Rho-ROCK-LIMK-cofilin pathway regulates shear stress activation of sterol regulatory element binding proteins

Circulation Research

Volumn 92, Issue 12, 2003, Pages 1296-1304

  Lin, Tong ^a   Zeng, Lingfang ^a   Liu, Yi ^a   DeFea, Kathryn ^a   Schwartz, Martin A ^b   Chien, Shu ^c   Shyy, John Y J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Endothelial cells; Mechanotransduction; Rho; Shear stress; Sterol regulatory element binding proteins

Indexed keywords

COFILIN; DNA; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; LIM KINASE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RHO ASSOCIATED SERINE THREONINE KINASE; RHO FACTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL CELL; AORTA; ARTICLE; CATTLE; CELL CULTURE; CHOLESTEROL METABOLISM; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; ENZYME ASSAY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GOLGI COMPLEX; IMMUNOBLOTTING; NONHUMAN; PLASMID; PRIORITY JOURNAL; SHEAR STRESS; SIGNAL TRANSDUCTION;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ANIMALS; CATTLE; CCAAT-ENHANCER-BINDING PROTEINS; CELL ADHESION; CELLS, CULTURED; CHO CELLS; CRICETINAE; DNA-BINDING PROTEINS; ENDOTHELIUM, VASCULAR; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; MICROSCOPY, FLUORESCENCE; MUTATION; PLASMIDS; PROTEIN KINASES; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STRESS, MECHANICAL; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0037786965     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000078780.65824.8B     Document Type: Article

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