A major haplotype block at the rho-associated kinase 2 locus is associated with a lower risk of hypertension in a recessive manner: THe HYPGENE study

Hypertension Research

Volumn 31, Issue 8, 2008, Pages 1651-1657

  Rankinen, Tuomo ^a   Church, Timothy ^a   Rice, Treva ^b   Markward, Nathan ^a   Blair, Steven N ^c   Bouchard, Claude ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Haplotype block; Haplotype tagging single nucleotide polymorphisms; Hypertension; Linkage disequilibrium; Rho associated kinase 2

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GENOMIC DNA; RHO KINASE; RHO KINASE 2; UNCLASSIFIED DRUG;

ADULT; AGE; ARTICLE; BODY MASS; CARDIOPULMONARY FUNCTION; CAUCASIAN; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; HAPLOTYPE; HOMOZYGOTE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PROSPECTIVE STUDY; PROTEIN DOMAIN; RECESSIVE INHERITANCE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SMOOTH MUSCLE CONTRACTION; VASCULAR SMOOTH MUSCLE;

ADULT; COHORT STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENES, RECESSIVE; HAPLOTYPES; HUMANS; HYPERTENSION; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RHO-ASSOCIATED KINASES; RISK FACTORS;

EID: 55449105596     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.31.1651     Document Type: Article

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