogenicmovement through the primitive streak
    • Ciruna B, Schwartz L, Harpal K, Yamaguchi TP, Rossant J. 1997. Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenicmovement through the primitive streak. Development 124: 2829-2841.
    • (1997) Development , vol.124 , pp. 2829-2841
    • Ciruna, B.1    Schwartz, L.2    Harpal, K.3    Yamaguchi, T.P.4    Rossant, J.5
  • 11
    • 0032481124 scopus 로고    scopus 로고
    • Modification of gene activity in mouse embryos in utero by tamoxifen-inducible form of Cre recombinase
    • Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. 1998. Modification of gene activity in mouse embryos in utero by tamoxifen-inducible form of Cre recombinase. Curr Biol 8: 1323-1326.
    • (1998) Curr Biol , vol.8 , pp. 1323-1326
    • Danielian, P.S.1    Muccino, D.2    Rowitch, D.H.3    Michael, S.K.4    McMahon, A.P.5
  • 12
  • 14
    • 78149263789 scopus 로고    scopus 로고
    • FGF signalling: Diverse roles during early vertebrate embryogenesis
    • Dorey K, Amaya E. 2010. FGF signalling: diverse roles during early vertebrate embryogenesis. Development 137: 3731-3742.
    • (2010) Development , vol.137 , pp. 3731-3742
    • Dorey, K.1    Amaya, E.2
  • 15
    • 77951043677 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription-3 binding to the fibroblast growth factor receptor is activated by receptor amplification
    • Dudka AA, Sweet SMM, Heath JK. 2010. Signal transducers and activators of transcription-3 binding to the fibroblast growth factor receptor is activated by receptor amplification. Cancer Res 70: 3391-3401.
    • (2010) Cancer Res , vol.70 , pp. 3391-3401
    • Dudka, A.A.1    Sweet, S.2    Heath, J.K.3
  • 20
    • 0037644786 scopus 로고    scopus 로고
    • Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm
    • Goldin SN, Papaioannou VE. 2003. Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm. Genesis 36: 40-47.
    • (2003) Genesis , vol.36 , pp. 40-47
    • Goldin, S.N.1    Papaioannou, V.E.2
  • 21
    • 1842850649 scopus 로고    scopus 로고
    • Frs2 family docking proteins with overlapping roles in activation of Map kinase have distinct spatial-temporal patterns of expression of their transcripts
    • Gotoh N, Laks S, Nakashima M, Lax I, Schlessinger J. 2004a. Frs2 family docking proteins with overlapping roles in activation of Map kinase have distinct spatial-temporal patterns of expression of their transcripts. FEBS Lett 564: 14-18.
    • (2004) FEBS Lett , vol.564 , pp. 14-18
    • Gotoh, N.1    Laks, S.2    Nakashima, M.3    Lax, I.4    Schlessinger, J.5
  • 22
    • 20144372283 scopus 로고    scopus 로고
    • The docking protein Frs2a is an essential component of multiple fibroblast growth factor responses during early mouse development
    • Gotoh N, Manova K, Tanaka S, Murohashi M, Hadari Y, Lee A, Hamada Y, Hiroe T, Ito M, Kurihara T, et al. 2004b. The docking protein Frs2a is an essential component of multiple fibroblast growth factor responses during early mouse development. Mol Cell Biol 25: 4105-4116.
    • (2004) Mol Cell Biol , vol.25 , pp. 4105-4116
    • Gotoh, N.1    Manova, K.2    Tanaka, S.3    Murohashi, M.4    Hadari, Y.5    Lee, A.6    Hamada, Y.7    Hiroe, T.8    Ito, M.9    Kurihara, T.10
  • 23
    • 0035098436 scopus 로고    scopus 로고
    • Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge Syndrome
    • Guris DL, Fantes J, Tara D, Druker BJ, Imamoto A. 2001. Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge Syndrome. Nat Genet 27: 293-298.
    • (2001) Nat Genet , vol.27 , pp. 293-298
    • Guris, D.L.1    Fantes, J.2    Tara, D.3    Druker, B.J.4    Imamoto, A.5
  • 24
    • 0035902581 scopus 로고    scopus 로고
    • Critical role for docking-protein Frs2a in FGF receptor-mediated signal transduction pathways
    • Hadari YR, Gotoh N, Kouhara H, Lax I, Schlessinger J. 2001. Critical role for docking-protein Frs2a in FGF receptor-mediated signal transduction pathways. Proc Natl Acad Sci 98: 8578-8583.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 8578-8583
    • Hadari, Y.R.1    Gotoh, N.2    Kouhara, H.3    Lax, I.4    Schlessinger, J.5
  • 25
    • 84876188256 scopus 로고    scopus 로고
    • Erk2 supresses self-renewal capacity of embryonic stem cells, but is not required for multi-lineage commitment
    • Hamilton WB, Kaji K, Kunath T. 2013. Erk2 supresses self-renewal capacity of embryonic stem cells, but is not required for multi-lineage commitment. PLos One 8: e60907.
    • (2013) Plos One , vol.8
    • Hamilton, W.B.1    Kaji, K.2    Kunath, T.3
  • 27
    • 0141784138 scopus 로고    scopus 로고
    • Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectroscopy
    • Hinsby AM, Olsen JV, Bennett KL, Mann M. 2003. Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectroscopy. Mol Cell Proteomics 2: 29-36.
    • (2003) Mol Cell Proteomics , vol.2 , pp. 29-36
    • Hinsby, A.M.1    Olsen, J.V.2    Bennett, K.L.3    Mann, M.4
  • 28
    • 33645068866 scopus 로고    scopus 로고
    • Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 mouse development
    • Hoch R, Soriano P. 2006. Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 mouse development. Development 133: 663-673.
    • (2006) Development , vol.133 , pp. 663-673
    • Hoch, R.1    Soriano, P.2
  • 29
    • 0028986599 scopus 로고
    • Reduced activation of Raf-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis
    • Huang J, Mohammadi M, Rodriguez GA, Schlessinger J. 1995. Reduced activation of Raf-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis. J Biol Chem 270: 5065-5072.
    • (1995) J Biol Chem , vol.270 , pp. 5065-5072
    • Huang, J.1    Mohammadi, M.2    Rodriguez, G.A.3    Schlessinger, J.4
  • 30
    • 84871561933 scopus 로고    scopus 로고
    • FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse
    • Kang M, Piliszek A, Artus J, Hadjantonakis A-K. 2013. FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse. Development 140: 267-279.
    • (2013) Development , vol.140 , pp. 267-279
    • Kang, M.1    Piliszek, A.2    Artus, J.3    Hadjantonakis, A.-K.4
  • 31
    • 0036007120 scopus 로고    scopus 로고
    • An allelic series at PDGFaR locus indicates unequal contributions of distinct signaling pathways during development
    • Klinghoffer RA, Hamilton TG, Hoch R, Soriano P. 2002. An allelic series at PDGFaR locus indicates unequal contributions of distinct signaling pathways during development. Dev Cell 2: 103-113.
    • (2002) Dev Cell , vol.2 , pp. 103-113
    • Klinghoffer, R.A.1    Hamilton, T.G.2    Hoch, R.3    Soriano, P.4
  • 32
    • 0030706168 scopus 로고    scopus 로고
    • A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
    • Kouhara H, Hadari Y, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I, Schlessinger J. 1997. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89: 693-702.
    • (1997) Cell , vol.89 , pp. 693-702
    • Kouhara, H.1    Hadari, Y.2    Spivak-Kroizman, T.3    Schilling, J.4    Bar-Sagi, D.5    Lax, I.6    Schlessinger, J.7
  • 33
    • 34548587064 scopus 로고    scopus 로고
    • FGF stimulation of the ERK1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
    • Kunath T, Saba-El-Leil M, Almousailleakh M, Wray J, Meloche S, Smith A. 2007. FGF stimulation of the ERK1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development 134: 2895-2902.
    • (2007) Development , vol.134 , pp. 2895-2902
    • Kunath, T.1    Saba-El-Leil, M.2    Almousailleakh, M.3    Wray, J.4    Meloche, S.5    Smith, A.6
  • 34
    • 77957669746 scopus 로고    scopus 로고
    • The role of FGF/Erk signaling in pluripotent cells
    • Lanner F, Rossant J. 2010. The role of FGF/Erk signaling in pluripotent cells. Development 137: 3351-3360.
    • (2010) Development , vol.137 , pp. 3351-3360
    • Lanner, F.1    Rossant, J.2
  • 35
    • 0033520278 scopus 로고    scopus 로고
    • Fibroblasts growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH)2/SH3 domain-containing adaptor protein Crk
    • Larsson H, Klint P, Landgren E, Claesson-Welsh L. 1999. Fibroblasts growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH)2/SH3 domain-containing adaptor protein Crk. J Biol Chem 274: 25726-25734.
    • (1999) J Biol Chem , vol.274 , pp. 25726-25734
    • Larsson, H.1    Klint, P.2    Landgren, E.3    Claesson-Welsh, L.4
  • 37
    • 0035019115 scopus 로고    scopus 로고
    • Developmental expression patterns of the signaling adaptors FRS-2 and FRS-3 during early embryogenesis
    • McDougall K, Kubu C, Verdi JM, Meakin SO. 2001. Developmental expression patterns of the signaling adaptors FRS-2 and FRS-3 during early embryogenesis. Mech Dev 103: 145-148.
    • (2001) Mech Dev , vol.103 , pp. 145-148
    • McDougall, K.1    Kubu, C.2    Verdi, J.M.3    Meakin, S.O.4
  • 38
    • 0025941527 scopus 로고
    • A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-γ1
    • Mohammadi M, Honegger AM, Rotin D, Fischer R, Bellot F, Li W, Dionne CA, Jaye M, Rubinstein M, Schlessinger J. 1991. A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (flg) is a binding site for the SH2 domain of phospholipase C-γ1. Mol Cell Biol 11: 5068-5078.
    • (1991) Mol Cell Biol , vol.11 , pp. 5068-5078
    • Mohammadi, M.1    Honegger, A.M.2    Rotin, D.3    Fischer, R.4    Bellot, F.5    Li, W.6    Dionne, C.A.7    Jaye, M.8    Rubinstein, M.9    Schlessinger, J.10
  • 39
    • 0026641249 scopus 로고
    • Point mutation in FGF receptor eliminates phosphosphatidylinositol hydrolysis without affecting mitogenesis
    • Mohammadi M, Dionne C, Li W, Li N, Spivak T, Honegger A, Jaye M, Schlessinger J. 1992. Point mutation in FGF receptor eliminates phosphosphatidylinositol hydrolysis without affecting mitogenesis. Nature 358: 681-684.
    • (1992) Nature , vol.358 , pp. 681-684
    • Mohammadi, M.1    Dionne, C.2    Li, W.3    Li, N.4    Spivak, T.5    Honegger, A.6    Jaye, M.7    Schlessinger, J.8
  • 40
    • 29744440528 scopus 로고    scopus 로고
    • Crkl deficiency disrupts fgf8 signaling in a mouse model of 22q11 deletion syndromes
    • Moon AM, Guris DL, Seo J-h, Li L, Hammond J, Talbot A, Imamoto A. 2006. Crkl deficiency disrupts fgf8 signaling in a mouse model of 22q11 deletion syndromes. Dev Cell 10: 71-80.
    • (2006) Dev Cell , vol.10 , pp. 71-80
    • Moon, A.M.1    Guris, D.L.2    Seo, J.-H.3    Li, L.4    Hammond, J.5    Talbot, A.6    Imamoto, A.7
  • 41
    • 84896739105 scopus 로고    scopus 로고
    • The differential response to Fgf signalling in cells internalized at different times influences lineage segregation in preimplantation mouse embryos
    • Morris SA, Graham SJ, Jedrusik A, Zernica-Goetz M. 2013. The differential response to Fgf signalling in cells internalized at different times influences lineage segregation in preimplantation mouse embryos. Open Biol 3: 130104.
    • (2013) Open Biol , vol.3
    • Morris, S.A.1    Graham, S.J.2    Jedrusik, A.3    Zernica-Goetz, M.4
  • 42
    • 70349934958 scopus 로고    scopus 로고
    • Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
    • Nichols J, Silva J, Roode M, Smith A. 2009. Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development 136: 3215-3222.
    • (2009) Development , vol.136 , pp. 3215-3222
    • Nichols, J.1    Silva, J.2    Roode, M.3    Smith, A.4
  • 43
    • 0035336772 scopus 로고    scopus 로고
    • Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and paterning
    • Nutt S, Dingwell K, Holt C, Amaya E. 2001. Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and paterning. Genes Dev 15: 1152-1166.
    • (2001) Genes Dev , vol.15 , pp. 1152-1166
    • Nutt, S.1    Dingwell, K.2    Holt, C.3    Amaya, E.4
  • 45
    • 0033974109 scopus 로고    scopus 로고
    • Frs2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors
    • Ong SH, Guy GR, Hadari YR, Laks S, Gotoh N, Schlessinger J, Lax I. 2000. Frs2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. Mol Cell Biol 20: 979-989.
    • (2000) Mol Cell Biol , vol.20 , pp. 979-989
    • Ong, S.H.1    Guy, G.R.2    Hadari, Y.R.3    Laks, S.4    Gotoh, N.5    Schlessinger, J.6    Lax, I.7
  • 46
    • 0035933094 scopus 로고    scopus 로고
    • Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated requirement of multiple docking proteins
    • Ong SH, Hadari Y, Gotoh N, Guy GR, Schlessinger J, Lax I. 2001. Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated requirement of multiple docking proteins. Proc Natl Acad Sci 98: 6074-6079.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 6074-6079
    • Ong, S.H.1    Hadari, Y.2    Gotoh, N.3    Guy, G.R.4    Schlessinger, J.5    Lax, I.6
  • 47
    • 84926520018 scopus 로고    scopus 로고
    • The fibroblast growth factor signaling pathway
    • Ornitz DM, Itoh N. 2015. The fibroblast growth factor signaling pathway. Wiley Interdiscip Rev Dev Biol 4: 215-266.
    • (2015) Wiley Interdiscip Rev Dev Biol , vol.4 , pp. 215-266
    • Ornitz, D.M.1    Itoh, N.2
  • 48
    • 0032146074 scopus 로고    scopus 로고
    • Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryo
    • Partanen J, Schwartz L, Rossant J. 1998. Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryo. Genes Dev 12: 2332-2344.
    • (1998) Genes Dev , vol.12 , pp. 2332-2344
    • Partanen, J.1    Schwartz, L.2    Rossant, J.3
  • 49
    • 0034677773 scopus 로고    scopus 로고
    • Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14
    • Reilly JF, Mickey G, Maher PA. 2000. Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. J Biol Chem 275: 7771-7778.
    • (2000) J Biol Chem , vol.275 , pp. 7771-7778
    • Reilly, J.F.1    Mickey, G.2    Maher, P.A.3
  • 51
    • 84870057466 scopus 로고    scopus 로고
    • Whole mount nuclear fluorescent imaging: Convenient documentation of embryo morphology
    • Sandell LL, Kurosaka H, Trainor PA. 2012. Whole mount nuclear fluorescent imaging: convenient documentation of embryo morphology. Genesis 50: 844-850.
    • (2012) Genesis , vol.50 , pp. 844-850
    • Sandell, L.L.1    Kurosaka, H.2    Trainor, P.A.3
  • 52
    • 33845894956 scopus 로고    scopus 로고
    • PDGF signaling specificity is mediated through multiple immediate early genes
    • Schmahl J, Raymond C, Soriano P. 2007. PDGF signaling specificity is mediated through multiple immediate early genes. Nat Genet 39: 52-60.
    • (2007) Nat Genet , vol.39 , pp. 52-60
    • Schmahl, J.1    Raymond, C.2    Soriano, P.3
  • 53
    • 17844381597 scopus 로고    scopus 로고
    • FGF Signal interpretation is directed by sprouty and spred proteins during mesoderm formation
    • Sivak J, Petersen L, Amaya E. 2005. FGF Signal interpretation is directed by sprouty and spred proteins during mesoderm formation. Dev Cell 8: 689-701.
    • (2005) Dev Cell , vol.8 , pp. 689-701
    • Sivak, J.1    Petersen, L.2    Amaya, E.3
  • 54
    • 0028356454 scopus 로고
    • Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766
    • Sorokin A, Mohammadi M, Huang J, Schlessinger J. 1994. Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766. J Biol Chem 269: 17056-17061.
    • (1994) J Biol Chem , vol.269 , pp. 17056-17061
    • Sorokin, A.1    Mohammadi, M.2    Huang, J.3    Schlessinger, J.4
  • 55
    • 34548596749 scopus 로고    scopus 로고
    • A discrete period of FGF-induced Erk1/2 signaling is required for vertebrate neural specification
    • Stavridis MP, Lunn JS, Collins BJ, Storey KG. 2007. A discrete period of FGF-induced Erk1/2 signaling is required for vertebrate neural specification. Development 134: 2889-2894.
    • (2007) Development , vol.134 , pp. 2889-2894
    • Stavridis, M.P.1    Lunn, J.S.2    Collins, B.J.3    Storey, K.G.4
  • 56
    • 0032213273 scopus 로고    scopus 로고
    • Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell-specific Stat3-deficient mice
    • Takeda K, Kaisho T, Yoshida N, Takeda J, Kishimoto T, Akira S. 1998. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J Immunol 161: 4652-4660.
    • (1998) J Immunol , vol.161 , pp. 4652-4660
    • Takeda, K.1    Kaisho, T.2    Yoshida, N.3    Takeda, J.4    Kishimoto, T.5    Akira, S.6
  • 57
    • 0034114458 scopus 로고    scopus 로고
    • Epiblast-restricted Cre expression in MORE mice: A tool to distinguish embryonic vs. Extra-embryonic gene function
    • Tallquist MD, Soriano P. 2000. Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. Genesis 26: 113-115.
    • (2000) Genesis , vol.26 , pp. 113-115
    • Tallquist, M.D.1    Soriano, P.2
  • 58
    • 2342419356 scopus 로고    scopus 로고
    • Additive effects of PDGF receptor β signaling pathways in vascular smooth muscle cell development
    • Tallquist MD, French WJ, Soriano P. 2003. Additive effects of PDGF receptor β signaling pathways in vascular smooth muscle cell development. PLoS Biol 1: 288-299.
    • (2003) Plos Biol , vol.1 , pp. 288-299
    • Tallquist, M.D.1    French, W.J.2    Soriano, P.3
  • 59
    • 0037227318 scopus 로고    scopus 로고
    • Fgfr1 regulates patterning of the pharyngeal region
    • Trokovic N, Trokovic R, Mai P, Partanen J. 2003. Fgfr1 regulates patterning of the pharyngeal region. Genes Dev 17: 141-153.
    • (2003) Genes Dev , vol.17 , pp. 141-153
    • Trokovic, N.1    Trokovic, R.2    Mai, P.3    Partanen, J.4
  • 60
    • 27144547208 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling and regional specification of the pharyngeal ectoderm
    • Trokovic N, Trokovic R, Partanen J. 2005. Fibroblast growth factor signalling and regional specification of the pharyngeal ectoderm. Int J Dev Biol 49: 797-805.
    • (2005) Int J Dev Biol , vol.49 , pp. 797-805
    • Trokovic, N.1    Trokovic, R.2    Partanen, J.3
  • 61
    • 84922729893 scopus 로고    scopus 로고
    • SRF Regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling
    • Vasudevan HN, Soriano P. 2014. SRF Regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling. Dev Cell 31: 332-344.
    • (2014) Dev Cell , vol.31 , pp. 332-344
    • Vasudevan, H.N.1    Soriano, P.2
  • 62
    • 0028582035 scopus 로고
    • Fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation
    • Yamaguchi TP, Harpal K, Henkemeyer M, Rossant J. 1994. Fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev 8: 3032-3044.
    • (1994) Genes Dev , vol.8 , pp. 3032-3044
    • Yamaguchi, T.P.1    Harpal, K.2    Henkemeyer, M.3    Rossant, J.4
  • 63
    • 76449083746 scopus 로고    scopus 로고
    • FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocysts
    • Yamanaka Y, Lanner F, Rossant J. 2010. FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocysts. Development 137: 715-724.
    • (2010) Development , vol.137 , pp. 715-724
    • Yamanaka, Y.1    Lanner, F.2    Rossant, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.