The function of rho-associated kinases ROCK1 and ROCK2 in the pathogenesis of cardiovascular disease

Frontiers in Pharmacology

Volumn 6, Issue NOV, 2015, Pages

  Hartmann, Svenja ^a,b,c   Ridley, Anne J ^c   Lutz, Susanne ^a,b  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b German Center for Cardiovascular Research   (Germany)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cardiovascular disease; Fibrosis; Heart; Hypertrophy; Inhibitor; Rho kinase; ROCK; ROCK signaling

Indexed keywords

CASPASE 3; EZRIN; LIM KINASE; MOESIN; MYOSIN LIGHT CHAIN 2; PROTEIN ROCK1; PROTEIN ROCK2; RADIXIN; RHO KINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CARDIOVASCULAR DISEASE; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME SUBSTRATE; EXPERIMENTAL ANIMAL; EXPERIMENTAL MODEL; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HYPERTENSION; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

EID: 84949769682     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00276     Document Type: Review

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