-
1
-
-
0032502680
-
Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein β subunits and the yeast response regulator protein Skn7
-
Alberts AS, Bouquin N, Johnston LH and Treisman R (1998) Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein β subunits and the yeast response regulator protein Skn7. J Biol Chem 273:8616-8622.
-
(1998)
J Biol Chem
, vol.273
, pp. 8616-8622
-
-
Alberts, A.S.1
Bouquin, N.2
Johnston, L.H.3
Treisman, R.4
-
2
-
-
0031048791
-
Formation of actin stress fibers and focal adhesions enhanced by Rhokinase
-
Amano M, Chihara K, Kimura K, Fukata Y, Nakamura N, Matsuura Y and Kaibuchi K (1997) Formation of actin stress fibers and focal adhesions enhanced by Rhokinase. Science 275:1308-1311.
-
(1997)
Science
, vol.275
, pp. 1308-1311
-
-
Amano, M.1
Chihara, K.2
Kimura, K.3
Fukata, Y.4
Nakamura, N.5
Matsuura, Y.6
Kaibuchi, K.7
-
3
-
-
0030035043
-
Identification of a putative target for Rho as the serinethreonine kinase protein kinase N
-
Amano M, Mukai H, Ono Y, Chihara K, Matsui T, Hamajima Y, Okawa K, Iwamatsu A and Kaibuchi K (1996) Identification of a putative target for Rho as the serinethreonine kinase protein kinase N. Science 271:648-650.
-
(1996)
Science
, vol.271
, pp. 648-650
-
-
Amano, M.1
Mukai, H.2
Ono, Y.3
Chihara, K.4
Matsui, T.5
Hamajima, Y.6
Okawa, K.7
Iwamatsu, A.8
Kaibuchi, K.9
-
4
-
-
0031037187
-
A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos
-
Drechsel DN, Hyman AA, Hall A and Glotzer M (1997) A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos. Curr Biol 7:12-23.
-
(1997)
Curr Biol
, vol.7
, pp. 12-23
-
-
Drechsel, D.N.1
Hyman, A.A.2
Hall, A.3
Glotzer, M.4
-
6
-
-
15644378138
-
Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells
-
Hirai A, Nakamura S, Noguchi Y, Yasuda T, Kitagawa M, Tatsuno I, Oeda T, Tahara K, Terano T, Narumiya S, Kohn, LD and Saito Y (1997) Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells. J Biol Chem 272:13-16.
-
(1997)
J Biol Chem
, vol.272
, pp. 13-16
-
-
Hirai, A.1
Nakamura, S.2
Noguchi, Y.3
Yasuda, T.4
Kitagawa, M.5
Tatsuno, I.6
Oeda, T.7
Tahara, K.8
Terano, T.9
Narumiya, S.10
Kohn, L.D.11
Saito, Y.12
-
7
-
-
14444288533
-
Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells
-
Hirose M, Ishizaki T, Watanabe N, Uehata M, Kranenburg O, Moolenaar WH, Matsumura F, Maekawa M, Bito H and Narumiya S (1998) Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. J Cell Biol 141:1625-1636.
-
(1998)
J Cell Biol
, vol.141
, pp. 1625-1636
-
-
Hirose, M.1
Ishizaki, T.2
Watanabe, N.3
Uehata, M.4
Kranenburg, O.5
Moolenaar, W.H.6
Matsumura, F.7
Maekawa, M.8
Bito, H.9
Narumiya, S.10
-
8
-
-
9244220646
-
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
-
Ishizaki T, Maekawa M, Fujisawa K, Okawa K, Iwamatsu A, Fujita A, Watanabe N, Saito Y, Kakizuka A, Morii N and Narumiya S (1996) The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. EMBO J 15:1885-1893.
-
(1996)
EMBO J
, vol.15
, pp. 1885-1893
-
-
Ishizaki, T.1
Maekawa, M.2
Fujisawa, K.3
Okawa, K.4
Iwamatsu, A.5
Fujita, A.6
Watanabe, N.7
Saito, Y.8
Kakizuka, A.9
Morii, N.10
Narumiya, S.11
-
9
-
-
0030615004
-
p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions
-
Ishizaki T, Naito M, Fujisawa K, Maekawa M, Watanabe N, Saito Y and Narumiya S (1997) p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions. FEBS Lett 404:118-124.
-
(1997)
FEBS Lett
, vol.404
, pp. 118-124
-
-
Ishizaki, T.1
Naito, M.2
Fujisawa, K.3
Maekawa, M.4
Watanabe, N.5
Saito, Y.6
Narumiya, S.7
-
10
-
-
0032935495
-
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
-
Itoh K, Yoshioka K, Akedo H, Uehata M, Ishizaki T and Narumiya S (1999) An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat Med 5:221-225.
-
(1999)
Nat Med
, vol.5
, pp. 221-225
-
-
Itoh, K.1
Yoshioka, K.2
Akedo, H.3
Uehata, M.4
Ishizaki, T.5
Narumiya, S.6
-
11
-
-
9444242736
-
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
-
Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, Iwamatsu A and Kaibuchi K (1996) Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273:245-248.
-
(1996)
Science
, vol.273
, pp. 245-248
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
Chihara, K.4
Fukata, Y.5
Nakafuku, M.6
Yamamori, B.7
Feng, J.8
Nakano, T.9
Okawa, K.10
Iwamatsu, A.11
Kaibuchi, K.12
-
12
-
-
0027509362
-
Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI)
-
Kishi K, Sasaki T, Kuroda S, Itoh T and Takai Y (1993) Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI). J Cell Biol 120:1187-1195.
-
(1993)
J Cell Biol
, vol.120
, pp. 1187-1195
-
-
Kishi, K.1
Sasaki, T.2
Kuroda, S.3
Itoh, T.4
Takai, Y.5
-
13
-
-
0033593667
-
Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets
-
Klages B, Brandt U, Simon MI, Schultz G and Offermanns S (1999) Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets. J Cell Biol 144:745-754.
-
(1999)
J Cell Biol
, vol.144
, pp. 745-754
-
-
Klages, B.1
Brandt, U.2
Simon, M.I.3
Schultz, G.4
Offermanns, S.5
-
14
-
-
0033005291
-
The effects of the selective ROCK inhibitor, Y27632, on ET-1-induced hypertrophic response in neonatal rat cardiac myocytes: Possible involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy
-
Kuwahara K, Saito Y, Nakagawa O, Kishimoto I, Harada M, Ogawa E, Miyamoto Y, Hamanaka I, Kajiyama N, Takahashi N, Izumi T, Kawakami R, Tamura N, Ogawa Y and Nakao K (1999) The effects of the selective ROCK inhibitor, Y27632, on ET-1-induced hypertrophic response in neonatal rat cardiac myocytes: Possible involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy. FEBS Lett 452:314-318.
-
(1999)
FEBS Lett
, vol.452
, pp. 314-318
-
-
Kuwahara, K.1
Saito, Y.2
Nakagawa, O.3
Kishimoto, I.4
Harada, M.5
Ogawa, E.6
Miyamoto, Y.7
Hamanaka, I.8
Kajiyama, N.9
Takahashi, N.10
Izumi, T.11
Kawakami, R.12
Tamura, N.13
Ogawa, Y.14
Nakao, K.15
-
15
-
-
0029789678
-
The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton
-
Leung T, Chen XQ, Manser E and Lim L (1996) The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton. Mol Cell Biol 16:5313-5327.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5313-5327
-
-
Leung, T.1
Chen, X.Q.2
Manser, E.3
Lim, L.4
-
16
-
-
0028863142
-
A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes
-
Leung T, Manser E, Tan L and Lim L (1995) A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes. J Biol Chem 270:29051-29054.
-
(1995)
J Biol Chem
, vol.270
, pp. 29051-29054
-
-
Leung, T.1
Manser, E.2
Tan, L.3
Lim, L.4
-
17
-
-
0027691240
-
A rho-like protein is involved in the organization of the contractile ring in dividing sand dollar eggs
-
Mabuchi I, Hamaguchi Y. Fujimoto H, Morii N, Mishima M and Narumiya S (1993) A rho-like protein is involved in the organization of the contractile ring in dividing sand dollar eggs. Zygote 1:325-331.
-
(1993)
Zygote
, vol.1
, pp. 325-331
-
-
Mabuchi, I.1
Hamaguchi, Y.2
Fujimoto, H.3
Morii, N.4
Mishima, M.5
Narumiya, S.6
-
18
-
-
0032581530
-
Role of citron kinase as a target of the small GTPase Rho in cytokinesis
-
Madaule P, Eda M, Watanabe N, Fujisawa K, Matsuoka T, Bito H, Ishizaki T and Narumiya S (1998) Role of citron kinase as a target of the small GTPase Rho in cytokinesis. Nature 394:491-494.
-
(1998)
Nature
, vol.394
, pp. 491-494
-
-
Madaule, P.1
Eda, M.2
Watanabe, N.3
Fujisawa, K.4
Matsuoka, T.5
Bito, H.6
Ishizaki, T.7
Narumiya, S.8
-
19
-
-
0029559573
-
A novel partner for the GTP-bound forms of rho and rac
-
Madaule P, Furuyashiki T, Reid T, Ishizaki T, Watanabe G, Morii N and Narumiya S (1995) A novel partner for the GTP-bound forms of rho and rac. FEBS Lett 377:243-248.
-
(1995)
FEBS Lett
, vol.377
, pp. 243-248
-
-
Madaule, P.1
Furuyashiki, T.2
Reid, T.3
Ishizaki, T.4
Watanabe, G.5
Morii, N.6
Narumiya, S.7
-
20
-
-
9244257348
-
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
-
Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M, Nakano T, Okawa K, Iwamatsu A and Kaibuchi K (1996) Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J 15:2208-2216.
-
(1996)
EMBO J
, vol.15
, pp. 2208-2216
-
-
Matsui, T.1
Amano, M.2
Yamamoto, T.3
Chihara, K.4
Nakafuku, M.5
Ito, M.6
Nakano, T.7
Okawa, K.8
Iwamatsu, A.9
Kaibuchi, K.10
-
21
-
-
0032531929
-
Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain
-
Mohammadi M, Furoum S, Hamby JM, Schroeder MC, Panek RL, Lu GH, Eliseenkova AV, Green G, Schlessinger J and Hubbard SR (1998) Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain. EMBO J 17:5896-5904.
-
(1998)
EMBO J
, vol.17
, pp. 5896-5904
-
-
Mohammadi, M.1
Furoum, S.2
Hamby, J.M.3
Schroeder, M.C.4
Panek, R.L.5
Lu, G.H.6
Eliseenkova, A.V.7
Green, G.8
Schlessinger, J.9
Hubbard, S.R.10
-
22
-
-
0030945871
-
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
-
Mohammadi M, McMahon G, Sun L, Tang C, Hirth P, Yeh BK, Hubbard SR and Schlessinger J (1997) Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 276:955-960.
-
(1997)
Science
, vol.276
, pp. 955-960
-
-
Mohammadi, M.1
McMahon, G.2
Sun, L.3
Tang, C.4
Hirth, P.5
Yeh, B.K.6
Hubbard, S.R.7
Schlessinger, J.8
-
23
-
-
0030603119
-
ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice
-
Nakagawa O, Fujisawa K, Ishizaki T, Saito Y, Nakao K and Narumiya S (1996) ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice. FEBS Lett 392:189-193.
-
(1996)
FEBS Lett
, vol.392
, pp. 189-193
-
-
Nakagawa, O.1
Fujisawa, K.2
Ishizaki, T.3
Saito, Y.4
Nakao, K.5
Narumiya, S.6
-
24
-
-
0029791373
-
The small GTPase Rho: Cellular functions and signal transduction
-
Narumiya S (1996) The small GTPase Rho: Cellular functions and signal transduction. J Biochem 120:215-228.
-
(1996)
J Biochem
, vol.120
, pp. 215-228
-
-
Narumiya, S.1
-
25
-
-
0032991828
-
Rho-kinase in human neutrophils: A role in signalling for myosin light chain phosphorylation and cell migration
-
Niggli V (1999) Rho-kinase in human neutrophils: A role in signalling for myosin light chain phosphorylation and cell migration. FEBS Lett 445:69-72.
-
(1999)
FEBS Lett
, vol.445
, pp. 69-72
-
-
Niggli, V.1
-
26
-
-
0033118584
-
Role of Rho and Rho kinase in the activation of voltage-regulated anion channels in bovine endothelial cells
-
Nilius B, Voets T, Prenen J, Barth H, Aktories K, Kaibuchi K, Droogmans G and Eggermont J (1999) Role of Rho and Rho kinase in the activation of voltage-regulated anion channels in bovine endothelial cells. J Physiol 516:67-74.
-
(1999)
J Physiol
, vol.516
, pp. 67-74
-
-
Nilius, B.1
Voets, T.2
Prenen, J.3
Barth, H.4
Aktories, K.5
Kaibuchi, K.6
Droogmans, G.7
Eggermont, J.8
-
27
-
-
0033594123
-
Rho GTPases control polarity, protrusion, and adhesion during cell movement
-
Nobes CD and Hall A (1999) Rho GTPases control polarity, protrusion, and adhesion during cell movement. J Cell Biol 144:1235-1244.
-
(1999)
J Cell Biol
, vol.144
, pp. 1235-1244
-
-
Nobes, C.D.1
Hall, A.2
-
28
-
-
0029101360
-
An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1
-
Olson MF, Ashworth A and Hall A (1995) An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science 269:1270-1272.
-
(1995)
Science
, vol.269
, pp. 1270-1272
-
-
Olson, M.F.1
Ashworth, A.2
Hall, A.3
-
29
-
-
0032537819
-
Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1
-
Olson MF, Paterson HF and Marshall CJ (1998) Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1. Nature 394:295-299.
-
(1998)
Nature
, vol.394
, pp. 295-299
-
-
Olson, M.F.1
Paterson, H.F.2
Marshall, C.J.3
-
30
-
-
0033545354
-
Transformation mediated by RhoA requires activity of ROCK kinases. Curr
-
Sahai E, Ishizaki T, Narumiya S and Treisman R (1999) Transformation mediated by RhoA requires activity of ROCK kinases. Curr Biol 9:136-145.
-
(1999)
Biol
, vol.9
, pp. 136-145
-
-
Sahai, E.1
Ishizaki, T.2
Narumiya, S.3
Treisman, R.4
-
31
-
-
0033612371
-
Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration
-
Seasholtz TM, Majumdar M, Kaplan DD and Brown JH (1999) Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration. Cir Res 84:1186-1193.
-
(1999)
Cir Res
, vol.84
, pp. 1186-1193
-
-
Seasholtz, T.M.1
Majumdar, M.2
Kaplan, D.D.3
Brown, J.H.4
-
33
-
-
0033562781
-
Agonist-induced regulation of myosin phosphatase activity in human platelets through activation of Rho-kinase
-
Suzuki Y, Yamamoto M, Wada H, Ito M, Nakano T, Sasaki Y, Narumiya S, Shiku H and Nishikawa M (1999) Agonist-induced regulation of myosin phosphatase activity in human platelets through activation of Rho-kinase. Blood 93:3408-3417.
-
(1999)
Blood
, vol.93
, pp. 3408-3417
-
-
Suzuki, Y.1
Yamamoto, M.2
Wada, H.3
Ito, M.4
Nakano, T.5
Sasaki, Y.6
Narumiya, S.7
Shiku, H.8
Nishikawa, M.9
-
34
-
-
0028143584
-
Physiological concentrations of purines and pyrimidines
-
Traut TW (1994) Physiological concentrations of purines and pyrimidines. Mol Cell Biochem 140:1-22.
-
(1994)
Mol Cell Biochem
, vol.140
, pp. 1-22
-
-
Traut, T.W.1
-
35
-
-
0032854118
-
The structure-based design of ATP-site directed protein kinase inhibitors
-
Toledo LM, Lydon NB and Elbaum D (1999) The structure-based design of ATP-site directed protein kinase inhibitors. Curr Med Chem 6:775-805.
-
(1999)
Curr Med Chem
, vol.6
, pp. 775-805
-
-
Toledo, L.M.1
Lydon, N.B.2
Elbaum, D.3
-
36
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata M, Ishizaki T, Satoh H, Ono T, Kawahara T, Morishita T, Tamakawa H, Yamagami K, Inui J, Maekawa M and Narumiya S (1997) Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389:990-994.
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
Ono, T.4
Kawahara, T.5
Morishita, T.6
Tamakawa, H.7
Yamagami, K.8
Inui, J.9
Maekawa, M.10
Narumiya, S.11
-
37
-
-
0030911424
-
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin
-
Watanabe N, Madaule P, Reid T, Ishizaki T, Watanabe G, Kakizuka A, Saito Y, Nakao K, Jockusch BM and Narumiya S (1997) p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J 16:3044-3056.
-
(1997)
EMBO J
, vol.16
, pp. 3044-3056
-
-
Watanabe, N.1
Madaule, P.2
Reid, T.3
Ishizaki, T.4
Watanabe, G.5
Kakizuka, A.6
Saito, Y.7
Nakao, K.8
Jockusch, B.M.9
Narumiya, S.10
-
38
-
-
13344285358
-
Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho
-
Watanabe G, Saito Y, Madaule P, Ishizaki T, Fujisawa K, Morii N, Mukai H, Ono Y, Kakizuka A and Narumiya S (1996) Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho. Science 271:645-648.
-
(1996)
Science
, vol.271
, pp. 645-648
-
-
Watanabe, G.1
Saito, Y.2
Madaule, P.3
Ishizaki, T.4
Fujisawa, K.5
Morii, N.6
Mukai, H.7
Ono, Y.8
Kakizuka, A.9
Narumiya, S.10
-
39
-
-
0027280575
-
ADP-ribosylation of the rhoA gene product by botulimim C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle
-
Yamamoto M, Marui N, Sakai T, Morii N, Kozaki S, Ikai K, Imamura S and Narumiya S (1993) ADP-ribosylation of the rhoA gene product by botulimim C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle. Oncogene 8:1449-1455.
-
(1993)
Oncogene
, vol.8
, pp. 1449-1455
-
-
Yamamoto, M.1
Marui, N.2
Sakai, T.3
Morii, N.4
Kozaki, S.5
Ikai, K.6
Imamura, S.7
Narumiya, S.8
-
40
-
-
0032583123
-
Roles of Rho-associated kinase in cytokinesis; mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filaments
-
Yasui Y, Amano M, Nagata K, Inagaki N, Nakamura H, Saya H, Kaibuchi K and Inagaki M (1998) Roles of Rho-associated kinase in cytokinesis; mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filaments. J Cell Biol 143:1249-1258.
-
(1998)
J Cell Biol
, vol.143
, pp. 1249-1258
-
-
Yasui, Y.1
Amano, M.2
Nagata, K.3
Inagaki, N.4
Nakamura, H.5
Saya, H.6
Kaibuchi, K.7
Inagaki, M.8
|