-
1
-
-
0029157421
-
Distribution of the mammalian Stat gene family in mouse chromosomes
-
[1] Copeland, N.G., Gilbert, D.J., Schindler, C., Zhong, Z., Wen, Z., Darnell, J.E. Jr., et al. Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics 29 (1995), 225–228.
-
(1995)
Genomics
, vol.29
, pp. 225-228
-
-
Copeland, N.G.1
Gilbert, D.J.2
Schindler, C.3
Zhong, Z.4
Wen, Z.5
Darnell, J.E.6
-
2
-
-
0036108577
-
IFNs and STATs in innate immunity to microorganisms
-
[2] Decker, T., Stockinger, S., Karaghiosoff, M., Muller, M., Kovarik, P., IFNs and STATs in innate immunity to microorganisms. J. Clin. Invest. 109 (2002), 1271–1277.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1271-1277
-
-
Decker, T.1
Stockinger, S.2
Karaghiosoff, M.3
Muller, M.4
Kovarik, P.5
-
3
-
-
84865308028
-
Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes
-
[3] Boisson-Dupuis, S., Kong, X.F., Okada, S., Cypowyj, S., Puel, A., Abel, L., et al. Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes. Curr. Opin. Immunol. 24 (2012), 364–378.
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 364-378
-
-
Boisson-Dupuis, S.1
Kong, X.F.2
Okada, S.3
Cypowyj, S.4
Puel, A.5
Abel, L.6
-
4
-
-
77951025336
-
STAT1 and pathogens, not a friendly relationship
-
[4] Najjar, I., Fagard, R., STAT1 and pathogens, not a friendly relationship. Biochimie 92 (2010), 425–444.
-
(2010)
Biochimie
, vol.92
, pp. 425-444
-
-
Najjar, I.1
Fagard, R.2
-
5
-
-
84864124859
-
IL-12 family cytokines: immunological playmakers
-
[5] Vignali, D.A., Kuchroo, V.K., IL-12 family cytokines: immunological playmakers. Nat. Immunol. 13 (2012), 722–728.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 722-728
-
-
Vignali, D.A.1
Kuchroo, V.K.2
-
6
-
-
0034658024
-
Serine phosphorylation of STATs
-
[6] Decker, T., Kovarik, P., Serine phosphorylation of STATs. Oncogene 19 (2000), 2628–2637.
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
8
-
-
84901360937
-
STAT1beta is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity
-
[8] Semper, C., Leitner, N.R., Lassnig, C., Parrini, M., Mahlakoiv, T., Rammerstorfer, M., et al. STAT1beta is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity. Mol. Cell Biol. 34 (2014), 2235–2248.
-
(2014)
Mol. Cell Biol.
, vol.34
, pp. 2235-2248
-
-
Semper, C.1
Leitner, N.R.2
Lassnig, C.3
Parrini, M.4
Mahlakoiv, T.5
Rammerstorfer, M.6
-
9
-
-
78651481470
-
The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins
-
[9] Cheon, H., Yang, J., Stark, G.R., The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins. J. Interferon Cytokine Res. 31 (2011), 33–40.
-
(2011)
J. Interferon Cytokine Res.
, vol.31
, pp. 33-40
-
-
Cheon, H.1
Yang, J.2
Stark, G.R.3
-
10
-
-
0036470732
-
Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways
-
[10] Meyer, T., Begitt, A., Lodige, I., van Rossum, M., Vinkemeier, U., Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways. EMBO J. 21 (2002), 344–354.
-
(2002)
EMBO J.
, vol.21
, pp. 344-354
-
-
Meyer, T.1
Begitt, A.2
Lodige, I.3
van Rossum, M.4
Vinkemeier, U.5
-
11
-
-
79953881238
-
Signal transducers and activators of transcription-from cytokine signalling to cancer biology
-
[11] Santos, C.I., Costa-Pereira, A.P., Signal transducers and activators of transcription-from cytokine signalling to cancer biology. Biochim. Biophys. Acta 1816 (2011), 38–49.
-
(2011)
Biochim. Biophys. Acta
, vol.1816
, pp. 38-49
-
-
Santos, C.I.1
Costa-Pereira, A.P.2
-
12
-
-
33748308794
-
JAK signaling globally counteracts heterochromatic gene silencing
-
[12] Shi, S., Calhoun, H.C., Xia, F., Li, J., Le, L., Li, W.X., JAK signaling globally counteracts heterochromatic gene silencing. Nat. Genet. 38 (2006), 1071–1076.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1071-1076
-
-
Shi, S.1
Calhoun, H.C.2
Xia, F.3
Li, J.4
Le, L.5
Li, W.X.6
-
13
-
-
56049119340
-
Unphosphorylated STATs go nuclear
-
[13] Brown, S., Zeidler, M.P., Unphosphorylated STATs go nuclear. Curr. Opin. Genet. Dev. 18 (2008), 455–460.
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 455-460
-
-
Brown, S.1
Zeidler, M.P.2
-
14
-
-
0036055754
-
Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3
-
[14] Meyer, T., Gavenis, K., Vinkemeier, U., Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3. Exp. Cell Res. 272 (2002), 45–55.
-
(2002)
Exp. Cell Res.
, vol.272
, pp. 45-55
-
-
Meyer, T.1
Gavenis, K.2
Vinkemeier, U.3
-
15
-
-
84891523846
-
JAK-STAT in heterochromatin and genome stability
-
[15] Silver-Morse, L., Li, W.X., JAK-STAT in heterochromatin and genome stability. JAKSTAT, 2, 2013, e26090.
-
(2013)
JAKSTAT
, vol.2
, pp. e26090
-
-
Silver-Morse, L.1
Li, W.X.2
-
16
-
-
84920014416
-
Protein tyrosine phosphatases as wardens of STAT signaling
-
[16] Bohmer, F.D., Friedrich, K., Protein tyrosine phosphatases as wardens of STAT signaling. JAKSTAT, 3, 2014, e28087.
-
(2014)
JAKSTAT
, vol.3
, pp. e28087
-
-
Bohmer, F.D.1
Friedrich, K.2
-
17
-
-
52949090018
-
SOCS regulation of the JAK/STAT signalling pathway
-
[17] Croker, B.A., Kiu, H., Nicholson, S.E., SOCS regulation of the JAK/STAT signalling pathway. Semin. Cell Dev. Biol. 19 (2008), 414–422.
-
(2008)
Semin. Cell Dev. Biol.
, vol.19
, pp. 414-422
-
-
Croker, B.A.1
Kiu, H.2
Nicholson, S.E.3
-
18
-
-
84924265294
-
Dynamic control of type I IFN signalling by an integrated network of negative regulators
-
[18] Porritt, R.A., Hertzog, P.J., Dynamic control of type I IFN signalling by an integrated network of negative regulators. Trends Immunol. 36 (2015), 150–160.
-
(2015)
Trends Immunol.
, vol.36
, pp. 150-160
-
-
Porritt, R.A.1
Hertzog, P.J.2
-
19
-
-
84902589832
-
STATs get their move on
-
[19] Reich, N.C., STATs get their move on. JAKSTAT, 2, 2013, e27080.
-
(2013)
JAKSTAT
, vol.2
, pp. e27080
-
-
Reich, N.C.1
-
20
-
-
73649111322
-
PIAS proteins: pleiotropic interactors associated with SUMO
-
[20] Rytinki, M.M., Kaikkonen, S., Pehkonen, P., Jaaskelainen, T., Palvimo, J.J., PIAS proteins: pleiotropic interactors associated with SUMO. Cell Mol. Life Sci. 66 (2009), 3029–3041.
-
(2009)
Cell Mol. Life Sci.
, vol.66
, pp. 3029-3041
-
-
Rytinki, M.M.1
Kaikkonen, S.2
Pehkonen, P.3
Jaaskelainen, T.4
Palvimo, J.J.5
-
21
-
-
84921870596
-
Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kind
-
[21] Boisson, B., Quartier, P., Casanova, J.L., Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kind. Curr. Opin. Immunol. 32 (2015), 90–105.
-
(2015)
Curr. Opin. Immunol.
, vol.32
, pp. 90-105
-
-
Boisson, B.1
Quartier, P.2
Casanova, J.L.3
-
22
-
-
84859950150
-
Inborn errors of human JAKs and STATs
-
[22] Casanova, J.L., Holland, S.M., Notarangelo, L.D., Inborn errors of human JAKs and STATs. Immunity 36 (2012), 515–528.
-
(2012)
Immunity
, vol.36
, pp. 515-528
-
-
Casanova, J.L.1
Holland, S.M.2
Notarangelo, L.D.3
-
23
-
-
84880271158
-
Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma
-
[23] Gordziel, C., Bratsch, J., Moriggl, R., Knosel, T., Friedrich, K., Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma. Br. J. Cancer 109 (2013), 138–146.
-
(2013)
Br. J. Cancer
, vol.109
, pp. 138-146
-
-
Gordziel, C.1
Bratsch, J.2
Moriggl, R.3
Knosel, T.4
Friedrich, K.5
-
24
-
-
38449098731
-
The role of signal transducers and activators of transcription in colon cancer
-
[24] Klampfer, L., The role of signal transducers and activators of transcription in colon cancer. Front Biosci. 13 (2008), 2888–2899.
-
(2008)
Front Biosci.
, vol.13
, pp. 2888-2899
-
-
Klampfer, L.1
-
25
-
-
77953976583
-
Intratumoral T cell infiltration, MHC class I and STAT1 as biomarkers of good prognosis in colorectal cancer
-
[25] Simpson, J.A., Al-Attar, A., Watson, N.F., Scholefield, J.H., Ilyas, M., Durrant, L.G., Intratumoral T cell infiltration, MHC class I and STAT1 as biomarkers of good prognosis in colorectal cancer. Gut 59 (2010), 926–933.
-
(2010)
Gut
, vol.59
, pp. 926-933
-
-
Simpson, J.A.1
Al-Attar, A.2
Watson, N.F.3
Scholefield, J.H.4
Ilyas, M.5
Durrant, L.G.6
-
26
-
-
84872607437
-
JAK/STAT/SOCS-signaling pathway and colon and rectal cancer
-
[26] Slattery, M.L., Lundgreen, A., Kadlubar, S.A., Bondurant, K.L., Wolff, R.K., JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. Mol. Carcinog. 52 (2013), 155–166.
-
(2013)
Mol. Carcinog.
, vol.52
, pp. 155-166
-
-
Slattery, M.L.1
Lundgreen, A.2
Kadlubar, S.A.3
Bondurant, K.L.4
Wolff, R.K.5
-
27
-
-
84876215369
-
STAT1 negatively regulates hepatocellular carcinoma cell proliferation
-
[27] Chen, G., Wang, H., Xie, S., Ma, J., Wang, G., STAT1 negatively regulates hepatocellular carcinoma cell proliferation. Oncol. Rep. 29 (2013), 2303–2310.
-
(2013)
Oncol. Rep.
, vol.29
, pp. 2303-2310
-
-
Chen, G.1
Wang, H.2
Xie, S.3
Ma, J.4
Wang, G.5
-
28
-
-
84914674885
-
The clinical and biological significance of STAT1 in esophageal squamous cell carcinoma
-
[28] Zhang, Y., Molavi, O., Su, M., Lai, R., The clinical and biological significance of STAT1 in esophageal squamous cell carcinoma. BMC Cancer., 14, 2014, 791.
-
(2014)
BMC Cancer.
, vol.14
, pp. 791
-
-
Zhang, Y.1
Molavi, O.2
Su, M.3
Lai, R.4
-
29
-
-
84898462512
-
Differential expression of STAT1 and p21 proteins predicts pancreatic cancer progression and prognosis
-
[29] Sun, Y., Yang, S., Sun, N., Chen, J., Differential expression of STAT1 and p21 proteins predicts pancreatic cancer progression and prognosis. Pancreas 43 (2014), 619–623.
-
(2014)
Pancreas
, vol.43
, pp. 619-623
-
-
Sun, Y.1
Yang, S.2
Sun, N.3
Chen, J.4
-
30
-
-
84906958162
-
Analysis of gene expression profiles of soft tissue sarcoma using a combination of knowledge-based filtering with integration of multiple statistics
-
[30] Takahashi, A., Nakayama, R., Ishibashi, N., Doi, A., Ichinohe, R., Ikuyo, Y., et al. Analysis of gene expression profiles of soft tissue sarcoma using a combination of knowledge-based filtering with integration of multiple statistics. PLoS ONE, 9, 2014, e106801.
-
(2014)
PLoS ONE
, vol.9
, pp. e106801
-
-
Takahashi, A.1
Nakayama, R.2
Ishibashi, N.3
Doi, A.4
Ichinohe, R.5
Ikuyo, Y.6
-
31
-
-
84923105991
-
Metastatic melanoma cells evade immune detection by silencing STAT1
-
[31] Osborn, J.L., Greer, S.F., Metastatic melanoma cells evade immune detection by silencing STAT1. Int. J. Mol. Sci. 16 (2015), 4343–4361.
-
(2015)
Int. J. Mol. Sci.
, vol.16
, pp. 4343-4361
-
-
Osborn, J.L.1
Greer, S.F.2
-
32
-
-
0036793979
-
Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer
-
[32] Widschwendter, A., Tonko-Geymayer, S., Welte, T., Daxenbichler, G., Marth, C., Doppler, W., Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer. Clin. Cancer Res. 8 (2002), 3065–3074.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3065-3074
-
-
Widschwendter, A.1
Tonko-Geymayer, S.2
Welte, T.3
Daxenbichler, G.4
Marth, C.5
Doppler, W.6
-
33
-
-
84899472350
-
High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer
-
[33] Tymoszuk, P., Charoentong, P., Hackl, H., Spilka, R., Muller-Holzner, E., Trajanoski, Z., et al. High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer. BMC Cancer, 14, 2014, 257.
-
(2014)
BMC Cancer
, vol.14
, pp. 257
-
-
Tymoszuk, P.1
Charoentong, P.2
Hackl, H.3
Spilka, R.4
Muller-Holzner, E.5
Trajanoski, Z.6
-
34
-
-
34547742663
-
Signal transducer and activator of transcription 1 in breast cancer: analysis with tissue microarray
-
[34] Sheen-Chen, S.M., Huang, C.C., Tang, R.P., Yang, C.H., Chou, F.F., Eng, H.L., Signal transducer and activator of transcription 1 in breast cancer: analysis with tissue microarray. Anticancer Res. 27 (2007), 2481–2486.
-
(2007)
Anticancer Res.
, vol.27
, pp. 2481-2486
-
-
Sheen-Chen, S.M.1
Huang, C.C.2
Tang, R.P.3
Yang, C.H.4
Chou, F.F.5
Eng, H.L.6
-
35
-
-
84856010212
-
STAT1-deficient mice spontaneously develop estrogen receptor alpha-positive luminal mammary carcinomas
-
[35] Chan, S.R., Vermi, W., Luo, J., Lucini, L., Rickert, C., Fowler, A.M., et al. STAT1-deficient mice spontaneously develop estrogen receptor alpha-positive luminal mammary carcinomas. Breast Cancer Res., 14, 2012, R16.
-
(2012)
Breast Cancer Res.
, vol.14
, pp. R16
-
-
Chan, S.R.1
Vermi, W.2
Luo, J.3
Lucini, L.4
Rickert, C.5
Fowler, A.M.6
-
36
-
-
79960854106
-
Differential methylation hybridization profiling identifies involvement of STAT1-mediated pathways in breast cancer
-
[36] Kim, J.H., Kang, H.S., Kim, T.W., Kim, S.J., Differential methylation hybridization profiling identifies involvement of STAT1-mediated pathways in breast cancer. Int. J. Oncol. 39 (2011), 955–963.
-
(2011)
Int. J. Oncol.
, vol.39
, pp. 955-963
-
-
Kim, J.H.1
Kang, H.S.2
Kim, T.W.3
Kim, S.J.4
-
37
-
-
78449258706
-
Loss of STAT1 from mouse mammary epithelium results in an increased Neu-induced tumor burden
-
[37] Klover, P.J., Muller, W.J., Robinson, G.W., Pfeiffer, R.M., Yamaji, D., Hennighausen, L., Loss of STAT1 from mouse mammary epithelium results in an increased Neu-induced tumor burden. Neoplasia 12 (2010), 899–905.
-
(2010)
Neoplasia
, vol.12
, pp. 899-905
-
-
Klover, P.J.1
Muller, W.J.2
Robinson, G.W.3
Pfeiffer, R.M.4
Yamaji, D.5
Hennighausen, L.6
-
38
-
-
79952344515
-
Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation
-
[38] Raven, J.F., Williams, V., Wang, S., Tremblay, M.L., Muller, W.J., Durbin, J.E., et al. Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation. Cell Cycle 10 (2011), 794–804.
-
(2011)
Cell Cycle
, vol.10
, pp. 794-804
-
-
Raven, J.F.1
Williams, V.2
Wang, S.3
Tremblay, M.L.4
Muller, W.J.5
Durbin, J.E.6
-
39
-
-
84862980088
-
Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias
-
[39] Schneckenleithner, C., Bago-Horvath, Z., Dolznig, H., Neugebauer, N., Kollmann, K., Kolbe, T., et al. Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias. Oncotarget 2 (2011), 1043–1054.
-
(2011)
Oncotarget
, vol.2
, pp. 1043-1054
-
-
Schneckenleithner, C.1
Bago-Horvath, Z.2
Dolznig, H.3
Neugebauer, N.4
Kollmann, K.5
Kolbe, T.6
-
40
-
-
84922093394
-
Role of STAT1 in the breast
-
[40] Bailey, S.G., Cragg, M.S., Townsend, P.A., Role of STAT1 in the breast. JAKSTAT 1 (2012), 197–199.
-
(2012)
JAKSTAT
, vol.1
, pp. 197-199
-
-
Bailey, S.G.1
Cragg, M.S.2
Townsend, P.A.3
-
41
-
-
84898910134
-
The tumor suppressor function of STAT1 in breast cancer
-
[41] Koromilas, A.E., Sexl, V., The tumor suppressor function of STAT1 in breast cancer. JAKSTAT, 2, 2013, e23353.
-
(2013)
JAKSTAT
, vol.2
, pp. e23353
-
-
Koromilas, A.E.1
Sexl, V.2
-
42
-
-
0032560475
-
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
-
[42] Kaplan, D.H., Shankaran, V., Dighe, A.S., Stockert, E., Aguet, M., Old, L.J., et al. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc. Natl. Acad. Sci. USA 95 (1998), 7556–7561.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7556-7561
-
-
Kaplan, D.H.1
Shankaran, V.2
Dighe, A.S.3
Stockert, E.4
Aguet, M.5
Old, L.J.6
-
43
-
-
0035142665
-
Activation of STAT proteins and growth control
-
[43] Bromberg, J.F., Activation of STAT proteins and growth control. BioEssays 23 (2001), 161–169.
-
(2001)
BioEssays
, vol.23
, pp. 161-169
-
-
Bromberg, J.F.1
-
44
-
-
0029799912
-
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma
-
[44] Bromberg, J.F., Horvath, C.M., Wen, Z., Schreiber, R.D., Darnell, J.E. Jr., Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc. Natl. Acad. Sci. USA 93 (1996), 7673–7678.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7673-7678
-
-
Bromberg, J.F.1
Horvath, C.M.2
Wen, Z.3
Schreiber, R.D.4
Darnell, J.E.5
-
45
-
-
33846202008
-
STAT1 as a key modulator of cell death
-
[45] Kim, H.S., Lee, M.S., STAT1 as a key modulator of cell death. Cell Signal 19 (2007), 454–465.
-
(2007)
Cell Signal
, vol.19
, pp. 454-465
-
-
Kim, H.S.1
Lee, M.S.2
-
46
-
-
84855568706
-
Interferon lambda: a new sword in cancer immunotherapy
-
[46] Lasfar, A., Abushahba, W., Balan, M., Cohen-Solal, K.A., Interferon lambda: a new sword in cancer immunotherapy. Clin. Dev. Immunol., 2011, 2011, 349575.
-
(2011)
Clin. Dev. Immunol.
, vol.2011
, pp. 349575
-
-
Lasfar, A.1
Abushahba, W.2
Balan, M.3
Cohen-Solal, K.A.4
-
47
-
-
0029923780
-
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1
-
[47] Chin, Y.E., Kitagawa, M., Su, W.C., You, Z.H., Iwamoto, Y., Fu, X.Y., Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 272 (1996), 719–722.
-
(1996)
Science
, vol.272
, pp. 719-722
-
-
Chin, Y.E.1
Kitagawa, M.2
Su, W.C.3
You, Z.H.4
Iwamoto, Y.5
Fu, X.Y.6
-
48
-
-
0032518668
-
Interferon-induces expression of cyclin-dependent kinase-inhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK)
-
[48] Mandal, M., Bandyopadhyay, D., Goepfert, T.M., Kumar, R., Interferon-induces expression of cyclin-dependent kinase-inhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK). Oncogene 16 (1998), 217–225.
-
(1998)
Oncogene
, vol.16
, pp. 217-225
-
-
Mandal, M.1
Bandyopadhyay, D.2
Goepfert, T.M.3
Kumar, R.4
-
49
-
-
0033403337
-
IFN-gamma induction of p21(WAF1) is required for cell cycle inhibition and suppression of apoptosis
-
[49] Hobeika, A.C., Etienne, W., Torres, B.A., Johnson, H.M., Subramaniam, P.S., IFN-gamma induction of p21(WAF1) is required for cell cycle inhibition and suppression of apoptosis. J. Interferon Cytokine Res. 19 (1999), 1351–1361.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 1351-1361
-
-
Hobeika, A.C.1
Etienne, W.2
Torres, B.A.3
Johnson, H.M.4
Subramaniam, P.S.5
-
50
-
-
58149374051
-
Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1
-
[50] Wang, S., Raven, J.F., Durbin, J.E., Koromilas, A.E., Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1. PLoS ONE, 3, 2008, e3476.
-
(2008)
PLoS ONE
, vol.3
, pp. e3476
-
-
Wang, S.1
Raven, J.F.2
Durbin, J.E.3
Koromilas, A.E.4
-
51
-
-
1442348077
-
Interferon-gamma-mediated growth regulation of melanoma cells: involvement of STAT1-dependent and STAT1-independent signals
-
[51] Kortylewski, M., Komyod, W., Kauffmann, M.E., Bosserhoff, A., Heinrich, P.C., Behrmann, I., Interferon-gamma-mediated growth regulation of melanoma cells: involvement of STAT1-dependent and STAT1-independent signals. J. Invest. Dermatol. 122 (2004), 414–422.
-
(2004)
J. Invest. Dermatol.
, vol.122
, pp. 414-422
-
-
Kortylewski, M.1
Komyod, W.2
Kauffmann, M.E.3
Bosserhoff, A.4
Heinrich, P.C.5
Behrmann, I.6
-
52
-
-
78650150534
-
STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest
-
[52] Dimco, G., Knight, R.A., Latchman, D.S., Stephanou, A., STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest. Cell Cycle 9 (2010), 4638–4649.
-
(2010)
Cell Cycle
, vol.9
, pp. 4638-4649
-
-
Dimco, G.1
Knight, R.A.2
Latchman, D.S.3
Stephanou, A.4
-
53
-
-
84897955968
-
Myc and cell cycle control
-
[53] Bretones, G., Delgado, M.D., Leon, J., Myc and cell cycle control. Biochim. Biophys. Acta 1849 (2015), 506–516.
-
(2015)
Biochim. Biophys. Acta
, vol.1849
, pp. 506-516
-
-
Bretones, G.1
Delgado, M.D.2
Leon, J.3
-
54
-
-
0034677195
-
Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways
-
[54] Ramana, C.V., Grammatikakis, N., Chernov, M., Nguyen, H., Goh, K.C., Williams, B.R., et al. Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways. EMBO J. 19 (2000), 263–272.
-
(2000)
EMBO J.
, vol.19
, pp. 263-272
-
-
Ramana, C.V.1
Grammatikakis, N.2
Chernov, M.3
Nguyen, H.4
Goh, K.C.5
Williams, B.R.6
-
55
-
-
84872107869
-
Interferon-gamma-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells
-
[55] Schmitt, M.J., Philippidou, D., Reinsbach, S.E., Margue, C., Wienecke-Baldacchino, A., Nashan, D., et al. Interferon-gamma-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells. Cell Commun. Signal, 10, 2012, 41.
-
(2012)
Cell Commun. Signal
, vol.10
, pp. 41
-
-
Schmitt, M.J.1
Philippidou, D.2
Reinsbach, S.E.3
Margue, C.4
Wienecke-Baldacchino, A.5
Nashan, D.6
-
56
-
-
0036716281
-
The Bcl2 family: regulators of the cellular life-or-death switch
-
[56] Cory, S., Adams, J.M., The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2 (2002), 647–656.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
57
-
-
0030985893
-
Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression
-
[57] Ossina, N.K., Cannas, A., Powers, V.C., Fitzpatrick, P.A., Knight, J.D., Gilbert, J.R., et al. Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression. J. Biol. Chem. 272 (1997), 16351–16357.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16351-16357
-
-
Ossina, N.K.1
Cannas, A.2
Powers, V.C.3
Fitzpatrick, P.A.4
Knight, J.D.5
Gilbert, J.R.6
-
58
-
-
0034616164
-
Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis
-
[58] Stephanou, A., Brar, B.K., Scarabelli, T.M., Jonassen, A.K., Yellon, D.M., Marber, M.S., et al. Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis. J. Biol. Chem. 275 (2000), 10002–10008.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10002-10008
-
-
Stephanou, A.1
Brar, B.K.2
Scarabelli, T.M.3
Jonassen, A.K.4
Yellon, D.M.5
Marber, M.S.6
-
59
-
-
84926444029
-
STAT1-mediated down-regulation of Bcl-2 expression is involved in IFN-gamma/TNF-alpha-induced apoptosis in NIT-1 cells
-
[59] Cao, Z.H., Zheng, Q.Y., Li, G.Q., Hu, X.B., Feng, S.L., Xu, G.L., et al. STAT1-mediated down-regulation of Bcl-2 expression is involved in IFN-gamma/TNF-alpha-induced apoptosis in NIT-1 cells. PLoS ONE, 10, 2015, e0120921.
-
(2015)
PLoS ONE
, vol.10
, pp. e0120921
-
-
Cao, Z.H.1
Zheng, Q.Y.2
Li, G.Q.3
Hu, X.B.4
Feng, S.L.5
Xu, G.L.6
-
60
-
-
0030788405
-
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis
-
[60] Chin, Y.E., Kitagawa, M., Kuida, K., Flavell, R.A., Fu, X.Y., Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol. Cell Biol. 17 (1997), 5328–5337.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 5328-5337
-
-
Chin, Y.E.1
Kitagawa, M.2
Kuida, K.3
Flavell, R.A.4
Fu, X.Y.5
-
61
-
-
0035216135
-
Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death
-
[61] Bernabei, P., Coccia, E.M., Rigamonti, L., Bosticardo, M., Forni, G., Pestka, S., et al. Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death. J. Leukoc. Biol. 70 (2001), 950–960.
-
(2001)
J. Leukoc. Biol.
, vol.70
, pp. 950-960
-
-
Bernabei, P.1
Coccia, E.M.2
Rigamonti, L.3
Bosticardo, M.4
Forni, G.5
Pestka, S.6
-
62
-
-
33745522118
-
Interferon-gamma induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors
-
[62] Egwuagu, C.E., Li, W., Yu, C.R., Che Mei Lin, M., Chan, C.C., Nakamura, T., et al. Interferon-gamma induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors. Oncogene 25 (2006), 3670–3679.
-
(2006)
Oncogene
, vol.25
, pp. 3670-3679
-
-
Egwuagu, C.E.1
Li, W.2
Yu, C.R.3
Che Mei Lin, M.4
Chan, C.C.5
Nakamura, T.6
-
63
-
-
30344462991
-
Interferon-alpha enhances TRAIL-mediated apoptosis by up-regulating caspase-8 transcription in human hepatoma cells
-
[63] Liedtke, C., Groger, N., Manns, M.P., Trautwein, C., Interferon-alpha enhances TRAIL-mediated apoptosis by up-regulating caspase-8 transcription in human hepatoma cells. J. Hepatol. 44 (2006), 342–349.
-
(2006)
J. Hepatol.
, vol.44
, pp. 342-349
-
-
Liedtke, C.1
Groger, N.2
Manns, M.P.3
Trautwein, C.4
-
64
-
-
0030659512
-
Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
-
[64] Kumar, A., Commane, M., Flickinger, T.W., Horvath, C.M., Stark, G.R., Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 278 (1997), 1630–1632.
-
(1997)
Science
, vol.278
, pp. 1630-1632
-
-
Kumar, A.1
Commane, M.2
Flickinger, T.W.3
Horvath, C.M.4
Stark, G.R.5
-
65
-
-
0035879751
-
IFN-gamma induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway
-
[65] Shin, E.C., Ahn, J.M., Kim, C.H., Choi, Y., Ahn, Y.S., Kim, H., et al. IFN-gamma induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway. Int. J. Cancer 93 (2001), 262–268.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 262-268
-
-
Shin, E.C.1
Ahn, J.M.2
Kim, C.H.3
Choi, Y.4
Ahn, Y.S.5
Kim, H.6
-
66
-
-
0032125574
-
IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression
-
[66] Xu, X., Fu, X.Y., Plate, J., Chong, A.S., IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression. Cancer Res. 58 (1998), 2832–2837.
-
(1998)
Cancer Res.
, vol.58
, pp. 2832-2837
-
-
Xu, X.1
Fu, X.Y.2
Plate, J.3
Chong, A.S.4
-
67
-
-
33845945377
-
TRAIL expression up-regulated by interferon-gamma via phosphorylation of STAT1 induces myeloma cell death
-
[67] Miura, Y., Tsujioka, T., Nishimura, Y., Sakaguchi, H., Maeda, M., Hayashi, H., et al. TRAIL expression up-regulated by interferon-gamma via phosphorylation of STAT1 induces myeloma cell death. Anticancer Res. 26 (2006), 4115–4124.
-
(2006)
Anticancer Res.
, vol.26
, pp. 4115-4124
-
-
Miura, Y.1
Tsujioka, T.2
Nishimura, Y.3
Sakaguchi, H.4
Maeda, M.5
Hayashi, H.6
-
68
-
-
0035862189
-
P53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma
-
[68] Meng, R.D., El-Deiry, W.S., P53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma. Exp. Cell Res. 262 (2001), 154–169.
-
(2001)
Exp. Cell Res.
, vol.262
, pp. 154-169
-
-
Meng, R.D.1
El-Deiry, W.S.2
-
69
-
-
0141816850
-
Stat1-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand and the cell-surface death signaling pathway by interferon beta in human cancer cells
-
[69] Choi, E.A., Lei, H., Maron, D.J., Wilson, J.M., Barsoum, J., Fraker, D.L., et al. Stat1-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand and the cell-surface death signaling pathway by interferon beta in human cancer cells. Cancer Res. 63 (2003), 5299–5307.
-
(2003)
Cancer Res.
, vol.63
, pp. 5299-5307
-
-
Choi, E.A.1
Lei, H.2
Maron, D.J.3
Wilson, J.M.4
Barsoum, J.5
Fraker, D.L.6
-
70
-
-
34748862622
-
Requirement of catalytically active Tyk2 and accessory signals for the induction of TRAIL mRNA by IFN-beta
-
[70] Rani, M.R., Pandalai, S., Shrock, J., Almasan, A., Ransohoff, R.M., Requirement of catalytically active Tyk2 and accessory signals for the induction of TRAIL mRNA by IFN-beta. J. Interferon Cytokine Res. 27 (2007), 767–779.
-
(2007)
J. Interferon Cytokine Res.
, vol.27
, pp. 767-779
-
-
Rani, M.R.1
Pandalai, S.2
Shrock, J.3
Almasan, A.4
Ransohoff, R.M.5
-
71
-
-
40649106576
-
Interferon-alpha induces TRAIL expression and cell death via an IRF-1-dependent mechanism in human bladder cancer cells
-
[71] Papageorgiou, A., Dinney, C.P., McConkey, D.J., Interferon-alpha induces TRAIL expression and cell death via an IRF-1-dependent mechanism in human bladder cancer cells. Cancer Biol. Ther. 6 (2007), 872–879.
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 872-879
-
-
Papageorgiou, A.1
Dinney, C.P.2
McConkey, D.J.3
-
72
-
-
0035926316
-
Involvement of TRAIL/TRAIL-R interaction in IFN-alpha-induced apoptosis of Daudi B lymphoma cells
-
[72] Oshima, K., Yanase, N., Ibukiyama, C., Yamashina, A., Kayagaki, N., Yagita, H., et al. Involvement of TRAIL/TRAIL-R interaction in IFN-alpha-induced apoptosis of Daudi B lymphoma cells. Cytokine 14 (2001), 193–201.
-
(2001)
Cytokine
, vol.14
, pp. 193-201
-
-
Oshima, K.1
Yanase, N.2
Ibukiyama, C.3
Yamashina, A.4
Kayagaki, N.5
Yagita, H.6
-
73
-
-
0035918171
-
Interferon gamma (IFNgamma) and tumor necrosis factor alpha synergism in ME-180 cervical cancer cell apoptosis and necrosis. IFNgamma inhibits cytoprotective NF-kappa B through STAT1/IRF-1 pathways
-
[73] Suk, K., Chang, I., Kim, Y.H., Kim, S., Kim, J.Y., Kim, H., et al. Interferon gamma (IFNgamma) and tumor necrosis factor alpha synergism in ME-180 cervical cancer cell apoptosis and necrosis. IFNgamma inhibits cytoprotective NF-kappa B through STAT1/IRF-1 pathways. J. Biol. Chem. 276 (2001), 13153–13159.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13153-13159
-
-
Suk, K.1
Chang, I.2
Kim, Y.H.3
Kim, S.4
Kim, J.Y.5
Kim, H.6
-
74
-
-
0037457482
-
Role of IRF-1 and caspase-7 in IFN-gamma enhancement of Fas-mediated apoptosis in ACHN renal cell carcinoma cells
-
[74] Tomita, Y., Bilim, V., Hara, N., Kasahara, T., Takahashi, K., Role of IRF-1 and caspase-7 in IFN-gamma enhancement of Fas-mediated apoptosis in ACHN renal cell carcinoma cells. Int. J. Cancer 104 (2003), 400–408.
-
(2003)
Int. J. Cancer
, vol.104
, pp. 400-408
-
-
Tomita, Y.1
Bilim, V.2
Hara, N.3
Kasahara, T.4
Takahashi, K.5
-
75
-
-
8544281698
-
STAT1: a modulator of chemotherapy-induced apoptosis
-
[75] Thomas, M., Finnegan, C.E., Rogers, K.M., Purcell, J.W., Trimble, A., Johnston, P.G., et al. STAT1: a modulator of chemotherapy-induced apoptosis. Cancer Res. 64 (2004), 8357–8364.
-
(2004)
Cancer Res.
, vol.64
, pp. 8357-8364
-
-
Thomas, M.1
Finnegan, C.E.2
Rogers, K.M.3
Purcell, J.W.4
Trimble, A.5
Johnston, P.G.6
-
76
-
-
39049180565
-
Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines
-
[76] Koike, K., Takaki, A., Tatsukawa, M., Suzuki, M., Shiraha, H., Iwasaki, Y., et al. Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines. Int. J. Oncol. 29 (2006), 1253–1261.
-
(2006)
Int. J. Oncol.
, vol.29
, pp. 1253-1261
-
-
Koike, K.1
Takaki, A.2
Tatsukawa, M.3
Suzuki, M.4
Shiraha, H.5
Iwasaki, Y.6
-
77
-
-
0037315472
-
Phase II trial of systemic continuous fluorouracil and subcutaneous recombinant interferon Alfa-2b for treatment of hepatocellular carcinoma
-
[77] Patt, Y.Z., Hassan, M.M., Lozano, R.D., Brown, T.D., Vauthey, J.N., Curley, S.A., et al. Phase II trial of systemic continuous fluorouracil and subcutaneous recombinant interferon Alfa-2b for treatment of hepatocellular carcinoma. J. Clin. Oncol. 21 (2003), 421–427.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 421-427
-
-
Patt, Y.Z.1
Hassan, M.M.2
Lozano, R.D.3
Brown, T.D.4
Vauthey, J.N.5
Curley, S.A.6
-
78
-
-
84962320363
-
Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest
-
[78] Acquavella, N., Clever, D., Yu, Z., Roelke-Parker, M., Palmer, D.C., Xi, L., et al. Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest. Cancer Immunol. Res. 3 (2015), 37–47.
-
(2015)
Cancer Immunol. Res.
, vol.3
, pp. 37-47
-
-
Acquavella, N.1
Clever, D.2
Yu, Z.3
Roelke-Parker, M.4
Palmer, D.C.5
Xi, L.6
-
79
-
-
4944261760
-
Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells
-
[79] Baran-Marszak, F., Feuillard, J., Najjar, I., Le Clorennec, C., Bechet, J.M., Dusanter-Fourt, I., et al. Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells. Blood 104 (2004), 2475–2483.
-
(2004)
Blood
, vol.104
, pp. 2475-2483
-
-
Baran-Marszak, F.1
Feuillard, J.2
Najjar, I.3
Le Clorennec, C.4
Bechet, J.M.5
Dusanter-Fourt, I.6
-
80
-
-
1242316989
-
STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis
-
[80] Townsend, P.A., Scarabelli, T.M., Davidson, S.M., Knight, R.A., Latchman, D.S., Stephanou, A., STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis. J. Biol. Chem. 279 (2004), 5811–5820.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5811-5820
-
-
Townsend, P.A.1
Scarabelli, T.M.2
Davidson, S.M.3
Knight, R.A.4
Latchman, D.S.5
Stephanou, A.6
-
81
-
-
85028113437
-
Translating p53 into the clinic
-
[81] Cheok, C.F., Verma, C.S., Baselga, J., Lane, D.P., Translating p53 into the clinic. Nat. Rev. Clin. Oncol. 8 (2011), 25–37.
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.8
, pp. 25-37
-
-
Cheok, C.F.1
Verma, C.S.2
Baselga, J.3
Lane, D.P.4
-
82
-
-
84935685694
-
TP53: an oncogene in disguise
-
[82] Soussi, T., Wiman, K.G., TP53: an oncogene in disguise. Cell Death Differ. 22 (2015), 1239–1249.
-
(2015)
Cell Death Differ.
, vol.22
, pp. 1239-1249
-
-
Soussi, T.1
Wiman, K.G.2
-
83
-
-
57149091187
-
Novel function of STAT1beta in B cells: induction of cell death by a mechanism different from that of STAT1alpha
-
[83] Najjar, I., Schischmanoff, P.O., Baran-Marszak, F., Deglesne, P.A., Youlyouz-Marfak, I., Pampin, M., et al. Novel function of STAT1beta in B cells: induction of cell death by a mechanism different from that of STAT1alpha. J. Leukoc. Biol. 84 (2008), 1604–1612.
-
(2008)
J. Leukoc. Biol.
, vol.84
, pp. 1604-1612
-
-
Najjar, I.1
Schischmanoff, P.O.2
Baran-Marszak, F.3
Deglesne, P.A.4
Youlyouz-Marfak, I.5
Pampin, M.6
-
84
-
-
0034130327
-
Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation
-
[84] Wang, Y., Wu, T.R., Cai, S., Welte, T., Chin, Y.E., Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation. Mol. Cell Biol. 20 (2000), 4505–4512.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 4505-4512
-
-
Wang, Y.1
Wu, T.R.2
Cai, S.3
Welte, T.4
Chin, Y.E.5
-
85
-
-
84894565195
-
Self-consumption: the interplay of autophagy and apoptosis
-
[85] Marino, G., Niso-Santano, M., Baehrecke, E.H., Kroemer, G., Self-consumption: the interplay of autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 15 (2014), 81–94.
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 81-94
-
-
Marino, G.1
Niso-Santano, M.2
Baehrecke, E.H.3
Kroemer, G.4
-
86
-
-
84861526009
-
Deconvoluting the context-dependent role for autophagy in cancer
-
[86] White, E., Deconvoluting the context-dependent role for autophagy in cancer. Nat. Rev. Cancer 12 (2012), 401–410.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 401-410
-
-
White, E.1
-
87
-
-
84865508002
-
Interferon-gamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1)
-
[87] Li, P., Du, Q., Cao, Z., Guo, Z., Evankovich, J., Yan, W., et al. Interferon-gamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1). Cancer Lett. 314 (2012), 213–222.
-
(2012)
Cancer Lett.
, vol.314
, pp. 213-222
-
-
Li, P.1
Du, Q.2
Cao, Z.3
Guo, Z.4
Evankovich, J.5
Yan, W.6
-
88
-
-
80052731707
-
Timing is critical for an effective anti-metastatic immunotherapy: the decisive role of IFNgamma/STAT1-mediated activation of autophagy
-
[88] Yan, J., Wang, Z.Y., Yang, H.Z., Liu, H.Z., Mi, S., Lv, X.X., et al. Timing is critical for an effective anti-metastatic immunotherapy: the decisive role of IFNgamma/STAT1-mediated activation of autophagy. PLoS One, 6, 2011, e24705.
-
(2011)
PLoS One
, vol.6
, pp. e24705
-
-
Yan, J.1
Wang, Z.Y.2
Yang, H.Z.3
Liu, H.Z.4
Mi, S.5
Lv, X.X.6
-
89
-
-
84894107349
-
New insights into cancer immunoediting and its three component phases–elimination, equilibrium and escape
-
[89] Mittal, D., Gubin, M.M., Schreiber, R.D., Smyth, M.J., New insights into cancer immunoediting and its three component phases–elimination, equilibrium and escape. Curr. Opin. Immunol. 27 (2014), 16–25.
-
(2014)
Curr. Opin. Immunol.
, vol.27
, pp. 16-25
-
-
Mittal, D.1
Gubin, M.M.2
Schreiber, R.D.3
Smyth, M.J.4
-
90
-
-
0032824424
-
Cutting edge: differentiation of antitumor CTL in vivo requires host expression of Stat1
-
[90] Fallarino, F., Gajewski, T.F., Cutting edge: differentiation of antitumor CTL in vivo requires host expression of Stat1. J. Immunol. 163 (1999), 4109–4113.
-
(1999)
J. Immunol.
, vol.163
, pp. 4109-4113
-
-
Fallarino, F.1
Gajewski, T.F.2
-
91
-
-
0034292328
-
Distinct requirements for IFNs and STAT1 in NK cell function
-
[91] Lee, C.K., Rao, D.T., Gertner, R., Gimeno, R., Frey, A.B., Levy, D.E., Distinct requirements for IFNs and STAT1 in NK cell function. J. Immunol. 165 (2000), 3571–3577.
-
(2000)
J. Immunol.
, vol.165
, pp. 3571-3577
-
-
Lee, C.K.1
Rao, D.T.2
Gertner, R.3
Gimeno, R.4
Frey, A.B.5
Levy, D.E.6
-
92
-
-
84881614850
-
CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance
-
[92] Putz, E.M., Gotthardt, D., Hoermann, G., Csiszar, A., Wirth, S., Berger, A., et al. CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance. Cell Rep. 4 (2013), 437–444.
-
(2013)
Cell Rep.
, vol.4
, pp. 437-444
-
-
Putz, E.M.1
Gotthardt, D.2
Hoermann, G.3
Csiszar, A.4
Wirth, S.5
Berger, A.6
-
93
-
-
15844371250
-
Direct effects of T-bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation
-
[93] Robbins, S.H., Tessmer, M.S., Van Kaer, L., Brossay, L., Direct effects of T-bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation. Eur. J. Immunol. 35 (2005), 757–765.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 757-765
-
-
Robbins, S.H.1
Tessmer, M.S.2
Van Kaer, L.3
Brossay, L.4
-
94
-
-
84885469133
-
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance
-
[94] Mizutani, T., Neugebauer, N., Putz, E.M., Moritz, N., Simma, O., Zebedin-Brandl, E., et al. Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance. Oncoimmunology 1 (2012), 1027–1037.
-
(2012)
Oncoimmunology
, vol.1
, pp. 1027-1037
-
-
Mizutani, T.1
Neugebauer, N.2
Putz, E.M.3
Moritz, N.4
Simma, O.5
Zebedin-Brandl, E.6
-
95
-
-
84941775673
-
Tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity
-
[95] Prchal-Murphy, M., Witalisz-Siepracka, A., Bednarik, K.T., Putz, E.M., Gotthardt, D., Meissl, K., et al. Tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity. Oncoimmunology, 4, 2015, e1047579.
-
(2015)
Oncoimmunology
, vol.4
, pp. e1047579
-
-
Prchal-Murphy, M.1
Witalisz-Siepracka, A.2
Bednarik, K.T.3
Putz, E.M.4
Gotthardt, D.5
Meissl, K.6
-
96
-
-
84867991737
-
Impairment of hepatic NK cell development in IFN-gamma deficient mice
-
[96] Wu, X., Chen, Y., Sun, R., Wei, H., Tian, Z., Impairment of hepatic NK cell development in IFN-gamma deficient mice. Cytokine 60 (2012), 616–625.
-
(2012)
Cytokine
, vol.60
, pp. 616-625
-
-
Wu, X.1
Chen, Y.2
Sun, R.3
Wei, H.4
Tian, Z.5
-
97
-
-
80355147292
-
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
-
[97] Diamond, M.S., Kinder, M., Matsushita, H., Mashayekhi, M., Dunn, G.P., Archambault, J.M., et al. Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J. Exp. Med. 208 (2011), 1989–2003.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1989-2003
-
-
Diamond, M.S.1
Kinder, M.2
Matsushita, H.3
Mashayekhi, M.4
Dunn, G.P.5
Archambault, J.M.6
-
98
-
-
80355136945
-
Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells
-
[98] Fuertes, M.B., Kacha, A.K., Kline, J., Woo, S.R., Kranz, D.M., Murphy, K.M., et al. Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells. J. Exp. Med. 208 (2011), 2005–2016.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2005-2016
-
-
Fuertes, M.B.1
Kacha, A.K.2
Kline, J.3
Woo, S.R.4
Kranz, D.M.5
Murphy, K.M.6
-
99
-
-
79953780211
-
Deficiency of activated STAT1 in head and neck cancer cells mediates TAP1-dependent escape from cytotoxic T lymphocytes
-
[99] Leibowitz, M.S., Andrade Filho, P.A., Ferrone, S., Ferris, R.L., Deficiency of activated STAT1 in head and neck cancer cells mediates TAP1-dependent escape from cytotoxic T lymphocytes. Cancer Immunol. Immunother. 60 (2011), 525–535.
-
(2011)
Cancer Immunol. Immunother.
, vol.60
, pp. 525-535
-
-
Leibowitz, M.S.1
Andrade Filho, P.A.2
Ferrone, S.3
Ferris, R.L.4
-
100
-
-
0033571762
-
Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes
-
[100] Lee, C.K., Gimeno, R., Levy, D.E., Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes. J. Exp. Med. 190 (1999), 1451–1464.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1451-1464
-
-
Lee, C.K.1
Gimeno, R.2
Levy, D.E.3
-
101
-
-
0035953308
-
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
-
[101] Shankaran, V., Ikeda, H., Bruce, A.T., White, J.M., Swanson, P.E., Old, L.J., et al. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410 (2001), 1107–1111.
-
(2001)
Nature
, vol.410
, pp. 1107-1111
-
-
Shankaran, V.1
Ikeda, H.2
Bruce, A.T.3
White, J.M.4
Swanson, P.E.5
Old, L.J.6
-
102
-
-
84874099238
-
SHP2 is overexpressed and inhibits pSTAT1-mediated APM component expression, T-cell attracting chemokine secretion, and CTL recognition in head and neck cancer cells
-
[102] Leibowitz, M.S., Srivastava, R.M., Andrade Filho, P.A., Egloff, A.M., Wang, L., Seethala, R.R., et al. SHP2 is overexpressed and inhibits pSTAT1-mediated APM component expression, T-cell attracting chemokine secretion, and CTL recognition in head and neck cancer cells. Clin. Cancer Res. 19 (2013), 798–808.
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 798-808
-
-
Leibowitz, M.S.1
Srivastava, R.M.2
Andrade Filho, P.A.3
Egloff, A.M.4
Wang, L.5
Seethala, R.R.6
-
103
-
-
70549112270
-
The angiogenic switch in carcinogenesis
-
[103] Baeriswyl, V., Christofori, G., The angiogenic switch in carcinogenesis. Semin. Cancer Biol. 19 (2009), 329–337.
-
(2009)
Semin. Cancer Biol.
, vol.19
, pp. 329-337
-
-
Baeriswyl, V.1
Christofori, G.2
-
104
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
[104] Bergers, G., Hanahan, D., Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer 8 (2008), 592–603.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
105
-
-
33645731313
-
Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis
-
[105] Battle, T.E., Lynch, R.A., Frank, D.A., Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis. Cancer Res. 66 (2006), 3649–3657.
-
(2006)
Cancer Res.
, vol.66
, pp. 3649-3657
-
-
Battle, T.E.1
Lynch, R.A.2
Frank, D.A.3
-
106
-
-
84881484241
-
IL-27 inhibits lymphatic endothelial cell proliferation by STAT1-regulated gene expression
-
[106] Nielsen, S.R., Hammer, T., Gibson, J., Pepper, M.S., Nisato, R.E., Dissing, S., et al. IL-27 inhibits lymphatic endothelial cell proliferation by STAT1-regulated gene expression. Microcirculation 20 (2013), 555–564.
-
(2013)
Microcirculation
, vol.20
, pp. 555-564
-
-
Nielsen, S.R.1
Hammer, T.2
Gibson, J.3
Pepper, M.S.4
Nisato, R.E.5
Dissing, S.6
-
107
-
-
84925760617
-
EphrinB2 controls vessel pruning through STAT1-JNK3 signalling
-
[107] Salvucci, O., Ohnuki, H., Maric, D., Hou, X., Li, X., Yoon, S.O., et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat. Commun., 6, 2015, 6576.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6576
-
-
Salvucci, O.1
Ohnuki, H.2
Maric, D.3
Hou, X.4
Li, X.5
Yoon, S.O.6
-
108
-
-
0037061736
-
Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells
-
[108] Huang, S., Bucana, C.D., Van Arsdall, M., Fidler, I.J., Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells. Oncogene 21 (2002), 2504–2512.
-
(2002)
Oncogene
, vol.21
, pp. 2504-2512
-
-
Huang, S.1
Bucana, C.D.2
Van Arsdall, M.3
Fidler, I.J.4
-
109
-
-
84888091506
-
IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer
-
[109] Kachroo, P., Lee, M.H., Zhang, L., Baratelli, F., Lee, G., Srivastava, M.K., et al. IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer. J. Exp. Clin. Cancer Res., 32, 2013, 97.
-
(2013)
J. Exp. Clin. Cancer Res.
, vol.32
, pp. 97
-
-
Kachroo, P.1
Lee, M.H.2
Zhang, L.3
Baratelli, F.4
Lee, G.5
Srivastava, M.K.6
-
110
-
-
2142825067
-
Progressive dysregulation of transcription factors NF-kappa B and STAT1 in prostate cancer cells causes proangiogenic production of CXC chemokines
-
[110] Shen, H., Lentsch, A.B., Progressive dysregulation of transcription factors NF-kappa B and STAT1 in prostate cancer cells causes proangiogenic production of CXC chemokines. Am. J. Physiol. Cell Physiol. 286 (2004), C840–C847.
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.286
, pp. C840-C847
-
-
Shen, H.1
Lentsch, A.B.2
-
111
-
-
68549083336
-
STAT1 represses hypoxia-inducible factor-1-mediated transcription
-
[111] Hiroi, M., Mori, K., Sakaeda, Y., Shimada, J., Ohmori, Y., STAT1 represses hypoxia-inducible factor-1-mediated transcription. Biochem. Biophys. Res. Commun. 387 (2009), 806–810.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.387
, pp. 806-810
-
-
Hiroi, M.1
Mori, K.2
Sakaeda, Y.3
Shimada, J.4
Ohmori, Y.5
-
112
-
-
0028923658
-
Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts
-
[112] Watson, C.J., Miller, W.R., Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts. Br. J. Cancer. 71 (1995), 840–844.
-
(1995)
Br. J. Cancer.
, vol.71
, pp. 840-844
-
-
Watson, C.J.1
Miller, W.R.2
-
113
-
-
84876921278
-
Tumor STAT1 transcription factor activity enhances breast tumor growth and immune suppression mediated by myeloid-derived suppressor cells
-
[113] Hix, L.M., Karavitis, J., Khan, M.W., Shi, Y.H., Khazaie, K., Zhang, M., Tumor STAT1 transcription factor activity enhances breast tumor growth and immune suppression mediated by myeloid-derived suppressor cells. J. Biol. Chem. 288 (2013), 11676–11688.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 11676-11688
-
-
Hix, L.M.1
Karavitis, J.2
Khan, M.W.3
Shi, Y.H.4
Khazaie, K.5
Zhang, M.6
-
114
-
-
84861347783
-
Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node metastasis in triple-negative breast cancer
-
[114] Greenwood, C., Metodieva, G., Al-Janabi, K., Lausen, B., Alldridge, L., Leng, L., et al. Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node metastasis in triple-negative breast cancer. J. Proteomics. 75 (2012), 3031–3040.
-
(2012)
J. Proteomics.
, vol.75
, pp. 3031-3040
-
-
Greenwood, C.1
Metodieva, G.2
Al-Janabi, K.3
Lausen, B.4
Alldridge, L.5
Leng, L.6
-
115
-
-
84866381896
-
Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance
-
[115] Zimmerman, M.A., Rahman, N.T., Yang, D., Lahat, G., Lazar, A.J., Pollock, R.E., et al. Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance. Cancer Res. 72 (2012), 4724–4732.
-
(2012)
Cancer Res.
, vol.72
, pp. 4724-4732
-
-
Zimmerman, M.A.1
Rahman, N.T.2
Yang, D.3
Lahat, G.4
Lazar, A.J.5
Pollock, R.E.6
-
116
-
-
84881434842
-
Periostin cooperates with mutant p53 to mediate invasion through the induction of STAT1 signaling in the esophageal tumor microenvironment
-
[116] Wong, G.S., Lee, J.S., Park, Y.Y., Klein-Szanto, A.J., Waldron, T.J., Cukierman, E., et al. Periostin cooperates with mutant p53 to mediate invasion through the induction of STAT1 signaling in the esophageal tumor microenvironment. Oncogenesis, 2, 2013, e59.
-
(2013)
Oncogenesis
, vol.2
, pp. e59
-
-
Wong, G.S.1
Lee, J.S.2
Park, Y.Y.3
Klein-Szanto, A.J.4
Waldron, T.J.5
Cukierman, E.6
-
117
-
-
84899629693
-
ARF and p53 coordinate tumor suppression of an oncogenic IFN-beta-STAT1-ISG15 signaling axis
-
[117] Forys, J.T., Kuzmicki, C.E., Saporita, A.J., Winkeler, C.L., Maggi, L.B. Jr., Weber, J.D., ARF and p53 coordinate tumor suppression of an oncogenic IFN-beta-STAT1-ISG15 signaling axis. Cell Rep. 7 (2014), 514–526.
-
(2014)
Cell Rep.
, vol.7
, pp. 514-526
-
-
Forys, J.T.1
Kuzmicki, C.E.2
Saporita, A.J.3
Winkeler, C.L.4
Maggi, L.B.5
Weber, J.D.6
-
118
-
-
84882377114
-
Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation
-
[118] Malilas, W., Koh, S.S., Kim, S., Srisuttee, R., Cho, I.R., Moon, J., et al. Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation. Int. J. Oncol. 43 (2013), 1111–1116.
-
(2013)
Int. J. Oncol.
, vol.43
, pp. 1111-1116
-
-
Malilas, W.1
Koh, S.S.2
Kim, S.3
Srisuttee, R.4
Cho, I.R.5
Moon, J.6
-
119
-
-
76849109309
-
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer
-
[119] Khodarev, N., Ahmad, R., Rajabi, H., Pitroda, S., Kufe, T., McClary, C., et al. Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. Oncogene 29 (2010), 920–929.
-
(2010)
Oncogene
, vol.29
, pp. 920-929
-
-
Khodarev, N.1
Ahmad, R.2
Rajabi, H.3
Pitroda, S.4
Kufe, T.5
McClary, C.6
-
120
-
-
70450247207
-
Mucins in cancer: function, prognosis and therapy
-
[120] Kufe, D.W., Mucins in cancer: function, prognosis and therapy. Nat. Rev. Cancer 9 (2009), 874–885.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 874-885
-
-
Kufe, D.W.1
-
121
-
-
26944443139
-
Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways
-
[121] Andrianifahanana, M., Agrawal, A., Singh, A.P., Moniaux, N., van Seuningen, I., Aubert, J.P., et al. Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways. Oncogene 24 (2005), 6143–6154.
-
(2005)
Oncogene
, vol.24
, pp. 6143-6154
-
-
Andrianifahanana, M.1
Agrawal, A.2
Singh, A.P.3
Moniaux, N.4
van Seuningen, I.5
Aubert, J.P.6
-
122
-
-
36049005541
-
IFN-gamma-induced expression of MUC4 in pancreatic cancer cells is mediated by STAT-1 upregulation: a novel mechanism for IFN-gamma response
-
[122] Andrianifahanana, M., Singh, A.P., Nemos, C., Ponnusamy, M.P., Moniaux, N., Mehta, P.P., et al. IFN-gamma-induced expression of MUC4 in pancreatic cancer cells is mediated by STAT-1 upregulation: a novel mechanism for IFN-gamma response. Oncogene 26 (2007), 7251–7261.
-
(2007)
Oncogene
, vol.26
, pp. 7251-7261
-
-
Andrianifahanana, M.1
Singh, A.P.2
Nemos, C.3
Ponnusamy, M.P.4
Moniaux, N.5
Mehta, P.P.6
-
123
-
-
84925002884
-
Targeting EGF-receptor(s) – STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer
-
[123] Seshacharyulu, P., Ponnusamy, M.P., Rachagani, S., Lakshmanan, I., Haridas, D., Yan, Y., et al. Targeting EGF-receptor(s) – STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer. Oncotarget 6 (2015), 5164–5181.
-
(2015)
Oncotarget
, vol.6
, pp. 5164-5181
-
-
Seshacharyulu, P.1
Ponnusamy, M.P.2
Rachagani, S.3
Lakshmanan, I.4
Haridas, D.5
Yan, Y.6
-
124
-
-
17044366637
-
STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion
-
[124] Kusmartsev, S., Gabrilovich, D.I., STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion. J. Immunol. 174 (2005), 4880–4891.
-
(2005)
J. Immunol.
, vol.174
, pp. 4880-4891
-
-
Kusmartsev, S.1
Gabrilovich, D.I.2
-
125
-
-
33845964143
-
The presence of STAT1-positive tumor-associated macrophages and their relation to outcome in patients with follicular lymphoma
-
[125] Alvaro, T., Lejeune, M., Camacho, F.I., Salvado, M.T., Sanchez, L., Garcia, J.F., et al. The presence of STAT1-positive tumor-associated macrophages and their relation to outcome in patients with follicular lymphoma. Haematologica 91 (2006), 1605–1612.
-
(2006)
Haematologica
, vol.91
, pp. 1605-1612
-
-
Alvaro, T.1
Lejeune, M.2
Camacho, F.I.3
Salvado, M.T.4
Sanchez, L.5
Garcia, J.F.6
-
126
-
-
84940826256
-
Interferon-gamma-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression
-
[126] Bellucci, R., Martin, A., Bommarito, D., Wang, K., Hansen, S.H., Freeman, G.J., et al. Interferon-gamma-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression. Oncoimmunology, 4, 2015, e1008824.
-
(2015)
Oncoimmunology
, vol.4
, pp. e1008824
-
-
Bellucci, R.1
Martin, A.2
Bommarito, D.3
Wang, K.4
Hansen, S.H.5
Freeman, G.J.6
-
127
-
-
34347400169
-
Plasma cells from multiple myeloma patients express B7–H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway
-
[127] Liu, J., Hamrouni, A., Wolowiec, D., Coiteux, V., Kuliczkowski, K., Hetuin, D., et al. Plasma cells from multiple myeloma patients express B7–H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway. Blood 110 (2007), 296–304.
-
(2007)
Blood
, vol.110
, pp. 296-304
-
-
Liu, J.1
Hamrouni, A.2
Wolowiec, D.3
Coiteux, V.4
Kuliczkowski, K.5
Hetuin, D.6
-
128
-
-
0038302927
-
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
-
[128] Loke, P., Allison, J.P., PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells. Proc. Natl. Acad. Sci. USA 100 (2003), 5336–5341.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5336-5341
-
-
Loke, P.1
Allison, J.P.2
-
129
-
-
84878592257
-
Gain-of-function STAT1 mutations are associated with PD-L1 overexpression and a defect in B-cell survival
-
[129] Romberg, N., Morbach, H., Lawrence, M.G., Kim, S., Kang, I., Holland, S.M., et al. Gain-of-function STAT1 mutations are associated with PD-L1 overexpression and a defect in B-cell survival. J. Allergy Clin. Immunol. 131 (2013), 1691–1693.
-
(2013)
J. Allergy Clin. Immunol.
, vol.131
, pp. 1691-1693
-
-
Romberg, N.1
Morbach, H.2
Lawrence, M.G.3
Kim, S.4
Kang, I.5
Holland, S.M.6
-
130
-
-
33745727118
-
STAT1 acts as a tumor promoter for leukemia development
-
[130] Kovacic, B., Stoiber, D., Moriggl, R., Weisz, E., Ott, R.G., Kreibich, R., et al. STAT1 acts as a tumor promoter for leukemia development. Cancer Cell 10 (2006), 77–87.
-
(2006)
Cancer Cell
, vol.10
, pp. 77-87
-
-
Kovacic, B.1
Stoiber, D.2
Moriggl, R.3
Weisz, E.4
Ott, R.G.5
Kreibich, R.6
-
131
-
-
84885476083
-
Modulation of antitumour immune responses by intratumoural Stat1 expression
-
[131] Messina, N.L., Banks, K.M., Vidacs, E., Martin, B.P., Long, F., Christiansen, A.J., et al. Modulation of antitumour immune responses by intratumoural Stat1 expression. Immunol. Cell Biol. 91 (2013), 556–567.
-
(2013)
Immunol. Cell Biol.
, vol.91
, pp. 556-567
-
-
Messina, N.L.1
Banks, K.M.2
Vidacs, E.3
Martin, B.P.4
Long, F.5
Christiansen, A.J.6
-
132
-
-
1242319531
-
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells
-
[132] Khodarev, N.N., Beckett, M., Labay, E., Darga, T., Roizman, B., Weichselbaum, R.R., STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc. Natl. Acad. Sci. USA 101 (2004), 1714–1719.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1714-1719
-
-
Khodarev, N.N.1
Beckett, M.2
Labay, E.3
Darga, T.4
Roizman, B.5
Weichselbaum, R.R.6
-
133
-
-
35148879113
-
Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells
-
[133] Khodarev, N.N., Minn, A.J., Efimova, E.V., Darga, T.E., Labay, E., Beckett, M., et al. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res. 67 (2007), 9214–9220.
-
(2007)
Cancer Res.
, vol.67
, pp. 9214-9220
-
-
Khodarev, N.N.1
Minn, A.J.2
Efimova, E.V.3
Darga, T.E.4
Labay, E.5
Beckett, M.6
-
134
-
-
34248545443
-
Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation
-
[134] Tsai, M.H., Cook, J.A., Chandramouli, G.V., DeGraff, W., Yan, H., Zhao, S., et al. Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation. Cancer Res. 67 (2007), 3845–3852.
-
(2007)
Cancer Res.
, vol.67
, pp. 3845-3852
-
-
Tsai, M.H.1
Cook, J.A.2
Chandramouli, G.V.3
DeGraff, W.4
Yan, H.5
Zhao, S.6
-
135
-
-
84855368868
-
Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner
-
[135] Duarte, C.W., Willey, C.D., Zhi, D., Cui, X., Harris, J.J., Vaughan, L.K., et al. Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner. PLoS One, 7, 2012, e29653.
-
(2012)
PLoS One
, vol.7
, pp. e29653
-
-
Duarte, C.W.1
Willey, C.D.2
Zhi, D.3
Cui, X.4
Harris, J.J.5
Vaughan, L.K.6
-
136
-
-
57449088412
-
An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
-
[136] Weichselbaum, R.R., Ishwaran, H., Yoon, T., Nuyten, D.S., Baker, S.W., Khodarev, N., et al. An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc. Natl. Acad. Sci. USA 105 (2008), 18490–18495.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18490-18495
-
-
Weichselbaum, R.R.1
Ishwaran, H.2
Yoon, T.3
Nuyten, D.S.4
Baker, S.W.5
Khodarev, N.6
-
137
-
-
84861790681
-
Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth
-
[137] Khodarev, N.N., Roizman, B., Weichselbaum, R.R., Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth. Clin. Cancer Res. 18 (2012), 3015–3021.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 3015-3021
-
-
Khodarev, N.N.1
Roizman, B.2
Weichselbaum, R.R.3
-
138
-
-
84908275360
-
Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
-
[138] Boelens, M.C., Wu, T.J., Nabet, B.Y., Xu, B., Qiu, Y., Yoon, T., et al. Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell 159 (2014), 499–513.
-
(2014)
Cell
, vol.159
, pp. 499-513
-
-
Boelens, M.C.1
Wu, T.J.2
Nabet, B.Y.3
Xu, B.4
Qiu, Y.5
Yoon, T.6
-
139
-
-
79959895071
-
HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer
-
[139] Stronach, E.A., Alfraidi, A., Rama, N., Datler, C., Studd, J.B., Agarwal, R., et al. HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer. Cancer Res. 71 (2011), 4412–4422.
-
(2011)
Cancer Res.
, vol.71
, pp. 4412-4422
-
-
Stronach, E.A.1
Alfraidi, A.2
Rama, N.3
Datler, C.4
Studd, J.B.5
Agarwal, R.6
-
140
-
-
71049144941
-
STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect
-
[140] Pitroda, S.P., Wakim, B.T., Sood, R.F., Beveridge, M.G., Beckett, M.A., MacDermed, D.M., et al. STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect. BMC Med., 7, 2009, 68.
-
(2009)
BMC Med.
, vol.7
, pp. 68
-
-
Pitroda, S.P.1
Wakim, B.T.2
Sood, R.F.3
Beveridge, M.G.4
Beckett, M.A.5
MacDermed, D.M.6
-
141
-
-
12444279265
-
On the origin of cancer cells
-
[141] Warburg, O., On the origin of cancer cells. Science 123 (1956), 309–314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
142
-
-
84858604270
-
Metabolic reprogramming: a cancer hallmark even warburg did not anticipate
-
[142] Ward, P.S., Thompson, C.B., Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 21 (2012), 297–308.
-
(2012)
Cancer Cell
, vol.21
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
143
-
-
84916637192
-
Upregulation of Stat1-HDAC4 confers resistance to etoposide through enhanced multidrug resistance 1 expression in human A549 lung cancer cells
-
[143] Kaewpiboon, C., Srisuttee, R., Malilas, W., Moon, J., Oh, S., Jeong, H.G., et al. Upregulation of Stat1-HDAC4 confers resistance to etoposide through enhanced multidrug resistance 1 expression in human A549 lung cancer cells. Mol. Med. Rep. 11 (2015), 2315–2321.
-
(2015)
Mol. Med. Rep.
, vol.11
, pp. 2315-2321
-
-
Kaewpiboon, C.1
Srisuttee, R.2
Malilas, W.3
Moon, J.4
Oh, S.5
Jeong, H.G.6
-
144
-
-
84877344922
-
IFNB1/interferon-beta-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function
-
[144] Ambjorn, M., Ejlerskov, P., Liu, Y., Lees, M., Jaattela, M., Issazadeh-Navikas, S., IFNB1/interferon-beta-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function. Autophagy 9 (2013), 287–302.
-
(2013)
Autophagy
, vol.9
, pp. 287-302
-
-
Ambjorn, M.1
Ejlerskov, P.2
Liu, Y.3
Lees, M.4
Jaattela, M.5
Issazadeh-Navikas, S.6
-
145
-
-
84887270621
-
Suppression of autophagy enhanced growth inhibition and apoptosis of interferon-beta in human glioma cells
-
[145] Li, Y., Zhu, H., Zeng, X., Fan, J., Qian, X., Wang, S., et al. Suppression of autophagy enhanced growth inhibition and apoptosis of interferon-beta in human glioma cells. Mol. Neurobiol. 47 (2013), 1000–1010.
-
(2013)
Mol. Neurobiol.
, vol.47
, pp. 1000-1010
-
-
Li, Y.1
Zhu, H.2
Zeng, X.3
Fan, J.4
Qian, X.5
Wang, S.6
-
146
-
-
84877337914
-
Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNalpha in chronic myeloid leukemia cells
-
[146] Zhu, S., Cao, L., Yu, Y., Yang, L., Yang, M., Liu, K., et al. Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNalpha in chronic myeloid leukemia cells. Autophagy 9 (2013), 317–327.
-
(2013)
Autophagy
, vol.9
, pp. 317-327
-
-
Zhu, S.1
Cao, L.2
Yu, Y.3
Yang, L.4
Yang, M.5
Liu, K.6
-
147
-
-
84945562319
-
Interferon-regulatory factor-1 (IRF1) regulates bevacizumab induced autophagy
-
[147] Liang, J., Piao, Y., Henry, V., Tiao, N., de Groot, J.F., Interferon-regulatory factor-1 (IRF1) regulates bevacizumab induced autophagy. Oncotarget 6 (2015), 31479–31492.
-
(2015)
Oncotarget
, vol.6
, pp. 31479-31492
-
-
Liang, J.1
Piao, Y.2
Henry, V.3
Tiao, N.4
de Groot, J.F.5
-
148
-
-
84928687256
-
Stat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugs
-
[148] Wang, S., Patsis, C., Koromilas, A.E., Stat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugs. Proc. Natl. Acad. Sci. USA 112 (2015), E2149–E2155.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. E2149-E2155
-
-
Wang, S.1
Patsis, C.2
Koromilas, A.E.3
-
149
-
-
67149125785
-
Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling
-
[149] Efimova, E.V., Liang, H., Pitroda, S.P., Labay, E., Darga, T.E., Levina, V., et al. Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int. J. Radiat. Biol. 85 (2009), 421–431.
-
(2009)
Int. J. Radiat. Biol.
, vol.85
, pp. 421-431
-
-
Efimova, E.V.1
Liang, H.2
Pitroda, S.P.3
Labay, E.4
Darga, T.E.5
Levina, V.6
-
150
-
-
84883830323
-
STAT1 and STAT3 in tumorigenesis: a matter of balance
-
[150] Avalle, L., Pensa, S., Regis, G., Novelli, F., Poli, V., STAT1 and STAT3 in tumorigenesis: a matter of balance. JAKSTAT 1 (2012), 65–72.
-
(2012)
JAKSTAT
, vol.1
, pp. 65-72
-
-
Avalle, L.1
Pensa, S.2
Regis, G.3
Novelli, F.4
Poli, V.5
-
151
-
-
52949136974
-
Ups and downs: the STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling
-
[151] Regis, G., Pensa, S., Boselli, D., Novelli, F., Poli, V., Ups and downs: the STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling. Semin. Cell Dev. Biol. 19 (2008), 351–359.
-
(2008)
Semin. Cell Dev. Biol.
, vol.19
, pp. 351-359
-
-
Regis, G.1
Pensa, S.2
Boselli, D.3
Novelli, F.4
Poli, V.5
-
152
-
-
85001700625
-
A STAT inhibitor patent review: progress since
-
[152] Lai, P.S., Rosa, D.A., Magdy Ali, A., Gomez-Biagi, R.F., Ball, D.P., Shouksmith, A.E., et al. A STAT inhibitor patent review: progress since. Expert Opin. Ther. Pat. 2015 (2011), 1–25.
-
(2011)
Expert Opin. Ther. Pat.
, vol.2015
, pp. 1-25
-
-
Lai, P.S.1
Rosa, D.A.2
Magdy Ali, A.3
Gomez-Biagi, R.F.4
Ball, D.P.5
Shouksmith, A.E.6
-
153
-
-
84923352598
-
Identification of STAT1 and STAT3 specific inhibitors using comparative virtual screening and docking validation
-
[153] Szelag, M., Czerwoniec, A., Wesoly, J., Bluyssen, H.A., Identification of STAT1 and STAT3 specific inhibitors using comparative virtual screening and docking validation. PLoS One, 10, 2015, e0116688.
-
(2015)
PLoS One
, vol.10
, pp. e0116688
-
-
Szelag, M.1
Czerwoniec, A.2
Wesoly, J.3
Bluyssen, H.A.4
-
154
-
-
84933277745
-
Type I interferons in anticancer immunity
-
[154] Zitvogel, L., Galluzzi, L., Kepp, O., Smyth, M.J., Kroemer, G., Type I interferons in anticancer immunity. Nat. RevImmunol. 15 (2015), 405–414.
-
(2015)
Nat. RevImmunol.
, vol.15
, pp. 405-414
-
-
Zitvogel, L.1
Galluzzi, L.2
Kepp, O.3
Smyth, M.J.4
Kroemer, G.5
-
155
-
-
84876114298
-
Interferon-gamma-induced necrosis: an antitumor biotherapeutic perspective
-
[155] Balachandran, S., Adams, G.P., Interferon-gamma-induced necrosis: an antitumor biotherapeutic perspective. J. Interferon. Cytokine Res. 33 (2013), 171–180.
-
(2013)
J. Interferon. Cytokine Res.
, vol.33
, pp. 171-180
-
-
Balachandran, S.1
Adams, G.P.2
-
156
-
-
84929023079
-
Investigations of interferon-lambda for the treatment of cancer
-
[156] Stiff, A., Carson, W. III, Investigations of interferon-lambda for the treatment of cancer. J. Innate. Immun. 7 (2015), 243–250.
-
(2015)
J. Innate. Immun.
, vol.7
, pp. 243-250
-
-
Stiff, A.1
Carson, W.2
-
157
-
-
84937000772
-
Interleukin-35: expanding its job profile
-
[157] Sawant, D.V., Hamilton, K., Vignali, D.A., Interleukin-35: expanding its job profile. J. Interferon. Cytokine Res. 35 (2015), 499–512.
-
(2015)
J. Interferon. Cytokine Res.
, vol.35
, pp. 499-512
-
-
Sawant, D.V.1
Hamilton, K.2
Vignali, D.A.3
-
158
-
-
84942193300
-
Potential clinical application of interleukin-27 as an antitumor agent
-
[158] Yoshimoto, T., Chiba, Y., Furusawa, J., Xu, M., Tsunoda, R., Higuchi, K., et al. Potential clinical application of interleukin-27 as an antitumor agent. Cancer Sci. 106 (2015), 1103–1110.
-
(2015)
Cancer Sci.
, vol.106
, pp. 1103-1110
-
-
Yoshimoto, T.1
Chiba, Y.2
Furusawa, J.3
Xu, M.4
Tsunoda, R.5
Higuchi, K.6
-
159
-
-
84921609249
-
The role of IL-21 in immunity and cancer
-
[159] Davis, M.R., Zhu, Z., Hansen, D.M., Bai, Q., Fang, Y., The role of IL-21 in immunity and cancer. Cancer Lett. 358 (2015), 107–114.
-
(2015)
Cancer Lett.
, vol.358
, pp. 107-114
-
-
Davis, M.R.1
Zhu, Z.2
Hansen, D.M.3
Bai, Q.4
Fang, Y.5
|