Rnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure

Cell Death and Disease

Volumn 5, Issue 6, 2014, Pages

  Yue, X ^a   Yang, X ^a   Lin, X ^a   Yang, T ^a   Yi, X ^b   Dai, Y ^a   Guo, J ^c   Li, T ^c   Shi, J ^d   Wei, L ^d   Fan, G C ^e   Chen, C ^a   Chang, J ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^c HAINAN MEDICAL UNIVERSITY   (China)

^d INDIANA UNIVERSITY   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptotic cardiomyopathy; Heart failure; Rho family GTPase 3; Rho kinase signaling

Indexed keywords

CASPASE 3; FASUDIL; GUANOSINE TRIPHOSPHATASE; PHOSPHOTRANSFERASE; RHO ASSOCIATED COILED COIL KINASE 1; RHO FAMILY GUANOSINE TRIPHOSPHATASE 3; RHO KINASE; UNCLASSIFIED DRUG; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RND3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE DELETION; HAPLOINSUFFICIENCY; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE OVERLOAD; HEMODYNAMIC STRESS; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR; SIGNAL TRANSDUCTION; TRANSVERSE AORTIC CONSTRICTION; ANIMAL; CARDIAC MUSCLE; CARDIOMEGALY; GENETICS; HEMODYNAMICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS;

ANIMALS; APOPTOSIS; CARDIOMEGALY; HAPLOINSUFFICIENCY; HEART FAILURE; HEMODYNAMICS; HUMANS; MICE; MICE, KNOCKOUT; MYOCARDIUM; RHO GTP-BINDING PROTEINS; STRESS, PHYSIOLOGICAL;

EID: 84903776347     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.235     Document Type: Article

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