Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the α 1-adrenergic positive inotropic effect in human atrium

Cardiovascular Research

Volumn 65, Issue 1, 2005, Pages 211-220

  Grimm, Michael ^a   Haas, Pascal ^a   Willipinski Stapelfeldt, Birthe ^a   Zimmermann, Wolfram Hubertus ^a   Rau, Thomas ^a   Pantel, Klaus ^a   Weyand, Michael ^b   Eschenhagen, Thomas ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Calcium sensitivity; Cardiac contractility; Human heart; Myosin light chain kinase; Wortmannin

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE; MYOSIN LIGHT CHAIN KINASE INHIBITOR; MYOSIN LIGHT CHAIN PHOSPHATASE; NADOLOL; PHENYLEPHRINE; WORTMANNIN;

ADULT; AGED; ALPHA ADRENERGIC STIMULATION; ARTICLE; BETA ADRENERGIC STIMULATION; CHILD; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROSTIMULATION; HEART ATRIUM CONTRACTION; HEART ATRIUM MUSCLE; HUMAN; HUMAN TISSUE; INOTROPISM; MUSCLE EXCITATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ADOLESCENT; ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ADULT; AGED; ANALYSIS OF VARIANCE; ANDROSTADIENES; AZEPINES; CARDIAC MYOSINS; CHILD; CHILD, PRESCHOOL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME INHIBITORS; FEMALE; HEART ATRIA; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; NADOLOL; NAPHTHALENES; PHENYLEPHRINE; PHOSPHORYLATION; PRAZOSIN; PROTEIN KINASE INHIBITORS; STIMULATION, CHEMICAL;

EID: 11144311152     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2004.09.019     Document Type: Article

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