메뉴 건너뛰기




Volumn 14, Issue 1, 2014, Pages

High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

CD163 ANTIGEN; CD45 ANTIGEN; CD68 ANTIGEN; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON REGULATORY FACTOR 1; MESSENGER RNA; PROGRAMMED DEATH 1 RECEPTOR; SERINE; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRANSCRIPTION FACTOR FOXP3; TYROSINE; STAT1 PROTEIN, HUMAN;

EID: 84899472350     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-257     Document Type: Article
Times cited : (66)

References (56)
  • 1
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • 10.1038/nri1961, 17063185
    • Dunn GP, Koebel CM, Schreiber RD. Interferons, immunity and cancer immunoediting. Nat Rev Immunol 2006, 6(11):836-848. 10.1038/nri1961, 17063185.
    • (2006) Nat Rev Immunol , vol.6 , Issue.11 , pp. 836-848
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 2
    • 77049092286 scopus 로고    scopus 로고
    • Gene modulation and immunoregulatory roles of interferon gamma
    • 10.1016/j.cyto.2009.11.021, 20036577
    • Saha B, Jyothi Prasanna S, Chandrasekar B, Nandi D. Gene modulation and immunoregulatory roles of interferon gamma. Cytokine 2010, 50(1):1-14. 10.1016/j.cyto.2009.11.021, 20036577.
    • (2010) Cytokine , vol.50 , Issue.1 , pp. 1-14
    • Saha, B.1    Jyothi Prasanna, S.2    Chandrasekar, B.3    Nandi, D.4
  • 3
    • 0036476551 scopus 로고    scopus 로고
    • Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling
    • 10.1016/S1471-4906(01)02118-4, 11929133
    • Ramana CV, Gil MP, Schreiber RD, Stark GR. Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling. Trends Immunol 2002, 23(2):96-101. 10.1016/S1471-4906(01)02118-4, 11929133.
    • (2002) Trends Immunol , vol.23 , Issue.2 , pp. 96-101
    • Ramana, C.V.1    Gil, M.P.2    Schreiber, R.D.3    Stark, G.R.4
  • 4
    • 77951025336 scopus 로고    scopus 로고
    • STAT1 and pathogens, not a friendly relationship
    • 10.1016/j.biochi.2010.02.009, 20159032
    • Najjar I, Fagard R. STAT1 and pathogens, not a friendly relationship. Biochimie 2010, 92(5):425-444. 10.1016/j.biochi.2010.02.009, 20159032.
    • (2010) Biochimie , vol.92 , Issue.5 , pp. 425-444
    • Najjar, I.1    Fagard, R.2
  • 6
    • 70350525361 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 1 in T cells plays an indispensable role in immunity to Leishmania major by mediating Th1 cell homing to the site of infection
    • 10.1096/fj.09-138057, 2775013, 19641143
    • Barbi J, Snider HM, Bhardwaj N, Lezama-Davila CM, Durbin JE, Satoskar AR. Signal transducer and activator of transcription 1 in T cells plays an indispensable role in immunity to Leishmania major by mediating Th1 cell homing to the site of infection. FASEB J 2009, 23(11):3990-3999. 10.1096/fj.09-138057, 2775013, 19641143.
    • (2009) FASEB J , vol.23 , Issue.11 , pp. 3990-3999
    • Barbi, J.1    Snider, H.M.2    Bhardwaj, N.3    Lezama-Davila, C.M.4    Durbin, J.E.5    Satoskar, A.R.6
  • 7
    • 42149149899 scopus 로고    scopus 로고
    • STAT1 signaling in CD8 T cells is required for their clonal expansion and memory formation following viral infection in vivo
    • 10.4049/jimmunol.180.4.2158, 18250422
    • Quigley M, Huang X, Yang Y. STAT1 signaling in CD8 T cells is required for their clonal expansion and memory formation following viral infection in vivo. J Immunol 2008, 180(4):2158-2164. 10.4049/jimmunol.180.4.2158, 18250422.
    • (2008) J Immunol , vol.180 , Issue.4 , pp. 2158-2164
    • Quigley, M.1    Huang, X.2    Yang, Y.3
  • 8
    • 78449258706 scopus 로고    scopus 로고
    • Loss of STAT1 from mouse mammary epithelium results in an increased neu-induced tumor burden
    • 2978912, 21076615
    • Klover PJ, Muller WJ, Robinson GW, Pfeiffer RM, Yamaji D, Hennighausen L. Loss of STAT1 from mouse mammary epithelium results in an increased neu-induced tumor burden. Neoplasia 2010, 12(11):899-905. 2978912, 21076615.
    • (2010) Neoplasia , vol.12 , Issue.11 , pp. 899-905
    • Klover, P.J.1    Muller, W.J.2    Robinson, G.W.3    Pfeiffer, R.M.4    Yamaji, D.5    Hennighausen, L.6
  • 9
    • 79952344515 scopus 로고    scopus 로고
    • Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation
    • 10.4161/cc.10.5.14956, 21311224
    • Raven JF, Williams V, Wang S, Tremblay ML, Muller WJ, Durbin JE, Koromilas AE. Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation. Cell Cycle 2011, 10(5):794-804. 10.4161/cc.10.5.14956, 21311224.
    • (2011) Cell Cycle , vol.10 , Issue.5 , pp. 794-804
    • Raven, J.F.1    Williams, V.2    Wang, S.3    Tremblay, M.L.4    Muller, W.J.5    Durbin, J.E.6    Koromilas, A.E.7
  • 10
    • 33846202008 scopus 로고    scopus 로고
    • STAT1 as a key modulator of cell death
    • 10.1016/j.cellsig.2006.09.003, 17085014
    • Kim HS, Lee MS. STAT1 as a key modulator of cell death. Cell Signal 2007, 19(3):454-465. 10.1016/j.cellsig.2006.09.003, 17085014.
    • (2007) Cell Signal , vol.19 , Issue.3 , pp. 454-465
    • Kim, H.S.1    Lee, M.S.2
  • 13
    • 84898910134 scopus 로고    scopus 로고
    • The tumor suppressor function of STAT1 in breast cancer
    • 3710319, 24058806
    • Koromilas AE, Sexl V. The tumor suppressor function of STAT1 in breast cancer. JAKSTAT 2013, 2(2):e23353. 3710319, 24058806.
    • (2013) JAKSTAT , vol.2 , Issue.2
    • Koromilas, A.E.1    Sexl, V.2
  • 15
    • 67149125785 scopus 로고    scopus 로고
    • Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling
    • 10.1080/09553000902838566, 2690884, 19437244
    • Efimova EV, Liang H, Pitroda SP, Labay E, Darga TE, Levina V, Lokshin A, Roizman B, Weichselbaum RR, Khodarev NN. Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int J Radiat Biol 2009, 85(5):421-431. 10.1080/09553000902838566, 2690884, 19437244.
    • (2009) Int J Radiat Biol , vol.85 , Issue.5 , pp. 421-431
    • Efimova, E.V.1    Liang, H.2    Pitroda, S.P.3    Labay, E.4    Darga, T.E.5    Levina, V.6    Lokshin, A.7    Roizman, B.8    Weichselbaum, R.R.9    Khodarev, N.N.10
  • 18
    • 84876921278 scopus 로고    scopus 로고
    • Tumor STAT1 transcription factor activity enhances breast tumor growth and immune suppression mediated by myeloid-derived suppressor cells
    • Hix LM, Karavitis J, Khan MW, Shi YH, Khazaie K, Zhang M. Tumor STAT1 transcription factor activity enhances breast tumor growth and immune suppression mediated by myeloid-derived suppressor cells. J Biol Chem 2013, 288(17):11676-11688.
    • (2013) J Biol Chem , vol.288 , Issue.17 , pp. 11676-11688
    • Hix, L.M.1    Karavitis, J.2    Khan, M.W.3    Shi, Y.H.4    Khazaie, K.5    Zhang, M.6
  • 19
    • 84861790681 scopus 로고    scopus 로고
    • Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth
    • 10.1158/1078-0432.CCR-11-3225, 22615451
    • Khodarev NN, Roizman B, Weichselbaum RR. Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth. Clin Cancer Res 2012, 18(11):3015-3021. 10.1158/1078-0432.CCR-11-3225, 22615451.
    • (2012) Clin Cancer Res , vol.18 , Issue.11 , pp. 3015-3021
    • Khodarev, N.N.1    Roizman, B.2    Weichselbaum, R.R.3
  • 20
    • 0036793979 scopus 로고    scopus 로고
    • Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer
    • Widschwendter A, Tonko-Geymayer S, Welte T, Daxenbichler G, Marth C, Doppler W. Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer. Clin Cancer Res 2002, 8(10):3065-3074.
    • (2002) Clin Cancer Res , vol.8 , Issue.10 , pp. 3065-3074
    • Widschwendter, A.1    Tonko-Geymayer, S.2    Welte, T.3    Daxenbichler, G.4    Marth, C.5    Doppler, W.6
  • 21
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression
    • 10.1186/bcr1746, 2206719, 17705880
    • DeNardo DG, Coussens LM. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res 2007, 9(4):212. 10.1186/bcr1746, 2206719, 17705880.
    • (2007) Breast Cancer Res , vol.9 , Issue.4 , pp. 212
    • DeNardo, D.G.1    Coussens, L.M.2
  • 23
    • 80053133049 scopus 로고    scopus 로고
    • Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response
    • 10.1038/nri3062, 21904387
    • King KY, Goodell MA. Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol 2011, 11(10):685-692. 10.1038/nri3062, 21904387.
    • (2011) Nat Rev Immunol , vol.11 , Issue.10 , pp. 685-692
    • King, K.Y.1    Goodell, M.A.2
  • 24
    • 8544283773 scopus 로고    scopus 로고
    • Interferon-gamma expression is an independent prognostic factor in ovarian cancer
    • 10.1016/j.ajog.2004.05.007, 15547530
    • Marth C, Fiegl H, Zeimet AG, Muller-Holzner E, Deibl M, Doppler W, Daxenbichler G. Interferon-gamma expression is an independent prognostic factor in ovarian cancer. Am J Obstet Gynecol 2004, 191(5):1598-1605. 10.1016/j.ajog.2004.05.007, 15547530.
    • (2004) Am J Obstet Gynecol , vol.191 , Issue.5 , pp. 1598-1605
    • Marth, C.1    Fiegl, H.2    Zeimet, A.G.3    Muller-Holzner, E.4    Deibl, M.5    Doppler, W.6    Daxenbichler, G.7
  • 26
    • 66649113947 scopus 로고    scopus 로고
    • Selective response to insulin versus insulin-like growth factor-I and -II and up-regulation of insulin receptor splice variant B in the differentiated mouse mammary epithelium
    • 10.1210/en.2008-0668, 19246539
    • Berlato C, Doppler W. Selective response to insulin versus insulin-like growth factor-I and -II and up-regulation of insulin receptor splice variant B in the differentiated mouse mammary epithelium. Endocrinology 2009, 150(6):2924-2933. 10.1210/en.2008-0668, 19246539.
    • (2009) Endocrinology , vol.150 , Issue.6 , pp. 2924-2933
    • Berlato, C.1    Doppler, W.2
  • 27
    • 0036169031 scopus 로고    scopus 로고
    • Genesis: cluster analysis of microarray data
    • 10.1093/bioinformatics/18.1.207, 11836235
    • Sturn A, Quackenbush J, Trajanoski Z. Genesis: cluster analysis of microarray data. Bioinformatics 2002, 18(1):207-208. 10.1093/bioinformatics/18.1.207, 11836235.
    • (2002) Bioinformatics , vol.18 , Issue.1 , pp. 207-208
    • Sturn, A.1    Quackenbush, J.2    Trajanoski, Z.3
  • 29
    • 84884686329 scopus 로고    scopus 로고
    • Negligible nuclear FOXP3 expression in breast cancer epithelial cells compared with FOXP3-positive T cells
    • 10.1016/j.clbc.2013.02.009, 23829892
    • Droeser RA, Obermann EC, Wolf AM, Wallner S, Wolf D, Tzankov A. Negligible nuclear FOXP3 expression in breast cancer epithelial cells compared with FOXP3-positive T cells. Clin Breast Cancer 2013, 13(4):264-270. 10.1016/j.clbc.2013.02.009, 23829892.
    • (2013) Clin Breast Cancer , vol.13 , Issue.4 , pp. 264-270
    • Droeser, R.A.1    Obermann, E.C.2    Wolf, A.M.3    Wallner, S.4    Wolf, D.5    Tzankov, A.6
  • 30
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • 10.1038/nrc3239, 22437870
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012, 12(4):252-264. 10.1038/nrc3239, 22437870.
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 252-264
    • Pardoll, D.M.1
  • 31
    • 84859158384 scopus 로고    scopus 로고
    • Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
    • 10.1016/j.coi.2011.12.009, 3319479, 22236695
    • Topalian SL, Drake CG, Pardoll DM. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol 2012, 24(2):207-212. 10.1016/j.coi.2011.12.009, 3319479, 22236695.
    • (2012) Curr Opin Immunol , vol.24 , Issue.2 , pp. 207-212
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 33
    • 37549016755 scopus 로고    scopus 로고
    • The production of interferon-gamma-inducible protein 10 by granulocytes and monocytes is associated with ulcerative colitis disease activity
    • 10.1007/s00535-007-2118-9, 18085351
    • Noguchi A, Watanabe K, Narumi S, Yamagami H, Fujiwara Y, Higuchi K, Oshitani N, Arakawa T. The production of interferon-gamma-inducible protein 10 by granulocytes and monocytes is associated with ulcerative colitis disease activity. J Gastroenterol 2007, 42(12):947-956. 10.1007/s00535-007-2118-9, 18085351.
    • (2007) J Gastroenterol , vol.42 , Issue.12 , pp. 947-956
    • Noguchi, A.1    Watanabe, K.2    Narumi, S.3    Yamagami, H.4    Fujiwara, Y.5    Higuchi, K.6    Oshitani, N.7    Arakawa, T.8
  • 34
    • 0041825409 scopus 로고    scopus 로고
    • Increased serum levels of interferon-gamma-inducible protein 10 and monokine induced by gamma interferon in patients with haemophagocytic lymphohistiocytosis
    • 10.1046/j.1365-2249.2003.02237.x, 1808805, 12930373
    • Takada H, Takahata Y, Nomura A, Ohga S, Mizuno Y, Hara T. Increased serum levels of interferon-gamma-inducible protein 10 and monokine induced by gamma interferon in patients with haemophagocytic lymphohistiocytosis. Clin Exp Immunol 2003, 133(3):448-453. 10.1046/j.1365-2249.2003.02237.x, 1808805, 12930373.
    • (2003) Clin Exp Immunol , vol.133 , Issue.3 , pp. 448-453
    • Takada, H.1    Takahata, Y.2    Nomura, A.3    Ohga, S.4    Mizuno, Y.5    Hara, T.6
  • 35
    • 0035723756 scopus 로고    scopus 로고
    • Clinical significance of elevated serum interferon- inducible protein-10 levels in hepatitis C virus carriers with persistently normal serum transaminase levels
    • 10.1046/j.1365-2893.2001.00309.x, 11555191
    • Itoh Y, Morita A, Nishioji K, Narumi S, Toyama T, Daimon Y, Nakamura H, Kirishima T, Okanoue T. Clinical significance of elevated serum interferon- inducible protein-10 levels in hepatitis C virus carriers with persistently normal serum transaminase levels. J Viral Hepat 2001, 8(5):341-348. 10.1046/j.1365-2893.2001.00309.x, 11555191.
    • (2001) J Viral Hepat , vol.8 , Issue.5 , pp. 341-348
    • Itoh, Y.1    Morita, A.2    Nishioji, K.3    Narumi, S.4    Toyama, T.5    Daimon, Y.6    Nakamura, H.7    Kirishima, T.8    Okanoue, T.9
  • 36
    • 61349166620 scopus 로고    scopus 로고
    • CXCL10 and autoimmune diseases
    • 10.1016/j.autrev.2008.12.002, 19105984
    • Lee EY, Lee ZH, Song YW. CXCL10 and autoimmune diseases. Autoimmun Rev 2009, 8(5):379-383. 10.1016/j.autrev.2008.12.002, 19105984.
    • (2009) Autoimmun Rev , vol.8 , Issue.5 , pp. 379-383
    • Lee, E.Y.1    Lee, Z.H.2    Song, Y.W.3
  • 38
    • 84866381896 scopus 로고    scopus 로고
    • Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance
    • 10.1158/0008-5472.CAN-12-1347, 3564959, 22805310
    • Zimmerman MA, Rahman NT, Yang D, Lahat G, Lazar AJ, Pollock RE, Lev D, Liu K. Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance. Cancer Res 2012, 72(18):4724-4732. 10.1158/0008-5472.CAN-12-1347, 3564959, 22805310.
    • (2012) Cancer Res , vol.72 , Issue.18 , pp. 4724-4732
    • Zimmerman, M.A.1    Rahman, N.T.2    Yang, D.3    Lahat, G.4    Lazar, A.J.5    Pollock, R.E.6    Lev, D.7    Liu, K.8
  • 39
    • 67249132591 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-{gamma} signaling
    • 10.1073/pnas.0812109106, 2695062, 19474293
    • Heinonen KM, Bourdeau A, Doody KM, Tremblay ML. Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-{gamma} signaling. Proc Natl Acad Sci U S A 2009, 106(23):9368-9372. 10.1073/pnas.0812109106, 2695062, 19474293.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.23 , pp. 9368-9372
    • Heinonen, K.M.1    Bourdeau, A.2    Doody, K.M.3    Tremblay, M.L.4
  • 40
    • 0029972194 scopus 로고    scopus 로고
    • The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase
    • 452449, 8947049
    • Haspel RL, Salditt-Georgieff M, Darnell JE. The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J 1996, 15(22):6262-6268. 452449, 8947049.
    • (1996) EMBO J , vol.15 , Issue.22 , pp. 6262-6268
    • Haspel, R.L.1    Salditt-Georgieff, M.2    Darnell, J.E.3
  • 41
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • 10.1038/nri2093, 17525754
    • Yoshimura A, Naka T, Kubo M. SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol 2007, 7(6):454-465. 10.1038/nri2093, 17525754.
    • (2007) Nat Rev Immunol , vol.7 , Issue.6 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 42
    • 0036731485 scopus 로고    scopus 로고
    • Stats: transcriptional control and biological impact
    • 10.1038/nrm909, 12209125
    • Levy DE, Darnell JE. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002, 3(9):651-662. 10.1038/nrm909, 12209125.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.9 , pp. 651-662
    • Levy, D.E.1    Darnell, J.E.2
  • 43
    • 67249144899 scopus 로고    scopus 로고
    • Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes
    • 10.1073/pnas.0903487106, 2688000, 19478064
    • Cheon H, Stark GR. Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes. Proc Natl Acad Sci U S A 2009, 106(23):9373-9378. 10.1073/pnas.0903487106, 2688000, 19478064.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.23 , pp. 9373-9378
    • Cheon, H.1    Stark, G.R.2
  • 44
    • 78651481470 scopus 로고    scopus 로고
    • The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins
    • 10.1089/jir.2010.0100, 3021352, 21166594
    • Cheon H, Yang J, Stark GR. The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins. J Interferon Cytokine Res 2011, 31(1):33-40. 10.1089/jir.2010.0100, 3021352, 21166594.
    • (2011) J Interferon Cytokine Res , vol.31 , Issue.1 , pp. 33-40
    • Cheon, H.1    Yang, J.2    Stark, G.R.3
  • 45
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • 10.1038/sj.onc.1203481, 10851062
    • Decker T, Kovarik P. Serine phosphorylation of STATs. Oncogene 2000, 19(21):2628-2637. 10.1038/sj.onc.1203481, 10851062.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 48
    • 77951025078 scopus 로고    scopus 로고
    • Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation
    • 10.4049/jimmunol.0900331, 2916018, 19846878
    • Barnholt KE, Kota RS, Aung HH, Rutledge JC. Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation. J Immunol 2009, 183(10):6767-6777. 10.4049/jimmunol.0900331, 2916018, 19846878.
    • (2009) J Immunol , vol.183 , Issue.10 , pp. 6767-6777
    • Barnholt, K.E.1    Kota, R.S.2    Aung, H.H.3    Rutledge, J.C.4
  • 50
    • 80053422068 scopus 로고    scopus 로고
    • Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49
    • 3186362, 21859714
    • Wisskirchen C, Ludersdorfer TH, Muller DA, Moritz E, Pavlovic J. Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49. J Biol Chem 2011, 286(40):34743-34751. 3186362, 21859714.
    • (2011) J Biol Chem , vol.286 , Issue.40 , pp. 34743-34751
    • Wisskirchen, C.1    Ludersdorfer, T.H.2    Muller, D.A.3    Moritz, E.4    Pavlovic, J.5
  • 51
    • 33750305632 scopus 로고    scopus 로고
    • Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer
    • 10.1158/0008-5472.CAN-05-4345, 17018607
    • Datta D, Flaxenburg JA, Laxmanan S, Geehan C, Grimm M, Waaga-Gasser AM, Briscoe DM, Pal S. Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer. Cancer Res 2006, 66(19):9509-9518. 10.1158/0008-5472.CAN-05-4345, 17018607.
    • (2006) Cancer Res , vol.66 , Issue.19 , pp. 9509-9518
    • Datta, D.1    Flaxenburg, J.A.2    Laxmanan, S.3    Geehan, C.4    Grimm, M.5    Waaga-Gasser, A.M.6    Briscoe, D.M.7    Pal, S.8
  • 53
    • 84864828790 scopus 로고    scopus 로고
    • The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients
    • 10.1186/1471-2407-12-306, 3414782, 22824040
    • Medrek C, Ponten F, Jirstrom K, Leandersson K. The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients. BMC Cancer 2012, 12:306. 10.1186/1471-2407-12-306, 3414782, 22824040.
    • (2012) BMC Cancer , vol.12 , pp. 306
    • Medrek, C.1    Ponten, F.2    Jirstrom, K.3    Leandersson, K.4
  • 55
    • 82955217260 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
    • 10.1186/bcr3072, 3326568, 22151962
    • West NR, Milne K, Truong PT, Macpherson N, Nelson BH, Watson PH. Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer. Breast Cancer Res 2011, 13(6):R126. 10.1186/bcr3072, 3326568, 22151962.
    • (2011) Breast Cancer Res , vol.13 , Issue.6
    • West, N.R.1    Milne, K.2    Truong, P.T.3    Macpherson, N.4    Nelson, B.H.5    Watson, P.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.