-
1
-
-
0035081241
-
Fibroblast growth factors
-
reviews 3005
-
Ornitz, D.M. & Itoh, N. Fibroblast growth factors. Genome Biol. 2, reviews 3005 (2001).
-
(2001)
Genome Biol
, vol.2
-
-
Ornitz, D.M.1
Itoh, N.2
-
2
-
-
17844402791
-
Bad bone, absent smell, selfish testes: The pleiotropic consequences of human FGF receptor mutations
-
Wilkie, A.O.M. Bad bone, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations. Cytokine Growth Factor Rev. 16, 187-203 (2005).
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 187-203
-
-
Wilkie, A.O.M.1
-
3
-
-
38449096256
-
FGF signaling: Its role in bone development and human skeleton diseases
-
Su, N., Du, X. & Chen, L. FGF signaling: its role in bone development and human skeleton diseases. Front. Biosci. 13, 2842-2865 (2008).
-
(2008)
Front. Biosci
, vol.13
, pp. 2842-2865
-
-
Su, N.1
Du, X.2
Chen, L.3
-
4
-
-
0037097976
-
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease
-
Ornitz, D.M. & Marie, P.J. FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes Dev. 16, 1446-1465 (2002).
-
(2002)
Genes Dev
, vol.16
, pp. 1446-1465
-
-
Ornitz, D.M.1
Marie, P.J.2
-
5
-
-
2642595047
-
The roles of FGFs in the early development of vertebrate limbs
-
Martin, G.R. The roles of FGFs in the early development of vertebrate limbs. Genes Dev. 12, 1571-1586 (1998).
-
(1998)
Genes Dev
, vol.12
, pp. 1571-1586
-
-
Martin, G.R.1
-
6
-
-
18144391965
-
FGF signaling in the developing endochondral skeleton
-
Ornitz, D.M. FGF signaling in the developing endochondral skeleton. Cytokine Growth Factor Rev. 16, 205-213 (2005).
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 205-213
-
-
Ornitz, D.M.1
-
7
-
-
0034007273
-
Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation
-
Montero, A. et al. Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation. J. Clin. Invest. 105, 1085-1093 (2000).
-
(2000)
J. Clin. Invest
, vol.105
, pp. 1085-1093
-
-
Montero, A.1
-
8
-
-
34347248067
-
FGF9 regulates early hypertrophic chondrocyte differentiation and skeketal vascularization in the developing stylopod
-
Hung, I.H., Yu, K., Lavine, K.J. & Ornitz, D.M. FGF9 regulates early hypertrophic chondrocyte differentiation and skeketal vascularization in the developing stylopod. Dev. Biol. 307, 300-313 (2007).
-
(2007)
Dev. Biol
, vol.307
, pp. 300-313
-
-
Hung, I.H.1
Yu, K.2
Lavine, K.J.3
Ornitz, D.M.4
-
9
-
-
0036203355
-
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18
-
Liu, Z., Xu, J., Colvin, J.S. & Ornitz, D.M. Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 16, 859-869 (2002).
-
(2002)
Genes Dev
, vol.16
, pp. 859-869
-
-
Liu, Z.1
Xu, J.2
Colvin, J.S.3
Ornitz, D.M.4
-
10
-
-
0036205735
-
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
-
Ohbayashi, N. et al. FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 16, 870-879 (2002).
-
(2002)
Genes Dev
, vol.16
, pp. 870-879
-
-
Ohbayashi, N.1
-
11
-
-
0032759872
-
Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice
-
Garofalo, S. et al. Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice. J. Bone Miner. Res. 14, 1909-1915 (1999).
-
(1999)
J. Bone Miner. Res
, vol.14
, pp. 1909-1915
-
-
Garofalo, S.1
-
12
-
-
0033951768
-
heparan sulfate and FGFRs: Complex interactions essential for development
-
Ornitz, D.M. FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays 22, 108-112 (2000).
-
(2000)
Bioessays
, vol.22
, pp. 108-112
-
-
Ornitz, D.M.F.1
-
13
-
-
0037137480
-
Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila
-
Nybakken, K. & Perrimon, N. Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila. Biochim. Biophys. Acta 1573, 280-291 (2002).
-
(2002)
Biochim. Biophys. Acta
, vol.1573
, pp. 280-291
-
-
Nybakken, K.1
Perrimon, N.2
-
14
-
-
0035830878
-
Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition
-
Plotnikov, A.N. et al. Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition. J. Biol. Chem. 276, 4322-4329 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 4322-4329
-
-
Plotnikov, A.N.1
-
15
-
-
0035093083
-
Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces
-
Hecht, H.J. et al. Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces. Acta Crystallogr. D Biol. Crystallogr. 57, 378-384 (2001).
-
(2001)
Acta Crystallogr. D Biol. Crystallogr
, vol.57
, pp. 378-384
-
-
Hecht, H.J.1
-
16
-
-
0036017941
-
Elbow knee synostosis (Eks): A new mutation on mouse Chromosome 14
-
Murakami, H. et al. Elbow knee synostosis (Eks): a new mutation on mouse Chromosome 14. Mamm. Genome 13, 341-344 (2002).
-
(2002)
Mamm. Genome
, vol.13
, pp. 341-344
-
-
Murakami, H.1
-
17
-
-
15844368097
-
Receptor specificity of the fibroblast growth factor family
-
Ornitz, D.M. et al. Receptor specificity of the fibroblast growth factor family. J. Biol. Chem. 271, 15292-15297 (1996).
-
(1996)
J. Biol. Chem
, vol.271
, pp. 15292-15297
-
-
Ornitz, D.M.1
-
18
-
-
0036126130
-
Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development
-
Hajihosseini, M.K. & Heath, J.K. Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech. Dev. 113, 79-83 (2002).
-
(2002)
Mech. Dev
, vol.113
, pp. 79-83
-
-
Hajihosseini, M.K.1
Heath, J.K.2
-
19
-
-
0032857909
-
Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene
-
Colvin, J.S., Feldman, B., Nadeau, J.H., Goldfarb, M. & Ornitz, D.M. Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene. Dev. Dyn. 216, 72-88 (1999).
-
(1999)
Dev. Dyn
, vol.216
, pp. 72-88
-
-
Colvin, J.S.1
Feldman, B.2
Nadeau, J.H.3
Goldfarb, M.4
Ornitz, D.M.5
-
20
-
-
0034772675
-
Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains
-
Wang, Q., Green, R.P., Zhao, G. & Ornitz, D.M. Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains. Development 128, 3867-3876 (2001).
-
(2001)
Development
, vol.128
, pp. 3867-3876
-
-
Wang, Q.1
Green, R.P.2
Zhao, G.3
Ornitz, D.M.4
-
21
-
-
4344689004
-
A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis
-
Eswarakumar, V.P., Horowitz, M.C., Locklin, R., Morriss-Kay, G.M. & Lonai, P. A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis. Proc. Natl. Acad. Sci. USA 101, 12555-12560 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12555-12560
-
-
Eswarakumar, V.P.1
Horowitz, M.C.2
Locklin, R.3
Morriss-Kay, G.M.4
Lonai, P.5
-
22
-
-
0030481707
-
Joint patterning defects caused by single and double mutations in members of the bone morphogenetic protein (BMP) family
-
Storm, E.E. & Kingsley, D.M. Joint patterning defects caused by single and double mutations in members of the bone morphogenetic protein (BMP) family. Development 122, 3969-3979 (1996).
-
(1996)
Development
, vol.122
, pp. 3969-3979
-
-
Storm, E.E.1
Kingsley, D.M.2
-
23
-
-
0029010445
-
Collagen gene expression during development of avian synovial joints: Transient expression of types II and XI collagen genes in the joint capsule
-
Nalin, A.M., Greenlee, T.K. & Sandell, L.J. Collagen gene expression during development of avian synovial joints: Transient expression of types II and XI collagen genes in the joint capsule. Dev. Dyn. 203, 352-362 (1995).
-
(1995)
Dev. Dyn
, vol.203
, pp. 352-362
-
-
Nalin, A.M.1
Greenlee, T.K.2
Sandell, L.J.3
-
24
-
-
0030833319
-
Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2
-
Iseki, S. et al. Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. Development 124, 3375-3384 (1997).
-
(1997)
Development
, vol.124
, pp. 3375-3384
-
-
Iseki, S.1
-
25
-
-
19044393472
-
Twist is required for establishment of the mouse coronal suture
-
Yoshida, T. et al. Twist is required for establishment of the mouse coronal suture. J. Anat. 206, 437-444 (2005).
-
(2005)
J. Anat
, vol.206
, pp. 437-444
-
-
Yoshida, T.1
-
26
-
-
0025001394
-
Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor
-
Flaumenhaft, R., Moscatelli, D. & Rifkin, D.B. Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor. J. Cell Biol. 111, 1651-1659 (1990).
-
(1990)
J. Cell Biol
, vol.111
, pp. 1651-1659
-
-
Flaumenhaft, R.1
Moscatelli, D.2
Rifkin, D.B.3
-
27
-
-
18744372751
-
Calculation of absolute protein-ligand binding free energy from computer simulations
-
Woo, H.J. & Roux, B. Calculation of absolute protein-ligand binding free energy from computer simulations. Proc. Natl. Acad. Sci. USA 102, 6825-6830 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 6825-6830
-
-
Woo, H.J.1
Roux, B.2
-
28
-
-
0033635299
-
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization
-
Schlessinger, J. et al. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol. Cell 6, 743-750 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 743-750
-
-
Schlessinger, J.1
-
29
-
-
0033582420
-
Heparan sulfate mediates bFGF transport through basement membrane by diffusion with rapid reversible binding
-
Dowd, C.J., Cooney, C.L. & Nugent, M.A. Heparan sulfate mediates bFGF transport through basement membrane by diffusion with rapid reversible binding. J. Biol. Chem. 274, 5236-5244 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 5236-5244
-
-
Dowd, C.J.1
Cooney, C.L.2
Nugent, M.A.3
-
30
-
-
0034002459
-
Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for Twist in suture initiation and biogenesis
-
Johnson, D., Iseki, S., Wilkie, A.O.M. & Morriss-Kay, G.M. Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for Twist in suture initiation and biogenesis. Mech. Dev. 91, 341-345 (2000).
-
(2000)
Mech. Dev
, vol.91
, pp. 341-345
-
-
Johnson, D.1
Iseki, S.2
Wilkie, A.O.M.3
Morriss-Kay, G.M.4
-
31
-
-
2342483086
-
Promotion and attenuation of FGF signaling through the Ras-MAPK pathway
-
pe17 2004
-
Tsang, M. & Dawid, I.B. Promotion and attenuation of FGF signaling through the Ras-MAPK pathway. Sci. STKE 2004, pe17 (2004).
-
(2004)
Sci. STKE
-
-
Tsang, M.1
Dawid, I.B.2
-
32
-
-
18144423534
-
Structural basis for fibroblast growth factor receptor activation
-
Mohammadi, M., Olsen, S.K. & Ibrahimi, O.A. Structural basis for fibroblast growth factor receptor activation. Cytokine Growth Factor Rev. 16, 107-137 (2005).
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 107-137
-
-
Mohammadi, M.1
Olsen, S.K.2
Ibrahimi, O.A.3
-
33
-
-
0026502460
-
Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells
-
Ornitz, D.M. et al. Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol. Cell. Biol. 12, 240-247 (1992).
-
(1992)
Mol. Cell. Biol
, vol.12
, pp. 240-247
-
-
Ornitz, D.M.1
-
34
-
-
0033514915
-
Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans
-
Venkataraman, G., Shriver, Z., Davis, J.C. & Sasisekharan, R. Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans. Proc. Natl. Acad. Sci. USA 96, 1892-1897 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1892-1897
-
-
Venkataraman, G.1
Shriver, Z.2
Davis, J.C.3
Sasisekharan, R.4
-
35
-
-
0025004284
-
Murine developmental control genes
-
Kessel, M. & Gruss, P. Murine developmental control genes. Science 249, 374-379 (1990).
-
(1990)
Science
, vol.249
, pp. 374-379
-
-
Kessel, M.1
Gruss, P.2
-
36
-
-
0025941823
-
Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid
-
Kessel, M. & Gruss, P. Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell 67, 89-104 (1991).
-
(1991)
Cell
, vol.67
, pp. 89-104
-
-
Kessel, M.1
Gruss, P.2
-
37
-
-
0041919542
-
Improved protein-ligand docking using GOLD
-
Verdonk, M.L., Cole, J.C., Hartshorn, M.J., Murray, C.W. & Taylor, R.D. Improved protein-ligand docking using GOLD. Proteins 52, 609-623 (2003).
-
(2003)
Proteins
, vol.52
, pp. 609-623
-
-
Verdonk, M.L.1
Cole, J.C.2
Hartshorn, M.J.3
Murray, C.W.4
Taylor, R.D.5
-
38
-
-
0004016501
-
Comparison of simple potential functions for simulating liquid water
-
Jorgensen, W.L., Chandrasekhar, J., Madura, J.D., Impey, R.W. & Klein, M.L. Comparison of simple potential functions for simulating liquid water. J. Chem. Phys. 79, 926-935 (1983).
-
(1983)
J. Chem. Phys
, vol.79
, pp. 926-935
-
-
Jorgensen, W.L.1
Chandrasekhar, J.2
Madura, J.D.3
Impey, R.W.4
Klein, M.L.5
-
39
-
-
61349156281
-
-
Case, D.A. et al. AMBER 8 (University of California, San Francisco, 2004).
-
Case, D.A. et al. AMBER 8 (University of California, San Francisco, 2004).
-
-
-
-
41
-
-
0242663237
-
A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations
-
Duan, Y. et al. A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations. J. Comput. Chem. 24, 1999-2012 (2003).
-
(2003)
J. Comput. Chem
, vol.24
, pp. 1999-2012
-
-
Duan, Y.1
-
42
-
-
0032466648
-
Continuum solvent studies of the stability of RNA hairpin loops and helices
-
Srinivasan, J., Miller, J., Kollma, P.A. & Case, D.A. Continuum solvent studies of the stability of RNA hairpin loops and helices. J. Biomol. Struct. Dyn. 16, 671-682 (1998).
-
(1998)
J. Biomol. Struct. Dyn
, vol.16
, pp. 671-682
-
-
Srinivasan, J.1
Miller, J.2
Kollma, P.A.3
Case, D.A.4
-
43
-
-
0023265819
-
Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors
-
Hughes, S.H., Greenhouse, J.J., Petropoulos, C.J. & Sutrave, P. Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors. J. Virol. 61, 3004-3012 (1987).
-
(1987)
J. Virol
, vol.61
, pp. 3004-3012
-
-
Hughes, S.H.1
Greenhouse, J.J.2
Petropoulos, C.J.3
Sutrave, P.4
|